ZA200806860B - Disruptions of genes encoding secreted proteins, compositions and methods relating thereto - Google Patents
Disruptions of genes encoding secreted proteins, compositions and methods relating theretoInfo
- Publication number
- ZA200806860B ZA200806860B ZA200806860A ZA200806860A ZA200806860B ZA 200806860 B ZA200806860 B ZA 200806860B ZA 200806860 A ZA200806860 A ZA 200806860A ZA 200806860 A ZA200806860 A ZA 200806860A ZA 200806860 B ZA200806860 B ZA 200806860B
- Authority
- ZA
- South Africa
- Prior art keywords
- disruptions
- compositions
- genes encoding
- secreted proteins
- methods relating
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title 2
- 239000000203 mixture Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
Classifications
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- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62378904P | 2004-10-29 | 2004-10-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200806860B true ZA200806860B (en) | 2009-07-29 |
Family
ID=36319607
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200704338A ZA200704338B (en) | 2004-10-29 | 2005-10-18 | Novel gene disruptions, compositions and methods relating thereto |
ZA200806863A ZA200806863B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806862A ZA200806862B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806860A ZA200806860B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806864A ZA200806864B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806861A ZA200806861B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806866A ZA200806866B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200704338A ZA200704338B (en) | 2004-10-29 | 2005-10-18 | Novel gene disruptions, compositions and methods relating thereto |
ZA200806863A ZA200806863B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806862A ZA200806862B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
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ZA200806864A ZA200806864B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806861A ZA200806861B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806866A ZA200806866B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
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US (2) | US7947866B2 (xx) |
EP (1) | EP1817335A2 (xx) |
JP (1) | JP2008517625A (xx) |
AU (1) | AU2005301152A1 (xx) |
CA (1) | CA2584297A1 (xx) |
WO (1) | WO2006049854A2 (xx) |
ZA (7) | ZA200704338B (xx) |
Families Citing this family (25)
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DK2069793T3 (en) | 2006-08-29 | 2017-04-24 | Oxford Biotherapeutics Ltd | IDENTIFICATION OF PROTEIN IN CONNECTION WITH HEPATOCELLULAR CARCINOMA, GLIOBLASTOMA AND LUNG CANCER |
RU2486200C2 (ru) | 2008-01-14 | 2013-06-27 | Дженентек, Инк. | Способы ингибирования ангиогенеза с помощью антагонистов egfl8 |
US8229535B2 (en) | 2008-02-21 | 2012-07-24 | Dexcom, Inc. | Systems and methods for blood glucose monitoring and alert delivery |
EA028336B1 (ru) | 2009-03-05 | 2017-11-30 | МЕДАРЕКС Л.Л.Си. | Полностью человеческие антитела, специфические в отношении cadm1 |
EP2412724A1 (en) * | 2010-07-29 | 2012-02-01 | Centre National de la Recherche Scientifique (C.N.R.S) | Regulation of Glypican 4 activity to modulate the fate of stem cells and uses thereof |
CN102807613A (zh) * | 2011-06-03 | 2012-12-05 | 北京大学 | 具有趋化活性的分泌蛋白及其医药用途 |
KR102077721B1 (ko) | 2011-07-01 | 2020-02-14 | 엔지엠 바이오파마슈티컬스, 아이엔씨. | 대사성 장애 및 질환의 치료를 위한 조성물, 용도 및 방법 |
JP6170047B2 (ja) | 2011-08-31 | 2017-07-26 | ユニバーシティ・オブ・ジョージア・リサーチ・ファウンデイション・インコーポレイテッド | アポトーシス−ターゲティングナノ粒子 |
JP6356614B2 (ja) | 2012-02-17 | 2018-07-11 | ユニバーシティ・オブ・ジョージア・リサーチ・ファウンデイション・インコーポレイテッド | 薬剤のミトコンドリア輸送のためのナノ粒子 |
WO2014085365A2 (en) | 2012-11-28 | 2014-06-05 | Ngm Biopharmaceuticals, Inc. | Compositions and methods for treatment of metabolic disorders and diseases |
US9290557B2 (en) | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
CN108888757A (zh) | 2012-12-27 | 2018-11-27 | 恩格姆生物制药公司 | 用于调节胆汁酸体内稳态及治疗胆汁酸紊乱和疾病的方法 |
US9273107B2 (en) | 2012-12-27 | 2016-03-01 | Ngm Biopharmaceuticals, Inc. | Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
WO2015065897A1 (en) | 2013-10-28 | 2015-05-07 | Ngm Biopharmaceuticals, Inc. | Cancer models and associated methods |
RU2701434C2 (ru) | 2014-01-24 | 2019-09-26 | Нгм Биофармасьютикалс, Инк. | Связывающие белки и способы их применения |
WO2015138992A1 (en) | 2014-03-14 | 2015-09-17 | University Of Georgia Research Foundation, Inc. | Mitochondrial delivery of 3-bromopyruvate |
US10398758B2 (en) | 2014-05-28 | 2019-09-03 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants of FGF19 polypeptides and uses thereof for the treatment of hyperglycemic conditions |
WO2015195509A2 (en) | 2014-06-16 | 2015-12-23 | Ngm Biopharmaceuticals, Inc. | Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
EP3209681A4 (en) | 2014-10-23 | 2018-10-31 | NGM Biopharmaceuticals, Inc. | Pharmaceutical compositions comprising peptide variants and methods of use thereof |
WO2016073855A1 (en) | 2014-11-07 | 2016-05-12 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders |
WO2017019957A2 (en) | 2015-07-29 | 2017-02-02 | Ngm Biopharmaceuticals, Inc. | Binding proteins and methods of use thereof |
US10744185B2 (en) | 2015-11-09 | 2020-08-18 | Ngm Biopharmaceuticals, Inc. | Methods of using variants of FGF19 polypeptides for the treatment of pruritus |
WO2018039557A1 (en) | 2016-08-26 | 2018-03-01 | Ngm Biopharmaceuticals, Inc. | Methods of treating fibroblast growth factor 19-mediated cancers and tumors |
CN114250194B (zh) * | 2021-11-30 | 2023-04-11 | 四川大学华西医院 | 一种急性胰腺炎细胞模型的构建方法和用途 |
CN117316293B (zh) * | 2023-11-30 | 2024-04-19 | 北京师范大学 | 基于神经影像的脑网络结构与功能耦合方法及装置 |
Family Cites Families (4)
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US20050196832A1 (en) * | 1997-09-18 | 2005-09-08 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US20030166132A1 (en) * | 1998-08-26 | 2003-09-04 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
AU2001274888A1 (en) | 2000-05-19 | 2001-12-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
AU2002364939A1 (en) * | 2001-10-22 | 2003-07-09 | Board Of Regents, The University Of Texas System | Sperm-specific cation channel, catsper2, and uses therefor |
-
2005
- 2005-10-18 EP EP05837234A patent/EP1817335A2/en not_active Withdrawn
- 2005-10-18 AU AU2005301152A patent/AU2005301152A1/en not_active Abandoned
- 2005-10-18 ZA ZA200704338A patent/ZA200704338B/xx unknown
- 2005-10-18 CA CA002584297A patent/CA2584297A1/en not_active Abandoned
- 2005-10-18 JP JP2007538976A patent/JP2008517625A/ja not_active Withdrawn
- 2005-10-18 WO PCT/US2005/037291 patent/WO2006049854A2/en active Application Filing
- 2005-10-18 US US11/577,547 patent/US7947866B2/en not_active Expired - Fee Related
-
2008
- 2008-08-08 ZA ZA200806863A patent/ZA200806863B/xx unknown
- 2008-08-08 ZA ZA200806862A patent/ZA200806862B/xx unknown
- 2008-08-08 ZA ZA200806860A patent/ZA200806860B/xx unknown
- 2008-08-08 ZA ZA200806864A patent/ZA200806864B/xx unknown
- 2008-08-08 ZA ZA200806861A patent/ZA200806861B/xx unknown
- 2008-08-08 ZA ZA200806866A patent/ZA200806866B/xx unknown
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2011
- 2011-04-08 US US13/082,706 patent/US20120210450A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
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US7947866B2 (en) | 2011-05-24 |
EP1817335A2 (en) | 2007-08-15 |
WO2006049854A2 (en) | 2006-05-11 |
WO2006049854A3 (en) | 2007-05-10 |
ZA200806861B (en) | 2009-07-29 |
JP2008517625A (ja) | 2008-05-29 |
ZA200806864B (en) | 2009-07-29 |
US20120210450A1 (en) | 2012-08-16 |
AU2005301152A1 (en) | 2006-05-11 |
US20090196876A1 (en) | 2009-08-06 |
CA2584297A1 (en) | 2006-05-11 |
ZA200704338B (en) | 2009-03-25 |
ZA200806862B (en) | 2009-07-29 |
ZA200806866B (en) | 2009-07-29 |
ZA200806863B (en) | 2009-07-29 |
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