ZA200806866B - Disruptions of genes encoding secreted proteins, compositions and methods relating thereto - Google Patents
Disruptions of genes encoding secreted proteins, compositions and methods relating theretoInfo
- Publication number
- ZA200806866B ZA200806866B ZA200806866A ZA200806866A ZA200806866B ZA 200806866 B ZA200806866 B ZA 200806866B ZA 200806866 A ZA200806866 A ZA 200806866A ZA 200806866 A ZA200806866 A ZA 200806866A ZA 200806866 B ZA200806866 B ZA 200806866B
- Authority
- ZA
- South Africa
- Prior art keywords
- disruptions
- compositions
- genes encoding
- secreted proteins
- methods relating
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title 2
- 239000000203 mixture Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
Classifications
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- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62378904P | 2004-10-29 | 2004-10-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200806866B true ZA200806866B (en) | 2009-07-29 |
Family
ID=36319607
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200704338A ZA200704338B (en) | 2004-10-29 | 2005-10-18 | Novel gene disruptions, compositions and methods relating thereto |
ZA200806860A ZA200806860B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806866A ZA200806866B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806864A ZA200806864B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806863A ZA200806863B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806861A ZA200806861B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806862A ZA200806862B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200704338A ZA200704338B (en) | 2004-10-29 | 2005-10-18 | Novel gene disruptions, compositions and methods relating thereto |
ZA200806860A ZA200806860B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
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ZA200806864A ZA200806864B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806863A ZA200806863B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806861A ZA200806861B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
ZA200806862A ZA200806862B (en) | 2004-10-29 | 2008-08-08 | Disruptions of genes encoding secreted proteins, compositions and methods relating thereto |
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EP (1) | EP1817335A2 (xx) |
JP (1) | JP2008517625A (xx) |
AU (1) | AU2005301152A1 (xx) |
CA (1) | CA2584297A1 (xx) |
WO (1) | WO2006049854A2 (xx) |
ZA (7) | ZA200704338B (xx) |
Families Citing this family (25)
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EP2069793B9 (en) | 2006-08-29 | 2017-08-16 | Oxford BioTherapeutics Ltd | Identification of protein associated with hepatocellular carcinoma, glioblastoma and lung cancer |
KR20100102152A (ko) * | 2008-01-14 | 2010-09-20 | 제넨테크, 인크. | Egfl8 길항제를 사용하여 혈관신생을 억제하는 방법 |
CA2715628A1 (en) | 2008-02-21 | 2009-08-27 | Dexcom, Inc. | Systems and methods for processing, transmitting and displaying sensor data |
JP5816558B2 (ja) | 2009-03-05 | 2015-11-18 | メダレックス・リミテッド・ライアビリティ・カンパニーMedarex, L.L.C. | Cadm1に特異的な完全ヒト抗体 |
EP2412724A1 (en) * | 2010-07-29 | 2012-02-01 | Centre National de la Recherche Scientifique (C.N.R.S) | Regulation of Glypican 4 activity to modulate the fate of stem cells and uses thereof |
CN102807613A (zh) * | 2011-06-03 | 2012-12-05 | 北京大学 | 具有趋化活性的分泌蛋白及其医药用途 |
PE20141727A1 (es) | 2011-07-01 | 2014-11-26 | Ngm Biopharmaceuticals Inc | Composiciones, usos y metodos para tratamiento de trastornos y enfermedades metabolicas |
EP2750662A4 (en) | 2011-08-31 | 2015-06-24 | Univ Georgia | NANOPARTICLES TARGETING APOPTOSIS |
ES2669561T3 (es) | 2012-02-17 | 2018-05-28 | University Of Georgia Research Foundation, Inc. | Nanopartículas para el transporte mitocondrial de agentes |
EP3798228A1 (en) | 2012-11-28 | 2021-03-31 | NGM Biopharmaceuticals, Inc. | Compositions and methods for treatment of metabolic disorders and diseases |
US9290557B2 (en) | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
US9273107B2 (en) | 2012-12-27 | 2016-03-01 | Ngm Biopharmaceuticals, Inc. | Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
AU2013370404B2 (en) | 2012-12-27 | 2017-11-02 | Ngm Biopharmaceuticals, Inc. | Methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
AU2014342630B2 (en) | 2013-10-28 | 2020-11-05 | Ngm Biopharmaceuticals, Inc. | Cancer models and associated methods |
CN106662577B (zh) | 2014-01-24 | 2020-07-21 | 恩格姆生物制药公司 | 结合蛋白及其使用方法 |
WO2015138992A1 (en) | 2014-03-14 | 2015-09-17 | University Of Georgia Research Foundation, Inc. | Mitochondrial delivery of 3-bromopyruvate |
US10398758B2 (en) | 2014-05-28 | 2019-09-03 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants of FGF19 polypeptides and uses thereof for the treatment of hyperglycemic conditions |
US10456449B2 (en) | 2014-06-16 | 2019-10-29 | Ngm Biopharmaceuticals, Inc. | Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
SG11201702757YA (en) | 2014-10-23 | 2017-05-30 | Ngm Biopharmaceuticals Inc | Pharmaceutical compositions comprising peptide variants and methods of use thereof |
US10434144B2 (en) | 2014-11-07 | 2019-10-08 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders |
US10800843B2 (en) | 2015-07-29 | 2020-10-13 | Ngm Biopharmaceuticals, Inc. | Beta klotho-binding proteins |
ES2871036T3 (es) | 2015-11-09 | 2021-10-28 | Ngm Biopharmaceuticals Inc | Método para el tratamiento de trastornos relacionados con ácidos biliares |
US11370841B2 (en) | 2016-08-26 | 2022-06-28 | Ngm Biopharmaceuticals, Inc. | Methods of treating fibroblast growth factor 19-mediated cancers and tumors |
CN114250194B (zh) * | 2021-11-30 | 2023-04-11 | 四川大学华西医院 | 一种急性胰腺炎细胞模型的构建方法和用途 |
CN117316293B (zh) * | 2023-11-30 | 2024-04-19 | 北京师范大学 | 基于神经影像的脑网络结构与功能耦合方法及装置 |
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US20050196832A1 (en) * | 1997-09-18 | 2005-09-08 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US20030166132A1 (en) * | 1998-08-26 | 2003-09-04 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO2001090304A2 (en) | 2000-05-19 | 2001-11-29 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
JP2005512561A (ja) * | 2001-10-22 | 2005-05-12 | チルドレンズ・メディカル・センター・コーポレイション | 精子特異的カチオンチャネル、catsper2およびそれらの使用法 |
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2005
- 2005-10-18 ZA ZA200704338A patent/ZA200704338B/xx unknown
- 2005-10-18 JP JP2007538976A patent/JP2008517625A/ja not_active Withdrawn
- 2005-10-18 EP EP05837234A patent/EP1817335A2/en not_active Withdrawn
- 2005-10-18 AU AU2005301152A patent/AU2005301152A1/en not_active Abandoned
- 2005-10-18 CA CA002584297A patent/CA2584297A1/en not_active Abandoned
- 2005-10-18 US US11/577,547 patent/US7947866B2/en not_active Expired - Fee Related
- 2005-10-18 WO PCT/US2005/037291 patent/WO2006049854A2/en active Application Filing
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2008
- 2008-08-08 ZA ZA200806860A patent/ZA200806860B/xx unknown
- 2008-08-08 ZA ZA200806866A patent/ZA200806866B/xx unknown
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- 2008-08-08 ZA ZA200806863A patent/ZA200806863B/xx unknown
- 2008-08-08 ZA ZA200806861A patent/ZA200806861B/xx unknown
- 2008-08-08 ZA ZA200806862A patent/ZA200806862B/xx unknown
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2011
- 2011-04-08 US US13/082,706 patent/US20120210450A1/en not_active Abandoned
Also Published As
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AU2005301152A1 (en) | 2006-05-11 |
WO2006049854A3 (en) | 2007-05-10 |
CA2584297A1 (en) | 2006-05-11 |
US20120210450A1 (en) | 2012-08-16 |
ZA200806862B (en) | 2009-07-29 |
EP1817335A2 (en) | 2007-08-15 |
US20090196876A1 (en) | 2009-08-06 |
US7947866B2 (en) | 2011-05-24 |
ZA200806864B (en) | 2009-07-29 |
ZA200704338B (en) | 2009-03-25 |
ZA200806863B (en) | 2009-07-29 |
ZA200806860B (en) | 2009-07-29 |
ZA200806861B (en) | 2009-07-29 |
WO2006049854A2 (en) | 2006-05-11 |
JP2008517625A (ja) | 2008-05-29 |
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