ZA200802436B - Composition comprising a NSAID and paracetamol - Google Patents

Composition comprising a NSAID and paracetamol

Info

Publication number
ZA200802436B
ZA200802436B ZA200802436A ZA200802436A ZA200802436B ZA 200802436 B ZA200802436 B ZA 200802436B ZA 200802436 A ZA200802436 A ZA 200802436A ZA 200802436 A ZA200802436 A ZA 200802436A ZA 200802436 B ZA200802436 B ZA 200802436B
Authority
ZA
South Africa
Prior art keywords
paracetamol
nsaid
composition
Prior art date
Application number
ZA200802436A
Other languages
English (en)
Inventor
Sherry Robert
Original Assignee
Uk Reckitt Benckiser Healthcar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uk Reckitt Benckiser Healthcar filed Critical Uk Reckitt Benckiser Healthcar
Publication of ZA200802436B publication Critical patent/ZA200802436B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
ZA200802436A 2005-09-22 2008-03-17 Composition comprising a NSAID and paracetamol ZA200802436B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0519350.3A GB0519350D0 (en) 2005-09-22 2005-09-22 Therapeutic agents

Publications (1)

Publication Number Publication Date
ZA200802436B true ZA200802436B (en) 2009-07-29

Family

ID=35335274

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200802436A ZA200802436B (en) 2005-09-22 2008-03-17 Composition comprising a NSAID and paracetamol

Country Status (13)

Country Link
US (1) US20090142392A1 (ja)
EP (2) EP1926477B1 (ja)
JP (1) JP2009508916A (ja)
KR (2) KR101434906B1 (ja)
CN (1) CN101267807B (ja)
AU (1) AU2006293798B2 (ja)
CA (1) CA2623281A1 (ja)
GB (1) GB0519350D0 (ja)
PL (2) PL2851068T3 (ja)
RU (1) RU2438656C2 (ja)
SG (1) SG149080A1 (ja)
WO (1) WO2007034135A1 (ja)
ZA (1) ZA200802436B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080275125A1 (en) 2004-07-07 2008-11-06 Aft Pharmaceuticals Limited Combination Composition
GB2447898B (en) * 2007-03-24 2011-08-17 Reckitt Benckiser Healthcare A tablet having improved stability with at least two actives
KR20100134557A (ko) * 2008-01-11 2010-12-23 씨아이피엘에이 엘티디. 고체 약제학적 투여 제형
JPWO2009128543A1 (ja) * 2008-04-17 2011-08-04 ニプロ株式会社 シリカを含む錠剤の製造方法、錠剤及び錠剤用複合粒子
JP2012505830A (ja) 2008-10-14 2012-03-08 エイエフティ ファーマスーティカルズ リミテッド 医薬品及び医薬品治療
ES2365961B1 (es) * 2010-03-30 2013-01-24 Farmasierra Manufacturing S.L. Formulación farmacéutica a base de ibuprofeno y codeína de estabilidad mejorada.
CN105816434B (zh) * 2016-04-19 2019-09-17 山东新华制药股份有限公司 布洛芬颗粒及其制备方法
WO2019108147A1 (en) 2017-11-29 2019-06-06 İlko İlaç Sanayi̇ Ve Ti̇caret A.Ş. Color stable fixed dose tablet combination of ibuprofen and paracetamol
US20190350883A1 (en) * 2018-05-20 2019-11-21 Luan Chau Pharmaceutical Composition of Acetaminophen/Ibuprofen
US11197830B2 (en) 2019-02-27 2021-12-14 Aft Pharmaceuticals Limited Pharmaceutical composition containing acetaminophen and ibuprofen
US11779541B2 (en) 2019-03-26 2023-10-10 Johnson & Johnson Consumer Inc. Immediate release dosage form
US11918693B2 (en) * 2019-06-27 2024-03-05 Haleon Us Holdings Llc Ibuprofen and acetaminophen tablet
CN110372713B (zh) * 2019-08-15 2022-05-17 广州市汉普医药有限公司 一种普拉洛芬的精制纯化方法
WO2023281089A2 (en) 2021-07-08 2023-01-12 Krka, D.D., Novo Mesto Pharmaceutical composition comprising naproxen and paracetamol

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5271811A (en) * 1988-01-29 1993-12-21 Hoechst Celanese Corporation Process for purifying 2-(4-isobutylphenyl)-propionic acid by vacuum distillation
DE3802619C1 (ja) 1988-01-29 1989-09-07 Hoechst Ag, 6230 Frankfurt, De
DE3833448A1 (de) 1988-10-01 1990-04-12 Hoechst Ag Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung
US5409709A (en) * 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen
JP3122748B2 (ja) * 1991-11-29 2001-01-09 ライオン株式会社 イブプロフェン含有解熱鎮痛剤
DE4418837A1 (de) * 1994-05-30 1995-12-07 Bayer Ag Thermisches Granulierverfahren
JP3982889B2 (ja) * 1997-11-28 2007-09-26 あすか製薬株式会社 イブプロフェン含有医薬製剤
US6787157B1 (en) * 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
CZ300558B6 (cs) * 1999-12-09 2009-06-17 Reckitt Benckiser Healthcare (Uk) Limited Tabletová kompozice nesteroidního protizánetlivého léciva a zpusob její prípravy
GB0113841D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
WO2005000237A2 (en) * 2003-06-25 2005-01-06 University Of Tennessee Research Foundation Granules containing biologically active substances
PT1804772E (pt) * 2004-08-12 2011-12-02 Reckitt Benckiser Healthcare Grânulos que compreendem um fármaco anti-inflamatório não esteróide e um álcool de açúcar feito por extrusão de fundido
GB0423103D0 (en) * 2004-10-19 2004-11-17 Boots Healthcare Int Ltd Therapeutic agents

Also Published As

Publication number Publication date
EP2851068A3 (en) 2015-05-27
PL1926477T3 (pl) 2017-09-29
GB0519350D0 (en) 2005-11-02
PL2851068T3 (pl) 2020-04-30
KR101434906B1 (ko) 2014-08-27
EP2851068B1 (en) 2019-10-23
EP2851068A2 (en) 2015-03-25
EP1926477A1 (en) 2008-06-04
CN101267807A (zh) 2008-09-17
KR20130141728A (ko) 2013-12-26
AU2006293798A1 (en) 2007-03-29
KR20080047437A (ko) 2008-05-28
SG149080A1 (en) 2009-01-29
RU2438656C2 (ru) 2012-01-10
RU2008115507A (ru) 2009-10-27
WO2007034135A1 (en) 2007-03-29
CA2623281A1 (en) 2007-03-29
EP1926477B1 (en) 2017-04-19
JP2009508916A (ja) 2009-03-05
US20090142392A1 (en) 2009-06-04
AU2006293798B2 (en) 2012-08-16
CN101267807B (zh) 2013-04-10

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