ZA200802382B - Substituted cycloalkene derivative - Google Patents

Substituted cycloalkene derivative

Info

Publication number
ZA200802382B
ZA200802382B ZA200802382A ZA200802382A ZA200802382B ZA 200802382 B ZA200802382 B ZA 200802382B ZA 200802382 A ZA200802382 A ZA 200802382A ZA 200802382 A ZA200802382 A ZA 200802382A ZA 200802382 B ZA200802382 B ZA 200802382B
Authority
ZA
South Africa
Prior art keywords
substituted cycloalkene
cycloalkene derivative
derivative
substituted
cycloalkene
Prior art date
Application number
ZA200802382A
Other languages
English (en)
Inventor
Kimura Tomio
Nagasaki Takayoshi
Ando Osamu
Ohkawa Nobuyuki
Sugidachi Atsuhiro
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of ZA200802382B publication Critical patent/ZA200802382B/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/14Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/36Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/081,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D321/00Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02Seven-membered rings
    • C07D321/10Seven-membered rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/06Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/50Spiro compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
ZA200802382A 2005-09-14 2008-03-13 Substituted cycloalkene derivative ZA200802382B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2005267504 2005-09-14

Publications (1)

Publication Number Publication Date
ZA200802382B true ZA200802382B (en) 2009-06-24

Family

ID=37864954

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200802382A ZA200802382B (en) 2005-09-14 2008-03-13 Substituted cycloalkene derivative

Country Status (17)

Country Link
US (2) US7935835B2 (no)
EP (1) EP1935879B1 (no)
JP (1) JP4195074B2 (no)
KR (1) KR101327610B1 (no)
CN (1) CN101309900B (no)
AU (1) AU2006289921B2 (no)
BR (1) BRPI0615932A2 (no)
CA (1) CA2622694C (no)
IL (1) IL190063A (no)
MX (1) MX2008003759A (no)
MY (1) MY146284A (no)
NO (1) NO20081789L (no)
NZ (1) NZ567269A (no)
RU (1) RU2386613C2 (no)
TW (1) TWI387453B (no)
WO (1) WO2007032362A1 (no)
ZA (1) ZA200802382B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2620434B1 (en) * 2010-09-24 2017-01-04 Daiichi Sankyo Company, Limited A method of preparing crystals of a substituted cycloalkene derivative
WO2016181894A1 (ja) * 2015-05-08 2016-11-17 武田薬品工業株式会社 環状化合物
EP3294706B1 (en) 2015-05-08 2019-12-04 Takeda Pharmaceutical Company Limited Cyclic compounds
EP3511320A4 (en) 2016-09-09 2020-04-15 Takeda Pharmaceutical Company Limited CYCLIC COMPOUND

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4497954A (en) * 1983-11-15 1985-02-05 Riker Laboratories, Inc. Cyclopentanone derivatives
US5001144A (en) * 1987-12-21 1991-03-19 Rhone-Poulenc Rorer Pharmaceuticals Inc. Substituted cyclohexene derivatives as HMG-CoA reductase inhibitors
HRP940124A2 (en) * 1994-02-21 1997-10-31 Pliva Pharm & Chem Works Novel sulfonamidodioxepanes, methods of preparation, intermediates, salts and the use thereof
EP1524263A1 (en) * 1998-03-09 2005-04-20 Takeda Pharmaceutical Company Limited prodrugs containing cycloalkene derivatives
EP1158985B1 (en) 1999-01-13 2011-12-28 Bayer HealthCare LLC OMEGA-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS
JP4108260B2 (ja) 1999-08-06 2008-06-25 武田薬品工業株式会社 置換芳香環化合物、その製造法および用途
WO2001040498A1 (fr) * 1999-11-29 2001-06-07 Takeda Chemical Industries, Ltd. Procede de production de derives optiquement actifs du cyclohexene et de leurs intermediaires
EP1310248A4 (en) * 2000-08-10 2008-05-21 Takeda Pharmaceutical PHARMACEUTICAL COMPOSITION
JP2004002370A (ja) 2002-04-08 2004-01-08 Takeda Chem Ind Ltd 重症セプシス予防治療剤
EP2039681A4 (en) * 2006-07-07 2009-10-28 Takeda Pharmaceutical CYCLOALKENE DERIVATIVES, PROCESS FOR PRODUCTION OF DERIVATIVES, AND USE THEREOF

Also Published As

Publication number Publication date
EP1935879A4 (en) 2011-07-06
NO20081789L (no) 2008-06-12
JP4195074B2 (ja) 2008-12-10
WO2007032362A1 (ja) 2007-03-22
IL190063A0 (en) 2008-08-07
BRPI0615932A2 (pt) 2011-05-31
US7935835B2 (en) 2011-05-03
CN101309900B (zh) 2015-04-22
CN101309900A (zh) 2008-11-19
CA2622694A1 (en) 2007-03-22
RU2008114340A (ru) 2009-10-20
EP1935879B1 (en) 2016-05-11
US20090233952A1 (en) 2009-09-17
IL190063A (en) 2015-10-29
NZ567269A (en) 2010-06-25
CA2622694C (en) 2011-02-08
TW200745002A (en) 2007-12-16
MX2008003759A (es) 2008-09-12
EP1935879A1 (en) 2008-06-25
KR20080043846A (ko) 2008-05-19
RU2386613C2 (ru) 2010-04-20
MY146284A (en) 2012-07-31
JPWO2007032362A1 (ja) 2009-03-19
TWI387453B (zh) 2013-03-01
KR101327610B1 (ko) 2013-11-12
AU2006289921B2 (en) 2010-11-18
USRE43858E1 (en) 2012-12-11
AU2006289921A1 (en) 2007-03-22

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