ZA200704260B - Melanocortin receptor binding mimetibodies, compositions, methods and uses - Google Patents

Melanocortin receptor binding mimetibodies, compositions, methods and uses

Info

Publication number
ZA200704260B
ZA200704260B ZA200704260A ZA200704260A ZA200704260B ZA 200704260 B ZA200704260 B ZA 200704260B ZA 200704260 A ZA200704260 A ZA 200704260A ZA 200704260 A ZA200704260 A ZA 200704260A ZA 200704260 B ZA200704260 B ZA 200704260B
Authority
ZA
South Africa
Prior art keywords
methods
receptor binding
compositions
melanocortin receptor
mimetibodies
Prior art date
Application number
ZA200704260A
Other languages
English (en)
Inventor
Cunningham Mark
O'neil Karyn
Luo Jeffrey
Stojanovic-Susulic Vedrana
Huang Chichi
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of ZA200704260B publication Critical patent/ZA200704260B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68Melanocyte-stimulating hormone [MSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1796Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA200704260A 2004-10-25 2007-05-24 Melanocortin receptor binding mimetibodies, compositions, methods and uses ZA200704260B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62196004P 2004-10-25 2004-10-25

Publications (1)

Publication Number Publication Date
ZA200704260B true ZA200704260B (en) 2009-03-25

Family

ID=36228385

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200704260A ZA200704260B (en) 2004-10-25 2007-05-24 Melanocortin receptor binding mimetibodies, compositions, methods and uses

Country Status (29)

Country Link
US (1) US20060105951A1 (fr)
EP (1) EP1812046B1 (fr)
JP (1) JP2008517605A (fr)
KR (1) KR101255140B1 (fr)
CN (1) CN101437540B (fr)
AT (1) ATE501731T1 (fr)
AU (1) AU2005299440B2 (fr)
BR (1) BRPI0518411A2 (fr)
CA (1) CA2585287A1 (fr)
CY (1) CY1111486T1 (fr)
DE (1) DE602005026970D1 (fr)
DK (1) DK1812046T3 (fr)
EA (1) EA200700944A1 (fr)
EC (1) ECSP077416A (fr)
ES (1) ES2363023T3 (fr)
HK (1) HK1106445A1 (fr)
HR (1) HRP20110405T1 (fr)
IL (1) IL182683A0 (fr)
MA (1) MA28943B1 (fr)
ME (1) ME01234B (fr)
MX (1) MX2007004974A (fr)
NO (1) NO20072499L (fr)
PL (1) PL1812046T3 (fr)
PT (1) PT1812046E (fr)
RS (1) RS51789B (fr)
SI (1) SI1812046T1 (fr)
TN (1) TNSN07157A1 (fr)
WO (1) WO2006047535A2 (fr)
ZA (1) ZA200704260B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910101B2 (en) 2004-10-25 2011-03-22 Centocor, Inc. Melanocortin receptor binding mimetibodies, compositions, methods and uses
US7790671B2 (en) * 2005-10-07 2010-09-07 Codman & Shurtleff, Inc. Implantable pump for protein delivery for obesity control by drug infusion into the brain
WO2009151383A1 (fr) * 2008-06-09 2009-12-17 Palatin Technologies, Inc. Peptides spécifiques des récepteurs de la mélanocortine pour le traitement de l’obésité et d’autres pathologies associées à la fonction des récepteurs de la mélanocortine
WO2009152079A1 (fr) 2008-06-09 2009-12-17 Palatin Technologies, Inc. Peptides spécifiques du récepteur de mélanocortine pour le traitement d'un dysfonctionnement sexuel
US8614185B2 (en) * 2009-05-04 2013-12-24 Centocor Ortho Biotech Inc. Fusion proteins of alpha-MSH derivatives and Fc
UY32690A (es) * 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
MX2011013117A (es) 2009-06-08 2012-05-23 Palatin Technologies Inc Peptidos especificos del receptor de melanocortina.
EP2440572B1 (fr) 2009-06-08 2017-04-05 Palatin Technologies, Inc. Peptides spécifiques des récepteurs aux mélanocortines à pont lactame
WO2011063366A1 (fr) 2009-11-23 2011-05-26 Palatin Technologies, Inc. Peptides cycliques spécifiques du récepteur de la mélanocortine-1
BR112012011780A2 (pt) 2009-11-23 2019-09-24 Palatin Technologies, Inc peptídeo linear,composição farmacêutica,métodopara tratamento de umadoença,indicação,condição ou sídrome mediadsa por receptor de melanocortina emum mamífero humano ou não humano e método para tratamento de uma condição responsiva ás alterações em função de receptor de melanocortina em um mamifero humano ou não humano
JP2020141710A (ja) * 2011-07-06 2020-09-10 ゲンマブ エー/エス 抗体重鎖のc末端の修飾による補体依存性細胞傷害の調節
CN113272330B (zh) * 2019-03-02 2024-07-26 南通壹宸生物医药科技有限公司 一种双特异抗体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000033658A1 (fr) * 1998-12-09 2000-06-15 Eleanor Roosevelt Institute Composition et procedes de regulation du poids corporel et des pathologies associees
EP1303625A2 (fr) * 2000-07-14 2003-04-23 Zycos Inc. Composes en rapport avec alpha-msh et methodes d'utilisation
AU2003256336A1 (en) * 2002-06-28 2004-01-19 Centocor, Inc. Mammalian epo mimetic ch1 deleted mimetibodies, compositions, methods and uses
AU2003280130B2 (en) * 2002-06-28 2009-06-11 Centocor, Inc. Mammalian CH1 deleted mimetibodies, compositions, methods and uses
US20070135338A1 (en) * 2004-03-31 2007-06-14 Karyn O'neil Human GLP-1 mimetibodies, compositions, methods and uses

Also Published As

Publication number Publication date
WO2006047535A2 (fr) 2006-05-04
KR20070085416A (ko) 2007-08-27
EP1812046B1 (fr) 2011-03-16
EP1812046A4 (fr) 2009-11-11
CY1111486T1 (el) 2015-08-05
IL182683A0 (en) 2007-09-20
MX2007004974A (es) 2007-10-17
CN101437540B (zh) 2012-12-19
AU2005299440A1 (en) 2006-05-04
ME01234B (fr) 2013-06-20
JP2008517605A (ja) 2008-05-29
BRPI0518411A2 (pt) 2008-11-18
US20060105951A1 (en) 2006-05-18
HRP20110405T1 (hr) 2011-06-30
DE602005026970D1 (de) 2011-04-28
NO20072499L (no) 2007-07-16
EA200700944A1 (ru) 2008-04-28
PT1812046E (pt) 2011-06-28
ES2363023T3 (es) 2011-07-19
ECSP077416A (es) 2007-05-30
PL1812046T3 (pl) 2011-08-31
KR101255140B1 (ko) 2013-04-22
RS51789B (en) 2011-12-31
CN101437540A (zh) 2009-05-20
WO2006047535A3 (fr) 2008-09-04
TNSN07157A1 (en) 2008-11-21
ATE501731T1 (de) 2011-04-15
EP1812046A2 (fr) 2007-08-01
DK1812046T3 (da) 2011-06-06
AU2005299440B2 (en) 2011-12-15
HK1106445A1 (en) 2008-03-14
MA28943B1 (fr) 2007-10-01
SI1812046T1 (sl) 2011-06-30
CA2585287A1 (fr) 2006-05-04

Similar Documents

Publication Publication Date Title
TNSN07157A1 (en) Melanocortin receptor binding mimetibodies, compositions, methods and uses
WO2007014169A3 (fr) Anticorps anti-cd26 et methodes d'utilisation de ces derniers
HUS1800021I1 (hu) Humán anti-Il-23 ellenanyagok, készítmények, eljárások és alkalmazások
WO2006105338A3 (fr) Variants fc presentant des proprietes optimisees
TW200611910A (en) Interferon-alpha polypeptides and conjugates
WO2006017538A3 (fr) Proteines de liaison a la proteine hk1
MX348735B (es) Celulas madre mesenquimales que expresan los receptores tnf-alfa.
TW200631594A (en) Toll like receptor 3 antagonists, methods and uses
IL189555A0 (en) Compositions of cells enriched for combinations of various stem and progenitor cell populations, methods of use thereof and methods of private banking thereof
WO2007044083A3 (fr) Polypeptides d'interferon-alpha mis au point genetiquement
MX2010007716A (es) Combinacion de una proteina de fusion del anticuerpo-il-2 de anti-edb fibronectina y una molecula que se une a celulas b, progenitores de la celula b y/o sus contrapartes cancerigenas.
TW200745159A (en) IL-6 binding proteins
EP1617802A4 (fr) Polynucleotides specifiques de cngh0010, polypeptides, anticorps, compositions, methodes et utilisations
EP1788649A4 (fr) Liant pour pile à combustible, composition pour formation d'électrode, électrode et pile à combustible utilisant l'électrode
TW200720333A (en) Composite materials and methods of making the same
TW200711846A (en) Composite materials and methods of making the same
WO2007056760A3 (fr) Recepteurs des lymphocytes t reactifs au virus de l'hepatite c
EP1828237A4 (fr) Gene suppresseur du cancer humain, proteine codee dans ce gene, vecteur d'expression contenant ce gene et cellule transformee par ce vecteur
SG158098A1 (en) Toll like receptor 3 antagonists, methods and uses
EP1844065A4 (fr) Polypeptide possédant une fonction liée à la biosynthèse de la pyridoxine, polynucléotide codant pour ce polypeptide et leurs applications
WO2005026207A3 (fr) Proteine zacrp12 provenant des adipocytes et en relation avec le complement