ZA200702097B - Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates - Google Patents

Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates

Info

Publication number
ZA200702097B
ZA200702097B ZA200702097A ZA200702097A ZA200702097B ZA 200702097 B ZA200702097 B ZA 200702097B ZA 200702097 A ZA200702097 A ZA 200702097A ZA 200702097 A ZA200702097 A ZA 200702097A ZA 200702097 B ZA200702097 B ZA 200702097B
Authority
ZA
South Africa
Prior art keywords
racemates
enantiomers
preparation
amidoacetonitrile compounds
amidoacetonitrile
Prior art date
Application number
ZA200702097A
Other languages
English (en)
Inventor
Ducray Pierre
Gauvry Noelle
Goebel Thomas
Pautrat Francois
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200702097B publication Critical patent/ZA200702097B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/25—Aminoacetonitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
ZA200702097A 2004-11-09 2007-03-12 Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates ZA200702097B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04026510 2004-11-09

Publications (1)

Publication Number Publication Date
ZA200702097B true ZA200702097B (en) 2008-10-29

Family

ID=34927294

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200702097A ZA200702097B (en) 2004-11-09 2007-03-12 Process for the preparation of enantiomers of amidoacetonitrile compounds from their racemates

Country Status (17)

Country Link
US (1) US7485751B2 (xx)
EP (1) EP1812385B1 (xx)
JP (1) JP5112074B2 (xx)
KR (1) KR20070084061A (xx)
CN (1) CN101056849B (xx)
AR (1) AR051761A1 (xx)
AU (1) AU2005303993B2 (xx)
BR (1) BRPI0517970B1 (xx)
CA (1) CA2580247C (xx)
DK (1) DK1812385T3 (xx)
ES (1) ES2388869T3 (xx)
MX (1) MX2007005548A (xx)
NZ (1) NZ553887A (xx)
RU (1) RU2408574C2 (xx)
TW (1) TW200628439A (xx)
WO (1) WO2006050887A1 (xx)
ZA (1) ZA200702097B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0402677D0 (en) 2003-11-06 2004-03-10 Novartis Ag Organic compounds
RS60858B1 (sr) * 2007-05-15 2020-10-30 Boehringer Ingelheim Animal Health Usa Inc Ariloazol-2-il cijanoetilamino jedinjenja, postupci dobijanja i postupci njihove primene
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
WO2010048191A1 (en) 2008-10-21 2010-04-29 Merial Limited Thioamide compounds, method of making and method of using thereof
AU2009313920B2 (en) 2008-11-14 2014-10-23 Boehringer Ingelheim Animal Health USA Inc. Enantiomerically enriched aryloazol- 2 -yl cyanoethylamino paraciticidal compounds
EP2373162B1 (en) 2008-12-03 2013-08-14 Novartis AG Amidoacetonitrile compounds and pesticidal composition thereof
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
UY32992A (es) * 2009-11-23 2011-04-29 Novartis Ag Compuestos orgánicos
UY33282A (es) 2010-03-25 2011-09-30 Novartis Ag Composiciones endoparasiticidas
CN105496999A (zh) * 2012-08-06 2016-04-20 皮特尼制药股份有限公司 治疗mTOR通路相关的疾病的化合物
US8822689B2 (en) 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
WO2014090918A1 (en) 2012-12-13 2014-06-19 Novartis Ag Process for the enantiomeric enrichment of diaryloxazoline derivatives
CN103030575B (zh) * 2013-01-04 2014-10-01 中国农业大学 一类双氰基酰胺化合物及其合成方法与应用
AU2016224395A1 (en) 2015-02-24 2017-08-31 Pitney Pharmaceuticals Pty Limited Anti cancer agent comprising aminoacetonitrile compound as active ingredient

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1062334A (en) * 1963-09-19 1967-03-22 Merck & Co Inc Racemization of compounds containing an asymmetric quaternary carbon atom
DE3814887C1 (xx) * 1988-05-02 1989-09-21 Medice Chem.-Pharm. Fabrik Puetter Gmbh & Co Kg, 5860 Iserlohn, De
JPH05215736A (ja) * 1992-02-04 1993-08-24 Daicel Chem Ind Ltd クロマト分離法
US6239077B1 (en) * 1998-05-01 2001-05-29 Nihon Nohyaku Co., Ltd. Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof
JP4234885B2 (ja) 2000-07-07 2009-03-04 日本航空電子工業株式会社 サニヤック干渉計型電流センサ
US7700656B2 (en) * 2000-12-20 2010-04-20 Novartis Ag Organic compounds
TW200400932A (en) * 2002-06-19 2004-01-16 Novartis Ag Organic compounds
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
AR046757A1 (es) * 2003-12-10 2005-12-21 Novartis Ag Amidoacetonitrilos utiles como pesticidas

Also Published As

Publication number Publication date
KR20070084061A (ko) 2007-08-24
CA2580247A1 (en) 2006-05-18
RU2007121502A (ru) 2008-12-20
AR051761A1 (es) 2007-02-07
MX2007005548A (es) 2007-05-21
RU2408574C2 (ru) 2011-01-10
EP1812385B1 (en) 2012-07-18
EP1812385A1 (en) 2007-08-01
DK1812385T3 (da) 2012-10-15
AU2005303993A1 (en) 2006-05-18
JP5112074B2 (ja) 2013-01-09
CA2580247C (en) 2014-06-17
AU2005303993B2 (en) 2009-10-29
TW200628439A (en) 2006-08-16
BRPI0517970B1 (pt) 2017-01-31
ES2388869T3 (es) 2012-10-19
NZ553887A (en) 2010-09-30
JP2008518997A (ja) 2008-06-05
US7485751B2 (en) 2009-02-03
WO2006050887A1 (en) 2006-05-18
CN101056849B (zh) 2012-10-17
US20080045601A1 (en) 2008-02-21
BRPI0517970A (pt) 2008-10-21
CN101056849A (zh) 2007-10-17

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