ZA200700685B - Novel piperidine derivative for the treatment of depression - Google Patents

Novel piperidine derivative for the treatment of depression

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Publication number
ZA200700685B
ZA200700685B ZA200700685A ZA200700685A ZA200700685B ZA 200700685 B ZA200700685 B ZA 200700685B ZA 200700685 A ZA200700685 A ZA 200700685A ZA 200700685 A ZA200700685 A ZA 200700685A ZA 200700685 B ZA200700685 B ZA 200700685B
Authority
ZA
South Africa
Prior art keywords
depression
treatment
piperidine derivative
novel piperidine
novel
Prior art date
Application number
ZA200700685A
Other languages
English (en)
Inventor
Folmer James
Hamley Peter
Hunt Simon Fraser
Wesolowski Steven
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200700685B publication Critical patent/ZA200700685B/xx

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    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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ZA200700685A 2004-08-02 2007-01-24 Novel piperidine derivative for the treatment of depression ZA200700685B (en)

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DE102006060598A1 (de) * 2006-12-21 2008-06-26 Merck Patent Gmbh Tetrahydrobenzoisoxazole
SK542007A3 (sk) * 2007-04-20 2008-11-06 Unimed Pharma, Spol. S R. O. Substituované sulfónamidy, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie
HUP0900281A2 (hu) * 2009-05-05 2011-01-28 Univ Szegedi Kinurénsav-származékok, eljárás a vegyületek elõállítására, a vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk fejfájás kezelésére
KR101661825B1 (ko) * 2011-08-03 2016-09-30 내셔널 타이완 유니버시티 Ｓｒｃ 상동성-2 함유 단백질 티로신 포스파타제-1의 작용물질 및 그를 사용한 치료방법
CN103254127B (zh) * 2013-05-28 2015-08-19 北京哈三联科技有限责任公司 甘氨酸重摄取抑制剂及其应用
US9745292B2 (en) 2014-03-13 2017-08-29 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for increasing CFTR activity
EP3116501A1 (en) 2014-03-13 2017-01-18 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for increasing cftr activity
WO2015161011A1 (en) * 2014-04-17 2015-10-22 Merck Sharp & Dohme Corp. Benzamide cgrp receptor antagonists
WO2015196071A1 (en) 2014-06-19 2015-12-23 Proteostasis Therapeutics, Inc. Compounds, compositions and methods of increasing cftr activity
WO2016105484A1 (en) 2014-12-23 2016-06-30 Proteostasis Therapeutics, Inc. Derivatives of 5-(hetero)arylpyrazol-3-carboxylic amide or 1-(hetero)aryltriazol-4-carboxylic amide useful for the treatment of inter alia cystic fibrosis
WO2016105468A1 (en) 2014-12-23 2016-06-30 Proteostasis Therapeutics, Inc. Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis
US10392378B2 (en) 2014-12-23 2019-08-27 Proteostasis Therapeutics, Inc. Derivatives of 5-phenyl- or 5-heteroarylathiazol-2-carboxylic amide useful for the treatment of inter alia cystic fibrosis
MA41253A (fr) 2014-12-23 2017-10-31 Proteostasis Therapeutics Inc Composés, compositions et procédés pour augmenter l'activité du cftr
WO2017019589A1 (en) 2015-07-24 2017-02-02 Proteostasis Therapeutics, Inc. Compounds, compositions and methods of increasing cftr activity
KR20180093882A (ko) 2015-10-06 2018-08-22 프로테오스타시스 테라퓨틱스, 인크. Cftr 조절용 화합물, 조성물, 및 방법
MX2018012331A (es) 2016-04-07 2019-05-23 Proteostasis Therapeutics Inc Atomos de silicona que contienen analogos de ivacaftor.
WO2017223188A1 (en) 2016-06-21 2017-12-28 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for increasing cftr activity
EP4003972A4 (en) * 2019-07-23 2023-07-12 Board of Regents, The University of Texas System BICYCLIC RECEPTOR AGONISTS

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CA2576073A1 (en) 2006-02-09
RU2007105968A (ru) 2008-09-10
MX2007001225A (es) 2007-03-23
IL180546A0 (en) 2007-06-03
AU2005267930A1 (en) 2006-02-09
BRPI0514036A (pt) 2008-05-27
KR20070038136A (ko) 2007-04-09
JP2008508351A (ja) 2008-03-21
EP1781630A1 (en) 2007-05-09
SE0401969D0 (sv) 2004-08-02
WO2006014134A1 (en) 2006-02-09
US20070191358A1 (en) 2007-08-16
CN101014581A (zh) 2007-08-08

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