HUP0900281A2 - Kinurénsav-származékok, eljárás a vegyületek elõállítására, a vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk fejfájás kezelésére - Google Patents

Kinurénsav-származékok, eljárás a vegyületek elõállítására, a vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk fejfájás kezelésére

Info

Publication number
HUP0900281A2
HUP0900281A2 HU0900281A HUP0900281A HUP0900281A2 HU P0900281 A2 HUP0900281 A2 HU P0900281A2 HU 0900281 A HU0900281 A HU 0900281A HU P0900281 A HUP0900281 A HU P0900281A HU P0900281 A2 HUP0900281 A2 HU P0900281A2
Authority
HU
Hungary
Prior art keywords
kynurenc
headache
preparation
treatment
pharmaceutical compositions
Prior art date
Application number
HU0900281A
Other languages
English (en)
Inventor
Laszlo Dr Vecsei
Erzsebet Dr Knyihar
Arpad Dr Pardutz
Janos Dr Tajti
Hedvig Varga
Enikoe Vamos
Jozsef Dr Toldi
Ferenc Dr Fueloep
Istvan Dr Szatmari
Mihaly Dr Boros
Jozsef Dr Kaszaki
Original Assignee
Univ Szegedi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Szegedi filed Critical Univ Szegedi
Priority to HU0900281A priority Critical patent/HUP0900281A2/hu
Publication of HU0900281D0 publication Critical patent/HU0900281D0/hu
Priority to PCT/HU2010/000050 priority patent/WO2010128345A1/en
Publication of HUP0900281A2 publication Critical patent/HUP0900281A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU0900281A 2009-05-05 2009-05-05 Kinurénsav-származékok, eljárás a vegyületek elõállítására, a vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk fejfájás kezelésére HUP0900281A2 (hu)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU0900281A HUP0900281A2 (hu) 2009-05-05 2009-05-05 Kinurénsav-származékok, eljárás a vegyületek elõállítására, a vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk fejfájás kezelésére
PCT/HU2010/000050 WO2010128345A1 (en) 2009-05-05 2010-05-05 Kynurenic acid analogues, pharmaceutical compositions containing same and use of said compounds for the treatment of headache

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0900281A HUP0900281A2 (hu) 2009-05-05 2009-05-05 Kinurénsav-származékok, eljárás a vegyületek elõállítására, a vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk fejfájás kezelésére

Publications (2)

Publication Number Publication Date
HU0900281D0 HU0900281D0 (en) 2009-06-29
HUP0900281A2 true HUP0900281A2 (hu) 2011-01-28

Family

ID=89988956

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0900281A HUP0900281A2 (hu) 2009-05-05 2009-05-05 Kinurénsav-származékok, eljárás a vegyületek elõállítására, a vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk fejfájás kezelésére

Country Status (2)

Country Link
HU (1) HUP0900281A2 (hu)
WO (1) WO2010128345A1 (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP1600179A2 (hu) 2016-03-04 2017-09-28 Univ Szegedi Új típusú C-3 szubsztituált kinurénsavszármazékok hatékonyabb neuroprotektív aktivitással

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1207771A (en) * 1968-03-18 1970-10-07 Warner Lambert Pharmaceutical Anti-virally active quinoline derivatives
GB1334705A (en) * 1970-06-19 1973-10-24 Ici Ltd Pharmaceutical compositions containing kynurenic acid derivatives
US4139533A (en) * 1976-08-19 1979-02-13 Bristol-Myers Company Bicyclo[2,2,1]heptane-2,3-diendo carboxylic acid imide esters of quinoline carboxylic acid
US5270309A (en) 1987-08-12 1993-12-14 Merck Sharp & Dohme Limited Kynurenic acid derivatives useful in the treatment of neurodegenerative disorders
CN100384833C (zh) * 2001-01-16 2008-04-30 阿斯特拉曾尼卡有限公司 治疗用苯并二氢吡喃化合物
JP2002326986A (ja) * 2001-02-27 2002-11-15 Tokyo Univ Of Pharmacy & Life Science グリア細胞作用性化合物及びグルタミン酸再取り込み量増強剤
SE0401969D0 (sv) * 2004-08-02 2004-08-02 Astrazeneca Ab Piperidine derivatives

Also Published As

Publication number Publication date
HU0900281D0 (en) 2009-06-29
WO2010128345A1 (en) 2010-11-11

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees