HUP1100532A2 - Substituted curcumin derivatives, process for their preparation, and pharmaceutical compositions containing them - Google Patents

Substituted curcumin derivatives, process for their preparation, and pharmaceutical compositions containing them

Info

Publication number
HUP1100532A2
HUP1100532A2 HU1100532A HUP1100532A HUP1100532A2 HU P1100532 A2 HUP1100532 A2 HU P1100532A2 HU 1100532 A HU1100532 A HU 1100532A HU P1100532 A HUP1100532 A HU P1100532A HU P1100532 A2 HUP1100532 A2 HU P1100532A2
Authority
HU
Hungary
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
curcumin derivatives
substituted
Prior art date
Application number
HU1100532A
Other languages
Hungarian (hu)
Inventor
Mario Gyuris
Laszlo Dr Puskas
Ivan Dr Kanizsai
Bela Dr Ozsvari
Laszlo Dr Hackler
Lajos Istvan Nagy
Original Assignee
Avidin Kft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avidin Kft filed Critical Avidin Kft
Priority to HU1100532A priority Critical patent/HUP1100532A2/en
Priority to PCT/HU2012/000095 priority patent/WO2013041895A1/en
Publication of HUP1100532A2 publication Critical patent/HUP1100532A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/31—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/48—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a saturated carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/49—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU1100532A 2011-09-23 2011-09-23 Substituted curcumin derivatives, process for their preparation, and pharmaceutical compositions containing them HUP1100532A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU1100532A HUP1100532A2 (en) 2011-09-23 2011-09-23 Substituted curcumin derivatives, process for their preparation, and pharmaceutical compositions containing them
PCT/HU2012/000095 WO2013041895A1 (en) 2011-09-23 2012-09-24 Novel medicinal compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU1100532A HUP1100532A2 (en) 2011-09-23 2011-09-23 Substituted curcumin derivatives, process for their preparation, and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
HUP1100532A2 true HUP1100532A2 (en) 2013-04-29

Family

ID=89990450

Family Applications (1)

Application Number Title Priority Date Filing Date
HU1100532A HUP1100532A2 (en) 2011-09-23 2011-09-23 Substituted curcumin derivatives, process for their preparation, and pharmaceutical compositions containing them

Country Status (2)

Country Link
HU (1) HUP1100532A2 (en)
WO (1) WO2013041895A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2940470C (en) * 2015-09-18 2019-08-20 Signpath Pharma Inc. Treatment for glioblastoma
CN109734620B (en) * 2018-12-25 2021-04-20 大连理工大学 Preparation method of N-1, 5-diaryl-4-pentene-1-acetamide compound
JP2020117489A (en) * 2019-01-04 2020-08-06 アリアンツ ファーマサイエンス リミテッド Method for treating brain cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3819455A1 (en) * 1988-06-08 1989-12-14 Basf Ag 2 - ((METH) ACRYLAMIDOMETHYL) -1,3-DIKETONE
US20060276536A1 (en) 2004-02-12 2006-12-07 Vander Jagt David L Cancer treatment using curcumin derivatives
WO2007143635A1 (en) 2006-06-05 2007-12-13 Kim Darrick S Method to prepare pure curcumin
EP2993165B1 (en) 2007-01-08 2018-06-27 Allianz Pharmascience Ltd Compounds with (substituted phenyl)-propenal moiety, their derivatives, biological activity, and use thereof
WO2009017874A2 (en) 2007-05-25 2009-02-05 University Of Rochester Novel curcumin derivatives and their pharmaceutical uses thereof
WO2010033692A1 (en) 2008-09-17 2010-03-25 University Of Wyoming Curcumin-containing polymers and water soluble curcumin derivatives as prodrugs or prodrug carriers

Also Published As

Publication number Publication date
WO2013041895A1 (en) 2013-03-28

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees