ZA200700156B - Heterocyclic derivatives for treatment of hyperlipidema and related diseases - Google Patents
Heterocyclic derivatives for treatment of hyperlipidema and related diseases Download PDFInfo
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- ZA200700156B ZA200700156B ZA200700156A ZA200700156A ZA200700156B ZA 200700156 B ZA200700156 B ZA 200700156B ZA 200700156 A ZA200700156 A ZA 200700156A ZA 200700156 A ZA200700156 A ZA 200700156A ZA 200700156 B ZA200700156 B ZA 200700156B
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- cholesterol
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (1)
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| US57822704P | 2004-06-09 | 2004-06-09 |
Publications (1)
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| ZA200700156A ZA200700156B (en) | 2004-06-09 | 2007-01-05 | Heterocyclic derivatives for treatment of hyperlipidema and related diseases |
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| EP (1) | EP1753724A1 (es) |
| JP (1) | JP2008502736A (es) |
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| CN (1) | CN1968928A (es) |
| AR (1) | AR049216A1 (es) |
| AU (1) | AU2005255011A1 (es) |
| BR (1) | BRPI0511822A (es) |
| CA (1) | CA2568394A1 (es) |
| IL (1) | IL179210A0 (es) |
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| PE (1) | PE20050986A1 (es) |
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| UY (1) | UY28953A1 (es) |
| WO (1) | WO2005123686A1 (es) |
| ZA (1) | ZA200700156B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI243197B (en) * | 2001-03-08 | 2005-11-11 | Univ Hong Kong | Organometallic light-emitting material |
| TW200603795A (en) * | 2004-06-09 | 2006-02-01 | Avanir Pharmaceuticals | Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia |
| EP1847531A4 (en) * | 2005-02-09 | 2009-04-22 | Takeda Pharmaceutical | PYRAZOLE DERIVATIVE |
| GB0619611D0 (en) * | 2006-10-04 | 2006-11-15 | Ark Therapeutics Ltd | Compounds and their use |
| DE102009036604A1 (de) | 2009-07-30 | 2011-02-03 | Aicuris Gmbh & Co. Kg | Substituierte Bis-Arylpyrazolamide mit terminaler primärer Amidfunktionalisierung und ihre Verwendung |
| SG10201507846YA (en) | 2010-04-02 | 2015-10-29 | Senomyx Inc | Sweet flavor modifier |
| MY179876A (en) | 2011-08-12 | 2020-11-18 | Firmenich Incorporated | Sweet flavor modifier |
| CN103497151B (zh) * | 2013-10-30 | 2015-07-15 | 山东铂源药业有限公司 | 一种4-氨基-6-甲基烟酸的合成方法 |
| WO2016073251A1 (en) | 2014-11-07 | 2016-05-12 | Senomyx, Inc. | Substituted 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acids as sweet flavor modifiers |
| CN106187887B (zh) * | 2016-07-01 | 2018-08-14 | 上海工程技术大学 | 4-羟基喹啉-3-甲酸的制备方法 |
| WO2018035246A1 (en) * | 2016-08-16 | 2018-02-22 | Uwm Research Foundation, Inc. | Gaba(a) receptor modulators and methods to control airway hyperresponsiveness and inflammation in asthma |
| CN108623561A (zh) * | 2017-03-24 | 2018-10-09 | 中国海洋大学 | 一种制备哌尼诺酸化合物的方法 |
| CN108456154A (zh) * | 2018-04-13 | 2018-08-28 | 昆明理工大学 | 一种n-叔丁氧羰基烃基胍的制备方法 |
| EA202191890A1 (ru) * | 2019-01-18 | 2022-02-03 | Астразенека Аб | Ингибиторы pcsk9 и способы их применения |
| MX2021008533A (es) * | 2019-01-18 | 2021-08-19 | Astrazeneca Ab | Inhibidores de la pcsk9 y metodos de uso de los mismos. |
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| US3930024A (en) * | 1969-09-02 | 1975-12-30 | Parke Davis & Co | Pharmaceutical compositions and methods |
| US3773946A (en) * | 1969-09-02 | 1973-11-20 | Parke Davis & Co | Triglyceride-lowering compositions and methods |
| JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| IL64542A0 (en) * | 1981-12-15 | 1982-03-31 | Yissum Res Dev Co | Long-chain alpha,omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them |
| JPS60136512A (ja) * | 1983-12-26 | 1985-07-20 | Eisai Co Ltd | 脂質代謝改善剤 |
| DE3423166A1 (de) * | 1984-06-22 | 1986-01-02 | Epis S.A., Zug | Alpha-, omega-dicarbonsaeuren, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
| US5648387A (en) * | 1995-03-24 | 1997-07-15 | Warner-Lambert Company | Carboxyalkylethers, formulations, and treatment of vascular diseases |
| JPH10316641A (ja) * | 1997-03-14 | 1998-12-02 | Sankyo Co Ltd | カルボン酸誘導体 |
| AU8334298A (en) * | 1997-07-15 | 1999-02-10 | Novo Nordisk A/S | Nociceptin analogues |
| US6004925A (en) * | 1997-09-29 | 1999-12-21 | J. L. Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| BR0009520A (pt) * | 1999-04-01 | 2002-06-11 | Esperion Therapeutics Inc | Composto, método para sintetizar o mesmo, composição, metódos para o tratramento ou prevenção, em um paciente, de doença cardiovascular, dislipidemia, dislipoproteinemia, distúrbio de metabolismo de glucose, doença de alzheimer, sìndrome x ou sìndrome metabólica, septicemia, distúrbio trombótico, distúrbio associado com receptor ativado por proliferador de peroxissoma, obesidade, pancreatite, hipertensão, doença renal, câncer, inflamação, impotência, para reduzir o teor de gordura de carne de gado bovino, e, para reduzir o teor de colesterol de ovos de aves |
| US6664230B1 (en) * | 2000-08-24 | 2003-12-16 | The Regents Of The University Of California | Orally administered peptides to ameliorate atherosclerosis |
| US7148197B2 (en) * | 2000-08-24 | 2006-12-12 | The Regents Of The University Of California | Orally administered small peptides synergize statin activity |
| FR2820435B1 (fr) * | 2001-02-05 | 2004-02-27 | Genfit S A | Procedes d'identification de composes modulant le transport inverse du cholesterol |
| US20040248950A1 (en) * | 2001-08-24 | 2004-12-09 | Natsuki Ishizuka | Apo ai expression accelerating agent |
| US7429593B2 (en) * | 2001-09-14 | 2008-09-30 | Shionogi & Co., Ltd. | Utilities of amide compounds |
| WO2004094471A2 (en) * | 2003-04-22 | 2004-11-04 | Avanir Pharmaceuticals | Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia |
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2005
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- 2005-06-09 UY UY28953A patent/UY28953A1/es not_active Application Discontinuation
- 2005-06-09 AU AU2005255011A patent/AU2005255011A1/en not_active Abandoned
- 2005-06-09 MX MXJL06000069A patent/MXJL06000069A/es not_active Application Discontinuation
- 2005-06-09 JP JP2007527787A patent/JP2008502736A/ja not_active Withdrawn
- 2005-06-09 KR KR1020067026459A patent/KR20070026598A/ko not_active Application Discontinuation
- 2005-06-09 US US11/149,067 patent/US20060009487A1/en not_active Abandoned
- 2005-06-09 BR BRPI0511822-0A patent/BRPI0511822A/pt not_active Application Discontinuation
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- 2005-06-09 CN CNA2005800191718A patent/CN1968928A/zh active Pending
- 2005-06-09 TW TW094118999A patent/TW200602042A/zh unknown
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2006
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2007
- 2007-01-05 ZA ZA200700156A patent/ZA200700156B/en unknown
- 2007-01-08 NO NO20070139A patent/NO20070139L/no not_active Application Discontinuation
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| TW200602042A (en) | 2006-01-16 |
| KR20070026598A (ko) | 2007-03-08 |
| NO20070139L (no) | 2007-03-08 |
| AU2005255011A1 (en) | 2005-12-29 |
| PE20050986A1 (es) | 2006-02-03 |
| WO2005123686A1 (en) | 2005-12-29 |
| CN1968928A (zh) | 2007-05-23 |
| BRPI0511822A (pt) | 2007-12-26 |
| RU2006145961A (ru) | 2008-07-20 |
| EP1753724A1 (en) | 2007-02-21 |
| UY28953A1 (es) | 2006-01-31 |
| US20060009487A1 (en) | 2006-01-12 |
| JP2008502736A (ja) | 2008-01-31 |
| CA2568394A1 (en) | 2005-12-29 |
| IL179210A0 (en) | 2007-03-08 |
| AR049216A1 (es) | 2006-07-05 |
| MXJL06000069A (es) | 2007-04-10 |
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