ZA200609635B - Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers - Google Patents
Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancersInfo
- Publication number
- ZA200609635B ZA200609635B ZA200609635A ZA200609635A ZA200609635B ZA 200609635 B ZA200609635 B ZA 200609635B ZA 200609635 A ZA200609635 A ZA 200609635A ZA 200609635 A ZA200609635 A ZA 200609635A ZA 200609635 B ZA200609635 B ZA 200609635B
- Authority
- ZA
- South Africa
- Prior art keywords
- treatment
- liver diseases
- epithelial cancers
- mitochondrially targeted
- targeted antioxidants
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04103318 | 2004-07-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200609635B true ZA200609635B (en) | 2008-08-27 |
Family
ID=34929318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200609635A ZA200609635B (en) | 2004-07-13 | 2006-11-20 | Mitochondrially targeted antioxidants in the treatment of liver diseases and epithelial cancers |
Country Status (11)
Country | Link |
---|---|
US (1) | US20070225255A1 (zh) |
EP (1) | EP1765413A2 (zh) |
JP (1) | JP2008506667A (zh) |
CN (1) | CN1997403A (zh) |
AU (1) | AU2005261654A1 (zh) |
CA (1) | CA2573456A1 (zh) |
IL (1) | IL179738A0 (zh) |
RU (1) | RU2007105138A (zh) |
SG (1) | SG156613A1 (zh) |
WO (1) | WO2006005759A2 (zh) |
ZA (1) | ZA200609635B (zh) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA06008293A (es) | 2004-01-22 | 2007-06-11 | Univ Miami | Formulaciones topicas de coenzima q10 y metodos de uso. |
US20080032940A1 (en) * | 2006-08-07 | 2008-02-07 | Balaraman Kalyanaraman | Methods for reducing anthracycline-induced toxicity |
EP2119436A4 (en) | 2006-10-20 | 2010-03-03 | Ltd Liability Company Mitotech | PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF EYE DISEASES |
EA200900583A1 (ru) | 2006-10-20 | 2009-08-28 | Общество С Ограниченной Ответственностью "Митотехнология" | Композиция для регенерации, стимуляции роста и адаптации растений к различным стрессовым факторам |
US9427444B2 (en) | 2007-01-29 | 2016-08-30 | Mitotech Sa | Pharmaceutical and cosmetic compositions for accelerated healing of wounds and other surface damages |
US8349902B2 (en) * | 2007-01-29 | 2013-01-08 | Mitotech Sa | Pharmaceutical compositions useful for preventing and treating oncological diseases |
US9439916B2 (en) | 2007-04-11 | 2016-09-13 | Mitotech Sa | Composition for decelerating the aging in the organism and for extending the life time thereof and the use of said composition |
US8518915B2 (en) | 2007-06-29 | 2013-08-27 | Mitotech Sa | Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases |
WO2009033130A1 (en) * | 2007-09-07 | 2009-03-12 | Gencia Corporation | Mitochondrial compositions and uses thereof |
US8388936B2 (en) * | 2008-02-22 | 2013-03-05 | Mcw Research Foundation, Inc. | In vivo mitochondrial labeling using positively-charged nitroxide enhanced and gadolinium chelate enhanced magnetic resonance imaging |
US8388931B2 (en) * | 2008-02-29 | 2013-03-05 | Marcos Lopez | 99m Tc-labeled triphenylphosphonium derivative contrasting agents and molecular probes for early detection and imaging of breast tumors |
CA2721071C (en) | 2008-04-11 | 2017-10-17 | Cytotech Labs, Llc | Methods and use of inducing apoptosis in cancer cells |
WO2010056145A1 (ru) | 2008-11-12 | 2010-05-20 | Общество С Ограниченной Ответственностью "Митотехнология" | Способ умеренного повышения протонной проводимости биологических мембран при помощи митохондриально- адресованных делокализованных катионов |
AU2010236203A1 (en) * | 2009-04-17 | 2011-10-13 | Colby Pharmaceutical Company | Pharmaceutically active compositions comprising oxidative stress modulators (OSM), new chemical entities, compositions and uses |
JP6081195B2 (ja) | 2009-05-11 | 2017-02-15 | バーグ エルエルシー | エピメタボリックシフター、多次元細胞内分子、または環境影響因子を使用する腫瘍性障害の診断のための方法 |
EP2441453B1 (en) | 2009-06-10 | 2014-11-26 | Mitotech SA | Pharmaceutical composition for use in medical and veterinary ophthalmology |
BR112012011197A2 (pt) | 2009-11-13 | 2020-10-20 | Obschestvo S Ogranichennoi Otvetsvennostyu "Mitotekh" | subtâncias farmacêuticas com base em antioxidantes direcionados à mitocôndria |
CN103608323B (zh) | 2011-04-04 | 2016-08-17 | 博格有限责任公司 | 治疗中枢神经系统肿瘤的方法 |
EA031399B1 (ru) | 2011-06-03 | 2018-12-28 | Общество С Ограниченной Ответственностью "Митотех" | Изготовление и использование пероральных фармацевтических композиций на основе митохондриально-адресованных антиоксидантов |
AU2012312654B2 (en) | 2011-09-19 | 2017-04-13 | Gencia Corporation | Modified creatine compounds |
US10933032B2 (en) | 2013-04-08 | 2021-03-02 | Berg Llc | Methods for the treatment of cancer using coenzyme Q10 combination therapies |
SI2989110T1 (sl) * | 2013-04-24 | 2019-01-31 | Smart Brain s.r.o. | Derivati tamoksifena za zdravljenje neoplastičnih bolezni, predvsem z višjo stopnjo proteina HER2 |
IL276423B2 (en) | 2013-09-04 | 2024-05-01 | Berg Llc | Pharmaceutical preparations containing coenzyme Q10 for use in cancer treatment |
US10058542B1 (en) | 2014-09-12 | 2018-08-28 | Thioredoxin Systems Ab | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith |
KR101773404B1 (ko) | 2015-08-25 | 2017-08-31 | (주) 씨유스킨 | 자외선에 의한 피부 손상의 예방 또는 개선을 위한 화장료 조성물 |
CN107510848A (zh) * | 2016-06-15 | 2017-12-26 | 常州莱道斯生物医药科技有限公司 | 线粒体靶向制剂MitoPBN在防治糖尿病中的应用 |
CN108201543A (zh) * | 2016-12-19 | 2018-06-26 | 北京福纳康生物技术有限公司 | 水溶性富勒烯结构在制备治疗脂肪肝的药物中的应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9722361D0 (en) * | 1997-10-24 | 1997-12-17 | Pharma Nord Uk Ltd | Pharmaceutical formulation for treating liver disorders |
US6331532B1 (en) * | 1998-11-25 | 2001-12-18 | University Of Otago | Mitochondrially targeted antioxidants |
WO2005019232A1 (en) * | 2003-08-22 | 2005-03-03 | Antipodean Pharmaceuticals, Inc. | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
CA2354743A1 (en) * | 2001-08-07 | 2003-02-07 | University Of Otago | Mitochondrially targeted antioxidants |
NZ513547A (en) * | 2001-08-13 | 2002-09-27 | Antipodean Biotechnology Ltd | Synthesis of triphenylphosphonium quinols (e.g. mitoquinol) and/or quinones (e.g. mitoquinone) |
-
2005
- 2005-07-12 CA CA002573456A patent/CA2573456A1/en not_active Abandoned
- 2005-07-12 RU RU2007105138/15A patent/RU2007105138A/ru unknown
- 2005-07-12 EP EP05775873A patent/EP1765413A2/en not_active Withdrawn
- 2005-07-12 CN CNA2005800231931A patent/CN1997403A/zh active Pending
- 2005-07-12 WO PCT/EP2005/053338 patent/WO2006005759A2/en active Application Filing
- 2005-07-12 SG SG200906579-8A patent/SG156613A1/en unknown
- 2005-07-12 AU AU2005261654A patent/AU2005261654A1/en not_active Abandoned
- 2005-07-12 US US11/632,149 patent/US20070225255A1/en not_active Abandoned
- 2005-07-12 JP JP2007520833A patent/JP2008506667A/ja not_active Withdrawn
-
2006
- 2006-11-20 ZA ZA200609635A patent/ZA200609635B/xx unknown
- 2006-11-30 IL IL179738A patent/IL179738A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL179738A0 (en) | 2007-05-15 |
EP1765413A2 (en) | 2007-03-28 |
SG156613A1 (en) | 2009-11-26 |
CN1997403A (zh) | 2007-07-11 |
AU2005261654A1 (en) | 2006-01-19 |
WO2006005759A2 (en) | 2006-01-19 |
RU2007105138A (ru) | 2008-08-20 |
US20070225255A1 (en) | 2007-09-27 |
WO2006005759A3 (en) | 2006-05-11 |
CA2573456A1 (en) | 2006-01-19 |
JP2008506667A (ja) | 2008-03-06 |
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