ZA200608029B - Nitrogenous fused-ring derivatives, medicinal compositions containing the derivatives, and use thereof as drugs - Google Patents
Nitrogenous fused-ring derivatives, medicinal compositions containing the derivatives, and use thereof as drugsInfo
- Publication number
- ZA200608029B ZA200608029B ZA200608029A ZA200608029A ZA200608029B ZA 200608029 B ZA200608029 B ZA 200608029B ZA 200608029 A ZA200608029 A ZA 200608029A ZA 200608029 A ZA200608029 A ZA 200608029A ZA 200608029 B ZA200608029 B ZA 200608029B
- Authority
- ZA
- South Africa
- Prior art keywords
- derivatives
- drugs
- compositions containing
- medicinal compositions
- ring
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004061426 | 2004-03-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200608029B true ZA200608029B (en) | 2008-12-31 |
Family
ID=34918061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200608029A ZA200608029B (en) | 2004-03-04 | 2005-03-03 | Nitrogenous fused-ring derivatives, medicinal compositions containing the derivatives, and use thereof as drugs |
Country Status (13)
Country | Link |
---|---|
US (2) | US7375113B2 (de) |
EP (1) | EP1724278B1 (de) |
JP (1) | JP4902348B2 (de) |
KR (1) | KR101179451B1 (de) |
CN (1) | CN1950389B (de) |
AU (1) | AU2005219776B2 (de) |
BR (1) | BRPI0508243A (de) |
CA (1) | CA2557766C (de) |
ES (1) | ES2468219T3 (de) |
NZ (1) | NZ549628A (de) |
TW (1) | TWI351281B (de) |
WO (1) | WO2005085267A1 (de) |
ZA (1) | ZA200608029B (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1724278B1 (de) * | 2004-03-04 | 2014-05-07 | Kissei Pharmaceutical Co., Ltd. | Derivate mit stickstoffhaltigem kondensierten ring, medizinische zusammensetzungen, die die derivate enthalten, und deren verwendung als arzneimittel |
US8039456B2 (en) * | 2004-08-12 | 2011-10-18 | Helsinn Therapeutics (U.S.), Inc. | Method of stimulating the motility of the gastrointestinal system using ipamorelin |
CA2588963C (en) | 2004-11-18 | 2013-06-25 | Kissei Pharmaceutical Co., Ltd. | 1-substituted-3-.beta.-d-glucopyranosylated nitrogenous hetero-cyclic compounds and medicines containing the same |
TW200637869A (en) | 2005-01-28 | 2006-11-01 | Chugai Pharmaceutical Co Ltd | The spiroketal derivatives and the use as therapeutical agent for diabetes of the same |
PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
DE102006048728A1 (de) | 2006-10-16 | 2008-04-17 | Merck Patent Gmbh | 3-Amino-imidazo{1,2-a]pyridinderivate |
CL2008003653A1 (es) | 2008-01-17 | 2010-03-05 | Mitsubishi Tanabe Pharma Corp | Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica. |
ITMI20080846A1 (it) * | 2008-05-09 | 2009-11-10 | Andrea Balsari | Composti a struttura glicosidica attivi nella terapia di stati infiammatori locali e sistemici |
BRPI0918841B8 (pt) * | 2008-08-28 | 2021-05-25 | Pfizer | derivados de dioxa-biciclo[3.2.1]octano-2,3,4-triol, seus cristais, composições farmacêuticas e usos |
WO2010071865A1 (en) | 2008-12-19 | 2010-06-24 | Nuon Therapeutics, Inc. | Pharmaceutical compositions and methods for treating hyperuricemia and related disorders |
US20100160351A1 (en) * | 2008-12-19 | 2010-06-24 | Nuon Therapeutics, Inc. | Pharmaceutical compositions and methods for treating hyperuricemia and related disorders |
WO2011032175A1 (en) | 2009-09-14 | 2011-03-17 | Nuon Therapeutics, Inc. | Combination formulations of tranilast and allopurinol and methods related thereto |
EP2496583B1 (de) | 2009-11-02 | 2014-12-10 | Pfizer Inc | Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivate |
WO2011070592A2 (en) | 2009-12-09 | 2011-06-16 | Panacea Biotec Ltd. | Novel sugar derivatives |
JP2013531687A (ja) | 2010-07-16 | 2013-08-08 | パーデュー、ファーマ、リミテッド、パートナーシップ | ナトリウムチャネル遮断剤としてのピリジン化合物 |
MX2013003101A (es) | 2010-09-17 | 2013-09-26 | Purdue Pharma Lp | Compuestos de piridina y sus usos. |
CN102863417B (zh) * | 2011-07-09 | 2015-01-14 | 山东轩竹医药科技有限公司 | C-糖苷衍生物 |
US10806711B2 (en) | 2011-08-12 | 2020-10-20 | University Of Cincinnati | Method of treating acute decompensated heart failure with probenecid |
US9206127B2 (en) | 2012-03-16 | 2015-12-08 | Purdue Pharm, L.P. | Substituted pyridines as sodium channel blockers |
WO2014096941A1 (en) | 2012-12-20 | 2014-06-26 | Purdue Pharma L.P. | Cyclic sulfonamides as sodium channel blockers |
EP2968238A1 (de) | 2013-03-13 | 2016-01-20 | University of Cincinnati | Behandlung von diastolischer kardialer dysfunktion mit einem trpv2-rezeptoragonisten |
US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
EP2968375B1 (de) | 2013-03-14 | 2019-06-12 | MSD International GmbH | Verfahren zur herstellung von sglt2-inhibitoren |
US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
WO2015043473A1 (en) * | 2013-09-25 | 2015-04-02 | Sunshine Lake Pharma Co., Ltd. | Glucopyranosyl derivatives and their uses in medicine |
CA2889699C (en) * | 2013-09-27 | 2017-06-06 | Sunshine Lake Pharma Co., Ltd. | Glucopyranosyl derivatives and their uses in medicine |
US9580416B2 (en) | 2014-07-02 | 2017-02-28 | Pharmacyclics Llc | Inhibitors of Bruton's tyrosine kinase |
ES2930198T3 (es) * | 2016-10-14 | 2022-12-07 | Nimbus Lakshmi Inc | Inhibidores de TYK2 y usos de los mismos |
CN110054657B (zh) | 2018-01-18 | 2021-06-29 | 亚宝药业集团股份有限公司 | 吡喃葡萄糖取代的吡唑化合物及其制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2032171A1 (de) * | 1970-06-30 | 1972-01-13 | Agfa Gevaert AG, 5090 Leverkusen | Lichtempfindliches farbfotografisches Material |
CA2300211A1 (en) | 1997-08-27 | 1999-03-04 | Masato Iwasaki | Sustained-release oral preparation |
JP2001523704A (ja) | 1997-11-25 | 2001-11-27 | バイエル・アクチエンゲゼルシヤフト | α−グルコシダーゼ阻害剤を含んで成る持続放出性製剤 |
JP2001002567A (ja) | 1999-04-20 | 2001-01-09 | Takeda Chem Ind Ltd | 水溶性薬物を含有する徐放性製剤 |
JP4115105B2 (ja) * | 2001-07-02 | 2008-07-09 | 協和醗酵工業株式会社 | ピラゾール誘導体 |
JP2004300102A (ja) | 2003-03-31 | 2004-10-28 | Kissei Pharmaceut Co Ltd | 縮合複素環誘導体、それを含有する医薬組成物およびその医薬用途 |
WO2004113359A1 (ja) | 2003-06-20 | 2004-12-29 | Kissei Pharmaceutical Co., Ltd. | ピラゾール誘導体、それを含有する医薬組成物及びその製造中間体 |
EP1724278B1 (de) * | 2004-03-04 | 2014-05-07 | Kissei Pharmaceutical Co., Ltd. | Derivate mit stickstoffhaltigem kondensierten ring, medizinische zusammensetzungen, die die derivate enthalten, und deren verwendung als arzneimittel |
-
2005
- 2005-03-03 EP EP05720416.6A patent/EP1724278B1/de not_active Not-in-force
- 2005-03-03 WO PCT/JP2005/004145 patent/WO2005085267A1/ja active Application Filing
- 2005-03-03 KR KR1020067019604A patent/KR101179451B1/ko not_active IP Right Cessation
- 2005-03-03 US US10/591,757 patent/US7375113B2/en not_active Expired - Fee Related
- 2005-03-03 CA CA2557766A patent/CA2557766C/en not_active Expired - Fee Related
- 2005-03-03 ES ES05720416.6T patent/ES2468219T3/es active Active
- 2005-03-03 NZ NZ549628A patent/NZ549628A/en not_active IP Right Cessation
- 2005-03-03 ZA ZA200608029A patent/ZA200608029B/xx unknown
- 2005-03-03 AU AU2005219776A patent/AU2005219776B2/en not_active Ceased
- 2005-03-03 JP JP2006510802A patent/JP4902348B2/ja not_active Expired - Fee Related
- 2005-03-03 BR BRPI0508243-9A patent/BRPI0508243A/pt not_active Application Discontinuation
- 2005-03-03 CN CN2005800142872A patent/CN1950389B/zh not_active Expired - Fee Related
- 2005-03-04 TW TW094106582A patent/TWI351281B/zh not_active IP Right Cessation
-
2008
- 2008-02-15 US US12/032,411 patent/US7998975B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPWO2005085267A1 (ja) | 2008-01-17 |
US20080188426A1 (en) | 2008-08-07 |
CN1950389B (zh) | 2011-01-19 |
JP4902348B2 (ja) | 2012-03-21 |
EP1724278B1 (de) | 2014-05-07 |
WO2005085267A1 (ja) | 2005-09-15 |
KR20060129499A (ko) | 2006-12-15 |
US7375113B2 (en) | 2008-05-20 |
TWI351281B (en) | 2011-11-01 |
NZ549628A (en) | 2010-06-25 |
CA2557766C (en) | 2013-02-05 |
ES2468219T3 (es) | 2014-06-16 |
EP1724278A1 (de) | 2006-11-22 |
US20070191289A1 (en) | 2007-08-16 |
CN1950389A (zh) | 2007-04-18 |
EP1724278A4 (de) | 2012-05-02 |
BRPI0508243A (pt) | 2007-07-24 |
KR101179451B1 (ko) | 2012-09-07 |
AU2005219776B2 (en) | 2010-07-08 |
CA2557766A1 (en) | 2005-09-15 |
AU2005219776A1 (en) | 2005-09-15 |
US7998975B2 (en) | 2011-08-16 |
TW200533349A (en) | 2005-10-16 |
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