ZA200603563B - Enhanced B cell cytotoxicity of CDIM binding antibody - Google Patents

Enhanced B cell cytotoxicity of CDIM binding antibody Download PDF

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Publication number
ZA200603563B
ZA200603563B ZA200603563A ZA200603563A ZA200603563B ZA 200603563 B ZA200603563 B ZA 200603563B ZA 200603563 A ZA200603563 A ZA 200603563A ZA 200603563 A ZA200603563 A ZA 200603563A ZA 200603563 B ZA200603563 B ZA 200603563B
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South Africa
Prior art keywords
antibody
cell
cells
agent
cytotoxic
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ZA200603563A
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English (en)
Inventor
Neelima M Bhat
Nelson N H Teng
Marcia M Bieber
Martin E Sanders
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Palingen Inc The Board Of Trus
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Publication of ZA200603563B publication Critical patent/ZA200603563B/en

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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061Blood cells
    • AHUMAN NECESSITIES
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

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ZA200603563A 2003-11-05 2006-05-04 Enhanced B cell cytotoxicity of CDIM binding antibody ZA200603563B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51777503P 2003-11-05 2003-11-05

Publications (1)

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ZA200603563B true ZA200603563B (en) 2007-12-27

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ZA200603563A ZA200603563B (en) 2003-11-05 2006-05-04 Enhanced B cell cytotoxicity of CDIM binding antibody

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US (1) US20050112130A1 (fr)
EP (1) EP1682179A4 (fr)
JP (1) JP2007513072A (fr)
CN (1) CN1878568A (fr)
AU (1) AU2004288231A1 (fr)
BR (1) BRPI0416243A (fr)
CA (1) CA2542886A1 (fr)
IL (1) IL175318A0 (fr)
MX (1) MXPA06005104A (fr)
SG (1) SG148161A1 (fr)
WO (1) WO2005044998A2 (fr)
ZA (1) ZA200603563B (fr)

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CN1878568A (zh) 2006-12-13
SG148161A1 (en) 2008-12-31
IL175318A0 (en) 2006-09-05
EP1682179A2 (fr) 2006-07-26
CA2542886A1 (fr) 2005-05-19
JP2007513072A (ja) 2007-05-24
WO2005044998A2 (fr) 2005-05-19
US20050112130A1 (en) 2005-05-26
AU2004288231A1 (en) 2005-05-19
MXPA06005104A (es) 2007-01-25
BRPI0416243A (pt) 2007-01-09
EP1682179A4 (fr) 2008-09-03
WO2005044998A3 (fr) 2005-11-03

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