ZA200505258B - 3-Substituted-4-pyrimidone derivatives - Google Patents
3-Substituted-4-pyrimidone derivatives Download PDFInfo
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- ZA200505258B ZA200505258B ZA200505258A ZA200505258A ZA200505258B ZA 200505258 B ZA200505258 B ZA 200505258B ZA 200505258 A ZA200505258 A ZA 200505258A ZA 200505258 A ZA200505258 A ZA 200505258A ZA 200505258 B ZA200505258 B ZA 200505258B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrimidin
- pyridin
- dihydro
- methyl
- group
- Prior art date
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- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002383300 | 2002-12-16 | ||
| JP2002383301 | 2002-12-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200505258B true ZA200505258B (en) | 2006-09-27 |
Family
ID=32599307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200505258A ZA200505258B (en) | 2002-12-16 | 2003-12-12 | 3-Substituted-4-pyrimidone derivatives |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7683069B2 (fr) |
| EP (1) | EP1572681B1 (fr) |
| JP (1) | JP4616003B2 (fr) |
| KR (1) | KR100956052B1 (fr) |
| CN (1) | CN1726209B (fr) |
| BR (1) | BR0316785A (fr) |
| CA (1) | CA2510170C (fr) |
| EA (1) | EA009027B1 (fr) |
| MX (1) | MXPA05006394A (fr) |
| NO (1) | NO20053449L (fr) |
| NZ (1) | NZ541074A (fr) |
| WO (1) | WO2004055007A1 (fr) |
| ZA (1) | ZA200505258B (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR023052A1 (es) | 1998-09-25 | 2002-09-04 | Mitsuharu Yoshimura Milton | Derivados de pirimidona |
| WO2003037888A1 (fr) | 2001-09-21 | 2003-05-08 | Mitsubishi Pharma Corporation | Derives de 3-substitue-4-pyrimidone |
| AU2002337498B2 (en) | 2001-09-21 | 2006-08-10 | Mitsubishi Pharma Corporation | 3-substituted-4-pyrimidone derivatives |
| TWI357408B (en) | 2003-03-26 | 2012-02-01 | Mitsubishi Tanabe Pharma Corp | 3-substituted-4-pyrimidone derivatives |
| AR050865A1 (es) | 2004-09-09 | 2006-11-29 | Sanofi Aventis | Derivados de 2- morfolino-4-pirimidona |
| WO2006041405A1 (fr) * | 2004-10-15 | 2006-04-20 | Astrazeneca Ab | Amino-pyrimidones substitues et utilisation de ceux-ci |
| JP2008516945A (ja) * | 2004-10-15 | 2008-05-22 | アストラゼネカ・アクチエボラーグ | 置換されたアミノ化合物およびそれらの使用 |
| TW200813015A (en) * | 2006-03-15 | 2008-03-16 | Mitsubishi Pharma Corp | 2-(cyclic amino)-pyrimidone derivatives |
| KR20090052884A (ko) * | 2006-08-23 | 2009-05-26 | 화이자 프로덕츠 인크. | Ｇｓｋ-3 억제제로서의 피리미돈 화합물 |
| EP1992620A1 (fr) | 2007-05-16 | 2008-11-19 | Sanofi-Aventis | Dérivés de la pyrimidone d'arylamide pour le traitement des maladies neurodégénératives |
| EP1992624A1 (fr) * | 2007-05-16 | 2008-11-19 | Sanofi-Aventis | Composés de pyrimidonine d'hétéroarylamide |
| EP1992625A1 (fr) | 2007-05-16 | 2008-11-19 | Sanofi-Aventis | Composés de pyrimidonine d'arylamide |
| EP1992621A1 (fr) | 2007-05-16 | 2008-11-19 | Sanofi-Aventis | Dérivés de pyrimidone substitués d'un hétéroarylamide pour le traitement des maladies neurodégénératives |
| US9006232B2 (en) | 2009-08-13 | 2015-04-14 | Mitsubishi Tanabe Pharma Corporation | Pyrimidone derivatives |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS559099B2 (fr) | 1972-08-07 | 1980-03-07 | ||
| JPS4935633A (fr) | 1972-08-09 | 1974-04-02 | ||
| JPS5124008B2 (fr) | 1972-08-10 | 1976-07-21 | ||
| JPS4935632A (fr) | 1972-08-10 | 1974-04-02 | ||
| JPS5271481A (en) | 1975-12-10 | 1977-06-14 | Yoshitomi Pharmaceut Ind Ltd | Synthesis of pyridylpyrimidines |
| JPS52139085A (en) | 1976-05-13 | 1977-11-19 | Hokuriku Pharmaceutical | 22allylpiperazine derivative and method for its preparation |
| IN151188B (fr) * | 1978-02-13 | 1983-03-05 | Smith Kline French Lab | |
| US4507302A (en) * | 1979-03-19 | 1985-03-26 | The Upjohn Company | Method for treating arthritis with 6-aryl pyrimidine compounds |
| US4619933A (en) * | 1979-09-28 | 1986-10-28 | The Upjohn Company | 6-aryl pyrimidines for treating aplastic anemia |
| US4725600A (en) | 1984-07-13 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent |
| DE58908208D1 (de) | 1988-07-29 | 1994-09-22 | Ciba Geigy Ag | Thiouracile als Stabilisatoren für chlorhaltige Polymerisate. |
| DE69233767D1 (de) | 1991-12-06 | 2009-09-17 | Max Planck Gesellschaft | Verwendung von Protein-Kinasen zur Diagnose und Behandlung der Alzheimer-Krankheit |
| DE4206145A1 (de) | 1992-02-28 | 1993-09-02 | Basf Ag | Herbizide n-((pyrimidin-2-yl)aminocarbonyl)benzolfulfonamide |
| JP3324611B2 (ja) | 1992-07-03 | 2002-09-17 | 三菱化学株式会社 | タウ蛋白質のリン酸化方法 |
| JPH06329551A (ja) | 1993-03-22 | 1994-11-29 | Mitsubishi Kasei Corp | アルツハイマー病の予防または治療薬およびそのスクリーニング方法 |
| AU692484B2 (en) * | 1993-10-12 | 1998-06-11 | Du Pont Pharmaceuticals Company | 1N-alkyl-N-arylpyrimidinamines and derivatives thereof |
| FR2736053B1 (fr) * | 1995-06-28 | 1997-09-19 | Sanofi Sa | Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines |
| HUP0001698A3 (en) | 1996-12-05 | 2002-07-29 | Amgen Inc Thousand Oaks | Substituted pyrimidine compounds and their use |
| AU735901C (en) | 1996-12-05 | 2004-02-12 | Amgen, Inc. | Substituted pyrimidinone and pyridone compounds and methods of use |
| US6096753A (en) * | 1996-12-05 | 2000-08-01 | Amgen Inc. | Substituted pyrimidinone and pyridone compounds and methods of use |
| US6410729B1 (en) * | 1996-12-05 | 2002-06-25 | Amgen Inc. | Substituted pyrimidine compounds and methods of use |
| TW520362B (en) | 1996-12-05 | 2003-02-11 | Amgen Inc | Substituted pyrimidine compounds and pharmaceutical composition comprising same |
| ES2203937T3 (es) * | 1997-03-26 | 2004-04-16 | Taisho Pharmaceutical Co., Ltd | Derivados de 4-tetrahidropiridilpirimidina. |
| AR023052A1 (es) * | 1998-09-25 | 2002-09-04 | Mitsuharu Yoshimura Milton | Derivados de pirimidona |
| KR100521735B1 (ko) * | 2000-02-25 | 2005-10-17 | 에프. 호프만-라 로슈 아게 | 아데노신 수용체 조절인자 |
| AU2001262150A1 (en) | 2000-03-23 | 2001-10-03 | Mitsubishi Pharma Corporation | 2-(nitrogen-heterocyclic)pyrimidone derivatives |
| EP1136482A1 (fr) | 2000-03-23 | 2001-09-26 | Sanofi-Synthelabo | Dérivés de 2-amino-3-(alkyl)-pyrimidone comme inhibiteurs de GSK3bêta |
| DE60137426D1 (de) * | 2000-06-12 | 2009-03-05 | Eisai R&D Man Co Ltd | 1,2-dihydropyridinverbindungen, verfahren zu deren herstellung und deren verwendung |
| WO2003037888A1 (fr) * | 2001-09-21 | 2003-05-08 | Mitsubishi Pharma Corporation | Derives de 3-substitue-4-pyrimidone |
| AU2002337498B2 (en) * | 2001-09-21 | 2006-08-10 | Mitsubishi Pharma Corporation | 3-substituted-4-pyrimidone derivatives |
| TWI357408B (en) | 2003-03-26 | 2012-02-01 | Mitsubishi Tanabe Pharma Corp | 3-substituted-4-pyrimidone derivatives |
-
2003
- 2003-12-12 EA EA200500984A patent/EA009027B1/ru not_active IP Right Cessation
- 2003-12-12 CA CA2510170A patent/CA2510170C/fr not_active Expired - Fee Related
- 2003-12-12 EP EP03778893.2A patent/EP1572681B1/fr not_active Expired - Lifetime
- 2003-12-12 MX MXPA05006394A patent/MXPA05006394A/es active IP Right Grant
- 2003-12-12 JP JP2004560630A patent/JP4616003B2/ja not_active Expired - Fee Related
- 2003-12-12 US US10/538,766 patent/US7683069B2/en not_active Expired - Fee Related
- 2003-12-12 KR KR1020057011109A patent/KR100956052B1/ko not_active IP Right Cessation
- 2003-12-12 BR BR0316785-2A patent/BR0316785A/pt not_active IP Right Cessation
- 2003-12-12 CN CN200380106258XA patent/CN1726209B/zh not_active Expired - Fee Related
- 2003-12-12 ZA ZA200505258A patent/ZA200505258B/en unknown
- 2003-12-12 NZ NZ541074A patent/NZ541074A/en unknown
- 2003-12-12 WO PCT/JP2003/015968 patent/WO2004055007A1/fr active Application Filing
-
2005
- 2005-07-15 NO NO20053449A patent/NO20053449L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100956052B1 (ko) | 2010-05-06 |
| CA2510170C (fr) | 2011-05-24 |
| US20070142409A1 (en) | 2007-06-21 |
| JP4616003B2 (ja) | 2011-01-19 |
| CA2510170A1 (fr) | 2004-07-01 |
| EP1572681B1 (fr) | 2014-01-22 |
| US7683069B2 (en) | 2010-03-23 |
| CN1726209B (zh) | 2011-04-13 |
| EA200500984A1 (ru) | 2005-12-29 |
| BR0316785A (pt) | 2005-10-25 |
| KR20050099496A (ko) | 2005-10-13 |
| AU2003285777A1 (en) | 2004-07-09 |
| EA009027B1 (ru) | 2007-10-26 |
| EP1572681A1 (fr) | 2005-09-14 |
| JP2006510684A (ja) | 2006-03-30 |
| NZ541074A (en) | 2008-04-30 |
| MXPA05006394A (es) | 2007-04-16 |
| AU2003285777A8 (en) | 2004-07-09 |
| WO2004055007A1 (fr) | 2004-07-01 |
| CN1726209A (zh) | 2006-01-25 |
| NO20053449L (no) | 2005-07-15 |
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