ZA200403577B - Aminocetonitrile derivatives and their use for controlling parasites - Google Patents
Aminocetonitrile derivatives and their use for controlling parasites Download PDFInfo
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- ZA200403577B ZA200403577B ZA200403577A ZA200403577A ZA200403577B ZA 200403577 B ZA200403577 B ZA 200403577B ZA 200403577 A ZA200403577 A ZA 200403577A ZA 200403577 A ZA200403577 A ZA 200403577A ZA 200403577 B ZA200403577 B ZA 200403577B
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- South Africa
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- mono
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- 244000045947 parasite Species 0.000 title claims description 18
- 150000001875 compounds Chemical class 0.000 claims description 121
- 150000002367 halogens Chemical class 0.000 claims description 73
- 229910052736 halogen Inorganic materials 0.000 claims description 72
- 125000001424 substituent group Chemical group 0.000 claims description 65
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 58
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 43
- -1 phenylhydroxy- methyl Chemical class 0.000 claims description 41
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 36
- 150000003839 salts Chemical group 0.000 claims description 35
- 238000000034 method Methods 0.000 claims description 32
- 239000000203 mixture Substances 0.000 claims description 30
- 229910052739 hydrogen Inorganic materials 0.000 claims description 29
- 239000001257 hydrogen Substances 0.000 claims description 28
- 125000003545 alkoxy group Chemical group 0.000 claims description 25
- 150000002431 hydrogen Chemical class 0.000 claims description 20
- 238000006243 chemical reaction Methods 0.000 claims description 19
- 229910052799 carbon Inorganic materials 0.000 claims description 17
- 241001465754 Metazoa Species 0.000 claims description 15
- 239000004480 active ingredient Substances 0.000 claims description 15
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims description 14
- 125000000217 alkyl group Chemical group 0.000 claims description 13
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 claims description 13
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 claims description 11
- 238000002360 preparation method Methods 0.000 claims description 10
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- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 claims description 7
- 125000004448 alkyl carbonyl group Chemical group 0.000 claims description 6
- 125000005554 pyridyloxy group Chemical group 0.000 claims description 6
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 claims description 5
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- 238000000926 separation method Methods 0.000 claims description 5
- 238000002955 isolation Methods 0.000 claims description 4
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims description 3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/34—Nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
- C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH22252001 | 2001-12-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200403577B true ZA200403577B (en) | 2006-06-28 |
Family
ID=4568089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200403577A ZA200403577B (en) | 2001-12-06 | 2004-05-11 | Aminocetonitrile derivatives and their use for controlling parasites |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US7091371B2 (es) |
| EP (1) | EP1456170A1 (es) |
| JP (1) | JP2005511685A (es) |
| KR (1) | KR100648117B1 (es) |
| CN (2) | CN1274672C (es) |
| AR (1) | AR037746A1 (es) |
| AU (1) | AU2002358620B2 (es) |
| BR (1) | BR0214703A (es) |
| CA (1) | CA2466570A1 (es) |
| CO (1) | CO5590952A2 (es) |
| MX (1) | MXPA04005455A (es) |
| RU (1) | RU2293725C2 (es) |
| TW (1) | TWI261053B (es) |
| WO (1) | WO2003048112A1 (es) |
| ZA (1) | ZA200403577B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002316903B2 (en) * | 2001-05-15 | 2006-01-12 | Novartis Ag | Benzamidoacetonitriles and their use as antiparasitics |
| TW200400932A (en) * | 2002-06-19 | 2004-01-16 | Novartis Ag | Organic compounds |
| GB0402677D0 (en) * | 2003-11-06 | 2004-03-10 | Novartis Ag | Organic compounds |
| AU2004293463A1 (en) * | 2003-11-20 | 2005-06-09 | Angiotech International Ag | Implantable sensors and implantable pumps and anti-scarring agents |
| US8218748B2 (en) * | 2006-07-24 | 2012-07-10 | Hewlett-Packard Development Company, L.P. | Telephone call chaining |
| DK2639228T3 (en) | 2007-05-15 | 2016-09-12 | Merial Inc | Aryloazol-2-yl-cyanoethylaminoforbindelser, method of making and method of use thereof |
| AU2009307736B2 (en) | 2008-10-21 | 2015-02-05 | Boehringer Ingelheim Animal Health USA Inc. | Thioamide compounds, method of making and method of using thereof |
| EP2350212A4 (en) * | 2008-11-07 | 2012-05-23 | Huntsman Petrochemical Llc | POLYAMINO-ACETONITRILES, PROCESSES FOR PREPARING THEM AND USE THEREOF |
| CN102272105B (zh) * | 2008-11-14 | 2016-09-14 | 梅瑞尔公司 | 对映异构富集的芳基并唑-2-基氰基乙氨基杀寄生物化合物 |
| CN108524480A (zh) * | 2011-03-02 | 2018-09-14 | 国立大学法人东京大学 | 体内寄生虫防除剂 |
| US8710043B2 (en) | 2011-06-24 | 2014-04-29 | Amgen Inc. | TRPM8 antagonists and their use in treatments |
| AU2012272898A1 (en) | 2011-06-24 | 2013-04-11 | Amgen Inc. | TRPM8 antagonists and their use in treatments |
| US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
| US8822689B2 (en) | 2012-09-19 | 2014-09-02 | Merial Limited | Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof |
| CN110407681B (zh) * | 2019-08-12 | 2023-05-02 | 海南大学 | 一种脱氢姜酮衍生物、其制备方法及应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3457294A (en) * | 1966-04-22 | 1969-07-22 | Abbott Lab | N-(substituted-benzoyl) aminoaceto- and aminopropionitriles |
| US4515731A (en) * | 1975-08-25 | 1985-05-07 | Monsanto Company | Asymmetric catalysis |
| US5959870A (en) | 1998-02-20 | 1999-09-28 | Gamma-Metrics | Real-time optimization for mix beds |
| US6239077B1 (en) * | 1998-05-01 | 2001-05-29 | Nihon Nohyaku Co., Ltd. | Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof |
| US7700656B2 (en) | 2000-12-20 | 2010-04-20 | Novartis Ag | Organic compounds |
-
2002
- 2002-12-04 AR ARP020104691A patent/AR037746A1/es not_active Application Discontinuation
- 2002-12-04 TW TW091135142A patent/TWI261053B/zh not_active IP Right Cessation
- 2002-12-05 WO PCT/EP2002/013811 patent/WO2003048112A1/en active Application Filing
- 2002-12-05 EP EP02792909A patent/EP1456170A1/en not_active Withdrawn
- 2002-12-05 AU AU2002358620A patent/AU2002358620B2/en not_active Ceased
- 2002-12-05 CA CA002466570A patent/CA2466570A1/en not_active Abandoned
- 2002-12-05 BR BR0214703-3A patent/BR0214703A/pt not_active IP Right Cessation
- 2002-12-05 KR KR1020047008684A patent/KR100648117B1/ko not_active IP Right Cessation
- 2002-12-05 CN CNB028241673A patent/CN1274672C/zh not_active Expired - Fee Related
- 2002-12-05 MX MXPA04005455A patent/MXPA04005455A/es unknown
- 2002-12-05 JP JP2003549304A patent/JP2005511685A/ja not_active Ceased
- 2002-12-05 US US10/496,620 patent/US7091371B2/en not_active Expired - Fee Related
- 2002-12-05 RU RU2004120790/04A patent/RU2293725C2/ru not_active IP Right Cessation
-
2003
- 2003-06-18 CN CNB038172127A patent/CN1293047C/zh not_active Expired - Fee Related
-
2004
- 2004-05-11 ZA ZA200403577A patent/ZA200403577B/en unknown
- 2004-07-06 CO CO04063920A patent/CO5590952A2/es not_active Application Discontinuation
-
2006
- 2006-06-14 US US11/452,857 patent/US20060264653A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR100648117B1 (ko) | 2006-11-24 |
| CN1668580A (zh) | 2005-09-14 |
| BR0214703A (pt) | 2004-08-31 |
| CN1293047C (zh) | 2007-01-03 |
| JP2005511685A (ja) | 2005-04-28 |
| CN1274672C (zh) | 2006-09-13 |
| MXPA04005455A (es) | 2005-04-19 |
| EP1456170A1 (en) | 2004-09-15 |
| RU2293725C2 (ru) | 2007-02-20 |
| US20060264653A1 (en) | 2006-11-23 |
| US20050033081A1 (en) | 2005-02-10 |
| AU2002358620A1 (en) | 2003-06-17 |
| AU2002358620B2 (en) | 2006-08-31 |
| CA2466570A1 (en) | 2003-06-12 |
| AR037746A1 (es) | 2004-12-01 |
| CO5590952A2 (es) | 2005-12-30 |
| US7091371B2 (en) | 2006-08-15 |
| TW200300755A (en) | 2003-06-16 |
| WO2003048112A1 (en) | 2003-06-12 |
| RU2004120790A (ru) | 2005-05-27 |
| KR20050044719A (ko) | 2005-05-12 |
| TWI261053B (en) | 2006-09-01 |
| CN1599716A (zh) | 2005-03-23 |
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