ZA200402351B - Use of gp130 activators in diabetic neuropathy. - Google Patents

Use of gp130 activators in diabetic neuropathy. Download PDF

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Publication number
ZA200402351B
ZA200402351B ZA200402351A ZA200402351A ZA200402351B ZA 200402351 B ZA200402351 B ZA 200402351B ZA 200402351 A ZA200402351 A ZA 200402351A ZA 200402351 A ZA200402351 A ZA 200402351A ZA 200402351 B ZA200402351 B ZA 200402351B
Authority
ZA
South Africa
Prior art keywords
use according
stz
animals
substance
signaling
Prior art date
Application number
ZA200402351A
Other languages
English (en)
Inventor
Michel Dreano
Pierre-Alain Vitte
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of ZA200402351B publication Critical patent/ZA200402351B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/204IL-6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200402351A 2001-10-11 2004-03-25 Use of gp130 activators in diabetic neuropathy. ZA200402351B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01123400 2001-10-11

Publications (1)

Publication Number Publication Date
ZA200402351B true ZA200402351B (en) 2005-03-29

Family

ID=8178778

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200402351A ZA200402351B (en) 2001-10-11 2004-03-25 Use of gp130 activators in diabetic neuropathy.

Country Status (20)

Country Link
US (3) US7465441B2 (sh)
EP (1) EP1434597B1 (sh)
JP (1) JP2005505608A (sh)
KR (1) KR20050035151A (sh)
CN (1) CN1602203A (sh)
AT (1) ATE542542T1 (sh)
AU (1) AU2002340547B2 (sh)
BR (1) BR0213183A (sh)
CA (1) CA2463020A1 (sh)
DK (1) DK1434597T3 (sh)
EA (1) EA006881B1 (sh)
ES (1) ES2381341T3 (sh)
HR (1) HRP20040292A2 (sh)
IL (1) IL161310A0 (sh)
MX (1) MXPA04003442A (sh)
NO (1) NO20041908L (sh)
PL (1) PL369296A1 (sh)
WO (1) WO2003033015A1 (sh)
YU (1) YU29804A (sh)
ZA (1) ZA200402351B (sh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003033015A1 (en) * 2001-10-11 2003-04-24 Applied Research Systems Ars Holding N.V. USE OF gp130 ACTIVATORS IN DIABETIC NEUROPATHY
WO2004101617A1 (en) 2003-05-13 2004-11-25 Applied Research Systems Ars Holding N.V. Active variants of the il-18 binding protein and medical uses thereof
IL161672A0 (en) 2004-04-29 2004-09-27 Yeda Res & Dev Compositions and methods for therapy of chemotherapy-induced neuropathy
AU2011203356B2 (en) * 2004-04-29 2012-03-22 Yeda Research & Development Co., Ltd IL6R/IL6 chimera for therapy of chemotherapy-induced peripheral neuropathy
IL161673A0 (en) * 2004-04-29 2004-09-27 Applied Research Systems Compositions and methods for therapy of chemotherapy-induced neuropathy
IL163856A0 (en) * 2004-09-01 2005-12-18 Applied Research Systems Use of IL-6 in vascular complications
CA2681935A1 (en) * 2007-03-30 2008-10-09 Baker Medical Research Institute Treatment of obesity
DE102008057867A1 (de) * 2008-11-18 2010-05-20 B. Braun Melsungen Ag Fettemulsion zur künstlichen Ernährung von schwerkranken Intensivpatienten
CN106924736B (zh) * 2017-05-09 2020-01-03 北京师范大学 gp130抑制剂在制备干预和治疗肥胖导致的血糖代谢疾病产品中的应用
FR3080533A1 (fr) * 2018-04-27 2019-11-01 Enterosys Utilisation de l'il-6 pour le traitement du diabete

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849571A (en) * 1990-10-10 1998-12-15 University Of Pittsburgh Of The Commonwealth System Of Higher Education Latency active herpes virus promoters and their use
US5300292A (en) * 1991-05-03 1994-04-05 The Regents Of The University Of California Composition and method for treating inflammation
IT1261787B (it) * 1993-06-23 1996-06-03 Angeletti P Ist Richerche Bio Metodologia per la selezione di superagonisti, antagonisti e super- antagonisti di ormoni del cui complesso recettoriale fa parte gp 130.
US6479258B1 (en) * 1995-12-07 2002-11-12 Diversa Corporation Non-stochastic generation of genetic vaccines
US5741772A (en) * 1997-02-03 1998-04-21 Amgen Inc. Neurotrophic factor NNT-1
WO2001003737A1 (en) 1999-07-13 2001-01-18 Bolder Biotechnology Inc. Immunoglobulin fusion proteins
WO2003033015A1 (en) * 2001-10-11 2003-04-24 Applied Research Systems Ars Holding N.V. USE OF gp130 ACTIVATORS IN DIABETIC NEUROPATHY

Also Published As

Publication number Publication date
WO2003033015A1 (en) 2003-04-24
JP2005505608A (ja) 2005-02-24
DK1434597T3 (da) 2012-02-27
BR0213183A (pt) 2004-08-31
NO20041908L (no) 2004-05-10
US20050058623A1 (en) 2005-03-17
US7465441B2 (en) 2008-12-16
MXPA04003442A (es) 2004-07-08
EA200400520A1 (ru) 2004-08-26
HRP20040292A2 (en) 2005-06-30
EP1434597A1 (en) 2004-07-07
CA2463020A1 (en) 2003-04-24
ATE542542T1 (de) 2012-02-15
CN1602203A (zh) 2005-03-30
AU2002340547B2 (en) 2008-04-03
US8278286B2 (en) 2012-10-02
PL369296A1 (en) 2005-04-18
YU29804A (sh) 2006-08-17
KR20050035151A (ko) 2005-04-15
IL161310A0 (en) 2004-09-27
US20100189684A1 (en) 2010-07-29
EA006881B1 (ru) 2006-04-28
ES2381341T3 (es) 2012-05-25
EP1434597B1 (en) 2012-01-25
US20090169506A1 (en) 2009-07-02

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