ZA200401725B - Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]-fluorene-6-carboxylic acid derivatives serving as NMDA antagonists. - Google Patents

Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]-fluorene-6-carboxylic acid derivatives serving as NMDA antagonists. Download PDF

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Publication number
ZA200401725B
ZA200401725B ZA200401725A ZA200401725A ZA200401725B ZA 200401725 B ZA200401725 B ZA 200401725B ZA 200401725 A ZA200401725 A ZA 200401725A ZA 200401725 A ZA200401725 A ZA 200401725A ZA 200401725 B ZA200401725 B ZA 200401725B
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ZA
South Africa
Prior art keywords
polysubstituted
unsubstituted
mono
benzo
aza
Prior art date
Application number
ZA200401725A
Other languages
English (en)
Inventor
Matthias Gerlach
Werner Guenter Englberger
Petra Bloms-Funke
Jagusch Utz-Peter
Michael Przewosny
Elke Reissmueller
Corinna Sundemann-Nee-Maul
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of ZA200401725B publication Critical patent/ZA200401725B/en

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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  • Hematology (AREA)
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ZA200401725A 2001-08-03 2004-03-02 Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]-fluorene-6-carboxylic acid derivatives serving as NMDA antagonists. ZA200401725B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10137487A DE10137487A1 (de) 2001-08-03 2001-08-03 Substituierte 5,6,6a,11b-Tetrahydro-7-oxa-6-aza- benzo[c]fluoren-6-carbonsäurederivate

Publications (1)

Publication Number Publication Date
ZA200401725B true ZA200401725B (en) 2005-01-31

Family

ID=7693857

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200401725A ZA200401725B (en) 2001-08-03 2004-03-02 Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]-fluorene-6-carboxylic acid derivatives serving as NMDA antagonists.

Country Status (21)

Country Link
US (1) US7199130B2 (pl)
EP (1) EP1412361B1 (pl)
JP (1) JP2005500374A (pl)
KR (1) KR20040020078A (pl)
CN (1) CN1697836A (pl)
AT (1) ATE402178T1 (pl)
BR (1) BR0211734A (pl)
CA (1) CA2456124A1 (pl)
CO (1) CO5550438A2 (pl)
DE (2) DE10137487A1 (pl)
EC (1) ECSP044968A (pl)
ES (1) ES2310211T3 (pl)
HU (1) HUP0400800A3 (pl)
IL (1) IL160160A0 (pl)
MX (1) MXPA04000953A (pl)
NO (1) NO20040471L (pl)
NZ (1) NZ531372A (pl)
PL (1) PL368073A1 (pl)
RU (1) RU2004106533A (pl)
WO (1) WO2003014124A1 (pl)
ZA (1) ZA200401725B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10304950A1 (de) * 2003-02-06 2004-08-19 Grünenthal GmbH Herstellung von Tetrahydrochinolinbenzofuranen
KR20050021629A (ko) * 2003-08-25 2005-03-07 학교법인 이화학당 신규한 벤조플루오렌 디온계 화합물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0386839B1 (en) * 1989-03-08 1997-01-15 Merck Sharp & Dohme Ltd. Tetrahydroquinoline derivatives useful for neurodegenerative disorders
DE19536809A1 (de) * 1995-10-02 1997-04-03 Basf Ag Heterocyclisch substituierte Salicylsäurederivate
US5925527A (en) * 1997-02-04 1999-07-20 Trega Biosciences, Inc. Tricyclic Tetrahydroquinoline derivatives and tricyclic tetrahydroquinoline combinatorial libraries
GB9706294D0 (en) * 1997-03-26 1997-05-14 Glaxo Wellcome Spa Heterocyclic compound
MY125037A (en) * 1998-06-10 2006-07-31 Glaxo Wellcome Spa 1,2,3,4 tetrahydroquinoline derivatives
DE10005302A1 (de) * 2000-02-07 2002-01-17 Gruenenthal Gmbh Substituierte 1,2,3,4-Tetrahydrochinolin-2-carbonsäurederivate

Also Published As

Publication number Publication date
ECSP044968A (es) 2004-03-23
HUP0400800A2 (hu) 2004-07-28
CA2456124A1 (en) 2003-02-20
IL160160A0 (en) 2004-07-25
MXPA04000953A (es) 2004-04-20
CN1697836A (zh) 2005-11-16
NZ531372A (en) 2005-03-24
EP1412361A1 (de) 2004-04-28
NO20040471L (no) 2004-02-02
ES2310211T3 (es) 2009-01-01
RU2004106533A (ru) 2005-07-27
WO2003014124A1 (de) 2003-02-20
JP2005500374A (ja) 2005-01-06
HUP0400800A3 (en) 2007-09-28
CO5550438A2 (es) 2005-08-31
KR20040020078A (ko) 2004-03-06
DE10137487A1 (de) 2003-03-27
DE50212538D1 (de) 2008-09-04
US20040248889A1 (en) 2004-12-09
BR0211734A (pt) 2004-09-21
ATE402178T1 (de) 2008-08-15
US7199130B2 (en) 2007-04-03
PL368073A1 (pl) 2005-03-21
EP1412361B1 (de) 2008-07-23

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