ZA200309342B - Method of tablet enrobing. - Google Patents
Method of tablet enrobing. Download PDFInfo
- Publication number
- ZA200309342B ZA200309342B ZA200309342A ZA200309342A ZA200309342B ZA 200309342 B ZA200309342 B ZA 200309342B ZA 200309342 A ZA200309342 A ZA 200309342A ZA 200309342 A ZA200309342 A ZA 200309342A ZA 200309342 B ZA200309342 B ZA 200309342B
- Authority
- ZA
- South Africa
- Prior art keywords
- tablet
- film
- vacuum
- chamber
- overlapping
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 26
- 239000000463 material Substances 0.000 claims abstract description 34
- 238000000576 coating method Methods 0.000 claims abstract description 21
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims abstract description 16
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims abstract description 16
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims abstract description 16
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims abstract description 16
- 238000007666 vacuum forming Methods 0.000 claims abstract description 11
- 239000000853 adhesive Substances 0.000 claims description 7
- 230000001070 adhesive effect Effects 0.000 claims description 7
- 239000012815 thermoplastic material Substances 0.000 claims description 3
- 239000007888 film coating Substances 0.000 claims description 2
- 238000009501 film coating Methods 0.000 claims description 2
- 239000011248 coating agent Substances 0.000 abstract description 13
- 239000003814 drug Substances 0.000 abstract description 4
- 239000003826 tablet Substances 0.000 description 64
- 108010010803 Gelatin Proteins 0.000 description 9
- 229920000159 gelatin Polymers 0.000 description 9
- 239000008273 gelatin Substances 0.000 description 9
- 235000019322 gelatine Nutrition 0.000 description 9
- 235000011852 gelatine desserts Nutrition 0.000 description 9
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 8
- 239000004014 plasticizer Substances 0.000 description 7
- 239000000203 mixture Substances 0.000 description 5
- 239000004372 Polyvinyl alcohol Substances 0.000 description 4
- 239000003292 glue Substances 0.000 description 4
- 235000014655 lactic acid Nutrition 0.000 description 4
- 239000004310 lactic acid Substances 0.000 description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- 229920001169 thermoplastic Polymers 0.000 description 3
- 239000004416 thermosoftening plastic Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 241000283690 Bos taurus Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000003856 thermoforming Methods 0.000 description 2
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 description 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 1
- 206010016276 Fear of animals Diseases 0.000 description 1
- 239000004348 Glyceryl diacetate Substances 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 229940072056 alginate Drugs 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 229940061720 alpha hydroxy acid Drugs 0.000 description 1
- 150000001280 alpha hydroxy acids Chemical class 0.000 description 1
- 201000002426 animal phobia Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 239000007894 caplet Substances 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 239000000989 food dye Substances 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 235000019443 glyceryl diacetate Nutrition 0.000 description 1
- 235000013773 glyceryl triacetate Nutrition 0.000 description 1
- 239000001087 glyceryl triacetate Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- 239000011345 viscous material Substances 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/005—Coating of tablets or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- General Preparation And Processing Of Foods (AREA)
- Saccharide Compounds (AREA)
- Glanulating (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Encapsulation Of And Coatings For Semiconductor Or Solid State Devices (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0113403.0A GB0113403D0 (en) | 2001-06-02 | 2001-06-02 | Tablet enrobing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200309342B true ZA200309342B (en) | 2004-09-27 |
Family
ID=9915755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200309342A ZA200309342B (en) | 2001-06-02 | 2003-12-01 | Method of tablet enrobing. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7744945B2 (da) |
| EP (1) | EP1392251B1 (da) |
| JP (1) | JP2004537351A (da) |
| CN (1) | CN1240376C (da) |
| AT (1) | ATE371444T1 (da) |
| AU (1) | AU2002304511B2 (da) |
| CA (1) | CA2445649A1 (da) |
| DE (1) | DE60222119T2 (da) |
| DK (1) | DK1392251T3 (da) |
| ES (1) | ES2294136T3 (da) |
| GB (1) | GB0113403D0 (da) |
| HK (1) | HK1060852A1 (da) |
| NZ (1) | NZ529170A (da) |
| PT (1) | PT1392251E (da) |
| WO (1) | WO2002098394A1 (da) |
| ZA (1) | ZA200309342B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0211620D0 (en) | 2002-05-21 | 2002-07-03 | Bioprogress Technology Ltd | Powder compaction and enrobing |
| GB0221986D0 (en) * | 2002-09-21 | 2002-10-30 | Bioprogress Technology Ltd | Films with improved barrier properties |
| GB2401091A (en) * | 2003-05-02 | 2004-11-03 | Reckitt Benckiser | Packaging of compacted particulate compositions |
| GB0322358D0 (en) | 2003-09-24 | 2003-10-22 | Bioprogress Technology Ltd | Improvements in powder compaction and enrobing |
| US20070281007A1 (en) * | 2004-08-27 | 2007-12-06 | Jacob Jules S | Mucoadhesive Oral Formulations of High Permeability, High Solubility Drugs |
| US20060045865A1 (en) * | 2004-08-27 | 2006-03-02 | Spherics, Inc. | Controlled regional oral delivery |
| EP1944008A3 (en) * | 2004-09-24 | 2008-07-23 | BioProgress Technology Limited | Additional improvements in powder compaction and enrobing |
| CN101065091A (zh) * | 2004-09-24 | 2007-10-31 | 生物进展技术有限公司 | 对粉末压实和包覆的额外改进 |
| DE102005020852A1 (de) * | 2005-05-02 | 2006-11-09 | Robert Bürkle GmbH | Verfahren zur Beschichtung von Werkstücken |
| GB0522186D0 (en) * | 2005-10-31 | 2005-12-07 | Bioprogress Technology Ltd | Sealed tablet |
| GB0522188D0 (en) * | 2005-10-31 | 2005-12-07 | Bioprogress Technology Ltd | Apparatus for tablet coating |
| CN102648959A (zh) * | 2012-04-28 | 2012-08-29 | 十堰市神农蜂语生物科技有限公司 | 蜂王浆肠溶制剂及其制备方法 |
| US10184097B2 (en) * | 2013-02-08 | 2019-01-22 | Ecolab Usa Inc. | Protective coatings for detersive agents and methods of forming and detecting the same |
| JP5651263B1 (ja) * | 2014-05-02 | 2015-01-07 | 株式会社浅野研究所 | 熱板加熱による熱成形装置 |
| JPWO2018074261A1 (ja) * | 2016-10-17 | 2019-08-22 | 第一三共株式会社 | 封入容器の製造方法及び製造装置 |
| JP2020018326A (ja) * | 2016-10-17 | 2020-02-06 | 株式会社菊水製作所 | 製剤の製造方法及び製造装置 |
| CN107773426B (zh) * | 2017-11-22 | 2020-03-27 | 青岛大学附属医院 | 西药片裹膜装置 |
| JP2023534162A (ja) * | 2020-07-10 | 2023-08-08 | コテックス テクノロジーズ インコーポレイテッド | コーティングされた基材及びその製造方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5228926A (en) * | 1975-08-27 | 1977-03-04 | Furointo Sangyo Kk | Process for film coating of medicines |
| US4275544A (en) * | 1977-09-05 | 1981-06-30 | Kureha Kagaku Kogyo Kabushiki Kaisha | Vacuum packaging method |
| FR2406567A1 (fr) * | 1977-10-24 | 1979-05-18 | Dubois Jacques | Procede et dispositif destines a l'emballage etanche sous film thermoplastique et thermoformable de produits exigeant une protection absolue |
| US4365060A (en) * | 1979-04-28 | 1982-12-21 | Shin-Etsu Chemical Co. Ltd. | Enterosoluble capsules |
| US4302440B1 (en) * | 1980-07-31 | 1986-08-05 | Easily-swallowed, powder-free and gastric-disintegrable aspirin tablet thinly-coated with hydroxypropyl methylcellulose and aqueous spray-coating preparation thereof | |
| GB2145363B (en) * | 1983-08-23 | 1986-09-24 | Grace W R & Co | Vacuum skin package |
| US4928840A (en) * | 1986-02-25 | 1990-05-29 | American Home Products Corporation | Tamper proof encapsulated medicaments |
| US5234099A (en) * | 1987-02-20 | 1993-08-10 | Mcneil-Ppc, Inc. | Coated medicaments and apparatus and methods for making same |
| US5146730A (en) * | 1989-09-20 | 1992-09-15 | Banner Gelatin Products Corp. | Film-enrobed unitary-core medicament and the like |
| JPH071404A (ja) * | 1993-06-21 | 1995-01-06 | Shikoku Kogei Kk | 化粧板及び化粧板の製造方法 |
| DE4446468A1 (de) * | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von umhüllten Tabletten |
| US5682733A (en) * | 1996-05-09 | 1997-11-04 | Perrone; Aldo | Apparatus for enrobing tablets |
| US6352719B1 (en) * | 1998-11-11 | 2002-03-05 | Bioprogress Technology International, Inc. | Capsule based drug delivery system |
-
2001
- 2001-06-02 GB GBGB0113403.0A patent/GB0113403D0/en not_active Ceased
-
2002
- 2002-05-29 NZ NZ529170A patent/NZ529170A/en unknown
- 2002-05-29 EP EP02732903A patent/EP1392251B1/en not_active Expired - Lifetime
- 2002-05-29 PT PT02732903T patent/PT1392251E/pt unknown
- 2002-05-29 ES ES02732903T patent/ES2294136T3/es not_active Expired - Lifetime
- 2002-05-29 JP JP2003501434A patent/JP2004537351A/ja active Pending
- 2002-05-29 DE DE60222119T patent/DE60222119T2/de not_active Expired - Lifetime
- 2002-05-29 CN CNB028111621A patent/CN1240376C/zh not_active Expired - Fee Related
- 2002-05-29 AU AU2002304511A patent/AU2002304511B2/en not_active Ceased
- 2002-05-29 US US10/477,570 patent/US7744945B2/en not_active Expired - Fee Related
- 2002-05-29 AT AT02732903T patent/ATE371444T1/de not_active IP Right Cessation
- 2002-05-29 WO PCT/GB2002/002506 patent/WO2002098394A1/en active IP Right Grant
- 2002-05-29 DK DK02732903T patent/DK1392251T3/da active
- 2002-05-29 CA CA002445649A patent/CA2445649A1/en not_active Abandoned
-
2003
- 2003-12-01 ZA ZA200309342A patent/ZA200309342B/en unknown
-
2004
- 2004-05-31 HK HK04103888A patent/HK1060852A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1240376C (zh) | 2006-02-08 |
| GB0113403D0 (en) | 2001-07-25 |
| ES2294136T3 (es) | 2008-04-01 |
| JP2004537351A (ja) | 2004-12-16 |
| PT1392251E (pt) | 2007-11-23 |
| DE60222119T2 (de) | 2008-05-21 |
| HK1060852A1 (en) | 2004-08-27 |
| EP1392251A1 (en) | 2004-03-03 |
| US20040161527A1 (en) | 2004-08-19 |
| US7744945B2 (en) | 2010-06-29 |
| DE60222119D1 (de) | 2007-10-11 |
| WO2002098394A1 (en) | 2002-12-12 |
| CA2445649A1 (en) | 2002-12-12 |
| NZ529170A (en) | 2006-09-29 |
| ATE371444T1 (de) | 2007-09-15 |
| DK1392251T3 (da) | 2008-01-21 |
| EP1392251B1 (en) | 2007-08-29 |
| AU2002304511B2 (en) | 2007-11-15 |
| CN1520287A (zh) | 2004-08-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7744945B2 (en) | Method of tablet enrobing | |
| AU2002304511A1 (en) | Method of tablet enrobing | |
| US4154636A (en) | Method of film-coating medicines | |
| US20020026771A1 (en) | Method of encapsulation | |
| EP0210325B1 (en) | Method of film-coating hard capsules | |
| Macchi et al. | Enteric-coating of pulsatile-release HPC capsules prepared by injection molding | |
| DK0493489T3 (da) | Filmovertrukket enhedskernemedikament og lignende | |
| KR20080059472A (ko) | 분말 압착 및 피복 | |
| CN113993509A (zh) | 用胶囊填充机制备具有基于(甲基)丙烯酸酯共聚物的包衣的填充硬壳胶囊的方法 | |
| CA3137322A1 (en) | Process for preparing filled hard-shell capsules with cellulose or starch-based coatings with a capsule-filling machine | |
| EP0781541A3 (en) | Method and apparatus for manufacturing pharmaceutical cellulose capsules - sizing the capsule | |
| KR20040002385A (ko) | 풀룰란 고함유 성형물과 그 제조방법 및 그 용도 | |
| US4786504A (en) | Colored intagliated articles | |
| CN108888514B (zh) | 片剂的连续贴体包衣装置和包衣方法 | |
| WO2007052012A2 (en) | Apparatus for tablet coating | |
| AU751292B2 (en) | Improvements in or relating to encapsulation | |
| CN1972658A (zh) | 由不对称制造生产的胶囊 | |
| Schad et al. | Coating and taste masking with shellac | |
| WO2007052003A9 (en) | Sealed tablet | |
| CN106822045A (zh) | 一种右兰索拉唑缓释制剂及其制备方法与药品 |