ZA200302159B - New compounds derived from quinazoline, a process for their preparation and pharmaceutical compositions containing them. - Google Patents

New compounds derived from quinazoline, a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
ZA200302159B
ZA200302159B ZA200302159A ZA200302159A ZA200302159B ZA 200302159 B ZA200302159 B ZA 200302159B ZA 200302159 A ZA200302159 A ZA 200302159A ZA 200302159 A ZA200302159 A ZA 200302159A ZA 200302159 B ZA200302159 B ZA 200302159B
Authority
ZA
South Africa
Prior art keywords
quinazoline
preparation
pharmaceutical compositions
compositions containing
new compounds
Prior art date
Application number
ZA200302159A
Other languages
English (en)
Inventor
Solo Goldstein
Alain Dhainaut
Andre Tizot
Jean-Luc Fauchere
Nathalie Kucharczyk
John Hickman
Alain Pierre
Gordon Tucker
Laurence Kraus-Berthier
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of ZA200302159B publication Critical patent/ZA200302159B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
ZA200302159A 2002-03-18 2003-03-18 New compounds derived from quinazoline, a process for their preparation and pharmaceutical compositions containing them. ZA200302159B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0203299A FR2837201A1 (fr) 2002-03-18 2002-03-18 Nouveaux composes derives de la quinazoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA200302159B true ZA200302159B (en) 2003-09-23

Family

ID=8871501

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200302159A ZA200302159B (en) 2002-03-18 2003-03-18 New compounds derived from quinazoline, a process for their preparation and pharmaceutical compositions containing them.

Country Status (16)

Country Link
US (1) US20030199530A1 (zh)
EP (1) EP1346992A1 (zh)
JP (1) JP2003292491A (zh)
KR (1) KR20030076350A (zh)
CN (1) CN1445226A (zh)
AR (1) AR038988A1 (zh)
AU (1) AU2003201326A1 (zh)
BR (1) BR0300698A (zh)
CA (1) CA2423259A1 (zh)
EA (1) EA200300272A1 (zh)
FR (1) FR2837201A1 (zh)
MX (1) MXPA03002088A (zh)
NO (1) NO20031219L (zh)
NZ (1) NZ524771A (zh)
PL (1) PL359208A1 (zh)
ZA (1) ZA200302159B (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1621539A1 (en) * 2004-07-27 2006-02-01 Aventis Pharma S.A. Heterocycle -substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
EP1741709A1 (en) * 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
US7834023B2 (en) * 2006-09-20 2010-11-16 Portola Pharmaceuticals, Inc. Substituted dihydroquinazolines as platelet ADP receptor inhibitors
DK2420497T3 (en) * 2006-09-26 2016-03-07 Celgene Corp 5-substituted quinazolinone derivatives as anticancer agents
US8377949B2 (en) * 2007-08-16 2013-02-19 Boehringer Ingelheim International Gmbh Quinazolinedione chymase inhibitors
CN103288761B (zh) * 2012-02-25 2017-08-11 浙江华海药业股份有限公司 一种合成1，2，3，4‑喹唑啉‑2，4‑二酮衍生物的新方法
CN102993105B (zh) * 2012-12-19 2014-06-11 西南大学 1-甲基-2,4-喹唑啉二酮衍生物及其制备方法和应用
TW201623257A (zh) * 2014-05-09 2016-07-01 奧利安公司 藥理活性之喹唑啉二酮衍生物
US10336708B2 (en) * 2014-08-29 2019-07-02 Tokyo Ohka Kogyo Co., Ltd. Imidazole compound, metal surface treatment liquid, metal surface treatment method, and laminate production method
WO2023158845A1 (en) * 2022-02-18 2023-08-24 Musc Foundation For Researchdevelopment Small molecules targeting the vdac nadh-binding pocket to modulate cancer metabolism

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0293500A1 (en) * 1987-06-01 1988-12-07 American Cyanamid Company 3-heteroalkyl-2,4.quinzaoline-diones
CA2288140C (en) * 1997-04-25 2007-04-03 Janssen Pharmaceutica N.V. Farnesyltransferase inhibiting quinazolinones

Also Published As

Publication number Publication date
FR2837201A1 (fr) 2003-09-19
MXPA03002088A (es) 2004-12-07
PL359208A1 (en) 2003-09-22
NZ524771A (en) 2003-08-29
KR20030076350A (ko) 2003-09-26
EP1346992A1 (fr) 2003-09-24
CN1445226A (zh) 2003-10-01
EA200300272A1 (ru) 2003-10-30
AU2003201326A1 (en) 2003-10-02
BR0300698A (pt) 2004-09-08
US20030199530A1 (en) 2003-10-23
CA2423259A1 (fr) 2003-09-18
NO20031219D0 (no) 2003-03-17
NO20031219L (no) 2003-09-19
AR038988A1 (es) 2005-02-02
JP2003292491A (ja) 2003-10-15

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