ZA200301004B - Pharmaceutical compositions of estrogenic agents. - Google Patents
Pharmaceutical compositions of estrogenic agents. Download PDFInfo
- Publication number
- ZA200301004B ZA200301004B ZA200301004A ZA200301004A ZA200301004B ZA 200301004 B ZA200301004 B ZA 200301004B ZA 200301004 A ZA200301004 A ZA 200301004A ZA 200301004 A ZA200301004 A ZA 200301004A ZA 200301004 B ZA200301004 B ZA 200301004B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- pharmaceutical composition
- group
- pharmaceutically acceptable
- halogen
- Prior art date
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- 239000008194 pharmaceutical composition Substances 0.000 title claims description 51
- 239000000262 estrogen Substances 0.000 title claims description 9
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- 125000004093 cyano group Chemical class *C#N 0.000 claims description 43
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- 125000004953 trihalomethyl group Chemical group 0.000 claims description 29
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- 239000000546 pharmaceutical excipient Substances 0.000 claims description 28
- 150000001875 compounds Chemical class 0.000 claims description 27
- 125000001424 substituent group Chemical group 0.000 claims description 27
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- 125000005843 halogen group Chemical group 0.000 claims description 19
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21619200P | 2000-07-06 | 2000-07-06 |
Publications (1)
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| ZA200301004B true ZA200301004B (en) | 2004-05-05 |
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| ZA200301004A ZA200301004B (en) | 2000-07-06 | 2003-02-05 | Pharmaceutical compositions of estrogenic agents. |
Country Status (26)
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| US (2) | US20020031548A1 (ja) |
| EP (1) | EP1309327B1 (ja) |
| JP (1) | JP2004502733A (ja) |
| KR (2) | KR100894027B1 (ja) |
| CN (2) | CN101416949A (ja) |
| AR (1) | AR029538A1 (ja) |
| AT (1) | ATE453391T1 (ja) |
| AU (2) | AU7174101A (ja) |
| BR (1) | BR0112242A (ja) |
| CA (1) | CA2415058A1 (ja) |
| CY (1) | CY1109915T1 (ja) |
| DE (1) | DE60140945D1 (ja) |
| DK (1) | DK1309327T3 (ja) |
| EA (1) | EA006386B1 (ja) |
| ES (1) | ES2336304T3 (ja) |
| HU (1) | HUP0301422A3 (ja) |
| IL (2) | IL153647A0 (ja) |
| MX (1) | MXPA02012891A (ja) |
| NO (1) | NO20030030L (ja) |
| NZ (1) | NZ523330A (ja) |
| PL (1) | PL204866B1 (ja) |
| PT (1) | PT1309327E (ja) |
| SI (1) | SI1309327T1 (ja) |
| TW (1) | TWI294777B (ja) |
| WO (1) | WO2002003987A2 (ja) |
| ZA (1) | ZA200301004B (ja) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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- 2001-06-29 US US09/896,226 patent/US20020031548A1/en not_active Abandoned
- 2001-06-29 HU HU0301422A patent/HUP0301422A3/hu unknown
- 2001-06-29 BR BR0112242-8A patent/BR0112242A/pt not_active Application Discontinuation
- 2001-06-29 WO PCT/US2001/020993 patent/WO2002003987A2/en active IP Right Grant
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- 2001-06-29 KR KR1020077025013A patent/KR100894027B1/ko not_active IP Right Cessation
- 2001-06-29 JP JP2002508441A patent/JP2004502733A/ja active Pending
- 2001-06-29 AT AT01950781T patent/ATE453391T1/de not_active IP Right Cessation
- 2001-06-29 SI SI200130959T patent/SI1309327T1/sl unknown
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- 2001-06-29 CN CNA2008101697811A patent/CN101416949A/zh active Pending
- 2001-06-29 KR KR1020037000072A patent/KR100862174B1/ko not_active IP Right Cessation
- 2001-06-29 ES ES01950781T patent/ES2336304T3/es not_active Expired - Lifetime
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