ZA200209066B - Sphingosine kinase and uses thereof. - Google Patents

Sphingosine kinase and uses thereof.

Info

Publication number
ZA200209066B
ZA200209066B ZA200209066A ZA200209066A ZA200209066B ZA 200209066 B ZA200209066 B ZA 200209066B ZA 200209066 A ZA200209066 A ZA 200209066A ZA 200209066 A ZA200209066 A ZA 200209066A ZA 200209066 B ZA200209066 B ZA 200209066B
Authority
ZA
South Africa
Prior art keywords
cancers
growth
sphingosine kinase
present
cells
Prior art date
Application number
ZA200209066A
Other languages
English (en)
Inventor
Mathew Vadas
Pu Xia
Jennifer Gamble
Lijun Wang
Original Assignee
Medvet Science Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medvet Science Pty Ltd filed Critical Medvet Science Pty Ltd
Publication of ZA200209066B publication Critical patent/ZA200209066B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200209066A 2000-05-11 2002-11-07 Sphingosine kinase and uses thereof. ZA200209066B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPQ7447A AUPQ744700A0 (en) 2000-05-11 2000-05-11 A method of treatment and agents useful for same

Publications (1)

Publication Number Publication Date
ZA200209066B true ZA200209066B (en) 2004-04-07

Family

ID=3821526

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200209066A ZA200209066B (en) 2000-05-11 2002-11-07 Sphingosine kinase and uses thereof.

Country Status (17)

Country Link
US (1) US20040014635A1 (zh)
EP (1) EP1290182B1 (zh)
JP (1) JP2003532423A (zh)
CN (1) CN1436241A (zh)
AT (1) ATE492276T1 (zh)
AU (3) AUPQ744700A0 (zh)
BR (1) BR0110759A (zh)
CA (1) CA2408196A1 (zh)
DE (1) DE60143697D1 (zh)
HK (1) HK1054409A1 (zh)
IL (1) IL152672A0 (zh)
MX (1) MXPA02011112A (zh)
NO (1) NO20025375L (zh)
NZ (1) NZ543272A (zh)
RU (1) RU2326690C2 (zh)
WO (1) WO2001085953A1 (zh)
ZA (1) ZA200209066B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423527B1 (en) 1997-09-29 2002-07-23 Children's Hospital Medical Center Of Northern California Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor
CA2432978C (en) 2000-12-22 2012-08-28 Medlyte, Inc. Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor
EP1517989B1 (en) * 2002-01-17 2009-07-15 Children's Hospital & Research Center at Oakland Method for the diagnosing of sphingolipid metabolism
US7674580B2 (en) 2002-01-17 2010-03-09 Children's Hospital & Research Center At Oakland Compositions and methods for the modulation of sphingolipid metabolism and/or signaling
EP1499343A4 (en) * 2002-03-28 2005-12-28 Medvet Science Pty Ltd METHOD FOR MODULATING CELL ACTIVITY
WO2004035786A1 (en) * 2002-10-14 2004-04-29 Medvet Science Pty. Ltd. A method of modulating epithelial cell activity by modulating the functional levels of sphingosine kinase
US20040171037A1 (en) * 2002-11-19 2004-09-02 Jing Li Amplified genes involved in cancer
JP2008502604A (ja) * 2004-06-15 2008-01-31 メドベット サイエンス ピーティーワイ． リミティッド スフィンゴシンキナーゼを含む細胞活性を調整する方法、および調整するための物質、ならびにスフィンゴシンキナーゼ変種
AU2005325227B2 (en) * 2004-10-28 2012-11-01 Lpath Therapeutics, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US8324237B2 (en) * 2005-05-20 2012-12-04 Smith Charles D Methods for the treatment and prevention of inflammatory diseases
US20060270631A1 (en) * 2005-05-26 2006-11-30 Smith Charles D Methods for the treatment and prevention of angiogenic diseases
WO2006135967A1 (en) * 2005-06-21 2006-12-28 Medvet Science Pty. Ltd. Modulation of egfr signalling by modulation of sphingosine kinase signalling
WO2006135968A1 (en) * 2005-06-21 2006-12-28 Medvet Science Pty. Ltd. Modulation of sphingosine kinase signalling
US9274129B2 (en) 2006-05-31 2016-03-01 Lpath, Inc. Methods and reagents for detecting bioactive lipids
US9274130B2 (en) 2006-05-31 2016-03-01 Lpath, Inc. Prevention and treatment of pain using antibodies to lysophosphatidic acid
PT2087002E (pt) 2006-10-27 2014-11-26 Lpath Inc Composições e métodos para a ligação de esfingosina-1- fosfato
US8871202B2 (en) 2008-10-24 2014-10-28 Lpath, Inc. Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
WO2019182191A1 (ko) * 2018-03-21 2019-09-26 경북대학교 산학협력단 C0x2 아세틸화제를 유효성분으로 포함하는 퇴행성 신경질환의 예방 또는 치료용 약학적 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583160A (en) * 1989-02-03 1996-12-10 The Biomembrane Institute Methylsphingosine used to treat apoptosis
US5068175A (en) * 1989-05-26 1991-11-26 Board Of Regents, The University Of Texas Sysem Method of detecting ras oncogene related malignancies
JPH10182627A (ja) * 1996-12-20 1998-07-07 Sankyo Co Ltd 新規化合物Ｓ−１５１８３ａ及びＳ−１５１８３ｂ
AUPO900297A0 (en) * 1997-09-08 1997-10-02 Medvet Science Pty. Ltd. A method of modulating cellular activity
US6649362B2 (en) * 1997-09-08 2003-11-18 Medvet Science Pty. Ltd. Screening method for an agent having an effect on a sphingosine kinase signaling pathway
CA2329124A1 (en) * 1998-05-26 1999-12-02 Office Of The Dean Of Research And Graduate Education Sphingosine kinase, cloning, expression and methods of use
DK1091745T3 (da) * 1998-06-29 2008-12-15 Los Angeles Childrens Hospital Behandling af hyperproliferative forstyrrelser
NZ515132A (en) * 1999-05-13 2005-01-28 Johnson & Johnson Pharm Res Sphingosine kinase enzyme
JP2003512072A (ja) * 1999-10-28 2003-04-02 ワーナー−ランバート・カンパニー ヒトスフィンゴシンキナーゼ遺伝子
US6830916B2 (en) * 2000-03-02 2004-12-14 Sarah Spiegel Sphingosine kinase, cloning, expression and methods of use
DK1268509T3 (da) * 2000-04-03 2010-03-08 Daiichi Sankyo Co Ltd Type 2 isoformer af sphingosin-kinase fra pattedyr, kloning, ekspression og fremgangsmåder til anvendelse deraf
WO2004035786A1 (en) * 2002-10-14 2004-04-29 Medvet Science Pty. Ltd. A method of modulating epithelial cell activity by modulating the functional levels of sphingosine kinase

Also Published As

Publication number Publication date
NZ543272A (en) 2009-04-30
AU5600101A (en) 2001-11-20
EP1290182A1 (en) 2003-03-12
BR0110759A (pt) 2003-05-06
EP1290182B1 (en) 2010-12-22
AU2001256001B2 (en) 2007-03-15
CN1436241A (zh) 2003-08-13
NO20025375D0 (no) 2002-11-08
IL152672A0 (en) 2003-06-24
NO20025375L (no) 2003-01-07
ATE492276T1 (de) 2011-01-15
EP1290182A4 (en) 2006-01-11
RU2326690C2 (ru) 2008-06-20
MXPA02011112A (es) 2004-08-19
HK1054409A1 (zh) 2003-11-28
DE60143697D1 (de) 2011-02-03
WO2001085953A1 (en) 2001-11-15
US20040014635A1 (en) 2004-01-22
JP2003532423A (ja) 2003-11-05
AUPQ744700A0 (en) 2000-06-01
CA2408196A1 (en) 2001-11-15

Similar Documents

Publication Publication Date Title
ZA200209066B (en) Sphingosine kinase and uses thereof.
MXPA02010452A (es) Analogos de tetrahidroisoquinolina utiles como secretagogos de la hormona del crecimiento.
MXPA05007151A (es) Polimeros terminados en maleimida hidroliticamente estables.
HU9503702D0 (en) Use of modafinil for the treatment of sleep apnoea and ventilation problems of central origin
DE69405583T2 (de) Minimalinvasive monopole phasengesteuerte strahler für hyperthermie zur behandlung von brustkarzinomen
BG105292A (en) Novel hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof
EP1553225A4 (en) VELOURSKUNSTLEDER AND ITS MANUFACTURE
AU6769801A (en) Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them
MY138125A (en) Flavour concentrates
AP2003002785A0 (en) Treatment of t cell disorders
NZ512659A (en) Use of growth hormone secretagogues for treatment of physical performance decline
EP1532131A4 (en) COMPOUNDS OF THE MOTILID TYPE
MXPA02007903A (es) Uso de acido 2-metil-tiazolidina-2, 4-dicarboxilico (2-mtdc) y/o sales fisiologicamente compatibles para tratar y/o prevenir canceres.
EP1328264A4 (en) USE OF ESTRAMUSTIN PHOSPHATE IN THE TREATMENT OF BONE MEASURES
IL151335A0 (en) 103p2d6: tissue specific protein highly expressed in various cancers
MXPA04004526A (es) N-metil-homocisteinas, su uso y metodo para su produccion.
AU2002220712A1 (en) Stem cells, method for expansion in vitro and use thereof
GB9425071D0 (en) Chondrocyte cell lines
ATE454168T1 (de) Calcium-ergänzung zur senkung des risikos für prostatakrebs
EP1385497A4 (en) METHOD FOR PREVENTING OR TREATING BREAST CANCER, PROSTATE AND / OR COLUMN OF UTERUS USING N, N-DIMETHYLGLYCIN
UA49431A (uk) Регулятор росту рослин
UA32153A (uk) Спосіб формування трансплантату для зведення на промежину при черевно-анальних резекціях прямої кишки
UA32302A (uk) Спосіб усунення післяопераційних деформацій м'яких тканин
CA98218S (en) Knee prosthesis
UA49216A (uk) Засіб для лікування ускладнень після видалення злоякісних новоутворень шкіри