ZA200206795B - Pluraflavins and derivatives thereof, process for their preparation and use thereof. - Google Patents

Pluraflavins and derivatives thereof, process for their preparation and use thereof. Download PDF

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Publication number
ZA200206795B
ZA200206795B ZA200206795A ZA200206795A ZA200206795B ZA 200206795 B ZA200206795 B ZA 200206795B ZA 200206795 A ZA200206795 A ZA 200206795A ZA 200206795 A ZA200206795 A ZA 200206795A ZA 200206795 B ZA200206795 B ZA 200206795B
Authority
ZA
South Africa
Prior art keywords
compound
formula
groups
physiologically acceptable
derivative
Prior art date
Application number
ZA200206795A
Other languages
English (en)
Inventor
Laszio Vertesy
Klaus Ehrlich
Martin Knauf
Joachim Wink
Francis P Barbone
Elaine A Powers
Elizabeth A Cashman
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ZA200206795B publication Critical patent/ZA200206795B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/58Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound through only acyclic carbon atoms to a non-saccharide heterocyclic ring, e.g. bleomycin, phleomycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA200206795A 2000-02-18 2002-08-26 Pluraflavins and derivatives thereof, process for their preparation and use thereof. ZA200206795B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00103540A EP1125944A1 (de) 2000-02-18 2000-02-18 Pluraflavine und Derivate davon, Verfahren zu ihrer Herstellung und Verwendung derselben

Publications (1)

Publication Number Publication Date
ZA200206795B true ZA200206795B (en) 2003-11-19

Family

ID=8167898

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200206795A ZA200206795B (en) 2000-02-18 2002-08-26 Pluraflavins and derivatives thereof, process for their preparation and use thereof.

Country Status (31)

Country Link
US (1) US6500936B2 (cs)
EP (2) EP1125944A1 (cs)
JP (1) JP4801307B2 (cs)
KR (1) KR100743380B1 (cs)
CN (1) CN1162441C (cs)
AR (1) AR027436A1 (cs)
AT (1) ATE255120T1 (cs)
AU (2) AU4240401A (cs)
BR (1) BR0108128A (cs)
CA (1) CA2400237C (cs)
CZ (1) CZ303810B6 (cs)
DE (1) DE60101313T2 (cs)
DK (1) DK1259523T3 (cs)
EE (1) EE05137B1 (cs)
ES (1) ES2207609T3 (cs)
HK (1) HK1052709B (cs)
HR (1) HRP20020672B1 (cs)
HU (1) HU228332B1 (cs)
IL (2) IL151216A0 (cs)
ME (1) ME00179B (cs)
MX (1) MXPA02006919A (cs)
NO (1) NO323413B1 (cs)
PL (1) PL204842B1 (cs)
PT (1) PT1259523E (cs)
RS (1) RS49991B (cs)
RU (1) RU2255940C2 (cs)
SI (1) SI1259523T1 (cs)
SK (1) SK286691B6 (cs)
TR (1) TR200302180T4 (cs)
WO (1) WO2001060832A2 (cs)
ZA (1) ZA200206795B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989386B2 (en) * 2002-04-30 2006-01-24 Dana-Farber Cancer Institute Pharmaceutically active ornithine derivatives, ammonium salts thereof and methods of making same
CN101921300B (zh) * 2009-06-10 2014-04-02 上海来益生物药物研究开发中心有限责任公司 一种异黄酮苷类化合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3782930T2 (de) * 1986-07-21 1993-04-29 Kyowa Hakko Kogyo Kk Neue mittel dc-92b und dc-92d, sowie deren verfahren zur herstellung.
WO1990000935A1 (en) * 1988-07-22 1990-02-08 Masco Corporation Of Indiana A small hand-held shower head for domestic sinks connected to a faucet
US5001058A (en) * 1988-09-19 1991-03-19 Bristol-Myers Company BU-3839T antibiotic
PT93070A (pt) * 1989-02-07 1990-08-31 Abbott Lab Processo de preparacao de altromicinas e de composicoes farmaceuticas que as contem
US5168100A (en) * 1990-03-16 1992-12-01 Sapporo Breweries Limited Hp530 compounds and process for preparing the same
WO2009009435A2 (en) * 2007-07-06 2009-01-15 Rite-Hite Holding Corporation Retractable safety barriers and methods of operating same

Also Published As

Publication number Publication date
EE05137B1 (et) 2009-02-16
AU4240401A (en) 2001-08-27
BR0108128A (pt) 2003-02-25
NO20023845L (no) 2002-10-10
HRP20020672A2 (en) 2004-12-31
DE60101313T2 (de) 2004-09-30
CA2400237C (en) 2008-12-30
IL151216A (en) 2009-12-24
HK1052709A1 (en) 2003-11-21
PL204842B1 (pl) 2010-02-26
MEP28608A (en) 2010-10-10
RS49991B (sr) 2008-09-29
US6500936B2 (en) 2002-12-31
HRP20020672B1 (en) 2010-12-31
HUP0204393A3 (en) 2007-10-29
JP4801307B2 (ja) 2011-10-26
YU57602A (sh) 2005-11-28
DK1259523T3 (da) 2004-03-22
CN1404484A (zh) 2003-03-19
ATE255120T1 (de) 2003-12-15
ME00179B (me) 2011-02-10
RU2255940C2 (ru) 2005-07-10
SK11802002A3 (sk) 2003-02-04
SI1259523T1 (en) 2004-04-30
PT1259523E (pt) 2004-04-30
WO2001060832A2 (en) 2001-08-23
KR100743380B1 (ko) 2007-07-30
EP1259523A2 (en) 2002-11-27
SK286691B6 (sk) 2009-03-05
DE60101313D1 (de) 2004-01-08
EP1125944A1 (de) 2001-08-22
NO323413B1 (no) 2007-04-30
CN1162441C (zh) 2004-08-18
IL151216A0 (en) 2003-04-10
MXPA02006919A (es) 2004-04-05
CZ20022826A3 (cs) 2002-11-13
AR027436A1 (es) 2003-03-26
PL358297A1 (en) 2004-08-09
KR20020086539A (ko) 2002-11-18
TR200302180T4 (tr) 2004-03-22
HUP0204393A2 (hu) 2003-07-28
ES2207609T3 (es) 2004-06-01
WO2001060832A3 (en) 2002-01-31
JP2003523346A (ja) 2003-08-05
HK1052709B (zh) 2005-02-04
NO20023845D0 (no) 2002-08-14
CZ303810B6 (cs) 2013-05-15
RU2002124772A (ru) 2004-02-20
EP1259523B1 (en) 2003-11-26
HU228332B1 (en) 2013-03-28
US20020028921A1 (en) 2002-03-07
CA2400237A1 (en) 2001-08-23
EE200200438A (et) 2003-12-15
AU2001242404B2 (en) 2005-04-14

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