ZA200205596B - Octahydro-2H-Pyrido[1,2-A]pyrazine compounds, a process for their preparation and pharmaceutical compositions containing them. - Google Patents

Octahydro-2H-Pyrido[1,2-A]pyrazine compounds, a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
ZA200205596B
ZA200205596B ZA200205596A ZA200205596A ZA200205596B ZA 200205596 B ZA200205596 B ZA 200205596B ZA 200205596 A ZA200205596 A ZA 200205596A ZA 200205596 A ZA200205596 A ZA 200205596A ZA 200205596 B ZA200205596 B ZA 200205596B
Authority
ZA
South Africa
Prior art keywords
octahydro
pyrido
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA200205596A
Other languages
English (en)
Inventor
Solo Goldstein
Guillaume Poissonnet
Jean-Gilles Parmentier
Pierre Lestage
Brian Lockhart
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of ZA200205596B publication Critical patent/ZA200205596B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
ZA200205596A 2001-07-12 2002-07-12 Octahydro-2H-Pyrido[1,2-A]pyrazine compounds, a process for their preparation and pharmaceutical compositions containing them. ZA200205596B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0109260A FR2827288B1 (fr) 2001-07-12 2001-07-12 Nouveaux derives d'octahydro-2h-pyrido[1,2-a]pyrazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA200205596B true ZA200205596B (en) 2003-03-27

Family

ID=8865405

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200205596A ZA200205596B (en) 2001-07-12 2002-07-12 Octahydro-2H-Pyrido[1,2-A]pyrazine compounds, a process for their preparation and pharmaceutical compositions containing them.

Country Status (25)

Country Link
US (1) US6992085B2 (ru)
EP (1) EP1275647B1 (ru)
JP (1) JP3950018B2 (ru)
KR (1) KR100485020B1 (ru)
CN (1) CN1197863C (ru)
AR (1) AR036166A1 (ru)
AT (1) ATE254124T1 (ru)
AU (1) AU2002300094B2 (ru)
BR (1) BR0202681A (ru)
CA (1) CA2394027C (ru)
DE (1) DE60200089T2 (ru)
DK (1) DK1275647T3 (ru)
EA (1) EA005160B1 (ru)
ES (1) ES2210219T3 (ru)
FR (1) FR2827288B1 (ru)
HK (1) HK1050682A1 (ru)
HU (1) HUP0202282A3 (ru)
MX (1) MXPA02006699A (ru)
NO (1) NO322966B1 (ru)
NZ (1) NZ520120A (ru)
PL (1) PL355034A1 (ru)
PT (1) PT1275647E (ru)
SI (1) SI1275647T1 (ru)
TR (1) TR200302001T4 (ru)
ZA (1) ZA200205596B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004089410A1 (ja) * 2003-04-03 2004-10-21 Kyowa Hakko Kogyo Co., Ltd. 神経因性疼痛の予防及び／または治療剤
MY141255A (en) * 2003-12-11 2010-03-31 Memory Pharm Corp Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
FR2866647B1 (fr) * 2004-02-20 2006-10-27 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2006000914A1 (en) * 2004-06-22 2006-01-05 Pfizer Products Inc. Diazabicyclic histamine-3 receptor antagonists
RU2442775C2 (ru) * 2005-07-04 2012-02-20 Хай Пойнт Фармасьютикалс, ЛЛС Антагонисты гистаминовых н3-рецепторов
EP2386554A1 (en) * 2005-07-04 2011-11-16 High Point Pharmaceuticals, LLC Compounds active at the histamine H3 receptor
JP2009531314A (ja) * 2006-03-10 2009-09-03 ニューロジェン・コーポレーション ピペラジニルオキソアルキルテトラヒドロイソキノリン類および関連類似物
KR100871691B1 (ko) 2006-10-16 2008-12-05 삼성전자주식회사 병렬 비트 테스트 방법 및 그 방법을 사용하는 반도체메모리 장치
WO2018021447A1 (ja) 2016-07-28 2018-02-01 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する含窒素縮環化合物
WO2019146739A1 (ja) 2018-01-26 2019-08-01 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する縮環化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3388128A (en) * 1965-09-03 1968-06-11 Allan R. Day Substituted 1, 4-diazabicyclo [4. 4. 9] decanes
GB8518236D0 (en) * 1985-07-19 1985-08-29 Beecham Group Plc Compounds
WO1994006794A1 (en) * 1992-09-24 1994-03-31 National Institutes Of Health Aralkyl diazabicycloalkane derivatives for cns disorders
US6231833B1 (en) * 1999-08-05 2001-05-15 Pfizer Inc 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
US5731307A (en) * 1994-09-30 1998-03-24 Pfizer, Inc. Neuroleptic 2,7-disubtituted perhydro-1h-pyrido 1, 2-A!pyrazines
ES2274795T3 (es) * 1999-07-19 2007-06-01 Merck Frosst Canada Ltd. Pirazinonas, composiciones que contienen tales compuestos.

Also Published As

Publication number Publication date
DE60200089D1 (de) 2003-12-18
US6992085B2 (en) 2006-01-31
EP1275647B1 (fr) 2003-11-12
KR20030007159A (ko) 2003-01-23
KR100485020B1 (ko) 2005-04-25
US20030195216A1 (en) 2003-10-16
PT1275647E (pt) 2004-03-31
ATE254124T1 (de) 2003-11-15
DK1275647T3 (da) 2004-03-15
DE60200089T2 (de) 2004-09-09
TR200302001T4 (tr) 2004-01-21
EP1275647A1 (fr) 2003-01-15
HU0202282D0 (ru) 2002-09-28
PL355034A1 (en) 2003-01-13
EA200200663A1 (ru) 2003-02-27
MXPA02006699A (es) 2005-08-16
CA2394027C (fr) 2008-01-08
ES2210219T3 (es) 2004-07-01
HUP0202282A3 (en) 2003-11-28
CN1397557A (zh) 2003-02-19
CA2394027A1 (fr) 2003-01-12
NZ520120A (en) 2004-03-26
HK1050682A1 (en) 2003-07-04
AU2002300094B2 (en) 2007-06-14
SI1275647T1 (en) 2004-02-29
FR2827288B1 (fr) 2003-10-31
BR0202681A (pt) 2003-05-06
NO20023345L (no) 2003-01-13
JP2003064081A (ja) 2003-03-05
CN1197863C (zh) 2005-04-20
NO322966B1 (no) 2006-12-18
AR036166A1 (es) 2004-08-18
EA005160B1 (ru) 2004-12-30
JP3950018B2 (ja) 2007-07-25
NO20023345D0 (no) 2002-07-11
HUP0202282A2 (hu) 2003-03-28
FR2827288A1 (fr) 2003-01-17

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