ZA200202726B - Neutral-cationic lipid for nucleic acid and drug delivery. - Google Patents
Neutral-cationic lipid for nucleic acid and drug delivery. Download PDFInfo
- Publication number
- ZA200202726B ZA200202726B ZA200202726A ZA200202726A ZA200202726B ZA 200202726 B ZA200202726 B ZA 200202726B ZA 200202726 A ZA200202726 A ZA 200202726A ZA 200202726 A ZA200202726 A ZA 200202726A ZA 200202726 B ZA200202726 B ZA 200202726B
- Authority
- ZA
- South Africa
- Prior art keywords
- lipid
- liposomes
- composition
- january
- nucleic acid
- Prior art date
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Landscapes
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US (2) | US6974589B1 (fr) |
EP (1) | EP1223916B1 (fr) |
JP (1) | JP2003511405A (fr) |
KR (1) | KR100723852B1 (fr) |
CN (2) | CN1915968A (fr) |
AT (1) | ATE276744T1 (fr) |
AU (2) | AU7868400A (fr) |
CA (1) | CA2386164A1 (fr) |
DE (1) | DE60014133T2 (fr) |
DK (1) | DK1223916T3 (fr) |
ES (1) | ES2226932T3 (fr) |
HU (1) | HUP0203117A3 (fr) |
IL (1) | IL148968A0 (fr) |
MX (1) | MXPA02002899A (fr) |
NO (1) | NO20021615D0 (fr) |
WO (2) | WO2001026625A2 (fr) |
ZA (1) | ZA200202726B (fr) |
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US7238368B2 (en) | 1999-04-23 | 2007-07-03 | Alza Corporation | Releasable linkage and compositions containing same |
AU769425B2 (en) | 1999-04-23 | 2004-01-29 | Alza Corporation | Conjugate having a cleavable linkage for use in a liposome |
US7303760B2 (en) | 1999-04-23 | 2007-12-04 | Alza Corporation | Method for treating multi-drug resistant tumors |
US20040197390A1 (en) * | 2001-05-29 | 2004-10-07 | Shi-Kun Huang | Neutral-cationic lipid for systemic delivery of factor VIII gene |
WO2001026625A2 (fr) | 1999-10-08 | 2001-04-19 | Alza Corp | Lipide neutre-cationique destine au transfert d'acides nucleiques et de medicaments |
DE10207177A1 (de) * | 2002-02-19 | 2003-09-04 | Novosom Ag | Fakultativ kationische Lipide |
CN102940891B (zh) * | 2004-05-05 | 2016-02-24 | 赛伦斯治疗有限公司 | 脂质、脂质复合物及其应用 |
EP1935434A1 (fr) * | 2006-12-19 | 2008-06-25 | Novosom AG | Construction et utilisation d'éléments améliorant la transfection |
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CN101475503B (zh) * | 2008-12-15 | 2012-02-15 | 山东大学 | 一种新型阳离子类脂及其制备方法和应用 |
EP2532649B1 (fr) * | 2011-06-07 | 2015-04-08 | Incella GmbH | Lipides aminés, leur synthèse et utilisations associées |
IL280771B2 (en) | 2011-06-08 | 2024-03-01 | Shire Human Genetic Therapies | Preparations of lipid nanoparticles and methods for administration of mRNA |
WO2013151326A1 (fr) * | 2012-04-04 | 2013-10-10 | Samyang Biopharmaceuticals Corporation | Procédé de préparation d'une composition pour administrer un médicament anionique |
CN105585598B (zh) * | 2014-10-20 | 2019-02-19 | 湖南师范大学 | 甘露糖衍生物阳离子脂质体纳米颗粒的制备方法 |
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CN107200841B (zh) * | 2016-03-17 | 2019-02-01 | 华东师范大学 | 一种培化二酰甘油的合成方法 |
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US5855911A (en) | 1995-08-29 | 1999-01-05 | Board Of Regents, The University Of Texas System | Liposomal phosphodiester, phosphorothioate, and P-ethoxy oligonucleotides |
TW520297B (en) * | 1996-10-11 | 2003-02-11 | Sequus Pharm Inc | Fusogenic liposome composition and method |
US6056973A (en) * | 1996-10-11 | 2000-05-02 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method of preparation |
WO2000030444A1 (fr) | 1998-11-25 | 2000-06-02 | Vanderbilt University | Liposomes cationiques pour transfert genique |
WO2001026625A2 (fr) | 1999-10-08 | 2001-04-19 | Alza Corp | Lipide neutre-cationique destine au transfert d'acides nucleiques et de medicaments |
-
2000
- 2000-10-06 WO PCT/US2000/027683 patent/WO2001026625A2/fr not_active Application Discontinuation
- 2000-10-06 AU AU78684/00A patent/AU7868400A/en not_active Withdrawn
- 2000-10-10 CA CA002386164A patent/CA2386164A1/fr not_active Abandoned
- 2000-10-10 ES ES00970729T patent/ES2226932T3/es not_active Expired - Lifetime
- 2000-10-10 JP JP2001529419A patent/JP2003511405A/ja not_active Abandoned
- 2000-10-10 CN CNA2006101062621A patent/CN1915968A/zh active Pending
- 2000-10-10 KR KR1020027004490A patent/KR100723852B1/ko not_active IP Right Cessation
- 2000-10-10 MX MXPA02002899A patent/MXPA02002899A/es not_active Application Discontinuation
- 2000-10-10 CN CN00813919A patent/CN1378536A/zh active Pending
- 2000-10-10 AT AT00970729T patent/ATE276744T1/de not_active IP Right Cessation
- 2000-10-10 IL IL14896800A patent/IL148968A0/xx unknown
- 2000-10-10 EP EP00970729A patent/EP1223916B1/fr not_active Expired - Lifetime
- 2000-10-10 DE DE60014133T patent/DE60014133T2/de not_active Expired - Fee Related
- 2000-10-10 DK DK00970729T patent/DK1223916T3/da active
- 2000-10-10 US US09/685,940 patent/US6974589B1/en not_active Expired - Lifetime
- 2000-10-10 AU AU80064/00A patent/AU778817B2/en not_active Ceased
- 2000-10-10 WO PCT/US2000/027974 patent/WO2001026629A2/fr active IP Right Grant
- 2000-10-10 HU HU0203117A patent/HUP0203117A3/hu unknown
-
2002
- 2002-04-05 NO NO20021615A patent/NO20021615D0/no not_active Application Discontinuation
- 2002-04-08 ZA ZA200202726A patent/ZA200202726B/en unknown
-
2005
- 2005-05-19 US US11/133,879 patent/US20050260261A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1223916A2 (fr) | 2002-07-24 |
IL148968A0 (en) | 2002-11-10 |
AU7868400A (en) | 2001-04-23 |
DE60014133T2 (de) | 2005-02-03 |
CN1378536A (zh) | 2002-11-06 |
WO2001026629A3 (fr) | 2002-05-10 |
JP2003511405A (ja) | 2003-03-25 |
WO2001026625A2 (fr) | 2001-04-19 |
EP1223916B1 (fr) | 2004-09-22 |
KR20020063875A (ko) | 2002-08-05 |
AU778817B2 (en) | 2004-12-23 |
NO20021615L (no) | 2002-04-05 |
MXPA02002899A (es) | 2002-10-23 |
AU8006400A (en) | 2001-04-23 |
US20050260261A1 (en) | 2005-11-24 |
DE60014133D1 (de) | 2004-10-28 |
HUP0203117A2 (hu) | 2003-01-28 |
US6974589B1 (en) | 2005-12-13 |
ATE276744T1 (de) | 2004-10-15 |
ES2226932T3 (es) | 2005-04-01 |
HUP0203117A3 (en) | 2005-06-28 |
DK1223916T3 (da) | 2005-01-31 |
CN1915968A (zh) | 2007-02-21 |
NO20021615D0 (no) | 2002-04-05 |
KR100723852B1 (ko) | 2007-05-31 |
WO2001026629A2 (fr) | 2001-04-19 |
CA2386164A1 (fr) | 2001-04-19 |
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