ZA200202426B - Pyrimidine derivatives, process for preparing the derivatives and drugs containing the same as the active ingredient. - Google Patents

Pyrimidine derivatives, process for preparing the derivatives and drugs containing the same as the active ingredient.

Info

Publication number
ZA200202426B
ZA200202426B ZA200202426A ZA200202426A ZA200202426B ZA 200202426 B ZA200202426 B ZA 200202426B ZA 200202426 A ZA200202426 A ZA 200202426A ZA 200202426 A ZA200202426 A ZA 200202426A ZA 200202426 B ZA200202426 B ZA 200202426B
Authority
ZA
South Africa
Prior art keywords
derivatives
preparing
active ingredient
same
drugs containing
Prior art date
Application number
ZA200202426A
Other languages
English (en)
Inventor
Tsutomu Kojima
Katsutoshi Hachiya
Shinsuke Hashimoto
Takanori Okada
Takahiro Motoi
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of ZA200202426B publication Critical patent/ZA200202426B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200202426A 1999-09-27 2002-03-26 Pyrimidine derivatives, process for preparing the derivatives and drugs containing the same as the active ingredient. ZA200202426B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27184399 1999-09-27

Publications (1)

Publication Number Publication Date
ZA200202426B true ZA200202426B (en) 2003-08-19

Family

ID=17505658

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200202426A ZA200202426B (en) 1999-09-27 2002-03-26 Pyrimidine derivatives, process for preparing the derivatives and drugs containing the same as the active ingredient.

Country Status (12)

Country Link
EP (1) EP1219608A4 (no)
KR (1) KR20020028232A (no)
CN (1) CN1399632A (no)
AU (1) AU7444600A (no)
BR (1) BR0014319A (no)
CA (1) CA2385292A1 (no)
HU (1) HUP0203835A3 (no)
MX (1) MXPA02003186A (no)
NO (1) NO20021527L (no)
NZ (1) NZ517962A (no)
WO (1) WO2001023361A1 (no)
ZA (1) ZA200202426B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001277736A1 (en) * 2000-08-10 2002-02-25 Ono Pharmaceutical Co. Ltd. 2-(5-amino-6-oxo-2-phenyl-1,6-dihydro-1-pyrimidyl)-n-(1-(2-( -t-butyl-1,3,4-oxadiazolyl)carbonyl)-2-(r,s)-methylpropyl) acetamide hydrochloride
EP1318150A4 (en) * 2000-09-08 2004-04-14 Ono Pharmaceutical Co NEW CRYSTALS OF 1,3,4-OXADIAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION OF THE CRYSTALS AND THE MEDICINAL PRODUCTS CONTAINING THEM AS AN ACTIVE SUBSTANCE
IL148924A (en) * 2002-03-26 2015-06-30 Mor Research Applic Ltd Use of substances that inhibit intracellular elastase activity in the preparation of a drug for the treatment and / or prevention of necrosis of cells and related diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216272D0 (en) * 1991-08-15 1992-09-09 Ici Plc Substituted heterocycles
WO1998024806A2 (en) * 1996-12-06 1998-06-11 Cortech, Inc. Substituted oxadiazole, thiadiazole and triazole serine protease inhibitors
ZA9810490B (en) * 1997-12-03 1999-05-20 Dainippon Pharmaceutical Co 2-Aryl-8-oxodihydropurine derivative process for the preparation thereof pharmaceutical composition containing the same and intermediate therefor

Also Published As

Publication number Publication date
KR20020028232A (ko) 2002-04-16
WO2001023361A1 (fr) 2001-04-05
CA2385292A1 (en) 2001-04-05
HUP0203835A2 (en) 2003-05-28
CN1399632A (zh) 2003-02-26
AU7444600A (en) 2001-04-30
BR0014319A (pt) 2002-07-16
NO20021527D0 (no) 2002-03-26
EP1219608A4 (en) 2003-01-08
EP1219608A1 (en) 2002-07-03
MXPA02003186A (es) 2002-10-31
NO20021527L (no) 2002-05-27
NZ517962A (en) 2003-11-28
HUP0203835A3 (en) 2003-07-28

Similar Documents

Publication Publication Date Title
HUP0204170A3 (en) 5-thia-omega-substituted phenyl-prostaglandin e derivatives, process for producing the same and drugs containing the same as the active ingredient
HK1044945A1 (en) 16-Halogen-epothilone derivatives, method for producing them and their pharmaceutical use.
AU3076700A (en) 2h-phthalazin-1-one derivatives and drugs comprising these derivatives as the active ingredient
HUP0201832A3 (en) Quinazoline derivatives, pharmaceutical compositions containing these compounds, and processes for preparing them
ZA200201511B (en) 3(5)-amino-pyrazole derivatives, process for their preparation and their use as antitumor agents.
MXPA02001497A (es) Derivados de 3-(5)-ureido-pirazol, procedimiento para su preparacion y sus uso como agentes antitumorales.
HUP0104964A3 (en) Quinazoline derivatives as angiogenesis inhibitors, process for their preparation and medicaments containing the compounds
AU7962200A (en) Novel indole derivatives and drugs containing the same as the active ingredient
HUP0203385A3 (en) Pyrimidine derivatives, process for their preparation, pharmaceutical compositions containing them and their use
AU2001241056A1 (en) Spiro compounds, process for preparing the same and use thereof as drugs
HUP0400155A3 (en) N-phenylarylsulfonamide compound, drug containing the compound as active ingredient, intermediate for the compound, and processes for producing the same
AU7961200A (en) Urea derivative, process for producing the same, and medicine containing the urea derivative
HK1015789A1 (en) Propanolamine derivatives, processes for their preparation, pharmaceuticals comprising these compounds, and their use.
ZA200109602B (en) Purine derivatives, preparation method and pharmaceutical compositions containing same.
ZA200007415B (en) Amino acid derivatives and drugs containing the same as the active ingredient.
MXPA01008148A (es) Derivados de epotilona, metodo para su produccion y su uso farmaceutico.
AU6309698A (en) Drugs containing aminopyridine derivatives as the active ingredient
ZA200001746B (en) 3-amino-3-arylpropan-1-ol derivatives, and their preparation and use.
AU2001234107A1 (en) Benzoic acid derivatives, process for producing the same and drugs containing the same as the active ingredient
AU1650501A (en) 1,3,4-oxadiazoline derivatives and drugs containing these derivatives as the active ingredient
HK1050003A1 (en) Naphthyridine derivatives, processes for their preparation, their use and pharmaceutical compositions comprising them.
HUP0201552A3 (en) Quaternary ammonium derivatives, method for preparing the same and their pharmaceutical use
ZA200203311B (en) Pharmaceutical carrier formulation.
ZA200202426B (en) Pyrimidine derivatives, process for preparing the derivatives and drugs containing the same as the active ingredient.
EP1234834A4 (en) 1,3,4-OXADIAZOLINE-2-ONE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING SUCH DERIVATIVES USEFUL AS ACTIVE INGREDIENT