ZA200201969B - Oral recombinant Lactobacilli vaccines. - Google Patents
Oral recombinant Lactobacilli vaccines. Download PDFInfo
- Publication number
- ZA200201969B ZA200201969B ZA200201969A ZA200201969A ZA200201969B ZA 200201969 B ZA200201969 B ZA 200201969B ZA 200201969 A ZA200201969 A ZA 200201969A ZA 200201969 A ZA200201969 A ZA 200201969A ZA 200201969 B ZA200201969 B ZA 200201969B
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- ZA
- South Africa
- Prior art keywords
- vaccine
- plantarum
- antigen
- lactobacillus
- bacterium
- Prior art date
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- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
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- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P31/10—Antimycotics
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- A61P31/12—Antivirals
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
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- Public Health (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99203056A EP1084709A1 (en) | 1999-09-17 | 1999-09-17 | Oral recombinant lactobacilli vaccines |
Publications (1)
Publication Number | Publication Date |
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ZA200201969B true ZA200201969B (en) | 2003-08-27 |
Family
ID=8240652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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ZA200201969A ZA200201969B (en) | 1999-09-17 | 2002-03-08 | Oral recombinant Lactobacilli vaccines. |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP1084709A1 (zh) |
JP (1) | JP2003509469A (zh) |
CN (1) | CN1387442A (zh) |
AP (1) | AP2002002445A0 (zh) |
AU (1) | AU7433700A (zh) |
CA (1) | CA2383433A1 (zh) |
IL (1) | IL148713A0 (zh) |
OA (1) | OA12023A (zh) |
WO (1) | WO2001021200A1 (zh) |
ZA (1) | ZA200201969B (zh) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7220418B1 (en) | 1999-07-05 | 2007-05-22 | Vlaams Interuniversitair Instituut Voor Biotechnologie | Delivery of trefoil peptides |
US7060687B2 (en) | 2001-02-07 | 2006-06-13 | Genmont Biotechnology Co. | Live vaccines for allergy treatment |
JP4059648B2 (ja) * | 2001-08-28 | 2008-03-12 | 独立行政法人科学技術振興機構 | 経口用サイトカイン誘導剤 |
GB0124580D0 (en) * | 2001-10-12 | 2001-12-05 | Univ Reading | New composition |
EP1319410A1 (en) * | 2001-12-11 | 2003-06-18 | Société des Produits Nestlé S.A. | Use of micro-organisms for a directed delivery of substances to specific parts of the gut |
US20040043003A1 (en) * | 2002-01-31 | 2004-03-04 | Wei Chen | Clinical grade vectors based on natural microflora for use in delivering therapeutic compositions |
CA2492685A1 (en) * | 2002-06-18 | 2003-12-24 | Universite Catholique De Louvain | Cell wall mutants for delivery of biologically active compounds |
NZ544116A (en) * | 2003-05-22 | 2008-03-28 | Synbiotics Ab | A probiotic composition comprising at least two lactic acid bacterial strains which are able to colonise the gastrointestinal tracts in combination with having intestinal survival property, intestinal binding property, an infection protection property and a fiber fermenting property |
EP1680508B1 (en) * | 2003-10-28 | 2011-03-30 | Friesland Brands B.V. | Site-specific intestinal delivery and/or production of biologically active substances |
US8821893B2 (en) * | 2004-07-02 | 2014-09-02 | Bio Peptides, Corp. | Oral vaccine for Borrelia |
EP1723965A1 (en) * | 2005-05-18 | 2006-11-22 | Stallergenes Sa | Compositions for antigen-specific induction of immuno-tolerance via oral immunization |
JPWO2006126682A1 (ja) * | 2005-05-27 | 2008-12-25 | 財団法人化学及血清療法研究所 | アルツハイマー病の予防・治療用ワクチン |
PL1951273T3 (pl) * | 2005-10-06 | 2014-07-31 | Probi Ab | Zastosowanie lactobacillus do leczenia chorób autoimmunologicznych |
WO2007106073A2 (en) | 2006-03-02 | 2007-09-20 | University Of Massachusetts | Modified pathogens for use as vaccines |
JP5791009B2 (ja) * | 2008-12-22 | 2015-10-07 | アサヒグループホールディングス株式会社 | 乳酸菌およびそれらを用いた飲食物又は化粧品 |
DK2694101T3 (en) | 2011-04-06 | 2017-01-09 | Biovaxim Ltd | Pharmaceutical compositions for the prevention and / or treatment of HIV disease in humans |
CN103732248B (zh) * | 2011-04-06 | 2018-08-28 | 拜欧瓦克西姆有限公司 | 用于预防和/或治疗人中的hiv疾病的药物组合物 |
CN102580118B (zh) * | 2012-02-24 | 2014-03-12 | 重庆大学 | 志贺样毒素Stx1B口服疫苗的制备方法及其产品 |
WO2014047625A1 (en) * | 2012-09-24 | 2014-03-27 | Montana State University | Recombinant lactococcus lactis expressing escherichia coli colonization factor antigen i (cfa/i) fimbriae and their methods of use |
US10314916B2 (en) | 2013-06-11 | 2019-06-11 | House Wellness Foods Corporation | Carrier for delivery of substance to phagocytes |
AU2019245479A1 (en) * | 2018-03-31 | 2020-10-29 | Pebble Labs Usa Inc. | Systems, methods and composition of using RNase III mutants to produce sRNA to control host pathogen infection |
AU2021380725A1 (en) * | 2020-11-10 | 2023-07-06 | Elanco Us Inc. | Immunogenic probiotic compositions and methods of use including in vaccination |
GB202019767D0 (en) | 2020-12-15 | 2021-01-27 | Chain Biotechnology Ltd | Compostitions and methods |
CN113308396B (zh) * | 2021-05-18 | 2023-03-21 | 上海市公共卫生临床中心 | 一种植物乳杆菌及在制备新冠疫苗免疫增强剂中的应用 |
CN113304254A (zh) * | 2021-06-07 | 2021-08-27 | 吉林大学 | 一种微小隐孢子虫Cp15重组侵入型乳酸菌活载体疫苗 |
CN114561313B (zh) * | 2021-08-26 | 2022-09-13 | 佛山市孛特碧欧微生物科技有限公司 | 格氏乳杆菌及其应用 |
GB202209115D0 (en) | 2022-06-21 | 2022-08-10 | Chain Biotechnology Ltd | Compositions and methods |
DE102022119024A1 (de) * | 2022-07-28 | 2024-02-08 | INM - Leibniz-Institut für Neue Materialien gemeinnützige Gesellschaft mit beschränkter Haftung | Neuartige genetische Werkzeuge |
CN117586935B (zh) * | 2023-12-01 | 2024-05-10 | 华中农业大学 | 用于产肠毒素大肠杆菌k99菌毛型的乳酸乳球菌载体口服疫苗及应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8700890A (nl) * | 1987-04-15 | 1988-11-01 | Tno | Transformatie van lactobacillus, daarbij bruikbare recombinante plasmiden, getransformeerde lactobacillus species en gebruik daarvan. |
GB9718616D0 (en) * | 1997-09-02 | 1997-11-05 | Queen Mary & Westfield College | Oral vaccine |
-
1999
- 1999-09-17 EP EP99203056A patent/EP1084709A1/en not_active Withdrawn
-
2000
- 2000-09-18 IL IL14871300A patent/IL148713A0/xx unknown
- 2000-09-18 CA CA002383433A patent/CA2383433A1/en not_active Abandoned
- 2000-09-18 CN CN00815334A patent/CN1387442A/zh active Pending
- 2000-09-18 AU AU74337/00A patent/AU7433700A/en not_active Abandoned
- 2000-09-18 AP APAP/P/2002/002445A patent/AP2002002445A0/en unknown
- 2000-09-18 EP EP00962689A patent/EP1212083A1/en not_active Withdrawn
- 2000-09-18 WO PCT/GB2000/003575 patent/WO2001021200A1/en not_active Application Discontinuation
- 2000-09-18 OA OA1200200076A patent/OA12023A/en unknown
- 2000-09-18 JP JP2001524624A patent/JP2003509469A/ja active Pending
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2002
- 2002-03-08 ZA ZA200201969A patent/ZA200201969B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP1084709A9 (en) | 2001-05-16 |
IL148713A0 (en) | 2002-09-12 |
EP1084709A1 (en) | 2001-03-21 |
JP2003509469A (ja) | 2003-03-11 |
AP2002002445A0 (en) | 2002-03-31 |
EP1212083A1 (en) | 2002-06-12 |
OA12023A (en) | 2006-04-19 |
CA2383433A1 (en) | 2001-03-29 |
WO2001021200A1 (en) | 2001-03-29 |
CN1387442A (zh) | 2002-12-25 |
AU7433700A (en) | 2001-04-24 |
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