ZA200106738B - Hemocompatible surfaces and method for producing same. - Google Patents
Hemocompatible surfaces and method for producing same. Download PDFInfo
- Publication number
- ZA200106738B ZA200106738B ZA200106738A ZA200106738A ZA200106738B ZA 200106738 B ZA200106738 B ZA 200106738B ZA 200106738 A ZA200106738 A ZA 200106738A ZA 200106738 A ZA200106738 A ZA 200106738A ZA 200106738 B ZA200106738 B ZA 200106738B
- Authority
- ZA
- South Africa
- Prior art keywords
- materials
- hemocompatible
- blood
- cells
- constituents
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title description 5
- 239000000463 material Substances 0.000 claims abstract description 29
- 238000000034 method Methods 0.000 claims abstract description 16
- 239000008280 blood Substances 0.000 claims abstract description 15
- 210000004369 blood Anatomy 0.000 claims abstract description 14
- 210000000601 blood cell Anatomy 0.000 claims abstract description 9
- 210000001124 body fluid Anatomy 0.000 claims abstract description 9
- 239000010839 body fluid Substances 0.000 claims abstract description 9
- 210000005033 mesothelial cell Anatomy 0.000 claims abstract description 9
- 239000003814 drug Substances 0.000 claims abstract description 5
- 239000002537 cosmetic Substances 0.000 claims abstract description 4
- 230000036541 health Effects 0.000 claims abstract description 4
- 238000001356 surgical procedure Methods 0.000 claims abstract description 4
- 210000004027 cell Anatomy 0.000 claims description 14
- 239000000126 substance Substances 0.000 claims description 13
- 239000000470 constituent Substances 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 9
- 210000000056 organ Anatomy 0.000 claims description 6
- 150000002894 organic compounds Chemical class 0.000 claims description 6
- 210000001557 animal structure Anatomy 0.000 claims description 5
- 150000002484 inorganic compounds Chemical class 0.000 claims description 5
- 229910010272 inorganic material Inorganic materials 0.000 claims description 5
- 150000004676 glycans Chemical class 0.000 claims description 4
- 230000001453 nonthrombogenic effect Effects 0.000 claims description 4
- 229920001282 polysaccharide Polymers 0.000 claims description 4
- 239000005017 polysaccharide Substances 0.000 claims description 4
- 210000001519 tissue Anatomy 0.000 claims description 3
- 239000000956 alloy Substances 0.000 claims description 2
- 210000001772 blood platelet Anatomy 0.000 claims description 2
- 239000000919 ceramic Substances 0.000 claims description 2
- 239000011521 glass Substances 0.000 claims description 2
- 230000002163 immunogen Effects 0.000 claims description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- 229910044991 metal oxide Inorganic materials 0.000 claims description 2
- 150000004706 metal oxides Chemical class 0.000 claims description 2
- 150000002739 metals Chemical class 0.000 claims description 2
- 239000011707 mineral Substances 0.000 claims description 2
- 102000016611 Proteoglycans Human genes 0.000 claims 3
- 108010067787 Proteoglycans Proteins 0.000 claims 3
- 229920001542 oligosaccharide Polymers 0.000 claims 3
- 150000002482 oligosaccharides Chemical class 0.000 claims 3
- 229930186217 Glycolipid Natural products 0.000 claims 2
- 102000028180 Glycophorins Human genes 0.000 claims 2
- 108091005250 Glycophorins Proteins 0.000 claims 2
- 102000003886 Glycoproteins Human genes 0.000 claims 2
- 108090000288 Glycoproteins Proteins 0.000 claims 2
- 229920002971 Heparan sulfate Polymers 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 210000003743 erythrocyte Anatomy 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 229920001287 Chondroitin sulfate Polymers 0.000 claims 1
- 229920000045 Dermatan sulfate Polymers 0.000 claims 1
- 229920000288 Keratan sulfate Polymers 0.000 claims 1
- 229910045601 alloy Inorganic materials 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 229940107200 chondroitin sulfates Drugs 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 150000002339 glycosphingolipids Chemical class 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 210000002747 omentum Anatomy 0.000 claims 1
- 210000004303 peritoneum Anatomy 0.000 claims 1
- 230000023555 blood coagulation Effects 0.000 description 9
- 239000011248 coating agent Substances 0.000 description 6
- 238000000576 coating method Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 210000002889 endothelial cell Anatomy 0.000 description 6
- 239000007943 implant Substances 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 5
- 230000002965 anti-thrombogenic effect Effects 0.000 description 4
- 208000007536 Thrombosis Diseases 0.000 description 3
- 210000003709 heart valve Anatomy 0.000 description 3
- 230000008105 immune reaction Effects 0.000 description 3
- 239000004922 lacquer Substances 0.000 description 3
- 230000002792 vascular Effects 0.000 description 3
- 208000005189 Embolism Diseases 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 229940127219 anticoagulant drug Drugs 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 201000004384 Alopecia Diseases 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 229920003043 Cellulose fiber Polymers 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010017711 Gangrene Diseases 0.000 description 1
- 102000018697 Membrane Proteins Human genes 0.000 description 1
- 108010052285 Membrane Proteins Proteins 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229920003180 amino resin Polymers 0.000 description 1
- 239000012237 artificial material Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 208000024963 hair loss Diseases 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 230000002008 hemorrhagic effect Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229910001092 metal group alloy Inorganic materials 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920001568 phenolic resin Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- -1 polyethylenes Polymers 0.000 description 1
- 229920002959 polymer blend Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000003356 suture material Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 206010043554 thrombocytopenia Diseases 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/06—Use of macromolecular materials
- A61L33/12—Polypeptides, proteins or derivatives thereof, e.g. degradation products thereof
- A61L33/128—Other specific proteins or polypeptides not covered by A61L33/122 - A61L33/126
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/06—Use of macromolecular materials
- A61L33/08—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/18—Use of ingredients of undetermined constitution or reaction products thereof
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
- Saccharide Compounds (AREA)
- Dental Preparations (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19908318A DE19908318A1 (de) | 1999-02-26 | 1999-02-26 | Hämokompatible Oberflächen und Verfahren zu deren Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200106738B true ZA200106738B (en) | 2002-08-15 |
Family
ID=7898933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200106738A ZA200106738B (en) | 1999-02-26 | 2001-08-15 | Hemocompatible surfaces and method for producing same. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1152778B1 (fr) |
| JP (1) | JP3597474B2 (fr) |
| KR (1) | KR100503913B1 (fr) |
| CN (1) | CN1198660C (fr) |
| AT (1) | ATE250437T1 (fr) |
| AU (1) | AU758873B2 (fr) |
| BR (1) | BR0008968A (fr) |
| CA (1) | CA2363119C (fr) |
| DE (2) | DE19908318A1 (fr) |
| IL (1) | IL144912A (fr) |
| WO (1) | WO2000050106A2 (fr) |
| ZA (1) | ZA200106738B (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1568166A (zh) | 2001-10-15 | 2005-01-19 | 荷姆泰克股份有限公司 | 预防再狭窄的涂层支架 |
| AU2003243885B8 (en) | 2002-05-09 | 2009-08-06 | Hemoteq Ag | Medical products comprising a haemocompatible coating, production and use thereof |
| DE10329296B4 (de) * | 2003-06-24 | 2007-07-12 | Leibniz-Institut Für Polymerforschung Dresden E.V. | Beschichtungssystem für Biomaterialien |
| DE102005040211B4 (de) | 2005-08-16 | 2010-02-11 | Maquet Cardiopulmonary Ag | Verwendung von nichtionischen Estern in einer Beschichtung für mit Blut in Kontakt kommende Oberflächen und medizinische Vorrichtung |
| MX354144B (es) | 2006-07-03 | 2018-02-14 | Hemoteq Ag | Metodo, fabricacion y uso de productos medicos que liberan sustancia activa para mantener vasos sanguineos abiertos. |
| US8597720B2 (en) | 2007-01-21 | 2013-12-03 | Hemoteq Ag | Medical product for treating stenosis of body passages and for preventing threatening restenosis |
| US9192697B2 (en) | 2007-07-03 | 2015-11-24 | Hemoteq Ag | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis |
| EP2944332B1 (fr) | 2009-07-10 | 2016-08-17 | Boston Scientific Scimed, Inc. | Utilisation de nanocristaux pour un ballonnet de distribution de médicament |
| US10080821B2 (en) | 2009-07-17 | 2018-09-25 | Boston Scientific Scimed, Inc. | Nucleation of drug delivery balloons to provide improved crystal size and density |
| US8889211B2 (en) | 2010-09-02 | 2014-11-18 | Boston Scientific Scimed, Inc. | Coating process for drug delivery balloons using heat-induced rewrap memory |
| WO2013022458A1 (fr) | 2011-08-05 | 2013-02-14 | Boston Scientific Scimed, Inc. | Procédés de conversion d'une substance médicamenteuse amorphe en une forme cristalline |
| WO2013028208A1 (fr) | 2011-08-25 | 2013-02-28 | Boston Scientific Scimed, Inc. | Dispositif médical comprenant un revêtement médicamenteux cristallin |
| CN102501344B (zh) * | 2011-09-29 | 2014-07-16 | 华东交通大学 | 一种具有仿生周期结构的血液相容性材料表面的构建方法 |
| KR102223440B1 (ko) * | 2013-02-08 | 2021-03-05 | 아셀, 인크. | 세포외 기질 재료로부터의 생리활성 겔의 제조 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4350629A (en) * | 1981-07-29 | 1982-09-21 | Massachusetts Institute Of Technology | Procedures for preparing composite materials from collagen and glycosaminoglycan |
| DE3639561A1 (de) * | 1986-11-20 | 1988-06-01 | Baumann Hanno | Verfahren zur herstellung von nicht-thrombogenen substraten |
| US5236835A (en) * | 1988-10-05 | 1993-08-17 | Hapgood, C.V. | Electro insertion of proteins into red cell membranes |
| US5043164A (en) * | 1989-01-17 | 1991-08-27 | The University Of Tennessee Research Corporation | Blood-stable, cholesterol-free liposomes |
| GB9116036D0 (en) * | 1991-07-25 | 1991-09-11 | Univ Leicester | Preparing grafts for implantation |
| DE4402064A1 (de) * | 1994-01-25 | 1995-07-27 | Kohlensaeurewerk Deutschland | Verfahren zur Bekämpfung von Schädlingen in Schüttgut |
| US5643712A (en) * | 1994-05-20 | 1997-07-01 | Brasile; Lauren | Method for treating and rendering grafts nonthrombogenic and substantially nonimmunogenic using an extracellular matrix coating |
| DE19505070C2 (de) * | 1995-02-15 | 1997-03-27 | Axel Prof Dr Med Haverich | Künstliche Gefäßsysteme und Verfahren zu ihrer Herstellung |
| DE19648876C2 (de) * | 1996-11-16 | 1999-10-07 | Will Minuth | Verfahren zum Herstellen eines natürlichen Implantats |
| DE19700078A1 (de) * | 1997-01-03 | 1998-07-09 | Huels Chemische Werke Ag | Herstellung von polymeren Materialien mit zellproliferationsbegünstigenden Eigenschaften |
| DE19706667A1 (de) * | 1997-02-20 | 1998-08-27 | Merck Patent Gmbh | Knochenersatzmaterial mit einer Oberflächenbelegung mit Peptiden mit RGD-Aminosäuresequenz |
| DE19724869C2 (de) * | 1997-06-12 | 1999-05-12 | Henkel Kgaa | Verwendung von Citosanderivaten zur Oberflächenbeschichtung |
-
1999
- 1999-02-26 DE DE19908318A patent/DE19908318A1/de not_active Withdrawn
-
2000
- 2000-02-24 BR BR0008968-0A patent/BR0008968A/pt not_active Application Discontinuation
- 2000-02-24 EP EP00922483A patent/EP1152778B1/fr not_active Expired - Lifetime
- 2000-02-24 AU AU42871/00A patent/AU758873B2/en not_active Ceased
- 2000-02-24 DE DE50003828T patent/DE50003828D1/de not_active Expired - Fee Related
- 2000-02-24 AT AT00922483T patent/ATE250437T1/de not_active IP Right Cessation
- 2000-02-24 WO PCT/EP2000/001497 patent/WO2000050106A2/fr active IP Right Grant
- 2000-02-24 CA CA002363119A patent/CA2363119C/fr not_active Expired - Fee Related
- 2000-02-24 JP JP2000600716A patent/JP3597474B2/ja not_active Expired - Fee Related
- 2000-02-24 KR KR10-2001-7010550A patent/KR100503913B1/ko not_active IP Right Cessation
- 2000-02-24 CN CNB008042330A patent/CN1198660C/zh not_active Expired - Fee Related
-
2001
- 2001-08-15 ZA ZA200106738A patent/ZA200106738B/en unknown
- 2001-08-15 IL IL144912A patent/IL144912A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2363119A1 (fr) | 2000-08-31 |
| KR100503913B1 (ko) | 2005-07-26 |
| DE50003828D1 (de) | 2003-10-30 |
| JP2002537075A (ja) | 2002-11-05 |
| JP3597474B2 (ja) | 2004-12-08 |
| CA2363119C (fr) | 2007-04-10 |
| DE19908318A1 (de) | 2000-08-31 |
| IL144912A (en) | 2009-09-22 |
| IL144912A0 (en) | 2002-06-30 |
| CN1341033A (zh) | 2002-03-20 |
| CN1198660C (zh) | 2005-04-27 |
| AU758873B2 (en) | 2003-04-03 |
| AU4287100A (en) | 2000-09-14 |
| WO2000050106A3 (fr) | 2001-04-26 |
| BR0008968A (pt) | 2001-11-27 |
| KR20010104343A (ko) | 2001-11-24 |
| EP1152778B1 (fr) | 2003-09-24 |
| WO2000050106A2 (fr) | 2000-08-31 |
| EP1152778A1 (fr) | 2001-11-14 |
| ATE250437T1 (de) | 2003-10-15 |
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