ZA200103669B - Hypoxia-inducible factor 1a HIF-1α variants and methods for identifying HIF-1α modulators. - Google Patents
Hypoxia-inducible factor 1a HIF-1α variants and methods for identifying HIF-1α modulators. Download PDFInfo
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
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- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Testing, Inspecting, Measuring Of Stereoscopic Televisions And Televisions (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Radar Systems Or Details Thereof (AREA)
- Amplifiers (AREA)
- Semiconductor Lasers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9803891A SE9803891D0 (sv) | 1998-11-13 | 1998-11-13 | Protein Variants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200103669B true ZA200103669B (en) | 2002-05-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ZA200103669A ZA200103669B (en) | 1998-11-13 | 2001-05-07 | Hypoxia-inducible factor 1a HIF-1α variants and methods for identifying HIF-1α modulators. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1141005B1 (xx) |
| JP (1) | JP2002530063A (xx) |
| KR (1) | KR100648761B1 (xx) |
| CN (1) | CN1330666C (xx) |
| AT (1) | ATE374210T1 (xx) |
| AU (1) | AU761594B2 (xx) |
| BR (1) | BR9915263A (xx) |
| CA (1) | CA2350830A1 (xx) |
| DE (1) | DE69937199D1 (xx) |
| HK (1) | HK1043372B (xx) |
| NZ (1) | NZ511450A (xx) |
| SE (1) | SE9803891D0 (xx) |
| TR (1) | TR200101345T2 (xx) |
| WO (1) | WO2000029437A1 (xx) |
| ZA (1) | ZA200103669B (xx) |
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| GB9911047D0 (en) * | 1999-05-12 | 1999-07-14 | Isis Innovation | Assay method and means |
| WO2000074725A1 (en) * | 1999-06-04 | 2000-12-14 | Dana-Farber Cancer Institute, Inc. | Identification of compounds that modify transcriptional responses to hypoxia |
| AU2001265039B2 (en) | 2000-05-26 | 2007-03-29 | Board Of Trustees Of The University Of Illinois | Reagents and methods for identifying and modulating expression of genes regulated by retinoids |
| AU2001290179B2 (en) * | 2000-08-07 | 2007-07-12 | Angiogenetics Sweden Ab | Mechanism of conditional regulation of the hypoxia-inducible factor-1 by the von hippel-lindau tumor suppressor protein |
| US20030045830A1 (en) * | 2001-04-17 | 2003-03-06 | De Bizemont Therese | Gene therapy with chimeric oligonucleotides delivered by a method comprising a step of iontophoresis |
| EP1842856A3 (en) * | 2001-05-23 | 2007-12-12 | Angiogene Inc. | Hypoxia inducing factors and uses thereof for inducing angiogenesis and improving muscular functions |
| EP1395609A2 (en) | 2001-05-23 | 2004-03-10 | Angiogene Inc. | Hypoxia inducible factors and uses thereof for inducing angiogenesis and improving muscular functions |
| AU2003201798A1 (en) * | 2002-01-11 | 2003-09-02 | Angio Genetics Sweden Ab | Hif-1 alpha proteins mutated in the c-terminal transactivation domain |
| CN100366747C (zh) * | 2005-03-08 | 2008-02-06 | 上海第二医科大学附属仁济医院 | 低氧诱导因子小干扰rna质粒 |
| CN100418574C (zh) * | 2005-10-26 | 2008-09-17 | 王成球 | 一类封闭人类HIF-1α基因和调控网络中下游相关基因的染色质肽 |
| CN102127161B (zh) * | 2010-12-16 | 2013-03-27 | 何明忠 | 抗肿瘤多肽及其用途 |
| CN106366173A (zh) * | 2015-07-24 | 2017-02-01 | 北京京爱康科技有限公司 | 一种通过结合低氧反应元件控制缺氧反应基因表达的染色质肽 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5882914A (en) * | 1995-06-06 | 1999-03-16 | The Johns Hopkins University School Of Medicine | Nucleic acids encoding the hypoxia inducible factor-1 |
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1998
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1999
- 1999-11-11 NZ NZ511450A patent/NZ511450A/en unknown
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- 1999-11-11 CA CA002350830A patent/CA2350830A1/en not_active Abandoned
- 1999-11-11 EP EP99958594A patent/EP1141005B1/en not_active Expired - Lifetime
- 1999-11-11 TR TR2001/01345T patent/TR200101345T2/xx unknown
- 1999-11-11 DE DE69937199T patent/DE69937199D1/de not_active Expired - Lifetime
- 1999-11-11 JP JP2000582422A patent/JP2002530063A/ja active Pending
- 1999-11-11 AU AU15931/00A patent/AU761594B2/en not_active Ceased
- 1999-11-11 AT AT99958594T patent/ATE374210T1/de not_active IP Right Cessation
- 1999-11-11 CN CNB99814388XA patent/CN1330666C/zh not_active Expired - Fee Related
- 1999-11-11 WO PCT/SE1999/002053 patent/WO2000029437A1/en active IP Right Grant
- 1999-11-11 KR KR1020017005928A patent/KR100648761B1/ko not_active IP Right Cessation
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2001
- 2001-05-07 ZA ZA200103669A patent/ZA200103669B/en unknown
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2002
- 2002-07-09 HK HK02105080.8A patent/HK1043372B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1593100A (en) | 2000-06-05 |
| EP1141005B1 (en) | 2007-09-26 |
| KR20010080411A (ko) | 2001-08-22 |
| EP1141005A1 (en) | 2001-10-10 |
| WO2000029437A1 (en) | 2000-05-25 |
| JP2002530063A (ja) | 2002-09-17 |
| TR200101345T2 (tr) | 2001-10-22 |
| DE69937199D1 (de) | 2007-11-08 |
| AU761594B2 (en) | 2003-06-05 |
| HK1043372A1 (en) | 2002-09-13 |
| BR9915263A (pt) | 2001-10-30 |
| SE9803891D0 (sv) | 1998-11-13 |
| KR100648761B1 (ko) | 2006-11-23 |
| HK1043372B (zh) | 2008-05-09 |
| CA2350830A1 (en) | 2000-05-25 |
| ATE374210T1 (de) | 2007-10-15 |
| NZ511450A (en) | 2003-08-29 |
| CN1330666C (zh) | 2007-08-08 |
| CN1330663A (zh) | 2002-01-09 |
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