ZA200102730B - Method of treating thrombocytopenic purpura and hemolytic uremic syndrome. - Google Patents

Method of treating thrombocytopenic purpura and hemolytic uremic syndrome. Download PDF

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Publication number
ZA200102730B
ZA200102730B ZA200102730A ZA200102730A ZA200102730B ZA 200102730 B ZA200102730 B ZA 200102730B ZA 200102730 A ZA200102730 A ZA 200102730A ZA 200102730 A ZA200102730 A ZA 200102730A ZA 200102730 B ZA200102730 B ZA 200102730B
Authority
ZA
South Africa
Prior art keywords
protein
activated protein
substance
composition
administered
Prior art date
Application number
ZA200102730A
Other languages
English (en)
Inventor
Charles Jack Fisher
Sau-Chi Betty Yan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA200102730B publication Critical patent/ZA200102730B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4866Protein C (3.4.21.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
  • Enzymes And Modification Thereof (AREA)
ZA200102730A 1998-12-10 2001-04-03 Method of treating thrombocytopenic purpura and hemolytic uremic syndrome. ZA200102730B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11177098P 1998-12-10 1998-12-10

Publications (1)

Publication Number Publication Date
ZA200102730B true ZA200102730B (en) 2002-07-03

Family

ID=22340356

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200102730A ZA200102730B (en) 1998-12-10 2001-04-03 Method of treating thrombocytopenic purpura and hemolytic uremic syndrome.

Country Status (13)

Country Link
US (2) US20010003740A1 (ja)
EP (1) EP1137432B1 (ja)
JP (1) JP2002531519A (ja)
CN (1) CN1329503A (ja)
AT (1) ATE264113T1 (ja)
AU (1) AU1838500A (ja)
BR (1) BR9915984A (ja)
CA (1) CA2351555A1 (ja)
DE (1) DE69916493T2 (ja)
ES (1) ES2219094T3 (ja)
IL (1) IL142249A0 (ja)
WO (1) WO2000033867A1 (ja)
ZA (1) ZA200102730B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001292308A1 (en) * 2000-09-30 2002-04-15 Mochida Pharmaceutical Co., Ltd. Preventives/remedies for hemolytic anemia
CA2668187A1 (en) * 2006-10-31 2008-06-19 The Scripps Research Institute Dosing regimen of activated protein c and variants having reduced anticoagulant activity
CN111035754A (zh) * 2016-03-23 2020-04-21 兆科药业(合肥)有限公司 抗血小板溶栓素在制备治疗血栓性血小板减少性紫癜的药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516650A (en) * 1985-06-27 1996-05-14 Zymogenetics, Inc. Production of activated protein C
CA2288143C (en) * 1997-04-28 2012-08-21 Eli Lilly And Company Activated protein c formulations

Also Published As

Publication number Publication date
BR9915984A (pt) 2001-09-04
AU1838500A (en) 2000-06-26
US20010003740A1 (en) 2001-06-14
WO2000033867A1 (en) 2000-06-15
EP1137432B1 (en) 2004-04-14
EP1137432A1 (en) 2001-10-04
CA2351555A1 (en) 2000-06-15
DE69916493T2 (de) 2005-03-24
US20040087643A1 (en) 2004-05-06
JP2002531519A (ja) 2002-09-24
IL142249A0 (en) 2002-03-10
CN1329503A (zh) 2002-01-02
ES2219094T3 (es) 2004-11-16
ATE264113T1 (de) 2004-04-15
DE69916493D1 (de) 2004-05-19

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