ZA200102380B - Methods and compositions for inhibiting neoplastic cell growth. - Google Patents

Methods and compositions for inhibiting neoplastic cell growth. Download PDF

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Publication number
ZA200102380B
ZA200102380B ZA200102380A ZA200102380A ZA200102380B ZA 200102380 B ZA200102380 B ZA 200102380B ZA 200102380 A ZA200102380 A ZA 200102380A ZA 200102380 A ZA200102380 A ZA 200102380A ZA 200102380 B ZA200102380 B ZA 200102380B
Authority
ZA
South Africa
Prior art keywords
amino acid
seq
acid sequence
polypeptide
pro172
Prior art date
Application number
ZA200102380A
Other languages
English (en)
Inventor
Avi Ashkenazi
Audrey Goddard
Austin L Gurney
Robert D Klein
Mary Napier
William I Wood
Jean Yuan
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ZA200102380B publication Critical patent/ZA200102380B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200102380A 1998-10-13 1999-10-05 Methods and compositions for inhibiting neoplastic cell growth. ZA200102380B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10408098P 1998-10-13 1998-10-13

Publications (1)

Publication Number Publication Date
ZA200102380B true ZA200102380B (en) 2002-03-22

Family

ID=22298575

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200102380A ZA200102380B (en) 1998-10-13 1999-10-05 Methods and compositions for inhibiting neoplastic cell growth.

Country Status (15)

Country Link
EP (1) EP1121439B1 (xx)
JP (1) JP2002527452A (xx)
KR (2) KR100448426B1 (xx)
AT (2) ATE332970T1 (xx)
AU (1) AU758462B2 (xx)
CA (1) CA2344465A1 (xx)
DE (2) DE69932342T2 (xx)
DK (2) DK1518930T3 (xx)
ES (2) ES2268901T3 (xx)
IL (3) IL142088A0 (xx)
MX (1) MXPA01003636A (xx)
NZ (1) NZ510584A (xx)
PT (2) PT1121439E (xx)
WO (1) WO2000021996A2 (xx)
ZA (1) ZA200102380B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7169906B2 (en) 1997-09-17 2007-01-30 Genentech, Inc. PRO211 polypeptides
US6974689B1 (en) 1997-09-18 2005-12-13 Genentech, Inc. Nucleic acid encoding PRO211 polypeptides
CN1633498A (zh) * 2000-04-21 2005-06-29 武田药品工业株式会社 新型胰岛素/胰岛素样生长因子/松弛素家族多肽及其dna
JP2011507922A (ja) * 2007-12-28 2011-03-10 バイオインヴェント インターナショナル アーベー 配合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ226799A (en) * 1987-11-06 1991-08-27 Oncogen Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor
US5814307A (en) * 1989-04-10 1998-09-29 Bristol-Myers Squibb Company Method for regulating cell growth, leukocyte differentiation and tumor cell growth using Oncostatin M to stimulate synthesis of IL-6
US5416192A (en) * 1990-04-03 1995-05-16 Bristol-Myers Squibb Company Epithelins: novel cysteine-rich growth modulating proteins
WO1999014327A2 (en) * 1997-09-17 1999-03-25 Genentech, Inc. Genes amplified in tumours, antibodies against the proteins coded thereby, and their use in diagnosis and treatment of cancer
ATE447583T1 (de) * 1997-09-17 2009-11-15 Genentech Inc Polypeptide und dafür kodierende nukleinsäure

Also Published As

Publication number Publication date
IL189502A0 (en) 2008-06-05
ES2268901T3 (es) 2007-03-16
KR20030096387A (ko) 2003-12-24
KR20010085915A (ko) 2001-09-07
KR100448427B1 (ko) 2004-09-16
CA2344465A1 (en) 2000-04-20
IL142088A (en) 2008-11-26
ATE363536T1 (de) 2007-06-15
DE69932342D1 (de) 2006-08-24
DK1518930T3 (da) 2007-10-01
KR100448426B1 (ko) 2004-09-13
DE69932342T2 (de) 2007-07-12
PT1518930E (pt) 2007-09-04
ES2290606T3 (es) 2008-02-16
EP1121439A2 (en) 2001-08-08
ATE332970T1 (de) 2006-08-15
AU758462B2 (en) 2003-03-20
PT1121439E (pt) 2006-12-29
WO2000021996A2 (en) 2000-04-20
DE69936234D1 (de) 2007-07-12
DK1121439T3 (da) 2006-11-13
MXPA01003636A (es) 2003-10-14
JP2002527452A (ja) 2002-08-27
WO2000021996A3 (en) 2000-11-09
AU1200500A (en) 2000-05-01
DE69936234T2 (de) 2008-03-06
EP1121439B1 (en) 2006-07-12
IL142088A0 (en) 2002-03-10
NZ510584A (en) 2003-04-29

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