YU59502A - Dobijanje dialkilpiridilborana - Google Patents

Dobijanje dialkilpiridilborana

Info

Publication number
YU59502A
YU59502A YU59502A YUP59502A YU59502A YU 59502 A YU59502 A YU 59502A YU 59502 A YU59502 A YU 59502A YU P59502 A YUP59502 A YU P59502A YU 59502 A YU59502 A YU 59502A
Authority
YU
Yugoslavia
Prior art keywords
preparation
threealkylborane
greenyard
reagent
dialkylpyridylboranes
Prior art date
Application number
YU59502A
Other languages
English (en)
Inventor
David Harold Brown Ripin
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of YU59502A publication Critical patent/YU59502A/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/027Organoboranes and organoborohydrides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Ovaj pronalazak se odnosi na postupke dobijanja dialkilpiridilborana, reagovanjem Grinjardovog piridinskog reagensa sa alkoksidialkilboranom ili trialkilboranom. Reakcija se može odigrati na temperaturama u rasponu od oko 0В°C do oko 40В°C. Grinjardov piridinski reagens se može napraviti in situ reakcijom Grinjardovog reagensa (RMgX) sa halopiridinom u pogodnom rastvaraču, kao što je tetrahidrofuran, nakon čega sledi dodavanje alkoksidialkilborana ili trialkilborana kako bi se doblo dialkilpiridilboran.[This invention refers to the procedures for preparation of dialkylpyridinylboranes, by reaction of Greenyard's pyridine reagent with alcoxydialkylbicarborane or threealkylborane. Chemical reaction takes place even at the temperature ranges from about 0В°C to about 40В°C. Greenyard's reagent (RMgX) with halopyridine in the adequate solvent, as with tetrahidrofyrane, and upon comes addition of the alcoxydialkylborane or threealkylborane so as to obtain dialkylpyridilborane.
YU59502A 2001-08-27 2002-08-09 Dobijanje dialkilpiridilborana YU59502A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31518301P 2001-08-27 2001-08-27

Publications (1)

Publication Number Publication Date
YU59502A true YU59502A (sh) 2004-12-31

Family

ID=23223262

Family Applications (1)

Application Number Title Priority Date Filing Date
YU59502A YU59502A (sh) 2001-08-27 2002-08-09 Dobijanje dialkilpiridilborana

Country Status (18)

Country Link
US (1) US6570017B2 (sh)
EP (1) EP1288217B1 (sh)
JP (1) JP2003096084A (sh)
KR (1) KR20030019112A (sh)
CN (1) CN1401649A (sh)
AT (1) ATE321766T1 (sh)
BR (1) BR0203371A (sh)
CA (1) CA2399834C (sh)
CZ (1) CZ20022642A3 (sh)
DE (1) DE60210224T2 (sh)
ES (1) ES2256416T3 (sh)
HU (1) HUP0202868A3 (sh)
IL (1) IL151379A0 (sh)
MX (1) MXPA02008364A (sh)
PL (1) PL355706A1 (sh)
RU (1) RU2002122947A (sh)
YU (1) YU59502A (sh)
ZA (1) ZA200206778B (sh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8648192B2 (en) * 2010-05-26 2014-02-11 Boehringer Ingelheim International Gmbh 2-oxo-1,2-dihydropyridin-4-ylboronic acid derivatives
CN103483366B (zh) * 2013-09-05 2017-02-08 润泽制药(苏州)有限公司 甲氧基二乙基硼烷的制备方法
JP6898340B2 (ja) * 2015-11-17 2021-07-07 コルテバ アグリサイエンス エルエルシー 4−((6−(2−(2,4−ジフルオロフェニル)−1,1−ジフルオロ−2−ヒドロキシ−3−(1h−1,2,4−トリアゾール−1−イル)プロピル)ピリジン−3−イル)オキシ)ベンゾニトリル及び調製方法
CN117402184B (zh) * 2023-12-15 2024-04-26 山东国邦药业有限公司 一种二乙基甲氧基硼烷的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0010947B1 (en) * 1978-11-07 1982-01-13 Imperial Chemical Industries Plc Alkylborane complexes with aromatic amines, solutions thereof for use as hydroborating and reducing agents, and processes for their manufacture
GB8304613D0 (en) * 1983-02-18 1983-03-23 Ici Plc Chemical process
DE4320432A1 (de) * 1993-06-21 1994-12-22 Bayer Ag Substituierte Mono- und Bipyridylmethylderivate
US5486534A (en) * 1994-07-21 1996-01-23 G. D. Searle & Co. 3,4-substituted pyrazoles for the treatment of inflammation
CA2329065A1 (en) * 1998-05-05 1999-11-11 Francisco Xavier Talamas Pyrazole derivatives as p-38 map kinase inhibitors

Also Published As

Publication number Publication date
HUP0202868A3 (en) 2004-04-28
PL355706A1 (en) 2003-03-10
CA2399834C (en) 2006-08-22
HU0202868D0 (sh) 2002-10-28
CA2399834A1 (en) 2003-02-27
EP1288217A3 (en) 2003-09-17
EP1288217B1 (en) 2006-03-29
RU2002122947A (ru) 2004-03-10
ATE321766T1 (de) 2006-04-15
CN1401649A (zh) 2003-03-12
US6570017B2 (en) 2003-05-27
US20030083312A1 (en) 2003-05-01
KR20030019112A (ko) 2003-03-06
ES2256416T3 (es) 2006-07-16
DE60210224D1 (de) 2006-05-18
ZA200206778B (en) 2004-02-23
JP2003096084A (ja) 2003-04-03
EP1288217A2 (en) 2003-03-05
DE60210224T2 (de) 2007-01-11
IL151379A0 (en) 2003-04-10
HUP0202868A2 (hu) 2003-06-28
MXPA02008364A (es) 2003-03-04
BR0203371A (pt) 2003-05-27
CZ20022642A3 (cs) 2003-09-17

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