YU48633B - Postupak za dobijanje vodenog rastvora nitroglicerinskog hidrofilnog preparata za raspršivanje pumpicom - Google Patents

Postupak za dobijanje vodenog rastvora nitroglicerinskog hidrofilnog preparata za raspršivanje pumpicom

Info

Publication number
YU48633B
YU48633B YU121591A YU121591A YU48633B YU 48633 B YU48633 B YU 48633B YU 121591 A YU121591 A YU 121591A YU 121591 A YU121591 A YU 121591A YU 48633 B YU48633 B YU 48633B
Authority
YU
Yugoslavia
Prior art keywords
composition containing
spray composition
pump spray
hydrophilic aqueous
containing nitroglycerin
Prior art date
Application number
YU121591A
Other languages
English (en)
Other versions
YU121591A (sh
Inventor
Karin Dr. Klokkers-Bethke
Ulrich dr. Munch
Original Assignee
Schwarz Pharma Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schwarz Pharma Ag. filed Critical Schwarz Pharma Ag.
Priority to SI9111215A priority Critical patent/SI9111215A/sl
Priority to HRP-1215/91A priority patent/HRP920988B1/xx
Publication of YU121591A publication Critical patent/YU121591A/sh
Publication of YU48633B publication Critical patent/YU48633B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Postupak za dobijanje vodenog rastvora nitroglicerinskog hidrofilnog preparata za raspršivanje pumpicom, koji pored nitroglicerina sadrži i jednu ili više uobičajenih pomoćnih supstanci, naznačen time, što se pomeša 0,15-0,50 mas.% nitroglicerina, 24,50-24,85 mas.% etanola, 32,00 mas.% 1,2-propilenglikola i 43,00 mas.% prečišćene vode, dobijeni rastvor podesi na pH 3-6 i napuni u pogodno primarno sredstvo za pakovanje. - Prijava sadrži još 2 zavisna zahteva.
YU121591A 1990-08-17 1991-07-10 Postupak za dobijanje vodenog rastvora nitroglicerinskog hidrofilnog preparata za raspršivanje pumpicom YU48633B (sh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI9111215A SI9111215A (en) 1990-08-17 1991-07-10 Hydrophilous, water pump spray comprising nitroglycerin
HRP-1215/91A HRP920988B1 (en) 1990-08-17 1992-10-02 Nitroglicerinic, hydrophyl, water pump spray

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4026072A DE4026072A1 (de) 1990-08-17 1990-08-17 Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray

Publications (2)

Publication Number Publication Date
YU121591A YU121591A (sh) 1994-01-20
YU48633B true YU48633B (sh) 1999-03-04

Family

ID=6412426

Family Applications (1)

Application Number Title Priority Date Filing Date
YU121591A YU48633B (sh) 1990-08-17 1991-07-10 Postupak za dobijanje vodenog rastvora nitroglicerinskog hidrofilnog preparata za raspršivanje pumpicom

Country Status (18)

Country Link
US (1) US5744124A (sh)
EP (1) EP0471161B1 (sh)
JP (1) JPH0818981B2 (sh)
AT (1) ATE110567T1 (sh)
BG (1) BG60852B1 (sh)
CZ (1) CZ280490B6 (sh)
DE (1) DE4026072A1 (sh)
DK (1) DK0471161T3 (sh)
ES (1) ES2060248T3 (sh)
FI (1) FI102873B (sh)
HR (1) HRP920988B1 (sh)
HU (1) HU206615B (sh)
IE (1) IE65273B1 (sh)
PT (1) PT98658B (sh)
RU (1) RU2060733C1 (sh)
SI (1) SI9111215A (sh)
SK (1) SK279132B6 (sh)
YU (1) YU48633B (sh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
US20030190286A1 (en) * 1997-10-01 2003-10-09 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma
DE69738333T2 (de) * 1997-10-01 2008-11-27 Novadel Pharma Inc. Nichtpolares Spray zur bukkalen Verabreichung
US7632517B2 (en) 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US20030185761A1 (en) 1997-10-01 2003-10-02 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20040136914A1 (en) 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing ondansetron
US20030077227A1 (en) 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20030072717A1 (en) * 2001-02-23 2003-04-17 Vapotronics, Inc. Inhalation device having an optimized air flow path
DE60213228T2 (de) * 2001-05-21 2007-06-21 Injet Digital Aerosols Ltd., North Ryde Zusammensetzungen für die freisetzung von protein auf dem pulmonalen weg
GB0417675D0 (en) * 2004-08-09 2004-09-08 Futura Medical Dev Ltd Composition for promoting vascular smooth muscle relaxation
GB0602224D0 (en) * 2006-02-03 2006-03-15 Futura Medical Dev Ltd Composition for promoting vascular smooth muscle relaxation
US20100184870A1 (en) * 2008-03-14 2010-07-22 Rolf Groteluschen Long-term stable pharmaceutical preparation containing the active ingredient glycerol trinitrate
DE202008007318U1 (de) 2008-03-14 2008-07-31 G. Pohl-Boskamp Gmbh & Co. Kg Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat
CA2806636C (en) 2010-08-03 2018-01-23 G. Pohl-Boskamp Gmbh & Co. Kg Use of glyceryl trinitrate for treating traumatic edema
CA2827714A1 (en) 2011-02-25 2012-08-30 G. Pohl-Boskamp Gmbh & Co. Kg Packaging of solid pharmaceutical preparations containing the active substance glyceryl trinitrate
HUE033092T2 (hu) 2012-05-31 2017-11-28 G Pohl-Boskamp Gmbh & Co Kg Arteriogenezis indukálása nitroglicerinnel mint nitrogén-oxid donorral
US9248099B2 (en) 2012-05-31 2016-02-02 Desmoid Aktiengesellschaft Use of stabilized granules containing glyceryl trinitrate for arteriogenesis
EP2878310B1 (en) 2013-11-29 2017-01-11 G. Pohl-Boskamp GmbH & Co. KG Sprayable aqueous composition comprising glyceryl trinitrate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE632504A (sh) * 1962-05-24
JPS599539B2 (ja) * 1979-11-13 1984-03-03 日本化薬株式会社 ニトログリセリン水溶液及びその製造法
DE3246081A1 (de) * 1982-12-13 1984-06-14 G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt Nitroglycerin-spray
DE3613187A1 (de) * 1986-04-18 1987-10-22 Mack Chem Pharm Verwendung einer carbonsaeure in zur topischen anwendung bestimmten pharmazeutischen zubereitungen
JPH0645538B2 (ja) * 1987-09-30 1994-06-15 日本化薬株式会社 ニトログリセリンスプレー剤
HU199678B (en) * 1988-07-08 1990-03-28 Egyt Gyogyszervegyeszeti Gyar Process for producing aerosols containing nitroglicerol
DE4018919C2 (de) * 1990-06-13 1994-08-25 Sanol Arznei Schwarz Gmbh Nitroglycerin-Spray

Also Published As

Publication number Publication date
HU912300D0 (en) 1991-12-30
HU206615B (en) 1992-12-28
JPH0818981B2 (ja) 1996-02-28
FI913882A0 (fi) 1991-08-16
HRP920988A2 (en) 1996-10-31
CS209991A3 (en) 1992-02-19
FI102873B1 (fi) 1999-03-15
JPH04230627A (ja) 1992-08-19
SK279132B6 (sk) 1998-07-08
HRP920988B1 (en) 1998-10-31
YU121591A (sh) 1994-01-20
IE65273B1 (en) 1995-10-18
US5744124A (en) 1998-04-28
DE4026072C2 (sh) 1992-05-21
IE912509A1 (en) 1992-02-26
EP0471161A1 (de) 1992-02-19
CZ280490B6 (cs) 1996-01-17
ES2060248T3 (es) 1994-11-16
DE4026072A1 (de) 1992-02-20
ATE110567T1 (de) 1994-09-15
FI102873B (fi) 1999-03-15
RU2060733C1 (ru) 1996-05-27
BG60852B1 (bg) 1996-05-31
EP0471161B1 (de) 1994-08-31
HUT59308A (en) 1992-05-28
PT98658A (pt) 1992-06-30
SI9111215A (en) 1995-08-31
FI913882A (fi) 1992-02-18
PT98658B (pt) 1999-01-29
DK0471161T3 (da) 1994-10-03

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