YU47694B - Novi derivati 1,8-benzonaftiridina, postupak za njihovo dobivanje i postupak za dobivanje farmaceutske smeše - Google Patents

Novi derivati 1,8-benzonaftiridina, postupak za njihovo dobivanje i postupak za dobivanje farmaceutske smeše

Info

Publication number
YU47694B
YU47694B YU205390A YU205390A YU47694B YU 47694 B YU47694 B YU 47694B YU 205390 A YU205390 A YU 205390A YU 205390 A YU205390 A YU 205390A YU 47694 B YU47694 B YU 47694B
Authority
YU
Yugoslavia
Prior art keywords
hydroxyalkyl
denotes
alkyl
radical
procedure
Prior art date
Application number
YU205390A
Other languages
English (en)
Other versions
YU205390A (sh
Inventor
M. Antoine
M. Barreau
J.-F. Desconclois
P. Girard
G. Picaut
Original Assignee
Laboratoire Roger Bellon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8914203A external-priority patent/FR2653663A1/fr
Priority claimed from FR9008757A external-priority patent/FR2664595B1/fr
Application filed by Laboratoire Roger Bellon filed Critical Laboratoire Roger Bellon
Publication of YU205390A publication Critical patent/YU205390A/sh
Publication of YU47694B publication Critical patent/YU47694B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Novi derivat 1,8-benzo/naftiridina, naznačen time, što odgovara opštoj formuli: u kojoj - R1 označava atom vodonika ili radikal hidroksi ili alkil, - R2 označava atom vodonika ili radikal alkil, fluoralkil, cikloalkil koji sadrži 3 do 6 atoma ugljenika, alkiloksi ili alkilamino, - R3 označava radikal fenil ili finilalkil po želji supstituisan sa jednim ili više atoma halogena ili radikala alkil, cikloalkil koji sadrži 3 do 6 atoma ugljenika, alkiloksi, cijan, amino, alkilamino, dialkilamino, alkiloksialkil, hidroksialkil, hidroksialkiloksi, metilendioksi, aminoalkil, alkilaminoalkil, ili dialkilaminoalkil čiji alkil-delovi mogu sa atomom azota za koji su vezani da formiraju heterociklični prsten sa 5 ili 6 članova, ili označava radikal heterociklil sa 5 članova koji sadrži 1 ili 2 heteroatoma odabrana između azota, kiseonika ili sumpora, a - R4 označava atom vodonika ili atom fluora, i čiji su alkil radikali račvasti ili neračvasti i sadrže 1 do 4 atoma ugljenika, u svojim izomernim oblicima ili njihovim smešama kao i u obliku svojih farmaceutski prihvatljivih metalnih soli, adicionih soli sa azotnim bazama i adicionih soli sa kiselinama, i u obliku hidrata. Prijava sadrži još 3 nezavisna i 6 zavisnih zahteva.
YU205390A 1989-10-30 1990-10-30 Novi derivati 1,8-benzonaftiridina, postupak za njihovo dobivanje i postupak za dobivanje farmaceutske smeše YU47694B (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8914203A FR2653663A1 (en) 1989-10-30 1989-10-30 Novel benzo[1,8]naphthyridine derivatives, their preparation and compositions containing them
FR9008757A FR2664595B1 (fr) 1990-07-10 1990-07-10 Nouveaux derives de benzonaphtyridine-1,8, leur preparation et les compositions qui les contiennent.

Publications (2)

Publication Number Publication Date
YU205390A YU205390A (sh) 1992-09-07
YU47694B true YU47694B (sh) 1996-01-08

Family

ID=26227626

Family Applications (1)

Application Number Title Priority Date Filing Date
YU205390A YU47694B (sh) 1989-10-30 1990-10-30 Novi derivati 1,8-benzonaftiridina, postupak za njihovo dobivanje i postupak za dobivanje farmaceutske smeše

Country Status (24)

Country Link
US (1) US5053509A (sh)
EP (1) EP0431991B1 (sh)
JP (1) JPH03151384A (sh)
KR (1) KR910007928A (sh)
AT (1) ATE100103T1 (sh)
AU (1) AU629997B2 (sh)
BG (1) BG60915B1 (sh)
CA (1) CA2028730A1 (sh)
CZ (1) CZ280513B6 (sh)
DE (1) DE69005994T2 (sh)
DK (1) DK0431991T3 (sh)
ES (1) ES2062455T3 (sh)
FI (1) FI92068C (sh)
HU (1) HU208138B (sh)
IE (1) IE65099B1 (sh)
IL (1) IL96159A (sh)
NO (1) NO175433C (sh)
NZ (1) NZ235890A (sh)
PL (1) PL164270B1 (sh)
PT (1) PT95743B (sh)
RO (1) RO108347B1 (sh)
RU (1) RU2047613C1 (sh)
TW (1) TW214550B (sh)
YU (1) YU47694B (sh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9309574B1 (en) 1984-08-22 2016-04-12 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Molecular cloning of HIV-1 from immortalized cell lines
FR2681865B1 (fr) * 1991-10-01 1993-11-19 Bel Laboratoire Roger Nouveaux derives de la benzonaphtyridine-1,8 leur preparation et les compositions qui les contiennent.
FR2703681B1 (fr) * 1993-04-08 1995-05-12 Bellon Labor Sa Roger Procede de preparation de fluoro-6-halogeno-2 quinoleine
US5883098A (en) * 1993-11-29 1999-03-16 Fujisawa Pharmaceutical Co., Ltd. Piperazine derivatives
DK1140932T3 (da) * 1998-12-21 2004-07-05 Aventis Pharma Sa Derivater af benzo-1,8-naphtyridin
FR2787452B1 (fr) * 1998-12-21 2004-10-22 Aventis Pharma Sa Nouveaux derives de la benzonaphtyridine-1,8, leur preparation et les compositions pharmaceutiques qui les contiennent
ES2200899T3 (es) 1999-06-30 2004-03-16 Aventis Pharma S.A. Nuevos derivados de benzo (f)naftiridina, su preparacion y las composiciones que los contienen.
FR2795729B1 (fr) * 1999-06-30 2001-08-10 Aventis Pharma Sa Nouveaux derives de la benzo[f]naphtyridine, leur preparation et les compositions les contenant
KR101599524B1 (ko) * 2015-07-31 2016-03-03 (주)기억되는 사람들 유골함

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133885A (en) * 1977-07-18 1979-01-09 Merck & Co., Inc. Substituted naphthyridinones
DE3420798A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
EP0230053A3 (en) * 1986-01-17 1988-03-30 American Cyanamid Company 7-(substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
NZ232091A (en) * 1989-01-16 1990-12-21 Bellon Labor Sa Roger 7-fluoro-8-(piperazin-1-yl)-4-oxo-1,4-dihydro-benzo(b)(1,8)naphthyridine-3-carboxylic acid derivatives, preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
BG60915B1 (bg) 1996-06-28
DK0431991T3 (da) 1994-02-28
EP0431991A1 (fr) 1991-06-12
IL96159A0 (en) 1991-07-18
PT95743A (pt) 1991-09-13
ATE100103T1 (de) 1994-01-15
NO175433B (no) 1994-07-04
CA2028730A1 (fr) 1991-05-01
RO108347B1 (ro) 1994-04-28
FI905329A0 (fi) 1990-10-29
NO904683L (no) 1991-05-02
HU208138B (en) 1993-08-30
IE903897A1 (en) 1991-05-08
CZ529790A3 (en) 1995-11-15
FI92068C (fi) 1994-09-26
CZ280513B6 (cs) 1996-02-14
TW214550B (sh) 1993-10-11
PL164270B1 (pl) 1994-07-29
NZ235890A (en) 1992-04-28
DE69005994D1 (de) 1994-02-24
RU2047613C1 (ru) 1995-11-10
DE69005994T2 (de) 1994-05-11
JPH03151384A (ja) 1991-06-27
HUT55778A (en) 1991-06-28
YU205390A (sh) 1992-09-07
FI92068B (fi) 1994-06-15
AU629997B2 (en) 1992-10-15
US5053509A (en) 1991-10-01
KR910007928A (ko) 1991-05-30
NO175433C (no) 1994-10-12
PT95743B (pt) 1997-09-30
IL96159A (en) 1994-12-29
NO904683D0 (no) 1990-10-29
EP0431991B1 (fr) 1994-01-12
PL287563A1 (en) 1991-07-01
IE65099B1 (en) 1995-10-04
ES2062455T3 (es) 1994-12-16
AU6555190A (en) 1991-05-02
HU906926D0 (en) 1991-05-28

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