YU45827B - Novi 6-ili 7-metilenandrosta-1-4-dien-3,17-dionski derivati i postupak za njihovo dobijanje - Google Patents

Novi 6-ili 7-metilenandrosta-1-4-dien-3,17-dionski derivati i postupak za njihovo dobijanje

Info

Publication number
YU45827B
YU45827B YU129487A YU129487A YU45827B YU 45827 B YU45827 B YU 45827B YU 129487 A YU129487 A YU 129487A YU 129487 A YU129487 A YU 129487A YU 45827 B YU45827 B YU 45827B
Authority
YU
Yugoslavia
Prior art keywords
methylenandrosta
new
hydrogen
dien
obtaining
Prior art date
Application number
YU129487A
Other languages
English (en)
Other versions
YU129487A (en
Inventor
F. Buzzetti
N. Barbugian
P. Lombardi
E. Di Salle
Original Assignee
Farmitalia Carlo Erba S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba S.P.A. filed Critical Farmitalia Carlo Erba S.P.A.
Publication of YU129487A publication Critical patent/YU129487A/xx
Publication of YU45827B publication Critical patent/YU45827B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NOVI 6-ILI 7-METILENANDROSTA-1-4-DIEN-3,17-DIONSKI DERIVATI I POSTUPAK ZA NJIHOVO DOBIJANJE, Postupak za dobijanje jedinjenja formule (I): naznačen time, što obuhvata: dehidrogenizaciju jedinjenja formule (III): u kojoj su (X) i (Y) R, R1, R3 i R4 prethodno definisani, sa sredstvom za dehidrogenizaciju koje je izabrano iz grupe koja obuhvata dihlorodicijanobenzohinon, selendioksid, hloranil anhidrid i anhidrid benzolselenove kiseline, u organskom rastvaraču kao što je dioksan, benzol, toluol, ili dihlormetan, na temperaturi od oko 40 C do oko 100C. Prijava sadrži još 1 nezavisan zahtev.
YU129487A 1986-07-14 1987-07-10 Novi 6-ili 7-metilenandrosta-1-4-dien-3,17-dionski derivati i postupak za njihovo dobijanje YU45827B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868617107A GB8617107D0 (en) 1986-07-14 1986-07-14 6-/7-methylenandrosta-1 4-diene-3 17-dione derivatives

Publications (2)

Publication Number Publication Date
YU129487A YU129487A (en) 1988-10-31
YU45827B true YU45827B (sh) 1992-07-20

Family

ID=10601019

Family Applications (1)

Application Number Title Priority Date Filing Date
YU129487A YU45827B (sh) 1986-07-14 1987-07-10 Novi 6-ili 7-metilenandrosta-1-4-dien-3,17-dionski derivati i postupak za njihovo dobijanje

Country Status (24)

Country Link
US (1) US4824830A (sh)
EP (1) EP0253591B1 (sh)
JP (1) JP2643943B2 (sh)
CN (1) CN87104750A (sh)
AT (1) ATE44282T1 (sh)
AU (1) AU589269B2 (sh)
CA (1) CA1309400C (sh)
CS (1) CS262695B2 (sh)
DE (1) DE3760277D1 (sh)
DK (1) DK364787A (sh)
ES (1) ES2010513B3 (sh)
FI (1) FI873052A (sh)
GB (1) GB8617107D0 (sh)
GR (1) GR3000085T3 (sh)
HU (1) HU196223B (sh)
IL (1) IL83132A (sh)
MY (1) MY100512A (sh)
NO (1) NO872892D0 (sh)
NZ (1) NZ221012A (sh)
PH (1) PH22994A (sh)
PT (1) PT85318B (sh)
SU (1) SU1549485A3 (sh)
YU (1) YU45827B (sh)
ZA (1) ZA875098B (sh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5719448A (en) * 1989-03-07 1998-02-17 Seiko Epson Corporation Bonding pad structures for semiconductor integrated circuits
US5227375A (en) * 1990-02-08 1993-07-13 Endorecherche, Inc. Aromatase inhibitors
JP2602456B2 (ja) * 1990-04-12 1997-04-23 雪印乳業株式会社 子宮内膜症治療剤
CH683151A5 (de) * 1991-04-24 1994-01-31 Ciba Geigy Ag Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
GB9217035D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Androst-4-eno(4,5-b)pyrrole derivatives and process for their preparation
NZ261123A (en) * 1993-02-18 1996-08-27 Erba Carlo Spa Fluorinated 4-aminoandrostadienone derivatives
GB9313420D0 (en) * 1993-06-29 1993-08-11 Erba Carlo Spa Fluorinated 6-methylenandrosta-1,4-dien-3-one-derivatives and process for their preparations
FI109641B (fi) * 2000-03-10 2002-09-13 Nokia Corp Mikrofonirakenne
DK1377298T3 (da) * 2001-01-26 2007-01-02 Pfizer Italia Srl Exemestan til behandling af hormon-afhængige lidelser
US20040082557A1 (en) * 2001-01-26 2004-04-29 Wajszczuk Charles Paul Methods for treating estrogen-dependent disorders
US20050101581A1 (en) * 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
US8183401B2 (en) * 2004-01-16 2012-05-22 Cedarburg Pharmaceuticals, Inc. Exemestane and its intermediates and methods of making the same
US20080275259A1 (en) * 2007-05-04 2008-11-06 Scinopharm Taiwan, Ltd Process for preparing aromatase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB929985A (sh) *
US2744120A (en) * 1953-01-14 1956-05-01 Olin Mathieson 1-dehydrotestololactone
US4235893A (en) * 1978-05-08 1980-11-25 Brodie Angela M Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
DE3322285A1 (de) * 1983-06-18 1984-12-20 Schering AG, 1000 Berlin und 4709 Bergkamen 1-alkyl-androsta-1,4-dien-3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
DE3485093D1 (de) * 1984-12-28 1991-10-24 Ibm Zuechtungsverfahren und vorrichtung zur herstellung von siliciumkristallen mit hohem und kontrolliertem kohlenstoffgehalt.
GB8517360D0 (en) * 1985-07-09 1985-08-14 Erba Farmitalia Substituted androsta-1,4-diene-3,17-diones
JPH0718729B2 (ja) * 1990-06-11 1995-03-06 山武ハネウエル株式会社 ヒータ温度制御回路

Also Published As

Publication number Publication date
GB8617107D0 (en) 1986-08-20
FI873052A0 (fi) 1987-07-10
SU1549485A3 (ru) 1990-03-07
DK364787A (da) 1988-01-15
PT85318B (pt) 1990-04-30
DK364787D0 (da) 1987-07-13
PH22994A (en) 1989-02-24
ES2010513B3 (es) 1989-11-16
IL83132A (en) 1992-01-15
ZA875098B (en) 1988-03-30
FI873052A (fi) 1988-01-15
AU589269B2 (en) 1989-10-05
CA1309400C (en) 1992-10-27
PT85318A (en) 1987-08-01
JPS6323895A (ja) 1988-02-01
HUT44038A (en) 1988-01-28
IL83132A0 (en) 1987-12-31
DE3760277D1 (en) 1989-08-03
YU129487A (en) 1988-10-31
US4824830A (en) 1989-04-25
AU7550887A (en) 1988-01-21
GR3000085T3 (en) 1990-10-31
NO872892D0 (no) 1987-07-10
ATE44282T1 (de) 1989-07-15
MY100512A (en) 1990-10-30
CN87104750A (zh) 1988-03-23
CS535087A2 (en) 1988-08-16
NZ221012A (en) 1989-05-29
EP0253591B1 (en) 1989-06-28
JP2643943B2 (ja) 1997-08-25
EP0253591A1 (en) 1988-01-20
HU196223B (en) 1988-10-28
CS262695B2 (en) 1989-03-14

Similar Documents

Publication Publication Date Title
YU45827B (sh) Novi 6-ili 7-metilenandrosta-1-4-dien-3,17-dionski derivati i postupak za njihovo dobijanje
ATE44748T1 (de) 4-substituierte 6-alkylidene-androsten-3,17-dion- derivate und verfahren zu ihrer herstellung.
FI890302A (fi) Parannus androsta-1,4-dieeni-3,17-dionin 6-metyleenijohdannaisten synteesissä
ATE79629T1 (de) 17-substituierte androsta-1,4-dien-3-on-derivate.
DE69023939T2 (de) Förderung der Osteogenese durch Verwendung von Vitamin D-Derivaten.
UA40567C2 (uk) Похідні фосфоліпідів, спосіб отримання похідних фосфоліпідів, фармацевтична композиція та спосіб її отримання
ATE40140T1 (de) Aromatase inhibierende steroide.