YU43290B - Process for preparing inclusioned complex of ibuproxane with beta-cyclodextrine - Google Patents

Process for preparing inclusioned complex of ibuproxane with beta-cyclodextrine

Info

Publication number
YU43290B
YU43290B YU1932/86A YU193286A YU43290B YU 43290 B YU43290 B YU 43290B YU 1932/86 A YU1932/86 A YU 1932/86A YU 193286 A YU193286 A YU 193286A YU 43290 B YU43290 B YU 43290B
Authority
YU
Yugoslavia
Prior art keywords
inclusioned
ibuproxane
cyclodextrine
beta
preparing
Prior art date
Application number
YU1932/86A
Other languages
English (en)
Other versions
YU193286A (en
Inventor
M Zorz
J Zmitek
J Milovac
Z Kopitar
B Rusjakovski
Original Assignee
Lek Tovarna Farmacevtskih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Tovarna Farmacevtskih filed Critical Lek Tovarna Farmacevtskih
Priority to YU1932/86A priority Critical patent/YU43290B/xx
Priority to DE87116738T priority patent/DE3787703D1/de
Priority to AU81173/87A priority patent/AU605517B2/en
Priority to EP87116738A priority patent/EP0268215B1/fr
Priority to JP62285683A priority patent/JPS63183546A/ja
Priority to US07/119,933 priority patent/US4952565A/en
Publication of YU193286A publication Critical patent/YU193286A/xx
Publication of YU43290B publication Critical patent/YU43290B/xx

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pain & Pain Management (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU1932/86A 1986-11-13 1986-11-13 Process for preparing inclusioned complex of ibuproxane with beta-cyclodextrine YU43290B (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
YU1932/86A YU43290B (en) 1986-11-13 1986-11-13 Process for preparing inclusioned complex of ibuproxane with beta-cyclodextrine
DE87116738T DE3787703D1 (de) 1986-11-13 1987-11-12 Inklusionskomplex von Ibuproxam mit beta-Cyclodextrin, Verfahren zur Herstellung und diesen Inklusionskomplex enthaltendes pharmazeutisches Präparat.
AU81173/87A AU605517B2 (en) 1986-11-13 1987-11-12 Inclusion complex of ibuproxam with beta-cyclodextrin, a process for preparing the same and a pharmaceutical preparation containing the same
EP87116738A EP0268215B1 (fr) 1986-11-13 1987-11-12 Complexe d'inclusion de bêta-cyclodextrine avec l'ibuproxame, procédé de préparation et composition pharmaceutique contenant ce complexe
JP62285683A JPS63183546A (ja) 1986-11-13 1987-11-13 イブプロキサムとβ‐シクロデキストリンとの包接複合体、その製造法及びそれを含有する医薬製剤
US07/119,933 US4952565A (en) 1986-11-13 1987-11-13 Inclusion complex of ibuproxam with beta-cyclodextrin, a process for preparing the same and a pharmaceutical preparation containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU1932/86A YU43290B (en) 1986-11-13 1986-11-13 Process for preparing inclusioned complex of ibuproxane with beta-cyclodextrine

Publications (2)

Publication Number Publication Date
YU193286A YU193286A (en) 1988-06-30
YU43290B true YU43290B (en) 1989-06-30

Family

ID=25556166

Family Applications (1)

Application Number Title Priority Date Filing Date
YU1932/86A YU43290B (en) 1986-11-13 1986-11-13 Process for preparing inclusioned complex of ibuproxane with beta-cyclodextrine

Country Status (6)

Country Link
US (1) US4952565A (fr)
EP (1) EP0268215B1 (fr)
JP (1) JPS63183546A (fr)
AU (1) AU605517B2 (fr)
DE (1) DE3787703D1 (fr)
YU (1) YU43290B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU45837B (sh) * 1988-01-18 1992-07-20 LEK TOVARNA FARMACEVTSKIH IN KEMIČKIH IZDELKOV d.d. Postopek za pripravo novega inkluzijskega kompleksa nikardipina oz. njegovega hidroklorida z beta-ciklodekstrinom
FR2660309B1 (fr) * 1990-03-27 1992-07-17 Roussel Uclaf Nouveaux complexes de l'acide tiaprofenique ou de ses esters insolubles ou partiellement solubles avec les cyclodextrines ou leurs derives.
US5024997A (en) * 1990-06-22 1991-06-18 American Home Products Corporation Palatable ibuprofen solutions
GB9207990D0 (en) * 1992-04-10 1992-05-27 Smithkline Beecham Plc Pharmaceutical composition
CN1088600C (zh) * 1993-07-31 2002-08-07 史密丝克莱恩比彻姆有限公司 布洛芬－β－环糊精配合物的用途
US5866162A (en) * 1993-08-10 1999-02-02 Smithkline Beecham P.L.C. Pharmaceutical composition containing a drug/β-cyclodextrin complex in combination with an acid-base couple
SI9300470A (en) * 1993-09-10 1995-04-30 Lek Tovarna Farmacevtskih Inclusion complexes of optically active and racemic ibuproxan with cyclodextrin derivates,process for their preparation,pharmaceutical preparations comprising the same and their use
AU2531295A (en) * 1994-05-27 1995-12-21 Farmarc Nederland Bv Pharmaceutical composition
EP0935669B1 (fr) 1996-05-20 2002-07-31 Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. Synthese enzymatique d'acides hydroxamiques optiquement actifs et leur conversion en amines primaires optiquement actives par transposition de lossen
US5942501A (en) * 1996-08-16 1999-08-24 Collaborative Laboratories, Inc. Cyclodextrin derivative complex
US6884885B2 (en) * 2000-12-21 2005-04-26 Cerestar Holding B.V. Production of cyclodextrin complexes
KR100473716B1 (ko) * 2002-03-27 2005-03-08 주식회사 참 존 7-디하이드로콜레스테롤 및 사이클로덱스트린의 포접복합체, 이를 포함하는 화장료 조성물 및7-디하이드로콜레스테롤의 안정화방법
JP4847711B2 (ja) * 2004-04-16 2011-12-28 株式会社日立ハイテクノロジーズ 荷電粒子線装置
KR20160033796A (ko) * 2006-03-28 2016-03-28 자블린 파머슈티칼스 인코포레이티드 저 복용량의 디클로페낙 및 베타-사이클로덱스트린 제형
ITRM20070038A1 (it) * 2007-01-26 2008-07-27 Uni Degli Studi Di Roma La Sapienza Forme solubili di complessi di inclusione di inibitori dell istone deacetilasi e ciclodestrine loro processi di preparazione e impieghi in campo farmaceutico

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082707A (en) * 1973-01-08 1978-04-04 Societa Italo-Britannica L. Manetti-H. Roberts & Co. 2-(4-isobutylphenyl)-propiohydroxamic acid and a procedure for its preparation
GB1447658A (en) * 1973-01-08 1976-08-25 Manetti & Roberts Italo Brit 2- 4- isobutylphenyl- propionic acid derivative
US4061668A (en) * 1974-12-06 1977-12-06 Societa Italo-Britannica L. Manetti - H. Roberts & C. Process for the preparation of 2-(4-isobutylphenyl)-propiohydroxamic acid
HU176215B (en) * 1978-01-27 1981-01-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1
JPS5592341A (en) * 1979-01-05 1980-07-12 Kaken Pharmaceut Co Ltd Preparation of clathrate compound
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition

Also Published As

Publication number Publication date
AU605517B2 (en) 1991-01-17
AU8117387A (en) 1988-05-19
YU193286A (en) 1988-06-30
JPS63183546A (ja) 1988-07-28
DE3787703D1 (de) 1993-11-11
US4952565A (en) 1990-08-28
EP0268215A1 (fr) 1988-05-25
EP0268215B1 (fr) 1993-10-06

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