YU42587B - Process for producing aza-bicyclo-octane-carboxylic acids - Google Patents

Process for producing aza-bicyclo-octane-carboxylic acids

Info

Publication number
YU42587B
YU42587B YU2454/81A YU245481A YU42587B YU 42587 B YU42587 B YU 42587B YU 2454/81 A YU2454/81 A YU 2454/81A YU 245481 A YU245481 A YU 245481A YU 42587 B YU42587 B YU 42587B
Authority
YU
Yugoslavia
Prior art keywords
aza
bicyclo
octane
producing
carboxylic acids
Prior art date
Application number
YU2454/81A
Other languages
English (en)
Other versions
YU245481A (en
Inventor
M Vincent
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of YU245481A publication Critical patent/YU245481A/xx
Publication of YU42587B publication Critical patent/YU42587B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
YU2454/81A 1980-10-21 1981-10-13 Process for producing aza-bicyclo-octane-carboxylic acids YU42587B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8022438A FR2492381A1 (fr) 1980-10-21 1980-10-21 Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme

Publications (2)

Publication Number Publication Date
YU245481A YU245481A (en) 1984-04-30
YU42587B true YU42587B (en) 1988-10-31

Family

ID=9247120

Family Applications (1)

Application Number Title Priority Date Filing Date
YU2454/81A YU42587B (en) 1980-10-21 1981-10-13 Process for producing aza-bicyclo-octane-carboxylic acids

Country Status (29)

Country Link
US (1) US4397857A (cs)
EP (1) EP0051020B1 (cs)
JP (2) JPS5798281A (cs)
KR (1) KR860001877B1 (cs)
AR (1) AR228621A1 (cs)
AT (1) ATE8892T1 (cs)
AU (1) AU540609B2 (cs)
CA (1) CA1183140A (cs)
DD (1) DD201891A5 (cs)
DE (1) DE3165428D1 (cs)
DK (1) DK162444C (cs)
EG (1) EG15419A (cs)
ES (1) ES506222A0 (cs)
FI (1) FI73678C (cs)
FR (2) FR2492381A1 (cs)
GR (1) GR75389B (cs)
HU (1) HU185058B (cs)
IE (1) IE51823B1 (cs)
IL (1) IL64075A0 (cs)
MA (1) MA19307A1 (cs)
MX (1) MX155032A (cs)
NO (1) NO155098C (cs)
NZ (1) NZ198701A (cs)
OA (1) OA06930A (cs)
PH (1) PH17338A (cs)
PT (1) PT73857B (cs)
SU (1) SU1138022A3 (cs)
YU (1) YU42587B (cs)
ZA (1) ZA817251B (cs)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0050800B2 (en) * 1980-10-23 1995-06-07 Schering Corporation Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
IE54551B1 (en) * 1982-01-22 1989-11-22 Ici Plc Amide derivatives
DE3227055A1 (de) * 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung
DE3246757A1 (de) * 1982-12-17 1984-06-20 Hoechst Ag, 6230 Frankfurt Neue 2-azabicyclo(2.2.1)heptan-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(2.2.1)heptan-derivate als zwischenprodukte und verfahren zu deren herstellung
DE3303344A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
US4693996A (en) * 1985-12-23 1987-09-15 Warner-Lambert Company Method of treating heart failure and medicaments therefor
DE3707911C1 (de) * 1987-03-12 1988-03-31 Texaco Ag Bicyclische Aminkatalysatoren
FR2619813B1 (fr) * 1987-08-28 1991-05-03 Adir Nouveaux derives de l'acide aza - 2 bicyclooctane carboxylique - 3, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2635684A1 (fr) * 1988-08-24 1990-03-02 Adir Utilisation de derives de l'acide aza - 2 bicyclooctane (2.2.2) carboxylique - 3 pour l'obtention de medicaments destines au traitement des maladies consecutives a l'alteration de la paroi vasculaire ainsi qu'aux troubles de la microcirculation
JPH0426348U (cs) * 1990-06-25 1992-03-02
TW197945B (cs) * 1990-11-27 1993-01-11 Hoechst Ag
LT3872B (en) 1993-12-06 1996-04-25 Hoechst Ag Novel peptides and pharmaceutical compositions containing them
FR2746394B1 (fr) 1996-03-20 1998-05-29 Roussel Uclaf Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
EP0796855B1 (de) 1996-03-20 2002-02-06 Hoechst Aktiengesellschaft Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten
DE19653647A1 (de) 1996-12-20 1998-06-25 Hoechst Ag Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
CZ20024214A3 (cs) 2000-06-28 2003-04-16 Bristol-Myers Squibb Company Selektivní androgen receptorový modulátor, způsob jeho identifikace, jeho konstrukce a použití
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US7001911B2 (en) 2000-06-28 2006-02-21 Bristol-Myers Squibb Company Fused cyclic modulators of nuclear hormone receptor function
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
PL206962B1 (pl) * 2001-12-19 2010-10-29 Bristol Myers Squibb Co Związek heterocykliczny o budowie skondensowanej

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE94175C (cs) *
GB1095105A (en) * 1965-04-12 1967-12-13 Scherico Ltd Novel n-(phenyl-sulfonyl)-isoquinuclidine-carboxamides
US3741973A (en) * 1967-09-11 1973-06-26 Upjohn Co Oxygenated 3-azabicyclo(3.3.1)nonanes
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids

Also Published As

Publication number Publication date
PT73857B (fr) 1983-01-25
DK460181A (da) 1982-04-22
FR2525604A2 (fr) 1983-10-28
PT73857A (fr) 1981-11-01
AU7662481A (en) 1982-04-29
EP0051020B1 (fr) 1984-08-08
HU185058B (en) 1984-11-28
JPS61126025A (ja) 1986-06-13
PH17338A (en) 1984-08-01
IE51823B1 (en) 1987-04-01
DD201891A5 (de) 1983-08-17
FR2492381B1 (cs) 1983-08-12
ZA817251B (en) 1982-09-29
US4397857A (en) 1983-08-09
KR830007570A (ko) 1983-10-21
NO155098C (no) 1987-02-11
FR2492381A1 (fr) 1982-04-23
GR75389B (cs) 1984-07-13
JPS6146453B2 (cs) 1986-10-14
JPS5798281A (en) 1982-06-18
IE812460L (en) 1982-04-21
DE3165428D1 (en) 1984-09-13
IL64075A0 (en) 1982-01-31
FI813279L (fi) 1982-04-22
ES8301927A1 (es) 1983-01-01
MX155032A (es) 1988-01-21
OA06930A (fr) 1983-05-31
FI73678B (fi) 1987-07-31
DK162444B (da) 1991-10-28
ATE8892T1 (de) 1984-08-15
KR860001877B1 (ko) 1986-10-24
NO155098B (no) 1986-11-03
YU245481A (en) 1984-04-30
JPS6112911B2 (cs) 1986-04-10
DK162444C (da) 1992-03-23
FR2525604B2 (fr) 1985-06-07
CA1183140A (fr) 1985-02-26
EG15419A (en) 1986-03-31
NO813541L (no) 1982-04-22
EP0051020A1 (fr) 1982-05-05
AU540609B2 (en) 1984-11-29
ES506222A0 (es) 1983-01-01
FI73678C (fi) 1987-11-09
NZ198701A (en) 1984-07-06
SU1138022A3 (ru) 1985-01-30
AR228621A1 (es) 1983-03-30
MA19307A1 (fr) 1982-07-01

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