YU40334B - Process for obtaining isoxazolyl-carbamide derivatives - Google Patents

Process for obtaining isoxazolyl-carbamide derivatives

Info

Publication number
YU40334B
YU40334B YU1037/78A YU103778A YU40334B YU 40334 B YU40334 B YU 40334B YU 1037/78 A YU1037/78 A YU 1037/78A YU 103778 A YU103778 A YU 103778A YU 40334 B YU40334 B YU 40334B
Authority
YU
Yugoslavia
Prior art keywords
isoxazolyl
obtaining
carbamide derivatives
carbamide
derivatives
Prior art date
Application number
YU1037/78A
Other languages
English (en)
Other versions
YU103778A (en
Inventor
Y Makisumi
T Sasatani
A Murabayashi
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of YU103778A publication Critical patent/YU103778A/xx
Publication of YU40334B publication Critical patent/YU40334B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/48Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
YU1037/78A 1977-04-28 1978-04-28 Process for obtaining isoxazolyl-carbamide derivatives YU40334B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52049629A JPS6033109B2 (ja) 1977-04-28 1977-04-28 尿素誘導体の合成法

Publications (2)

Publication Number Publication Date
YU103778A YU103778A (en) 1982-10-31
YU40334B true YU40334B (en) 1985-12-31

Family

ID=12836505

Family Applications (1)

Application Number Title Priority Date Filing Date
YU1037/78A YU40334B (en) 1977-04-28 1978-04-28 Process for obtaining isoxazolyl-carbamide derivatives

Country Status (25)

Country Link
US (1) US4183856A (fr)
JP (1) JPS6033109B2 (fr)
AR (1) AR225666A1 (fr)
AU (1) AU513688B2 (fr)
BE (1) BE866581A (fr)
BG (1) BG33278A3 (fr)
BR (1) BR7802618A (fr)
CA (1) CA1093081A (fr)
CH (1) CH633542A5 (fr)
CS (1) CS198297B2 (fr)
DD (1) DD135905A5 (fr)
DE (1) DE2818947A1 (fr)
DK (1) DK144011C (fr)
ES (1) ES468897A1 (fr)
FR (1) FR2388802A1 (fr)
GB (1) GB1572976A (fr)
HU (1) HU176881B (fr)
IE (1) IE46769B1 (fr)
IL (1) IL54468A0 (fr)
IT (1) IT1111465B (fr)
NL (1) NL183513C (fr)
PL (1) PL110681B1 (fr)
SE (1) SE442867B (fr)
SU (1) SU1091853A3 (fr)
YU (1) YU40334B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8422461D0 (en) * 1984-09-05 1984-10-10 Wyeth John & Brother Ltd Pyridine derivatives
US4808722A (en) * 1985-10-31 1989-02-28 Fmc Corporation Pyridinylurea N-oxide compounds and agricultural uses
DE59005183D1 (de) * 1989-11-10 1994-05-05 Agrolinz Agrarchemikalien Verfahren zur Herstellung reiner, unsymmetrisch disubstituierter Harnstoffe.
DE3940261A1 (de) * 1989-12-06 1991-06-13 Agrolinz Agrarchemikalien Muen Verfahren zur herstellung reiner, unsymmetrisch disubstituierter harnstoffe
AU2002351748B2 (en) * 2001-12-21 2009-07-09 Novo Nordisk A/S Amide derivatives as GK activators
KR101116627B1 (ko) * 2002-06-27 2012-10-09 노보 노르디스크 에이/에스 치료제로서 아릴 카르보닐 유도체
JP4834840B2 (ja) 2004-01-06 2011-12-14 ノヴォ ノルディスク アー/エス ヘテロアリール尿素およびグルコキナーゼ活性化剤としてのその使用
EP1904466A1 (fr) * 2005-07-08 2008-04-02 Novo Nordisk A/S Activateurs de dicycloalkylurée glucokinase
WO2007006761A1 (fr) * 2005-07-08 2007-01-18 Novo Nordisk A/S Dicycloalkylcarbamoylurées en tant qu’activateurs de glucokinase
CN101263131B (zh) * 2005-07-14 2013-04-24 特兰斯特克药品公司 脲葡糖激酶活化剂
JP2010515701A (ja) * 2007-01-09 2010-05-13 ノボ・ノルデイスク・エー/エス ウレアグルコキナーゼアクチベーター
EP2099777B1 (fr) * 2007-01-11 2015-08-12 Novo Nordisk A/S Activateurs de l'urée glucokinase
JP2021526130A (ja) 2018-06-12 2021-09-30 ブイティーブイ・セラピューティクス・エルエルシー インスリンまたはインスリン類似体と組み合わせたグルコキナーゼ活性化薬の治療的使用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2755285A (en) * 1956-07-17 I-xsubstituted
US2756135A (en) * 1955-07-13 1956-07-24 Du Pont 1-methyl-3-(2-benzothiazolyl)-ureas and their use as herbicides
DE1209801B (de) * 1963-05-11 1966-01-27 Bayer Ag Unkrautbekaempfung in Rueben
US3293257A (en) * 1964-09-14 1966-12-20 United States Borax Chem Pyridyl urea compounds
FR1533184A (fr) * 1965-04-06 1968-07-19 Pechiney Saint Gobain Dérivés du thiazole
DE1620448C3 (de) * 1965-05-08 1974-08-29 Schering Ag, 1000 Berlin Und 4619 Bergkamen Harnstoff- bzw. Thioharnstoffderivate des 3-Methylisothiazols
US3622593A (en) * 1967-08-09 1971-11-23 Fmc Corp 1,1-dimethyl-3-(isothiazol-5-yl)urea
US3547940A (en) * 1967-10-31 1970-12-15 Du Pont Substituted ureido isoxazoles
GB1266769A (fr) * 1969-08-15 1972-03-15
US4062861A (en) * 1973-07-27 1977-12-13 Shionogi & Co., Ltd. 3-Isoxazolylurea derivatives
JPS5031039A (fr) * 1973-07-27 1975-03-27
US4013706A (en) * 1973-11-14 1977-03-22 Sucreries Du Soissonnais Et Compagnie Sucriere Derivatives of substituted urea, acyl ureas, and sulphonyl ureas, and a process for producing the same
US4046770A (en) * 1974-08-30 1977-09-06 Eli Lilly And Company N-(6-acyloxybenzothiazol-2-yl)-N'-phenyl (or substituted phenyl)ureas
JPS5810361B2 (ja) * 1974-10-04 1983-02-25 塩野義製薬株式会社 3−アルチルイソオキサゾ−ル系除草剤

Also Published As

Publication number Publication date
JPS6033109B2 (ja) 1985-08-01
JPS53135972A (en) 1978-11-28
CS198297B2 (en) 1980-05-30
YU103778A (en) 1982-10-31
CH633542A5 (de) 1982-12-15
GB1572976A (en) 1980-08-13
DK144011C (da) 1982-04-26
BR7802618A (pt) 1979-04-03
PL110681B1 (en) 1980-07-31
AR225666A1 (es) 1982-04-15
NL7804550A (nl) 1978-10-31
US4183856A (en) 1980-01-15
PL206450A1 (pl) 1979-03-26
IE46769B1 (en) 1983-09-21
AU513688B2 (en) 1980-12-18
IE780707L (en) 1978-10-28
SU1091853A3 (ru) 1984-05-07
FR2388802A1 (fr) 1978-11-24
FR2388802B1 (fr) 1980-04-04
DE2818947A1 (de) 1978-11-02
SE442867B (sv) 1986-02-03
DD135905A5 (de) 1979-06-06
DE2818947C2 (fr) 1991-08-22
IT7867959A0 (it) 1978-04-27
NL183513C (nl) 1988-11-16
ES468897A1 (es) 1978-11-16
IT1111465B (it) 1986-01-13
AU3546878A (en) 1979-11-01
DK144011B (da) 1981-11-16
HU176881B (en) 1981-05-28
DK180378A (da) 1978-10-29
NL183513B (nl) 1988-06-16
CA1093081A (fr) 1981-01-06
BE866581A (fr) 1978-08-14
IL54468A0 (en) 1978-07-31
BG33278A3 (en) 1983-01-14
SE7804596L (sv) 1978-10-29

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