YU39291B - Process for obtaining cefalexin monohydrate - Google Patents

Process for obtaining cefalexin monohydrate

Info

Publication number
YU39291B
YU39291B YU994/70A YU99470A YU39291B YU 39291 B YU39291 B YU 39291B YU 994/70 A YU994/70 A YU 994/70A YU 99470 A YU99470 A YU 99470A YU 39291 B YU39291 B YU 39291B
Authority
YU
Yugoslavia
Prior art keywords
obtaining
cefalexin monohydrate
cefalexin
monohydrate
obtaining cefalexin
Prior art date
Application number
YU994/70A
Other languages
English (en)
Other versions
YU99470A (en
Inventor
R R Pfeiffer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of YU99470A publication Critical patent/YU99470A/xx
Publication of YU39291B publication Critical patent/YU39291B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Food-Manufacturing Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
YU994/70A 1969-04-21 1970-04-16 Process for obtaining cefalexin monohydrate YU39291B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81812569A 1969-04-21 1969-04-21

Publications (2)

Publication Number Publication Date
YU99470A YU99470A (en) 1982-02-28
YU39291B true YU39291B (en) 1984-10-31

Family

ID=25224730

Family Applications (1)

Application Number Title Priority Date Filing Date
YU994/70A YU39291B (en) 1969-04-21 1970-04-16 Process for obtaining cefalexin monohydrate

Country Status (13)

Country Link
US (1) US3531481A (da)
JP (1) JPS505255B1 (da)
AT (1) AT296504B (da)
BR (1) BR6914945D0 (da)
CH (1) CH529790A (da)
CS (1) CS162720B2 (da)
DK (1) DK129458B (da)
ES (1) ES378832A1 (da)
GT (1) GT197016708A (da)
NO (1) NO135068C (da)
PL (1) PL80590B1 (da)
SE (1) SE361318B (da)
YU (1) YU39291B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1317159A (en) * 1969-09-26 1973-05-16 Glaxo Lab Ltd Manufacture of cephalosporin compounds
US3687948A (en) * 1970-11-23 1972-08-29 Bristol Myers Co 7-{8 D-(a-AMINO-a-PHENYLACETAMIDO){9 -3-(4-METHYL-1,3-OXAZOL-2-YLTHIOMETHYL-3-CEPHEM-4-CARBOXYLIC ACID AND SALTS THEREOF
US3692781A (en) * 1971-02-26 1972-09-19 Glaxo Lab Ltd Recovery of pure cephalexin from acidic reaction mixtures
DE2317179C2 (de) * 1973-04-05 1982-11-25 Bristol-Myers Co., 10154 New York, N.Y. Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat
JPS5621395B2 (da) * 1973-07-18 1981-05-19
US4033956A (en) * 1975-07-22 1977-07-05 Richardson-Merrell Inc. 7[α-Amino-ω-(2,3-methylenedioxy-phenyl)acylamido]cephalosporanic acid derivatives
US4020060A (en) * 1975-07-22 1977-04-26 Richardson-Merrell Inc. 7-[α-Amino-ω-(3,4-methylenedioxyphenyl)acylamido]cephalosporanic acid derivatives
JPS5474966U (da) * 1977-11-07 1979-05-28
IT1126544B (it) * 1979-12-07 1986-05-21 Dobfar Spa Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
JPS6293589U (da) * 1985-11-29 1987-06-15
US5374719A (en) * 1993-06-04 1994-12-20 Eli Lilly And Company Process for converting loracarbef dihydrate to loracarbef monohydrate
US5352782A (en) * 1993-06-04 1994-10-04 Eli Lilly And Company Process for preparing crystalline β-lactam monohydrate
US5399686A (en) * 1993-06-04 1995-03-21 Eli Lilly And Company Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
US5412094A (en) * 1993-06-28 1995-05-02 Eli Lilly And Company Bicyclic beta-lactam/paraben complexes
US5580977A (en) * 1995-03-01 1996-12-03 Eli Lilly And Company Process for preparing loracarbef monohydrate
US6001996A (en) * 1995-05-11 1999-12-14 Eli Lilly And Company Complexes of cephalosporins and carbacephalosporins with parabens
AT406774B (de) * 1997-02-19 2000-08-25 Takeda Chemical Industries Ltd Cephalosporinkristalle und deren herstellung
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
CN113845529B (zh) * 2021-10-15 2024-02-27 东南大学 一种头孢氨苄共晶化合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3382241A (en) * 1967-02-27 1968-05-07 Lilly Co Eli Certain orally active cephalosporin antibiotics

Also Published As

Publication number Publication date
CS162720B2 (da) 1975-07-15
NO135068B (da) 1976-10-25
JPS505255B1 (da) 1975-03-01
NO135068C (da) 1977-02-02
AT296504B (de) 1972-02-25
PL80590B1 (en) 1975-08-30
CH529790A (de) 1972-10-31
BR6914945D0 (pt) 1973-04-19
DK129458C (da) 1975-04-21
DK129458B (da) 1974-10-14
YU99470A (en) 1982-02-28
ES378832A1 (es) 1972-07-16
US3531481A (en) 1970-09-29
SE361318B (da) 1973-10-29
GT197016708A (es) 1971-10-12

Similar Documents

Publication Publication Date Title
YU39291B (en) Process for obtaining cefalexin monohydrate
YU36509B (en) Process for obtaining aryl substituted piperazinylalkylamino-uraci, - uracilethers and - uracilthioethers
YU238570A (en) Process for obtaining amino-alshols
YU36389B (en) Process for obtaining antibiotics
YU122071A (en) Process for obtaining 7-halolincomycins
IL35793A0 (en) Continuous process for crystallization
IL33920A0 (en) Process for the manufacture of oximino-dithiolanes
YU205470A (en) Process for obtaining cephalosporin compounds
ZA713005B (en) Purification process
YU33170A (en) Process for obtaining deacetoxy cephalosporin esters
YU36185B (en) Process for obtaining cephalosporin compounds
YU201378A (en) Process for obtaining 3-amino-delta2-pyrazoline
ZA716751B (en) Purification process
YU36183B (en) Process for obtaining 7-aminocephalosporinic acid
YU35116B (en) Process for obtaining novel dimethylaminopropylthiocarbamates
YU36157B (en) Process for obtaining substituted bis-carbamates
YU36371B (en) Process for obtaining substituted phenyl-carbamates
ZA706130B (en) Process for producing aluminum
KR780000173B1 (en) Process for producting -aryl-2aminoalkoxy-styrole
KR780000171B1 (en) Process for producting-aryl-2aminoalkoxy-styrole
ZA716077B (en) Purification process
IL35502A (en) Process for the manufacture of n-mercaptomethyl-phthalimide
YU279769A (en) Process for obtaining penicillins
YU166270A (en) Process for obtaining bis-alkanolamine derivatives
YU35107B (en) Process for obtaining l-delta-hydrazino-beta-phenylpropionic acid