YU192281A - Process for preparing 3-(n-arylamino)-tetrahydrothiophen-2-ones - Google Patents
Process for preparing 3-(n-arylamino)-tetrahydrothiophen-2-onesInfo
- Publication number
- YU192281A YU192281A YU01922/81A YU192281A YU192281A YU 192281 A YU192281 A YU 192281A YU 01922/81 A YU01922/81 A YU 01922/81A YU 192281 A YU192281 A YU 192281A YU 192281 A YU192281 A YU 192281A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- group
- substituents
- alkyl
- substituted
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1. A process for the preparation of a 3-(N-arylamino)-tetrahydrothiophen-2-one derivate of the general formula A see diagramm : EP0046138,P13,F1 in which the heterocyclic five-membered ring is unsubstituted or substituted by one or more C1 -C4 -alkyl groups, n is an integer from 0 to 5, R signifies a number, spezified by n, of substituents selected from the group consisting of C1 -C12 alkyl, C1 -C12 alkoxy, halogen, nitro and -CH2 -X-R", or in which two substituents R which are adjacent to each other, together with the phenyl group, form a naphthyl ring, X being oxygen or sulfur and R" being C1 -C12 alkyl, phenyl or benzyl, each of which is unsubstituted or substituted by one or more members selected from the group consisting of lower alkyl, lower alkoxy, halogen and nitro, and R' is hydrogen or the -CO-R"' group, in which R"' is an aliphatic, heterocyclicaliphatic or heterocyclic radical, each heterocyclic structure containing one or more N, O and/or S atoms, or in which R" is an aromatic radical or an araliphatic radical, each of which radicals may be halogenated in the aromatic moiety and an aliphatic chain in any one of the substituents R"' may be interrupted by one or more oxygen, sulfur or nitrogen atoms ; which process comprises reacting a compound of formula B see diagramm : EP0046138,P13,F2 in which the possible substituents are as defined for formula A, with a salt of a thiocarboxylic acid of formula III R-COS-X in which R is a substituted or unsubstituted aliphatic or aromatic radical and X is a cation from the first to fourth main groups or the first to eight subgroups of the Periodic Table, in an organic solvent and at a temperature in the range from about +15 to +200 degrees C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17682180A | 1980-08-08 | 1980-08-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU192281A true YU192281A (en) | 1983-06-30 |
Family
ID=22645980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU01922/81A YU192281A (en) | 1980-08-08 | 1981-08-06 | Process for preparing 3-(n-arylamino)-tetrahydrothiophen-2-ones |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0046138B1 (en) |
| JP (1) | JPS5754185A (en) |
| KR (1) | KR830006282A (en) |
| AT (1) | ATE16803T1 (en) |
| AU (1) | AU7388481A (en) |
| BR (1) | BR8105104A (en) |
| DK (1) | DK352081A (en) |
| ES (1) | ES8205409A1 (en) |
| GR (1) | GR82275B (en) |
| IL (1) | IL63513A (en) |
| PT (1) | PT73496B (en) |
| YU (1) | YU192281A (en) |
| ZA (1) | ZA815432B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR900100380A (en) * | 1989-05-20 | 1991-10-10 | Fisons Plc | Process for the preparation of anti-inflammatory aminophenol derivatives |
-
1981
- 1981-08-03 EP EP81810314A patent/EP0046138B1/en not_active Expired
- 1981-08-03 AT AT81810314T patent/ATE16803T1/en not_active IP Right Cessation
- 1981-08-06 IL IL63513A patent/IL63513A/en unknown
- 1981-08-06 YU YU01922/81A patent/YU192281A/en unknown
- 1981-08-06 GR GR65739A patent/GR82275B/el unknown
- 1981-08-07 ES ES504645A patent/ES8205409A1/en not_active Expired
- 1981-08-07 AU AU73884/81A patent/AU7388481A/en not_active Abandoned
- 1981-08-07 ZA ZA815432A patent/ZA815432B/en unknown
- 1981-08-07 BR BR8105104A patent/BR8105104A/en unknown
- 1981-08-07 PT PT73496A patent/PT73496B/en unknown
- 1981-08-07 DK DK352081A patent/DK352081A/en not_active Application Discontinuation
- 1981-08-08 KR KR1019810002889A patent/KR830006282A/en unknown
- 1981-08-08 JP JP56124640A patent/JPS5754185A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA815432B (en) | 1982-08-25 |
| EP0046138B1 (en) | 1985-12-04 |
| KR830006282A (en) | 1983-09-20 |
| ES504645A0 (en) | 1982-06-16 |
| AU7388481A (en) | 1982-02-11 |
| EP0046138A1 (en) | 1982-02-17 |
| IL63513A0 (en) | 1981-11-30 |
| IL63513A (en) | 1984-06-29 |
| BR8105104A (en) | 1982-04-27 |
| ATE16803T1 (en) | 1985-12-15 |
| PT73496A (en) | 1981-09-01 |
| JPS5754185A (en) | 1982-03-31 |
| ES8205409A1 (en) | 1982-06-16 |
| GR82275B (en) | 1984-12-13 |
| PT73496B (en) | 1983-07-06 |
| DK352081A (en) | 1982-02-09 |
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