Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
  • A61K8/35—Ketones, e.g. benzophenone
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
  • A61K8/37—Esters of carboxylic acids
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q3/00—Manicure or pedicure preparations
  • A61Q3/04—Nail coating removers

Definitions

• the present invention relates to a nail-coating remover that removes nail coatings such as nail enamel and gel nails, and more specifically to a gel-type nail coating remover.
• Nail enamel removers used to remove nail enamel applied to the surface of fingernails or toenails or to the surface of artificial nails are generally in liquid form.
• the remover is in liquid form, it is necessary to soak absorbent cotton in the remover and place it on the nail, and then wrap the finger in aluminum foil to prevent the organic solvents such as acetone from evaporating quickly. This causes the problem that not only the nail but also the skin is degreased, causing rough skin.
• gel-type removers containing thickeners are also known (for example, Patent Document 1).
• the remover is in the form of a gel, it does not drip when applied to the nail and can be applied only to the nail with pinpoint accuracy, which has the advantage of being easier to handle than liquid removers.
• the gel-type remover described in Patent Document 1 still requires the fingers to be wrapped in aluminum foil because the organic solvent, such as acetone, evaporates immediately after application, just like liquid removers. This causes the problem that the person being treated cannot use his or her fingers during the nail enamel removal process, and cannot perform other tasks.
• Patent Document 2 a remover that contains a specific thermoplastic resin and a specific organic solvent with a boiling point of 40 to 130°C.
• This remover has excellent film-forming properties, so the person being treated can move his or her fingers and perform other tasks during the nail enamel removal process.
• the problem that the present invention aims to solve is to provide a nail enamel remover that contains a specified amount of acetone or less, has excellent peelability of the nail enamel coating film, is easy to remove, and has excellent film-forming and application properties.
• the present invention relates to the following.
• the acetone content is 10% by mass or less, and Contains 10 to 30% by mass of polyvinylpyrrolidone (A)
• the solvent contains a combination of at least one oxygen-containing low-molecular-weight organic solvent (B1) selected from the group consisting of 1,3-dioxolane, ethyl acetate, and monoglyme and dimethyl carbonate (B2) in an amount of 50 to 85% by mass, A nail enamel remover, wherein the mass ratio (B1/B2) of the oxygen-containing low-molecular-weight organic solvent (B1) to the dimethyl carbonate (B2) is 10/90 to 50/50.
• ⁇ 2> The nail enamel remover according to the above ⁇ 1>, further comprising fumed silica.
• ⁇ 3> The nail enamel remover according to the above ⁇ 1>, further comprising ethanol.
• ⁇ 4> The nail enamel remover according to any one of the above ⁇ 1> to ⁇ 3>, wherein the mass ratio (B1/B2) of the oxygen-containing low-molecular-weight organic solvent (B1) to the dimethyl carbonate (B2) is 15/85 to 45/55.
• B1/B2> the mass ratio (B1/B2) of the oxygen-containing low-molecular-weight organic solvent (B1) to the dimethyl carbonate (B2) is 15/85 to 45/55.
• ⁇ 5> The nail enamel remover according to any one of ⁇ 1> to ⁇ 4> above, wherein the acetone content is substantially 0% by mass.
• ⁇ 6> The nail enamel remover according to any one of ⁇ 1> to ⁇ 5> above, which is in a gel form.
• the nail enamel remover of the present invention is substantially free of acetone, and therefore avoids damage to the skin and unpleasant odor caused by acetone, while exhibiting sufficient nail enamel peeling and removal properties.
• the nail enamel remover of the present invention has an acetone content limited to a predetermined amount or less, which makes it possible to avoid damage to the skin and unpleasant odors caused by acetone, and further has excellent peelability of the nail enamel coating film, good workability in removal, and excellent film-forming properties and application properties.
• the present embodiment is an example for explaining the present invention, and is not intended to limit the present invention to the following content.
• the present invention can be modified appropriately within the scope of its gist.
• the expression "XX-YY" means "XX or more and YY or less.”
• nail enamel remover refers to a remover that can remove nail enamel from both non-light-curing nail cosmetics, such as nail enamel, and light-curing nail cosmetics, such as soft gel nails.
• non-light-curing nail cosmetics such as nail enamel
• light-curing nail cosmetics such as soft gel nails.
• the main purpose is to remove the base coat.
• the nail enamel remover of the present invention contains 10% by mass or less of acetone, 10 to 30% by mass of polyvinylpyrrolidone (A), and 50 to 85% by mass of a combination of at least one oxygen-containing low molecular weight organic solvent (B1) selected from the group consisting of 1,3-dioxolane, ethyl acetate, and monoglyme and dimethyl carbonate (B2), with the mass ratio (B1/B2) of the oxygen-containing low molecular weight organic solvent (B1) to the dimethyl carbonate (B2) being 10/90 to 50/50.
• B1 oxygen-containing low molecular weight organic solvent
• thermoplastic resin polyvinylpyrrolidone (A) contained in the nail enamel remover of the present invention disperses in the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2) to form a three-dimensional network structure with a stable multilayer structure by interactions such as hydrogen bonds, resulting in a phenomenon of thickening.
• the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2) on the air side surface of the remover applied on the nail enamel evaporate, and the network structure of polyvinylpyrrolidone (A) forms a coating. The formation of the coating can suppress dripping of the remover.
• the formation of the coating suppresses the evaporation of the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2) from the air side surface of the remover, and the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2) penetrate into the nail enamel from the nail side surface of the remover, thereby efficiently removing the nail enamel. Furthermore, by suppressing volatilization on the air side surface and penetrating the nail enamel on the nail side surface, the inside of the remover also changes from a high-viscosity liquid state to a rubbery solid state, improving workability by reducing adhesion of the remover to the removal tool used when removing the remover.
• the acetone content of the nail enamel remover of the present invention is 10% by mass or less.
• the content of acetone is preferably 8% by mass or less, more preferably 6% by mass or less, even more preferably 4% by mass or less, even more preferably 2% by mass or less, and particularly preferably substantially 0% by mass (acetone-free).
• substantially 0% by mass means that it is below the detection limit of a general detection means.
• the nail enamel remover of the present invention contains polyvinylpyrrolidone (A) as a thermoplastic resin.
• polyvinylpyrrolidone (A) forms a coating as the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2) volatilize from the air side surface of the remover applied on the nail enamel, suppressing further evaporation of the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2) from the air side surface of the remover, and the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2) penetrate into the nail enamel from the nail side surface of the remover, thereby efficiently removing the nail enamel.
• dripping of the remover can be suppressed even if the finger is moved during the nail enamel removal operation, and the us
• polyvinylpyrrolidone commercially available products can be used, such as "Pitzcol (registered trademark)” manufactured by Daiichi Kogyo Seiyaku Co., Ltd., specifically, "K-90” (K value: 92 to 96, weight average molecular weight: 1,200,000), “K-50” (K value: 48 to 52, weight average molecular weight: 250,000), “K-30” (K value: 27 to 33, weight average molecular weight: 45,000), etc.
• K-90 K value: 92 to 96, weight average molecular weight: 1,200,000
• K-50 K value: 48 to 52, weight average molecular weight: 250,000
• K-30 K value: 27 to 33, weight average molecular weight: 45,000
• Ashland's products include "K-120 (K value: 114-130, weight average molecular weight: 2,100,000 to 3,000,000), "K-90” (K value: 85 to 90, weight average molecular weight: 1,000,000 to 1,700,000), “K-60” (K value: 50 to 62, weight average molecular weight: 390,000 to 470,000), and "K-30” (K value: 36 to 35, weight average molecular weight: 40,000 to 80,000).
• K90 K value: 84 to 95
• the K value is a viscosity characteristic value that correlates with molecular weight, and is calculated by applying the relative viscosity value (25° C.) measured by a capillary viscometer to the Fikentscher formula.
• the weight-average molecular weight of polyvinylpyrrolidone is preferably 40 to 120, more preferably 50 to 110, as the K value (a viscosity characteristic value that correlates with the molecular weight).
• K-50, K-60, K-90, etc. are preferred.
• the content of polyvinylpyrrolidone (A) in the nail enamel remover of the present invention is 10-30% by mass, and from the viewpoint of forming a coating, it is preferably 11% by mass or more, more preferably 12% by mass or more, and from the viewpoint of solubility in the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2), it is preferably 27% by mass or less, more preferably 25% by mass or less, and even more preferably 23% by mass or less.
• the content of polyvinylpyrrolidone (A) in the nail enamel remover of the present invention is preferably 11% by mass or more and 27% by mass or less, more preferably 12% by mass or more and 25% by mass or less, and even more preferably 12% by mass or more and 23% by mass or less.
• the oxygen-containing low molecular weight organic solvent (B1) contained in the nail enamel remover of the present invention is at least one selected from the group consisting of 1,3-dioxolane, ethyl acetate and monoglyme.
• the boiling point of ethyl acetate is 77°C, and that of monoglyme (1,2-dimethoxyethane) is 85°C.
• the content of the oxygen-containing low molecular weight organic solvent (B1) in the nail enamel remover of the present invention is preferably 5% by mass or more, more preferably 8% by mass or more, and even more preferably 10% by mass or more, from the viewpoint of the nail enamel removal performance, and is preferably 40% by mass or less, more preferably 35% by mass or less, and even more preferably 30% by mass or less, from the viewpoint of film formation and workability during nail enamel removal.
• the content of the oxygen-containing low molecular weight organic solvent (B1) in the nail enamel remover of the present invention is preferably 5% by mass or more and 40% by mass or less, more preferably 8% by mass or more and 35% by mass or less, and even more preferably 10% by mass or more and 30% by mass or less.
• the nail enamel remover of the present invention contains dimethyl carbonate (B2).
• the boiling point of dimethyl carbonate is 90°C.
• the content of dimethyl carbonate (B2) in the nail enamel remover of the present invention is preferably 30% by mass or more, more preferably 35% by mass or more, and even more preferably 40% by mass or more.
• the upper limit is preferably 70% by mass or less, more preferably 65% by mass or less, and even more preferably 60% by mass or less.
• the content of dimethyl carbonate (B2) in the nail enamel remover of the present invention is preferably 30% by mass or more and 70% by mass or less, more preferably 35% by mass or more and 65% by mass or less, and even more preferably 40% by mass or more and 60% by mass or less.
• the total content of the oxygen-containing low-molecular-weight organic solvent (B1) and dimethyl carbonate (B2) in the nail enamel remover of the present invention is 50 to 85 mass %, preferably 55 to 80 mass %, and more preferably 60 to 75 mass %.
• the mass ratio (B1/B2) of the oxygen-containing low-molecular-weight organic solvent (B1) to the dimethyl carbonate (B2) is 10/90 to 50/50, preferably 15/85 to 45/55, and more preferably 20/80 to 40/60.
• the film formation of the above-mentioned polyvinylpyrrolidone (A) the inhibitory effect of volatilization, the penetration effect into the nail enamel, and the workability when removing the nail enamel are optimized.
• the nail enamel remover of the present invention may contain components (other components) other than the polyvinylpyrrolidone (A), the oxygen-containing low-molecular-weight organic solvent (B1), and dimethyl carbonate (B2) as long as the effects of the present invention are not impaired.
• the nail enamel remover of the present invention may contain a lower monohydric alcohol as an auxiliary solvent for compatibilizing the polyvinylpyrrolidone (A) with the oxygen-containing low-molecular-weight organic solvent (B1) and dimethyl carbonate (B2).
• the lower monohydric alcohol is preferably a monohydric alcohol having 1 to 4 carbon atoms. Specific examples of the lower monohydric alcohol include methanol, ethanol, n-propanol, i-propanol, n-butanol, i-butanol, n-pentanol, i-pentanol, n-hexanol, i-hexanol, 2-ethylhexanol, etc.
• the content of the lower monohydric alcohol in the nail enamel remover of the present invention is preferably 40% by mass or less, more preferably 30% by mass or less, and even more preferably 20% by mass or less, from the viewpoint of compatibility between the polyvinylpyrrolidone (A) and the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2).
• the lower limit is not particularly limited, but is preferably 3% by mass or more, more preferably 5% by mass or more, and even more preferably 8% by mass or more.
• the content of the lower monohydric alcohol in the nail enamel remover of the present invention is preferably 3% by mass or more and 40% by mass or less, more preferably 5% by mass or more and 30% by mass or less, and even more preferably 8% by mass or more and 20% by mass or less.
• the nail enamel remover of the present invention may further contain fumed silica.
• the content of fumed silica in the nail enamel remover of the present invention is preferably 1% by mass or more, more preferably 2% by mass or more, and even more preferably 3% by mass or more.
• the upper limit is preferably 8% by mass or less, more preferably 6% by mass or less, and even more preferably 4% by mass or less.
• the content of fumed silica in the nail enamel remover of the present invention is preferably 1% by mass or more and 8% by mass or less, more preferably 2% by mass or more and 6% by mass or less, and even more preferably 3% by mass or more and 4% by mass or less.
• the nail enamel remover of the present invention may contain a nail protective agent.
• nail protective agents include hydrocarbon oils such as vaseline and squalane, vegetable oils such as jojoba oil and olive oil, fatty acids such as stearic acid and oleic acid, higher alcohols such as cetanol and oleyl alcohol, polyoxyethylene sorbitan fatty acid esters, glycols such as propylene glycol, 1,3-butylene glycol, isoprene glycol, and polyethylene glycol, and polyhydric alcohols such as glycerin.
• hydrocarbon oils such as vaseline and squalane
• vegetable oils such as jojoba oil and olive oil
• fatty acids such as stearic acid and oleic acid
• higher alcohols such as cetanol and oleyl alcohol
• polyoxyethylene sorbitan fatty acid esters polyoxyethylene sorbitan fatty acid esters
• glycols such as propylene glycol, 1,3-butylene glycol,
• the content of the nail protective agent in the nail enamel remover of the present invention is preferably 10% by mass or less, more preferably 5% by mass or less, and even more preferably 3% by mass or less, from the viewpoint of protecting the nails without inhibiting the effects of the present invention.
• the lower limit is not particularly limited, but is preferably 0.5% by mass or more.
• the content of the nail protective agent in the nail enamel remover of the present invention is preferably 0.5% by mass or more and 10% by mass or less, more preferably 0.5% by mass or more and 5% by mass or less, and even more preferably 0.5% by mass or more and 3% by mass or less.
• the nail enamel remover of the present invention may contain an antioxidant.
• the antioxidant is not particularly limited, but tocopherol acetate is preferred from the standpoints of safety and availability.
• the content of the antioxidant in the nail enamel remover of the present invention is preferably 5% by mass or less, more preferably 3% by mass or less, from the viewpoint of preventing oxidation of the remover without inhibiting the effects of the present invention.
• the lower limit is not particularly limited, but is preferably 0.5% by mass or more.
• the content of the antioxidant in the nail enamel remover of the present invention is preferably 0.5% by mass or more and 5% by mass or less, more preferably 0.5% by mass or more and 3% by mass or less.
• the nail enamel remover of the present invention may contain an amount of water that does not inhibit the solubility of polyvinylpyrrolidone (A) or the volatility of the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2).
• the water content in the nail enamel remover of the present invention is preferably 10% by mass or less, more preferably 7% by mass or less.
• the nail enamel remover of the present invention is preferably in the form of a gel from the viewpoint of forming a coating.
• the nail enamel remover of the present invention can effectively remove, particularly, the base coat portion of light-cured nail cosmetics such as soft gel nails. It can also effectively remove non-light-cured nail cosmetics such as nail enamel.
• PVP Polyvinylpyrrolidone
• PVP1 "Pittscol K-90" (K value: 92-96, weight average molecular weight: 1,200,000), manufactured by Daiichi Kogyo Seiyaku Co., Ltd.
• PVP2 "Pittscol K-50” (K value: 48-52, weight average molecular weight: 250,000), manufactured by Daiichi Kogyo Seiyaku Co., Ltd.
• the remover film is almost not sticky inside, and does not adhere to the remover tool.
• the remover film is slightly sticky inside, and almost does not adhere to the remover tool.
• 3 The remover film is slightly sticky inside, and adheres slightly to the remover tool.
• 2 The remover film is slightly sticky inside, and adheres relatively to the remover tool.
• 1 The remover film is quite sticky inside, and adheres quite to the remover tool.
• (3) Film-forming test The gel sample was polished in the same manner as in the peeling test. The remover was applied to the polished gel sample, and the polyvinylpyrrolidone film formed on the air side surface of the remover was evaluated by touching with fingers after leaving it for 1 minute, 5 minutes, and 15 minutes.
• strong film means a film having a sufficient thickness
• weak film means a film having a certain thickness
• the nail enamel remover of the Examples had the amounts of the oxygen-containing low molecular weight organic solvent (B1) and dimethyl carbonate (B2) and their mass ratio (B1/B2) in the appropriate range, and achieved good results in stripping, removal workability, film-forming properties, and application properties (Examples 1 to 9).
• the nail enamel remover of the examples has the amounts of polyvinylpyrrolidone (A), oxygen-containing low molecular weight organic solvent (B1), and dimethyl carbonate (B2) in the appropriate range, and has achieved good results in peelability, removal workability, film-forming properties and coating properties (Examples 10 to 16).

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• 2023
  • 2023-09-13 WO PCT/JP2023/033306 patent/WO2024228271A1/ja not_active Ceased
  • 2023-09-13 JP JP2025518096A patent/JPWO2024228271A1/ja active Pending
  • 2023-09-19 TW TW112135689A patent/TW202444333A/zh unknown

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