WO2024063602A1 - Dispositif à base de gravimétrie destiné à diluer et distribuer un échantillon - Google Patents

Dispositif à base de gravimétrie destiné à diluer et distribuer un échantillon Download PDF

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Publication number
WO2024063602A1
WO2024063602A1 PCT/KR2023/014505 KR2023014505W WO2024063602A1 WO 2024063602 A1 WO2024063602 A1 WO 2024063602A1 KR 2023014505 W KR2023014505 W KR 2023014505W WO 2024063602 A1 WO2024063602 A1 WO 2024063602A1
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WIPO (PCT)
Prior art keywords
sample
sample container
strong acid
stock solution
dilution
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PCT/KR2023/014505
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English (en)
Korean (ko)
Inventor
송영철
노예철
김정택
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한국화학연구원
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Publication of WO2024063602A1 publication Critical patent/WO2024063602A1/fr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

Definitions

  • the present invention relates to a sample dilution and dispensing device.
  • Sample pretreatment is essential for qualitative and quantitative analysis using inductively coupled plasma atomic emission spectroscopy (ICP-AES) or mass spectrometry (ICP-MS).
  • ICP-AES inductively coupled plasma atomic emission spectroscopy
  • ICP-MS mass spectrometry
  • the sample pretreatment process is a process to liquefy the sample.
  • concentration of the sample is adjusted to set conditions (ranging from ppm to several percent).
  • sample dilution based on the volumetric method has a high synthetic standard uncertainty, so sample dilution based on the gravimetric method is preferable for precise analysis.
  • sample pretreatment process involves measuring and checking the weight on a scale and manually diluting the sample, it is a process that takes more than 10 times more time than instrumental analysis and more than twice as much time as interpreting the analysis data. Additionally, the use of strong acids may expose researchers to acids or acid gases.
  • the problem to be solved according to an embodiment of the present invention is to automatically dispense and dilute samples during the pretreatment process, and in particular, to ensure safety by separating the dilution work from the researcher and the dilution of the sample based on a weight method using a precision scale. It includes promoting
  • the gravimetry-based sample dilution and dispensing device is divided into a plurality of space units, so that each space includes a base portion where the sample dilution and dispensing process is performed, and at least one It includes a driving arm for holding a sample container, a driving module for moving the sample container to each space of the base portion, a pump module for injecting a stock solution or weak acid into the sample container, and a weight of the sample container. It may include a weight measurement module that measures and records the weight measurement results.
  • control unit that controls the operation of the driving module or generates a control message to control the pump module according to preset sample dilution conditions and dispensing order.
  • control unit may receive the weight measurement result from the weight measurement module and feedback control at least one of the driving module and the pump module based on the weight measurement result.
  • the base portion includes a sample holder including a sample holder on which the sample container can be mounted, and the sample holder includes an undiluted sample line containing an undiluted solution sample and a plurality of conduits containing samples diluted by concentration.
  • a dilution sample line may be included.
  • the base part may include a shaker part in which the driving arm shakes the diluted solution a predetermined number of times before dispensing the stock solution or when a strong acid is added to the sample container and diluted.
  • the driving module is connected to the driving arm and may further include a moving unit that moves the driving arm to each space of the base using at least three axes.
  • the pump module includes a stock solution injection unit for injecting a stock solution into the sample container and a weak acid nozzle section for injecting weak acid into the sample container, and the stock solution injection section and the weak acid nozzle section respond to the control message from the control unit. Based on this, the stock solution injection unit may be opened and closed or the weak acid nozzle unit may be opened and closed.
  • the stock solution injection unit may further include a pipette coupling portion at the bottom to which a pipette tip capable of transferring the stock solution is detachably coupled.
  • the stock solution injection unit injects the stock solution into the sample container based on the set sample dilution conditions, and the control unit injects the stock solution when the weight measurement result reaches a preset target weight. can be controlled to stop.
  • the strong acid nozzle unit injects the strong acid into the sample container based on the set sample dilution conditions, and the control unit, when the weight measurement result reaches the preset target weight, the strong acid nozzle unit injects the strong acid. can be controlled to stop.
  • the sample can be automatically dispensed and diluted during the pretreatment process, thereby protecting researchers from risks resulting from acid treatment work.
  • preprocessing time can be reduced by automatically storing the sample weight and performing automatic dispensing according to the dilution ratio.
  • Figure 1 is a diagram showing a sample dilution and dispensing device based on the gravimetric method according to an embodiment of the present invention.
  • Figure 2 is a block diagram showing the control unit of a gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • Figure 3 is a diagram showing the overall configuration including a gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • Figure 4 is a diagram showing a driving module of a gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • Figure 5 is a diagram showing the weight measurement module of the sample dilution and dispensing device based on the gravimetric method according to an embodiment of the present invention.
  • Figure 6 is a diagram showing the shaker part of the sample dilution and dispensing device based on the gravimetric method according to an embodiment of the present invention.
  • Figure 7 is a diagram showing the nitric acid nozzle and pump module of the gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • Figure 8 is a diagram showing the capping part of the sample dilution and dispensing device based on the gravimetric method according to an embodiment of the present invention.
  • Figure 9 is a diagram showing a sample holder of a weight method-based sample dilution and dispensing device according to an embodiment of the present invention.
  • Figure 10 is a diagram showing the pipette rack part of the gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • Figure 11 is a diagram showing the pipette removal part of the gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • expressions such as “A or B,” “at least one of A or/and B,” or “one or more of A or/and B” may include all possible combinations of the items listed together.
  • “A or B,” “at least one of A and B,” or “at least one of A or B” (1) includes at least one A, (2) includes at least one B, or (3) It can refer to all cases including both at least one A and at least one B.
  • One embodiment of the present invention relates to a gravimetric-based sample dilution and dispensing device.
  • Figure 1 is a diagram showing a sample dilution and dispensing device based on the gravimetric method according to an embodiment of the present invention.
  • the gravimetry-based sample dilution and dispensing device 10 includes a base unit 100, a drive module 200, a pump module 300, and a weight measurement module 400. ) and a control unit 500.
  • the gravimetric-based sample dilution and dispensing device 10 preprocesses samples for qualitative and quantitative analysis using inductively coupled plasma atomic emission spectroscopy (ICP-AES) or mass spectrometry (ICP-MS). This is a device for automatically dispensing and diluting samples during the process.
  • ICP-AES inductively coupled plasma atomic emission spectroscopy
  • ICP-MS mass spectrometry
  • the base unit 100 is divided into a plurality of space units, so that sample dilution and dispensing processes are performed in each space.
  • the driving module 200 may move to each position of the base unit 100 according to the dispensing process and perform dilution and dispensing processes at each position.
  • the base portion 100 of the gravimetry-based sample dilution and dispensing device 10 includes a sample holder 110, a shaker part 120, and a strong acid part 130. ), a measuring part 140, a capping/decapping part 150, a strong acid nozzle part 160, a pipette rack part 170, and a pipette removal part 180.
  • Figure 1 shows that the base unit 100 according to an embodiment of the present invention is divided into a plurality of spaces according to each dispensing process.
  • the location and size of each partition are not limited to this, and the dispensing process and sequence are not limited to this. Changes are possible depending on.
  • the sample holder 110 includes a sample holder 111 on which the sample container 20 can be mounted.
  • the sample holder 111 is intended to hold a plurality of sample containers 20, may be formed in a flat shape, and may include a sliding member to be movable in the vertical and plane directions.
  • the sample holder 111 includes a plurality of through holes on the inside, and the sample container 20 is inserted into the through holes.
  • the shaker part 120 is provided so that the driving arm shakes the diluted solution a predetermined number of times before dispensing the stock solution or when strong acid is added to the sample container and diluted.
  • the strong acid part 130 is provided so that the nitric acid solution is placed.
  • the pump module 300 can be moved to the strong acid part 130 to previously contain nitric acid that can be added to the sample container of the pump module 300.
  • the measurement part 140 includes a weight measurement module 400 and can measure the weight of the sample container 20.
  • the weight measurement module 400 can measure the weight of the sample container and record the weight measurement result.
  • the weight measurement module 400 may be a precision scale, and the gravimetry-based sample dilution and dispensing device measures the weight of the sample container and dilutes the stock solution with a strong acid to increase the concentration of the sample solution. It can be adjusted to specified conditions (ranging from ppm to several percent).
  • pretreatment of the sample was performed by placing the sample in a graduated vial and injecting nitric acid using a pipette or syringe.
  • nitric acid using a pipette or syringe.
  • most of these tasks were performed by people, and some automated devices were used.
  • the problem is dilution based on volume. Because the volume of the liquid changes depending on the surrounding temperature, if diluted based on volume, it is difficult to accurately meet the concentration conditions of the sample.
  • the sample dilution and dispensing device based on the gravimetric method can accurately adjust the concentration conditions of the sample regardless of the surrounding temperature and environment by adjusting the concentration of the sample based on the gravimetric method.
  • the capping/decapping part 150 is provided to close or open the cap on the top of the sample container before and after the strong acid is injected into the sample container 20.
  • the capping/decapping part 150 may be divided into a capping part 150a and a decapping part 150b.
  • the driving module 200 opens the cap of the sample container at the capping/decapping part 150 and moves to the strong acid nozzle part 160, which will be described later.
  • the strong acid is injected, it returns to the capping/decapping part 150. After moving and closing the cap of the sample container, it moves to the shaker part 120.
  • the strong acid nozzle part 160 is provided to be connected to a strong acid nozzle so that the pump module 300 can inject strong acid into the sample container.
  • a nitric acid solution is used as a strong acid, but other acids may be used, and as a diluted solution, not only a nitric acid solution but also other acids, alkaline solutions, distilled water, etc. may be used.
  • the pipette rack part 170 is provided so that a pipette tip capable of transferring a stock solution is detachably coupled to the bottom of the pump module 300.
  • the stock solution may be prepared in advance in the sample holder 110, and when a pipette tip capable of transferring the stock solution is coupled to the bottom of the pump module 300, the drive module 200 uses the pipette.
  • the stock solution can be injected into the sample container.
  • the pipette removal part 180 is provided to disconnect the pipette tip after the stock solution is injected into the sample container.
  • the driving module 200 moves the sample container to each space of the base part.
  • the driving module 200 includes a driving arm 210 and a moving unit 220.
  • the driving arm 210 may hold at least one sample container 20.
  • the driving arm 210 may include a finger portion with one or more fingers, and pincer grasping and wrapping can be performed selectively or sequentially.
  • the sample container can be fixed and moved to each space of the base portion without a separate configuration for inserting the sample container.
  • the moving unit 220 is connected to the driving arm 210 and can move the driving arm to each space of the base using at least three axes.
  • the moving unit 220 may include a rail and a motor (not shown), and includes a first rail installed along the X-axis direction, a second rail installed along the Y-axis direction, and a third rail installed along the Z-axis direction. May include rails.
  • the driving arm 210 can move to each space of the base along the rail by driving a motor (not shown).
  • the driving arm can be moved using at least three axes, so the sample container 20 can be moved left and right, up and down, and forward and backward.
  • the pump module 300 injects a stock solution or strong acid into the sample container.
  • the pump module 300 includes a strong acid nozzle unit 310 and an undiluted solution injection unit 320.
  • the strong acid nozzle part 310 injects strong acid into the sample container based on the set sample dilution conditions.
  • the strong acid nozzle part 160 is connected to the pump module 300 to inject strong acid into the sample container, the nozzle is connected to the strong acid nozzle part 160. You can use this to inject strong acid into the sample container.
  • the stock solution injection unit 320 injects the stock solution into the sample container based on the set sample dilution conditions.
  • the drive module (200) The stock solution can be injected into the sample container using a pipette.
  • the stock solution injection unit and the strong acid nozzle unit are opened and closed or the strong acid nozzle unit is opened and closed after the sample container moves to the strong acid nozzle part 160 or the pipette rack part 170 based on the control message from the controller.
  • the nozzle part can be opened and closed.
  • the control unit 500 may control the operation of the drive module or generate a control message to control the pump module according to preset sample dilution conditions and dispensing order.
  • the control unit 500 is described in detail in FIG. 2 below.
  • Figure 2 is a block diagram showing the control unit of a gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • control unit 500 of the gravimetry-based sample dilution and dispensing device 10 includes a processor 510, a memory 520, and a communication unit 530.
  • the control unit 500 controls the operation of the drive module or generates a control message to control the pump module according to preset sample dilution conditions and dispensing order.
  • the processor 510 receives the weight measurement result from the weight measurement module 400 and feedback controls at least one of the driving module 200 and the pump module 300 based on the weight measurement result.
  • control unit 500 controls the drive module 200 and the pump module 300 according to the dilution operation sequence.
  • the driving module 200 of the gravimetry-based sample dilution and dispensing device removes the empty sample container from the sample holder 110 and then caps it from the capping/decapping part 150. Open, place an empty sample container on the measurement part 140, and set the zero point.
  • the pump module 300 moves the pipette tip from the pipette rack part 170 based on the preset first dilution ratio. Connect and inject the stock solution into the sample container.
  • the measurement part 140 measures the weight of the sample container, and if the weight measurement result reaches a preset target weight, the control unit 500 controls the stock solution injection unit to stop administering the stock solution.
  • the weight measurement module 400 records the weight measurement results.
  • the pump module 300 injects the diluent (nitric acid) into the sample container from the strong acid nozzle part 160 based on the preset target ratio.
  • the measurement part 140 measures the weight of the sample container, and if the weight measurement result reaches a preset target weight, the control unit 500 controls the strong acid nozzle unit to stop administering the strong acid.
  • the weight measurement module 400 records the weight measurement results.
  • the driving module 200 takes the sample container 20 out of the weighing module 400, closes the cap in the capping/decapping part 150, and mixes the diluent in the shaker part 120. Afterwards, it is placed in the sample holder 110.
  • the memory 520 stores the weight measurement results transmitted from the weight measurement module 400, and is divided into three types: flash memory type, hard disk type, multimedia card micro type, Card-type memory (e.g., SD or It may include at least one type of computer-readable storage medium among (Only Memory), PROM (Programmable Read-Only Memory), magnetic memory, magnetic disk, and optical disk.
  • flash memory type e.g., hard disk type
  • multimedia card micro type e.g., SD or It may include at least one type of computer-readable storage medium among (Only Memory), PROM (Programmable Read-Only Memory), magnetic memory, magnetic disk, and optical disk.
  • the communication unit 530 can transmit the generated control message to the driving module 200 and the pump module 300, and can receive preset sample dilution conditions and dispensing order from the outside.
  • Figure 3 is a diagram showing the overall configuration including a gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • the gravimetry-based sample dilution and dispensing device 10 includes a base unit 100, a drive module 200, a pump module 300, and a weight measurement module 400.
  • the control unit 500 may further include a nitric acid tank and recovery storage box 600 and an automatically opening and closing acid gas exhaust port 700.
  • control unit 500 may be located at the bottom of the base unit 100 and the driving module 200.
  • Figure 4 is a diagram showing a driving module of a gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • the driving module 200 moves the sample container to each space of the base part.
  • the driving module 200 includes a driving arm 210 and a moving unit 220.
  • the driving arm 210 may hold at least one sample container 20.
  • the driving arm 210 may include a finger portion with one or more fingers, and pincer grasping and wrapping can be performed selectively or sequentially.
  • the sample container can be fixed and moved to each space of the base portion without a separate configuration for inserting the sample container.
  • the moving unit 220 is connected to the driving arm 210 and can move the driving arm to each space of the base using at least three axes.
  • the moving unit 220 may include a rail and a motor (not shown), and includes a first rail 220a installed along the X-axis direction, a second rail 220b installed along the Y-axis direction, and a Z-axis direction. It may include a third rail 220c installed along.
  • the driving arm 210 can move to each space of the base along the rail by driving a motor (not shown).
  • the driving arm can be moved using at least three axes, so the sample container 20 can be moved left and right, up and down, and forward and backward.
  • the pump module 300 is connected to the driving arm 210 and can move integrally with the movement of the driving module 200.
  • the stock solution injection and the strong acid injection can be performed by replacing the strong acid nozzle connection and the pipette connection.
  • Figure 5 is a diagram showing the weight measurement module of the sample dilution and dispensing device based on the gravimetric method according to an embodiment of the present invention.
  • the weight measurement module 400 can measure the weight of the sample container and record the weight measurement result.
  • the weight measurement module 400 may be a scale, and the gravimetric method-based sample dilution and dispensing device determines the concentration of the sample solution by diluting the stock solution with a strong acid while measuring the weight of the sample container. It can be adjusted according to conditions (ranging from ppm to several percent).
  • the weight measurement module 400 includes a space portion 410 in which a sample container can be contained in the inner central portion.
  • the driving module 200 places the sample container 20 in the space 410, places the sample container 20 on the weight measurement module 400, and sets the zero point. Match.
  • Figures 5 (b) and (c) show, as an example, the pump module 300 connecting a pipette and injecting a stock solution into a sample container.
  • the control unit 500 controls the stock solution injection unit to stop administering the stock solution.
  • Figure 6 is a diagram showing the shaker part of the sample dilution and dispensing device based on the gravimetric method according to an embodiment of the present invention.
  • the shaker part 120 is provided so that the driving arm shakes the diluted solution a predetermined number of times before dispensing the stock solution or when strong acid is added to the sample container and diluted.
  • the shaker part 120 includes a fixing part 121 at the inner central portion to which one side of the sample container can be fixed.
  • the driving module 200 can fix the sample container 20 to the fixing part 121, and shaker part 120 with one side of the sample container 20 fixed. ), the sample container 20 can mix the diluted solution.
  • Figure 6 (c) shows an example of the driving module 200 fixing the sample container 20 to the fixing part 121 of the shaker part 120.
  • the driving arm 210 of the driving module 200 can be fixed to the fixing part 121 of the shaker part 120 while pressing both sides of the sample container 20 with the robot chuck 211.
  • Figure 7 is a diagram showing the nitric acid nozzle and pump module of the gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • the pump module 300 is connected to the drive arm 210 and can move integrally with the movement of the drive module 200, and the bottom It may include a strong acid nozzle unit 310 that injects strong acid into the sample container.
  • the strong acid nozzle unit 310 of the pump module 300 may be connected to the recovery hose 311, and after injecting the strong acid into the sample container, the recovery hose 311 Strong acids can be discharged to the outside.
  • the pump module 300 may be connected to the strong acid supply hose 312, and strong acid may be injected into the pump module through the strong acid supply hose 312.
  • the pump module 300 is moved to the strong acid part 130 to pre-contain nitric acid that can be added to the sample container, and the pump module 300 is moved from the strong acid nozzle part 160 to the sample container.
  • a strong acid nozzle may be connected to inject strong acid into the container.
  • the strong acid nozzle when connected, it moves toward the sample container 20 and injects strong acid into the sample container 20.
  • Figure 8 is a diagram showing the capping part of the sample dilution and dispensing device based on the gravimetric method according to an embodiment of the present invention.
  • the capping/decapping part 150 may include a fastening portion 151 that is fastened to the sample container.
  • the driving arm 210 fixes the cap of the sample container, and after the sample container is engaged with the fastening part 151, the cap is opened or closed by rotation.
  • Figure 9 is a diagram showing a sample holder of a weight method-based sample dilution and dispensing device according to an embodiment of the present invention.
  • the sample holder 110 includes a sample holder 111 on which the sample container 20 can be mounted.
  • the sample holder 111 is intended to hold a plurality of sample containers 20, may be formed in a flat shape, and may include a sliding member to be movable in the vertical and plane directions.
  • the sample holder 111 includes a plurality of through holes on the inside, and the sample container 20 is inserted into the through holes.
  • the sample holder 110 includes a sample holder 111 on which the sample container 20 can be mounted.
  • the sample holder 111 may include a stock solution sample line 111a containing stock solution samples and a plurality of dilution sample lines 111b containing samples diluted by a plurality of concentrations. .
  • the stock solution may be prepared in advance in the stock solution sample line 111a of the sample holder 110, and when a pipette capable of transferring the stock solution is coupled to the bottom of the pump module 300, the drive module ( 200) can inject the stock solution into the sample container using a pipette.
  • the driving module 200 takes the sample container 20 out of the weight measurement module 400, closes the cap on the capping/decapping part 150, and removes the diluent from the shaker part 120. After mixing, it is placed in the sample holder 110, and at this time, it is placed in the dilution sample line 111b.
  • the dilution sample line 111b is provided as a plurality of lines and can be separated differently depending on the dilution concentration.
  • Figure 10 is a diagram showing the pipette rack part of the gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • the pipette rack part 170 includes a pipette storage unit 171, and a plurality of pipettes 30 are stored in an upright position in the pipette storage unit 171. .
  • the stock solution injection unit 320 further includes a pipette coupling portion at the bottom to which the pipette tip 30 capable of transferring the stock solution is detachably coupled, and the pipette tip 30 is coupled.
  • the driving module 200 can move to the stock solution sample line 111a of the sample holder 110, contain the stock solution using a pipette, and then inject the stock solution into the sample container.
  • Figure 11 is a diagram showing the pipette removal part of the gravimetry-based sample dilution and dispensing device according to an embodiment of the present invention.
  • the pipette removal part 180 is provided to disconnect the pipette tip after the stock solution is injected into the sample container.
  • the pipette removal part 180 includes a pipette recovery unit 181 that can recover the pipette tip 30.

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Abstract

Un mode de réalisation de la présente invention concerne un dispositif à base de gravimétrie destiné à diluer et distribuer un échantillon, comprenant : une partie de base divisée en une pluralité d'unités d'espace pour effectuer un processus de dilution et de distribution d'un échantillon dans chaque espace ; un module d'entraînement comprenant un bras d'entraînement destiné à maintenir au moins un récipient d'échantillon et déplacer le récipient d'échantillon vers chaque espace de la partie de base ; un module de pompe destiné à injecter une solution mère ou introduire un acide fort dans le récipient d'échantillon ; et un module de mesure de poids destiné à mesurer le poids du récipient d'échantillon et enregistrer le résultat de mesure de poids.
PCT/KR2023/014505 2022-09-23 2023-09-22 Dispositif à base de gravimétrie destiné à diluer et distribuer un échantillon WO2024063602A1 (fr)

Applications Claiming Priority (2)

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KR10-2022-0120587 2022-09-23
KR1020220120587A KR20240041502A (ko) 2022-09-23 2022-09-23 무게법 기반의 시료 희석 및 분주 장치

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KR20140082756A (ko) * 2011-09-25 2014-07-02 테라노스, 인코포레이티드 다중분석을 위한 시스템과 방법
US20200209273A1 (en) * 2018-01-10 2020-07-02 Hitachi High-Technologies Corporation Automatic Analysis Apparatus
KR102247819B1 (ko) * 2020-10-21 2021-05-04 한국지질자원연구원 Icp-aes 분석을 위한 시료 희석 및 분주 장치

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970045193U (ko) * 1995-12-22 1997-07-31 원자흡광 분석기의 시료농도 자동 희석장치
KR19980039891U (ko) * 1996-12-20 1998-09-15 신창식 아이시피를 이용한 광석류 정량분석용 자동 시료 전처리 장치
KR20140082756A (ko) * 2011-09-25 2014-07-02 테라노스, 인코포레이티드 다중분석을 위한 시스템과 방법
US20200209273A1 (en) * 2018-01-10 2020-07-02 Hitachi High-Technologies Corporation Automatic Analysis Apparatus
KR102247819B1 (ko) * 2020-10-21 2021-05-04 한국지질자원연구원 Icp-aes 분석을 위한 시료 희석 및 분주 장치

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