WO2023098776A8 - 一种中药组合物在制备治疗神经炎药物中的用途 - Google Patents

一种中药组合物在制备治疗神经炎药物中的用途 Download PDF

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WO2023098776A8
WO2023098776A8 PCT/CN2022/135766 CN2022135766W WO2023098776A8 WO 2023098776 A8 WO2023098776 A8 WO 2023098776A8 CN 2022135766 W CN2022135766 W CN 2022135766W WO 2023098776 A8 WO2023098776 A8 WO 2023098776A8
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radix
chinese medicine
traditional chinese
medicine composition
neuritis
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PCT/CN2022/135766
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English (en)
French (fr)
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WO2023098776A1 (zh
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张贵民
孙成磊
姚景春
关永霞
马庆文
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山东新时代药业有限公司
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Priority to KR1020247008522A priority Critical patent/KR20240048013A/ko
Priority to EP22900580.6A priority patent/EP4431107A1/en
Publication of WO2023098776A1 publication Critical patent/WO2023098776A1/zh
Publication of WO2023098776A8 publication Critical patent/WO2023098776A8/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
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    • A61K36/238Saposhnikovia
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
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    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Abstract

一种治疗神经炎的中药组合物。所述中药组合物主要由羌活、独活、茯苓、防风、荆芥、川芎、桔梗、柴胡、前胡、枳壳、甘草制备而成。所述中药组合物可明显缓解大鼠面神经炎的面部麻痹、运动障碍等相关症状,显著提高大鼠术后侧面神经中VEGFb、VEGFR1及VEGFR2蛋白的表达,促进损伤后轴突的恢复和再生。
PCT/CN2022/135766 2021-12-03 2022-12-01 一种中药组合物在制备治疗神经炎药物中的用途 WO2023098776A1 (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020247008522A KR20240048013A (ko) 2021-12-03 2022-12-01 신경염 치료제 조제 중 한약 조성물의 용도
EP22900580.6A EP4431107A1 (en) 2021-12-03 2022-12-01 Application of traditional chinese medicine composition in preparation of drugs for treating neuritis

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Application Number Priority Date Filing Date Title
CN202111468002.XA CN116211924B (zh) 2021-12-03 2021-12-03 一种中药组合物在制备治疗神经炎药物中的用途
CN202111468002.X 2021-12-03

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WO2023098776A1 WO2023098776A1 (zh) 2023-06-08
WO2023098776A8 true WO2023098776A8 (zh) 2024-06-20

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EP (1) EP4431107A1 (zh)
KR (1) KR20240048013A (zh)
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108201592A (zh) 2016-12-17 2018-06-26 河南开物科技服务有限公司 柴胡牵正制剂
CN114073730A (zh) * 2020-08-14 2022-02-22 鲁南制药集团股份有限公司 一种预防或治疗空调综合征的中药组合物
CN112386635A (zh) * 2020-09-23 2021-02-23 鲁南制药集团股份有限公司 荆防制剂在制备治疗新冠后遗症药物中的应用及其制备方法

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CN116211924B (zh) 2024-03-15
EP4431107A1 (en) 2024-09-18
WO2023098776A1 (zh) 2023-06-08
CN116211924A (zh) 2023-06-06
KR20240048013A (ko) 2024-04-12

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