WO2023095587A1 - 自動分析装置 - Google Patents
自動分析装置 Download PDFInfo
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- WO2023095587A1 WO2023095587A1 PCT/JP2022/041064 JP2022041064W WO2023095587A1 WO 2023095587 A1 WO2023095587 A1 WO 2023095587A1 JP 2022041064 W JP2022041064 W JP 2022041064W WO 2023095587 A1 WO2023095587 A1 WO 2023095587A1
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- Prior art keywords
- automatic analyzer
- tip
- dispensing
- unit
- container holding
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- 238000001514 detection method Methods 0.000 claims abstract description 40
- 238000005406 washing Methods 0.000 claims abstract description 17
- 239000003153 chemical reaction reagent Substances 0.000 claims description 65
- 239000000523 sample Substances 0.000 claims description 43
- 239000007788 liquid Substances 0.000 claims description 24
- 238000004140 cleaning Methods 0.000 claims description 7
- 238000007599 discharging Methods 0.000 claims description 6
- 238000012544 monitoring process Methods 0.000 abstract 2
- 230000007246 mechanism Effects 0.000 description 59
- 230000005856 abnormality Effects 0.000 description 11
- 230000007704 transition Effects 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 238000011109 contamination Methods 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000007723 transport mechanism Effects 0.000 description 1
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
- G01N2035/1013—Confirming presence of tip
Definitions
- the present invention relates to an automatic analyzer.
- Automated analyzers are configured to dispense specimens and reagents using disposable dispensing tips for the purpose of preventing contamination of reagents and specimens in order to achieve accurate analysis.
- the pipetting tip is attached to the pipetting mechanism for each pipetting operation of the pipetting mechanism, and after the pipetting operation is completed, the tip is removed and discarded. Since attachment/detachment occurs for each dispensing operation, there is concern that attachment/detachment of the dispensing tip may fail and the tip may fall off during the dispensing operation.
- Patent Document 1 proposes an automatic analyzer that has a configuration for confirming whether or not a dispensing tip is attached to a dispensing mechanism during analysis operation.
- Patent Document 1 discloses a configuration in which a dispensing tip is attached to a dispensing mechanism, and whether or not the dispensing tip is attached during an analysis operation is detected by a sensor that monitors the movement trajectory of the dispensing mechanism. ing.
- An object of the present invention is to provide a low-cost automatic analyzer without reducing throughput.
- one sensor is arranged to monitor the movement trajectory of the pipetting mechanism, and the sensor is arranged so that the end point of the sample/reagent aspiration operation in the dispensing operation overlaps with the start point of the aspirated liquid ejection operation. By operating , it is possible to detect with one sensor whether or not the dispensing tip is attached to the dispensing nozzle.
- a low-cost automatic analyzer can be configured without reducing throughput.
- FIG. 1 is an overall schematic diagram of an automatic analyzer according to Example 1.
- FIG. FIG. 4 is a diagram for explaining the positional relationship between the moving path of the specimen/reagent dispensing mechanism of the device according to the actual example 1 and other components. 4 is a flowchart for explaining the operation of the specimen/reagent dispensing mechanism in the analysis operation of the automatic analyzer of embodiment 1;
- FIG. 4 is a diagram for explaining the positional relationship between a sensor for detecting a dispensing tip and a specimen/reagent dispensing mechanism of the automatic analyzer of Example 1;
- FIG. 4 is a view for explaining the positional relationship between a sensor for detecting a dispensing chip and a washing tank of the automatic analyzer of Example 1;
- FIG. 1 is an overall schematic diagram of the automatic analyzer 100 of Example 1.
- the automatic analyzer 100 comprises a control section 1, an input section 102 and a display section 103.
- the control unit 101 is a computer that controls the entire operation of the automatic analyzer 100 including a specimen/reagent dispensing mechanism 107, which will be described later. or a mouse.
- TIP pipetting tip
- it is configured so that the reagent can be sucked, and the sucked liquid can be discharged to the reaction container RC installed in the incubator 109 by a transport mechanism (not shown).
- This analysis device 100 further includes a chip mounting/discarding section 110 as a disposal position and a sensor 112 as a detection section.
- the sensor 112 is a detector for detecting whether or not a dispensing tip is attached to or removed from the dispensing nozzle 1070 of the specimen/reagent dispensing mechanism 107, as will be described later.
- the method of the sensor 112 is not limited, but the detection principle and the like are not critical as long as the presence of the dispensing tip can be detected.
- the sensor 112 is composed of a light emitting section 112-1 that generates light and a light receiving section 112-2 that receives reflected scattered light.
- the specimen/reagent dispensing mechanism 107 includes an arm 1071 that can rotate around a rotation shaft 1070 and a dispensing nozzle 1072 attached to the arm 1071 as a probe.
- the specimen/reagent pipetting mechanism 107 is configured such that the pipetting nozzle 1072 can move along the arc-shaped movement path Rm by rotating the arm 1071 .
- the suction units 104S/105R, the detection unit 112S composed of the sensor 112, the discharge units 109P1/109P2, and the tip attachment/disposal unit 110 are arranged and configured as shown in FIG.
- the specimen/reagent dispensing mechanism 107 dispenses specimens and reagents using one dispensing tip as described later.
- a washing tank 111 is installed on the movement route Rm as a mechanism for washing the dispensing tip to prevent contamination before and after the aspiration operation of each sample and reagent.
- FIG. 3 shows an example of the dispensing operation of the sample/reagent dispensing mechanism 107.
- an example of the dispensing operation of the sample/reagent dispensing mechanism 107 is as follows. Mounting of the dispensing tip in the tip mounting/discarding section 110 (S1). Aspiration of the first liquid in the specimen/reagent rack aspiration section 105R (S3). Aspiration of the second liquid in the specimen/reagent rack aspiration unit 104S (S5). Discharge of the sucked liquid in the discharge section 109P1/2 (S7). Move to detection unit 112S (S8). Disposal of the dispensing tip in the tip attachment/disposal unit 110 (S9). are performed in the order of
- the chip detection unit 112S configured by the sensor 112 in FIG. 2 coincides with the end point Rm-S of the reciprocating motion in the operation composed of steps S1, S3, and S5 corresponding to the dispensing and aspirating operation of the specimen/dispensing mechanism 107. are arranged to Further, the operation S7 is configured so that the operation start point of the dispensing/discharging operation S7 of the specimen/dispensing mechanism 107 is Rm-S. By adding the operation of S8, the sensor 112 detects the presence or absence of the dispensing tip configured in the dispensing nozzle 1072 in each of the operations of S1, S3, S5, and S7. By arranging the sensors 112 as described above and executing the operation S8, one sensor 112 can detect the dispensing tip.
- the end point Rm-S of the reciprocating motion of the dispensing and aspirating operation S100 may be placed at any position on the movement path Rm-S, but as shown in FIG. placement is optimal.
- the operation of the sample/dispensing mechanism 107 can be divided into the operation on the sample/reagent rack 106 side from Rm-S and the operation on the incubator 109 side from Rm-S. / Reagent aspiration operation and specimen/reagent ejection operation can be performed in the shortest distance.
- the control signal from the control unit 101 causes the dispensing nozzle 1072 attached to the sample/reagent dispensing mechanism 107 to move to the initial position. , along the movement route Rm to the tip mounting/discarding section 110, where the dispensing tip is mounted. (S1) After that, the dispensing nozzle 1072 moves in the reverse direction (arrow X) along the movement path Rm, passes through the discharge section 109P1/2, reaches the suction section 105R, and sucks the first liquid from the sample reagent container 104.
- FIG. (S2) During the transition from S1 to S3, when the nozzle 1072 passes through the detection unit 112S composed of the sensor 112, the sensor 112 detects whether or not the dispensing tip at the tip of the dispensing nozzle 1072 is attached. If attachment of the dispensing tip is detected, it is determined that the dispensing operation is normal, and the dispensing operation is continued. If the dispensing tip is not detected, it is determined that an abnormality has occurred in the dispensing operation, that is, that the attachment of the dispensing tip has failed, the operation of the sample/reagent dispensing mechanism 107 is stopped, and an abnormality is notified on the display unit 103. .
- the specimen/reagent dispensing mechanism 107 After the first liquid is aspirated by the aspirator 105R, the specimen/reagent dispensing mechanism 107 returns to the movement path Rm in the opposite direction (the direction of the arrow) and reaches Rm-S, which is the end point of the reciprocating motion of the operation S100. After that, after washing in the washing tank 111 installed on the moving route Rm, it moves in the opposite direction (direction of the arrow) again, reaches the aspirating part 104S, and aspirates the second liquid from the sample reagent container 104. (S5) Since the detection unit 112S is arranged so as to coincide with Rm-S, the sensor 112 detects whether or not the dispensing tip is attached during the transition from S3 to S5.
- the liquid After washing in the tank 111, the liquid passes through the detecting section 112S, reaches the liquid discharging section 109P1 or 109P2, and is sucked, and is discharged into the reaction vessel RS installed in the discharging section. (S7)
- the sensor 112 detects whether or not the dispensing tip is attached. If attachment of the dispensing tip is detected, it is judged that the dispensing operation is performed normally, and the dispensing operation is continued.
- the operation of the sample/reagent dispensing mechanism 107 is stopped, and the display unit 103 is notified of the abnormality.
- the sample/dispensing mechanism 107 After ejecting the liquid from the liquid ejecting part 109P1 or 109P2, the sample/dispensing mechanism 107 returns to the moving path Rm in the opposite direction, moves to the reciprocating motion end point Rm-S, and performs chip detection.
- the sensor 112 detects whether or not the dispensing tip is attached. If attachment of the dispensing tip is not detected, it is determined that the disposing operation of the dispensing tip has been completed normally, and the dispensing operation ends. When the dispensing tip is detected, it is determined that an abnormality has occurred in the dispensing operation, that is, the dispensing tip has failed to be discarded, the operation of the sample/reagent dispensing mechanism 107 is stopped, and an abnormality is notified on the display unit 103. .
- washing tank 111 may be placed anywhere on the movement route Rm, it is optimal to place it between the sample/reagent rack 106 and the incubator 109 as shown in FIG. By aligning the position of the washing tank 111 with the end point Rm-S of the reciprocating motion of the specimen/reagent pipetting mechanism 107, the pipetting operation of the specimen/reagent pipetting mechanism 107 can be performed in the shortest possible time.
- FIG. 4 shows the mutual positional relationship between the specimen/reagent pipetting mechanism 107 and the sensor 112 .
- FIG. 4 shows an example in which a light reflection sensor is applied, and the sensor for detecting the dispensing tip may be arranged so as to satisfy the following two conditions.
- a dispensing tip is attached to the tip of the dispensing nozzle 1072, and a detection signal is emitted when the dispensing nozzle 1072 is positioned at the sensor detection portion.
- a dispensing tip is not attached to the tip of the dispensing nozzle 1072, and no detection signal is generated when the dispensing nozzle 1072 is positioned at the sensor detection portion.
- a sensor positional relationship when the light reflection sensor shown in FIG. 4 is applied will be described in detail.
- the light reflection sensor is specifically arranged so as to satisfy the following conditions.
- a detection range 112SR of the sensor is located on the movement path Rm-S.
- the sensor detection range 112SR satisfies the following conditions at the height when the specimen/reagent dispensing mechanism 107 moves along the movement route Rm.
- the detection range 112SR of the sensor must not overlap the tip 1072-1 of the dispensing nozzle 1072. When the dispensing tip is attached to the dispensing nozzle 1072, the detection range 112SR of the sensor and the dispensing tip should overlap.
- the detection range 112SR of the sensor must not overlap with any mechanism other than the dispensing tip. Further, the sensor 112 is configured to be able to transmit the detection state of the sensor 112 to the control unit 101 when the control unit 101 issues a control signal for confirming the sensor state.
- FIG. 5 shows the positional relationship between the cleaning tank 111 and the sensor 112.
- the detection unit 112S configured by the sensor 112 coincides with the reciprocating motion end point Rm-S. Therefore, the positional relationship between sensor 112 and cleaning tank 111 satisfies the following conditions.
- the detection range 112SR of the sensor 112 should be located above the cleaning tank 111 in the height direction. The sensor 112 should not interfere with the movement path Rm. The detection range 112SR of the sensor 112 should not interfere with the liquid/mechanism used for cleaning in the cleaning tank 111. Sensor 112 satisfies the above sensor placement requirements.
- the area 112-P where the sensor 112 can be arranged is set so that the sensor 112 does not interfere with the moving route Rm and the detection unit 112S coincides with the reciprocating motion end point Rm-S. is a set of positions that can be placed in
- the area 112-P shown in FIG. 5 is an example when a light reflection sensor is applied. If the above conditions are met, then the placeable area is 112-P.
- the chip mounting/discarding section 110, the incubator 109, the sensor 112, the reciprocating motion end point Rm-S, and the sample/reagent rack 106 are arranged as described above. , 3, 5, 7 and S8, the sample/dispensing mechanism 107 can detect the dispensing tip by the sensor 112. FIG. Also, by aligning the end point Rm-S of the reciprocating motion with the position of the sensor 112, the operating distance of the sample/reagent dispensing mechanism 107 can be minimized. Enables detection of dispensing tips multiple times.
- the display unit 103 notifies the occurrence of the abnormality, and the specimen pipetting operation can be stopped.
- the automatic analyzer of this embodiment includes an incubator that accommodates a plurality of reaction vessels, a specimen/reagent dispensing mechanism that dispenses a specimen/reagent into each of the plurality of reaction vessels, and a specimen/reagent
- An attachment part for attaching a dispensing tip to the dispensing mechanism, an aspiration part for aspirating the specimen/reagent from the container containing the specimen/reagent using the specimen/reagent dispensing mechanism with the dispensing tip attached, and an incubator.
- a control unit for controlling the sample/reagent dispensing mechanism, the loading unit, the suction unit, the discharge unit, and the disposal unit are arranged along the moving path of the sample/reagent dispensing mechanism,
- the sensor is arranged between the suction section and the ejection section, and is controlled by the control section to return to the sensor after the liquid is ejected from the specimen/reagent dispensing mechanism into the reaction container in the ejection section.
- 100Automatic analyzer 101 control unit, 102 input unit, 103 display unit, 106 sample/reagent rack, 107 sample/reagent dispensing mechanism 107, 1070 sample/reagent dispensing mechanism rotating shaft, 1071 rotating arm, 1072 dispensing nozzle , 108 Reaction container/dispensing tip storage part, 109 Incubator, 109 P1 First discharge position, 109 P2 Second discharge position, 110 Chip mounting/disposal part, 111 Washing tank, 112 Sensor, 112 S Detection part, 112 SR Sensor detection range, 112 -P Range where the sensor can be placed.
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Abstract
Description
チップ装着/廃棄部110における分注チップの装着(S1)。
検体/試薬ラック吸引部105Rにおける第一液体の吸引(S3)。
検体/試薬ラック吸引部104Sにおける第二液体の吸引(S5)。
吐出部109P1/2における吸引した液体の吐出(S7)。
検出部112Sへの移動(S8)。
チップ装着/廃棄部110における分注チップの廃棄(S9)。
の順に行われる。
検体/試薬の分注指令が制御部101に入力部102を介して入力されると、制御部101からの制御信号により検体/試薬分注機構107に装着された分注ノズル1072は、初期位置から移動経路Rmに沿って、チップ装着/廃棄部110へ移動し、分注チップを装着される。(S1)
その後分注ノズル1072は移動経路Rmを逆方向(矢印X)に移動し、吐出部109P1/2を通過し、吸引部105Rへ到達し、第一液体を検体試薬容器104から吸引する。(S2)
このS1からS3の移行において、センサ112により構成される検出部112Sをノズル1072が通過すると、センサ112は分注ノズル1072の先端の分注チップの装着の有無を検知する。分注チップの装着が検出されれば分注動作は正常であると判断し、分注動作は継続される。分注チップが検出されない場合、分注動作に異常が発生、即ち分注チップの取り付けの失敗と判断され、検体/試薬分注機構107の動作は停止され、表示部103に異常告知がなされる。(S102)
検体/試薬分注機構107は吸引部105Rにて第一液体の吸引後、移動経路Rmを再度逆方向(矢印の方向)に戻り、動作S100の往復動作端点であるRm-Sまで到達し、その後移動経路Rm上に設置された洗浄槽111で洗浄を行った後、再度逆方向(矢印の方向)に移動し、吸引部104Sに到達し、第二液体を検体試薬容器104から吸引する。(S5)
検出部112SはRm-Sと一致するように配置されることから、S3からS5への移行においてセンサ112により分注チップが装着されているか否かを検知する。分注チップの装着が検知されれば、分注動作は正常に行われていると判断され分注動作は継続される。分注チップが検出されない場合、分注動作に異常が発生している(分注チップの脱落)と判断され、検体/試薬分注機構107の分注動作は停止され、表示部103に異常告知がなされる。(S102)
検体/試薬分注機構107は吸引部104Sで第二液体を吸引後、移動経路Rmを再度逆方向(矢印の方向)に戻り、往復動作端点Rm-S、移動経路Rm上に設置された洗浄槽111で洗浄を行った後、検出部112Sを通過し、液体吐出部109P1もしくは109P2に到達し吸引した液体を吐出部に設置された反応容器RSに吐出する。(S7)
ここで、S5からS7への移行においてセンサ112により分注チップが装着されているか否かを検知する。分注チップの装着が検知されれば、分注動作は正常に行われていると判断され分注動作は継続される。分注チップが検出されない場合、分注動作に異常が発生、即ち分注チップの脱落と判断され、検体/試薬分注機構107の動作は停止され、表示部103に異常告知がなされる。(S102)
検体/分注機構107は液体吐出部109P1もしくは109P2で液体を吐出後、移動経路Rmを再度逆方向にもどり、往復動作端点Rm-Sまで移動し、チップ検知を行う。(動作S8)
分注チップの検出部112SはRm-Sと一致するように配置されることから、動作S7から動作S8の移行においてセンサ112により分注チップが装着されているか否かを検知する。分注チップが検出されない場合、分注動作に異常が発生している(分注チップの脱落)と判断され、検体/試薬分注機構107の分注動作は停止され、表示部103に異常告知がなされる。(動作S102)
検体/試薬分注機構107が動作S8により往復動作端点Rm-Sに到達し、分注チップの装着有無を確認したのち、検体/試薬分注機構107は移動経路Rmを再度逆方向に進み、チップ装着/廃棄部110まで移動し、チップ廃棄処理を実行する。(S9)
チップ装着/廃棄部110でのチップ廃棄が完了したのち、検体/試薬分注機構107は移動経路Rmを再度逆方向に戻り、往復動作端点Rm-Sまで移動し待機する。このため、往復動作端点Rm-Sは待機部として機能する。(S11)
ここで、S9からS11への移行においてセンサ112により分注チップが装着されているか否かを検知する。分注チップの装着が検知されなければ、分注チップの廃棄動作が正常に完了したと判断され分注動作は終了する。分注チップが検出された場合、分注動作に異常が発生、即ち分注チップの廃棄失敗と判断され、検体/試薬分注機構107の動作は停止され、表示部103に異常告知がなされる。(S102)
前記した洗浄槽111は移動経路Rm上のどこに配置しても構わないが、図2に示すように検体/試薬ラック106とインキュベータ109の間に配置することが最適である。また、洗浄槽111の位置を検体/試薬分注機構107の往復動作端点Rm-Sと一致させることにより、検体/試薬分注機構107の分注動作を最短で実施することが可能となる。
分注ノズル1072の先端に分注チップが装着され、センサ検出部に分注ノズル1072が位置するとき検知信号を発する。
分注ノズル1072の先端に分注チップが未装着であり、センサ検出部に分注ノズル1072が位置するとき検知信号を発しない。
センサの検出範囲112SRが移動経路Rm-S上に位置する。
センサの検出範囲112SRが検体/試薬分注機構107が移動経路Rmを移動するときの高さにおいて、以下の条件を満たす。
センサの検出範囲112SRが、分注ノズル1072の先端部1072-1と重ならないこと。
分注ノズル1072が分注チップを装着しているとき、センサの検出範囲112SRと、分注チップが重なること。
センサの検出範囲112SRに分注チップ以外の機構が重ならないこと。
またセンサ112は、制御部101より、センサ状態を確認する制御信号が発せられた時点のセンサ112の検知状態を制御部101に送信可能な構成となっている。
センサ112の検出範囲112SRは洗浄槽111と重ならない、高さ方向上部に位置すること。
センサ112は移動経路Rmと干渉しないこと。
センサ112の検出範囲112SRは洗浄槽111での洗浄に使用される液体・機構と干渉しないこと。
センサ112は前記センサ配置の条件を満たす。
Claims (9)
- 先端にチップが装着され、該チップを介して液体を吸引及び吐出するプローブと、
前記プローブが吸引すべき液体を収容する容器を複数保持する第1容器保持部と
前記プローブが吐出すべき液体を収容する容器を複数保持する第2容器保持部と、
前記プローブの先端に前記チップが装着されているか否かを検知する検知部と、
前記プローブの動きを制御する制御部と、を備え、
前記第1容器保持部、前記検知部、前記第2容器保持部の順に配置され、
前記制御部は、前記プローブが前記第1容器保持部上で前記液体を吸引し、前記検知部を経由して、前記第2容器保持部上で該液体を吐出した後、前記検知部に戻り前記チップを検知するように制御する、
ことを特徴とする自動分析装置。 - 請求項1記載の自動分析装置であって、
前記第1容器保持部と前記第2容器保持部の間に、前記チップを洗浄する洗浄槽を備える、
ことを特徴とする自動分析装置。 - 請求項2記載の自動分析装置であって、
前記検知部は、前記洗浄槽の上部に設置される、
ことを特徴とする自動分析装置。 - 請求項2記載の自動分析装置であって、
前記プローブを待機させる待機部を備え、
前記待機部は前記検知部に位置する、
ことを特徴とする自動分析装置。 - 請求項1記載の自動分析装置であって、
前記検知部は、前記制御部より制御指令が発せられた時点の前記検知部におけるチップ検知情報を前記制御部へ送信可能である、
ことを特徴とする自動分析装置。 - 請求項1記載の自動分析装置であって、
前記プローブから前記チップを廃棄する位置である廃棄位置を備え、
前記第1容器保持部、前記検知部、前記第2容器保持部、前記廃棄位置の順に配置され、前記廃棄位置における前記チップの廃棄前に、前記検知部により前記チップの検知を可能とする、
ことを特徴とする自動分析装置。 - 請求項6記載の自動分析装置であって、
前記検知部は、光を発する光源と、前記光を検知する光検出器とを含む、
ことを特徴とする自動分析装置。 - 請求項1記載の自動分析装置であって、
前記プローブは、前記第1容器保持部に保持された吸引すべき液体を分注動作内で複数回吸引し前記第2容器保持部にて吐出することが可能である、
ことを特徴とする自動分析装置。 - 請求項8記載の自動分析装置であって、
前記吸引すべき液体は、検体及び試薬である、
ことを特徴とする自動分析装置。
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0894629A (ja) * | 1994-09-21 | 1996-04-12 | Fuji Photo Film Co Ltd | 乾式分析素子用サンプリング装置 |
JPH08146010A (ja) * | 1994-09-21 | 1996-06-07 | Hitachi Ltd | 分注装置を備えた分析装置 |
JP2005009867A (ja) * | 2003-06-16 | 2005-01-13 | Fuji Photo Film Co Ltd | 分析装置におけるノズルチップ検出装置 |
JP2006322756A (ja) * | 2005-05-17 | 2006-11-30 | Hitachi Koki Co Ltd | 自動分注装置 |
WO2019146220A1 (ja) | 2018-01-26 | 2019-08-01 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
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- 2022-11-02 EP EP22898371.4A patent/EP4439074A1/en active Pending
- 2022-11-02 CN CN202280067463.2A patent/CN118159849A/zh active Pending
- 2022-11-02 WO PCT/JP2022/041064 patent/WO2023095587A1/ja active Application Filing
- 2022-11-02 JP JP2023563595A patent/JPWO2023095587A1/ja active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0894629A (ja) * | 1994-09-21 | 1996-04-12 | Fuji Photo Film Co Ltd | 乾式分析素子用サンプリング装置 |
JPH08146010A (ja) * | 1994-09-21 | 1996-06-07 | Hitachi Ltd | 分注装置を備えた分析装置 |
JP2005009867A (ja) * | 2003-06-16 | 2005-01-13 | Fuji Photo Film Co Ltd | 分析装置におけるノズルチップ検出装置 |
JP2006322756A (ja) * | 2005-05-17 | 2006-11-30 | Hitachi Koki Co Ltd | 自動分注装置 |
WO2019146220A1 (ja) | 2018-01-26 | 2019-08-01 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
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