WO2023090477A1

WO2023090477A1 - Method for preparing cosmetic composition for ameliorating acne comprising wild-cultivated ginseng essential oil

Info

Publication number: WO2023090477A1
Application number: PCT/KR2021/016903
Authority: WO
Inventors: 조재영
Original assignee: 농업회사법인 주식회사 우리두
Priority date: 2021-11-17
Filing date: 2021-11-17
Publication date: 2023-05-25

Abstract

A method for preparing a cosmetic composition for ameliorating acne, comprising wild-cultivated ginseng essential oil, comprises the steps of: obtaining wild-cultivated ginseng essential oil by using at least one step selected from steps of steaming, freezing and vaporizing wild-cultivated ginseng, and steps of refining and recovering a gas obtained in the vaporizing step; preparing an aged wild-cultivated ginseng solution by mixing wild-cultivated ginseng with saccharides in an amount of 15-240% with respect to the weight of the wild-cultivated ginseng, and then aging the mixture; preparing a wild-cultivated ginseng extract by extracting the prepared aged wild-cultivated ginseng solution under reduced pressure; and mixing 5-10 wt% of the wild-cultivated ginseng essential oil, 5-10 wt% of the wild-cultivated ginseng extract, collagen, ethanol, glycerin, and purified water.

Description

Manufacturing method of cosmetic composition for improving acne containing wild ginseng essential oil

The present invention relates to a method for preparing a cosmetic composition for improving acne containing wild ginseng essential oil.

As research on skin science, such as differentiation of skin cells, identification of aging phenomena, and development of artificial cells, has become active, several improved functional natural cosmetics have been developed to meet these consumption trends. Interest in natural materials with various effects such as oxygen removal, collagen synthesis, and anti-wrinkle is also increasing.

Such skin is damaged due to various contaminants and stress, and skin elasticity is lowered, moisture is lost, and wrinkles may be formed. In addition, when the skin ages, it becomes difficult for the dermis to retain moisture in the skin, the skin becomes rough, and the functions of the sebaceous glands and sweat glands decrease. As a result, the sebum film is not properly formed and the protective power against skin hydration is lost, and eventually the skin becomes dry and loses its transparency, reducing the elasticity of skin proteins and forming wrinkles. In addition, the loss of moisture retention of the skin is an important factor in skin aging.

Here, acne is caused by hypersecretion of sebaceous glands due to hyperactivity of male hormones in puberty and epithelial cells of hair follicles cause dyskeratosis, resulting in clogging of hair follicles. It is known that Propionibacterium acnes, a bacterium, actively proliferates to produce free fatty acid, which stimulates hair follicles and causes inflammation called acne.

As a method for treating or mitigating acne, female hormones such as estrogen, which is a male hormone inhibitor, or antibacterial agents have been used to suppress sebum hypersecretion.

However, the method of using these female hormones may cause excessive skin inflammation and may cause many side effects. In addition, it can cure acne by promoting the discharge of sebum, but moisturizing agents and alpha-hydroxy acid (AHA) that can soften dead skin cells can dissolve the skin more than necessary, leaving scars and causing skin irritation. can cause problems with

Therefore, the object of the present invention is to improve acne, skin regeneration, skin wrinkle prevention, skin aging prevention, skin inflammation improvement, and whitening improvement by increasing the activity of enzymes contained in wild ginseng with very low skin side effects. It is to provide a method for producing a cosmetic composition for improving acne comprising a.

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil according to the present invention for achieving the above object is a process of purifying and recovering the gas obtained in the steaming process, freezing process, vaporization process, and the vaporization process of the wild ginseng. Obtaining wild ginseng essential oil using at least one process of; Preparing a fermented wild ginseng liquid by mixing 15% to 240% of sugar with the wild ginseng in an amount of 15% to 240% by weight; Preparing a wild ginseng extract by extracting the prepared wild ginseng aged liquid under reduced pressure; and mixing collagen, ethanol, glycerin, and purified water, including 5 to 10% by weight of the wild ginseng essential oil and 5 to 10% by weight of the wild ginseng extract. Since a cosmetic composition is prepared using wild ginseng essential oil and fermented wild ginseng extract, acne improvement, skin regeneration, skin wrinkle prevention, skin aging prevention, skin inflammation improvement, and whitening improvement can be improved.

Here, in the steaming process, steam at 80 to 120 ° C is treated for 5 to 20 minutes, the freezing process is performed at -50 ° C or less for 4 to 6 hours, and the vaporization process is performed at -10 to 20 ° C and vaporization is performed for 24 to 96 hours while the pressure is maintained in a vacuum state of -500 mmHg or less, and the purification and recovery process is performed at 20 ° C or less for 1 to 10 hours in a low-temperature vacuum condition. It is preferable to efficiently remove moisture from vaporized (or sublimated) gas using an essential oil recovery trap and recover vegetable essential oil.

And the step of preparing the fermented wild ginseng liquid, washing the wild ginseng with purified water to remove foreign substances; removing moisture attached to the surface of the wild ginseng; Mixing the wild ginseng with sugar, honey, sucrose, glucose, allulose, tagatose, starch syrup, oligosaccharide, fructose, and saccharide containing at least one of glucose; Mixing 5 to 15% by weight of a mineral mixture containing at least one of Ca, Mg, Cu, Zn, Na, K, Fe, P, Cl, Ge, Pt, Se based on the weight of the mixture of wild ginseng and sugars; And including the step of aging the wild ginseng mixture in which minerals and sugars are mixed to increase the activity of enzymes contained in wild ginseng for skin regeneration, preventing or improving skin wrinkles, preventing or improving skin aging, improving skin inflammation or skin It is preferable because it can provide a cosmetic composition for improving whitening.

Here, in the step of aging the wild ginseng mixture, if the extract is prepared after aging at 20 ~ 30 ° C for 20 to 24 weeks, the wild ginseng aging liquid is preferable because the skin regeneration effect can reach the optimal effect.

In addition, if the step of aging the wild ginseng extract for 1 to 4 weeks is further included, it is preferable that the antioxidant and whitening effect of the wild ginseng aged liquid can be optimal.

Here, the step of mixing the purified water further includes at least one composition from the group consisting of skin protection, skin soothing, antioxidant, wrinkle improvement, skin irritation relief, moisturizing and whitening, moisturizing, whitening, anti-aging, skin It is preferable because it can simultaneously implement tissue improvement, skin elasticity improvement, and skin soothing effect.

And the selected composition, witch hazel water 5% by weight, camellia oil 5% by weight, olive oil 1% by weight, sea buckthorn extract 5% by weight, orange oil 5% by weight, perilla leaf extract 5% by weight, hollyhock extract 1.5% by weight %, at least one of ginseng extract 5% by weight, chamomile extract 0.5% by weight, western dandelion leaf extract 0.5% by weight, licorice extract 0.5% by weight and centella asiatica extract 0.5% by weight. low, so it is desirable

Here, in the step of preparing the wild ginseng extract, when the wild ginseng is immersed in edible alcohol and eluted, the main components of wild ginseng can be efficiently extracted.

In addition, in the step of obtaining the wild ginseng essential oil, water is separated from the gas obtained through the vaporization process using an oil recovery trap, and the essential oil is purified and recovered, and the substances used in the essential oil recovery trap are non-polar vegetable oil, non-polar Animal oils, polar vegetable oils, or a mixture of at least two of these oils are very human-friendly because vegetable essential oils are refined and recovered at low temperatures, and decomposition or denaturation due to heat can be suppressed.

On the other hand, the cosmetic composition for improving acne containing wild ginseng essential oil according to the present invention for achieving the above object is prepared by any one of the above methods.

According to the present invention, side effects of the skin are very low, and by increasing the activity of enzymes contained in wild ginseng, there is an effect of improving acne, skin regeneration, skin wrinkle prevention, skin aging prevention, skin inflammation improvement, and whitening improvement.

1 is a flow chart of a method for producing a cosmetic composition for improving acne containing wild ginseng essential oil according to the present invention.

Hereinafter, a method for preparing a cosmetic composition for improving acne containing wild ginseng essential oil according to a preferred embodiment of the present invention will be described in detail with reference to the accompanying drawings.

First, wild ginseng essential oil is obtained by using at least one of the processes of purifying and recovering the gas obtained from the steaming process, freezing process, vaporization process, and gasification process of wild ginseng.

Here, in the steaming process, steam at 80 to 120 ° C is treated for 5 to 20 minutes.

The freezing process proceeds for 4 to 6 hours at -50 ° C or lower. By this process, the moisture contained inside the object is rapidly frozen.

The vaporization process is maintained at -10 to 20 ° C, and the vaporization proceeds for 24 to 96 hours in a state where the pressure is maintained in a vacuum state of -500 mmHg or less. The frozen wild ginseng is vaporized in a vacuum chamber. During the vaporization process, frozen moisture is vaporized and released from the inside of the target to the outside along with various aromatic components, and these vapors are introduced into the essential oil recovery trap to separate water and purify and recover vegetable essential oil at the rear end.

The process of refining and recovering is carried out at 20℃ or less for 1 to 10 hours. Water is separated from the gas obtained through the vaporization process using an oil recovery trap, and the essential oil is purified and recovered. The material used in the oil recovery trap is non-polar. of vegetable oils (corn, soybean, canola, olive, sunflower, palm, walnut, peanut, flax, safflower, grapeseed, avocado, hempseed, cottonseed oil, etc.), non-polar animal oils (lard, beef tallow, milk fat, etc.), polar It is a vegetable oil (macadamia, coconut, sunflower seed, castor, almond oil, etc.) or a mixture of at least two of these oils. The lipid used at this time may contain antioxidants (eg, vitamin E, selenium, etc.).

When a mixture of water and essential oil flows into a non-polar trap containing oil, the essential oil dissolves in the oil and diffuses to the top of the oil layer. At this time, when the moisture diffused by the vacuum pump at the rear is moved to the moisture recovery trap, the moisture is frozen and recovered there. As described above, when using an oil component commonly used in cosmetics as the oil contained in the trap, the oil component in the trap can be recovered as it is and used as a cosmetic component without the need to additionally separate the essential oil component. In addition, when only pure essential oil components are to be separated, the essential oil components can be separated from the trap oil components by an existing standard (or published) separation method.

The essential oil recovered as described above is separated and refined into the oil contained in the trap and the vegetable essential oil to be obtained using a fractional distillation method. At this time, the temperature of the fractional distiller is preferably in the range of 40 to 60 ° C, and the vaporized vegetable essential oil can be recovered by passing through a condenser. The temperature of the condenser at this time is preferably in the range of 0-10 ° C.

Second, after mixing 15% to 240% of the weight of the wild ginseng with sugars in the wild ginseng, it is aged to prepare a fermented wild ginseng liquid.

Here, the wild ginseng is washed with purified water to remove foreign substances and the moisture attached to the surface of the wild ginseng is removed. Saccharides containing at least one of sugar, honey, sucrose, glucose, allulose, tagatose, starch syrup, oligosaccharide, fructose, and glucose in washed and drained wild ginseng mix Mix 5 to 15% by weight of a mineral mixture containing at least one of Ca, Mg, Cu, Zn, Na, K, Fe, P, Cl, Ge, Pt, and Se relative to the weight of the mixture of wild ginseng and sugars. After aging the wild ginseng mixture mixed with minerals and sugars at 20 ~ 30 ℃ for 20 to 24 weeks, an eluate is prepared.

Here, if the sugar content is more than 70, the elution effect may be somewhat easy, but on the contrary, it tends to lower the activity of enzyme and the efficacy is lower than the optimal condition. do. As can be seen in the efficacy results, the ratio of sugar and minerals was applied according to the ratio under the premise that the active enzymes of wild ginseng are not the same. there was. Therefore, if the ratio of minerals is less than 0.1% compared to the applied saccharide, it has little influence on the activity of enzyme during the aging process, and if it is over 50%, the aging is not smooth, so it is effective and applied to cosmetic formulations. indicates an adverse effect.

Here, when the aging period is less than 20 weeks, the aging period is too short, and the elution of enzymes and phytonutrient components in the fermented wild ginseng liquid is low, so the skin regeneration effect does not appear, and when the aging period exceeds 24 weeks, skin regeneration It was confirmed that the increase in the effect was insignificant. That is, the point at which the wild ginseng aging liquid of the present invention reaches the optimum effect can be said to be 20 to 24 weeks, and since there was no contamination by bacteria during the aging process, even if it is aged beyond 24 weeks, the wild ginseng aging liquid is deteriorating. I was able to confirm that there was no problem. However, if the period exceeds 24 weeks, the yield of enzymes and phytonutrients slows down, so it is economically inefficient.

In addition, when the aging period is 20 to 24 weeks, the antioxidant and anti-wrinkle effect of the fermented wild ginseng liquid is most excellent. If the aging period exceeds 24 weeks, the yield of wild ginseng aging extract does not increase significantly compared to the increase in aging period, and the degree of improvement in the antioxidant and wrinkle improvement effects of wild ginseng aging liquid is insignificant. The aging step is preferably carried out at a temperature of 20 to 40 ° C, and when the temperature is 20 to 40 ° C, the enzymes and phytonutrient components of wild ginseng are generated and eluted without deterioration or destruction. It has the best antioxidant and anti-wrinkle effect.

Thirdly, the prepared sanyangsam extract is extracted under reduced pressure to prepare a sanyangsam extract. It can be carried out using a pressure filter or a vacuum filter, and the wild ginseng extract can be aged for 1 to 4 weeks, and it is preferable to perform it in an airtight container. When aged for less than 1 week, aging does not proceed properly, so the antioxidant and whitening effects of the fermented wild ginseng liquid are insignificant. . Here, wild ginseng may be immersed in edible alcohol to elute it. This makes it possible to obtain the extract more quickly.

Fourth, collagen, ethanol, glycerin and purified water are mixed, including 5 to 10% by weight of wild ginseng essential oil and 5 to 10% by weight of the wild ginseng extract. The mixing process here uses a high-speed homogenizer so that all components are uniformly and homogeneously mixed.

Here, at least one composition from the group consisting of skin protection, skin soothing, antioxidant, wrinkle improvement, skin irritation relief, moisturizing and whitening may be further included and mixed. As a result, moisturizing, whitening, anti-aging, skin tissue improvement, skin elasticity improvement, and skin soothing effects can be implemented at the same time. At least one is 5% by weight of witch hazel water, 5% by weight of camellia oil, 1% by weight of olive oil, 5% by weight of sea buckthorn extract, 5% by weight of orange oil, 5% by weight of perilla leaf extract, 1.5% by weight of hollyhock extract, ginseng extract 5% by weight, 0.5% by weight of chamomile extract, 0.5% by weight of western dandelion leaf extract, 0.5% by weight of licorice extract, and 0.5% by weight of Centella asiatica extract.

Here, witch hazel water was obtained by hot water extraction of witch hazel leaves (Hamamelis Virginiana (Witch Hazel) Leaf). Witch Hazel is a type of deciduous tree that lives in the subtropics and is extracted from the leaves of a tree called Poongnyeonhwa in Korean. It is used as a pore reducing, skin moisturizing and soothing ingredient. Sea buckthorn extract consists of an extract obtained by extracting active ingredients from sea buckthorn leaves and sea buckthorn fruits, respectively. Sea buckthorn extract is preferably mixed with sea buckthorn leaf extract extracted with 50% ethanol, sea buckthorn leaf extract extracted with 70% ethanol, and sea buckthorn fruit extract extracted with hot water. The leaves may be dried, cut into small pieces, put in an Erlenmeyer flask, 70% ethanol added, and then immersed at room temperature for 24 hours, followed by filtering and extraction.

Plant materials for extraction are washed with water to remove foreign substances, dried in the shade, and individually ground. An appropriate amount of solvent is added to the powder of each pulverized plant material so that it is completely immersed. Powder of each plant material Powder can be extracted using a common extraction solvent, preferably, (a) anhydrous or hydrous lower alcohol having 1 to 4 carbon atoms (eg methanol, ethanol, propanol, butanol, normal- propanol, iso-propanol and normal-butanol, etc.), (b) a mixed solvent of the lower alcohol and water, (c) acetone, (d) ethyl acetate, (e) chloroform, (f) 1,3-butylene It can be extracted using glycol, (g) hexane, (h) diethyl ether, (i) butyl acetate or (j) water, but ethanol, methanol, butanol, propanol, butylene glycol, propylene glycol, chloroform, ethyl Acetate, dichloromethane, nucleic acid, petroleum ether or diethyl ether can be used.

A cosmetic composition for improving acne containing wild ginseng essential oil can be prepared using the above method.

The cosmetic composition may further include a fatty substance, an organic solvent, a solubilizing agent, a thickening agent and a gelling agent, a softening agent, an antioxidant, a suspending agent, a stabilizer, a foaming agent, a fragrance, a surfactant, water, ionic or non-ionic. It may contain adjuvants such as ionic emulsifiers, fillers, sequestering and chelating agents, preservatives, vitamins, blocking agents, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic actives, lipid vesicles, and the like.

In addition, extracts of various plants may be included, and vegetable essential oils of Sakgi may contain β-panasinsene, cyclopropeazulene, spathulenol, alloaramandrene, *?*-selinene, isopropyllidene, isospathulenol, and the like.

In addition, vegetable essential oils may further include ginseng, sesame leaf, angelica leaf, ginseng, calamus, or licorice, including Shinyangsam, and steam, freeze, vaporize, and purify plants effective for acne such as Schisandra and lavender. It can be retrieved and used.

Claims

In the method for producing a cosmetic composition for improving acne containing wild ginseng essential oil,

Obtaining wild ginseng essential oil by using at least one of the process of purifying and recovering the gas obtained from the steaming process, freezing process, vaporization process, and gasification process of the wild ginseng;

Preparing a fermented wild ginseng liquid by mixing 15% to 240% of sugar with the wild ginseng in an amount of 15% to 240% by weight;

Preparing a wild ginseng extract by extracting the prepared wild ginseng aged liquid under reduced pressure; and

Comprising the step of mixing collagen, ethanol, glycerin and purified water, including 5 to 10% by weight of the wild ginseng essential oil and 5 to 10% by weight of the wild ginseng extract,

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil.
According to claim 1,

In the steaming process, steam at 80 to 120 ° C. is treated for 5 to 20 minutes,

The freezing process is carried out for 4 to 6 hours at -50 ° C or lower,

In the vaporization process, vaporization is performed for 24 to 96 hours in a state where the temperature is maintained at -10 to 20 ° C and the pressure is maintained in a vacuum state of -500 mmHg or less,

The purification and recovery process is performed for 1 to 10 hours at 20 ° C or less,

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil.
According to claim 1,

The step of preparing the fermented wild ginseng liquid,

Washing wild ginseng with purified water to remove foreign substances;

removing moisture attached to the surface of the wild ginseng;

Mixing the wild ginseng with sugar, honey, sucrose, glucose, allulose, tagatose, starch syrup, oligosaccharide, fructose, and saccharide containing at least one of glucose;

Mixing 5 to 15% by weight of a mineral mixture containing at least one of Ca, Mg, Cu, Zn, Na, K, Fe, P, Cl, Ge, Pt, Se based on the weight of the mixture of wild ginseng and sugars; and

Including the step of aging a wild ginseng mixture mixed with minerals and sugars,

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil.
According to claim 3,

The step of aging the wild ginseng mixture,

Preparing an eluate after aging for 20 to 24 weeks at 20 to 30 ° C.

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil.
According to claim 1,

Further comprising the step of aging the wild ginseng extract for 1 to 4 weeks,

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil.
According to claim 1,

Mixing the purified water,

Further comprising at least one composition from the group consisting of skin protection, skin soothing, antioxidant, wrinkle improvement, skin irritation relief, moisturizing and whitening,

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil.
According to claim 6,

At least one of the above

5% by weight of witch hazel water, 5% by weight of camellia oil, 1% by weight of olive oil, 5% by weight of sea buckthorn extract, 5% by weight of orange oil, 5% by weight of perilla leaf extract, 1.5% by weight of hollyhock flower extract, 5% by weight of ginseng extract , Chamomile extract 0.5% by weight, western dandelion leaf extract 0.5% by weight, licorice extract 0.5% by weight and centella asiatica extract containing at least one of 0.5% by weight,

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil.
According to claim 1,

The step of preparing the wild ginseng extract,

Eluting the wild ginseng by immersing it in edible alcohol,

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil.
According to claim 1,

The step of obtaining the wild ginseng essential oil,

Water is separated from the gas obtained through the vaporization process using an essential oil recovery trap, and the essential oil is purified and recovered,

The material used in the essential oil recovery trap is non-polar vegetable oil, non-polar animal oil, polar vegetable oil, or a mixture of at least two of these oils,

Method for producing a cosmetic composition for improving acne containing wild ginseng essential oil.
A cosmetic composition for improving acne comprising wild ginseng essential oil prepared by the method of any one of claims 1 to 9.