WO2023050521A1 - 一种组合式调控取栓装置 - Google Patents

一种组合式调控取栓装置 Download PDF

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Publication number
WO2023050521A1
WO2023050521A1 PCT/CN2021/128045 CN2021128045W WO2023050521A1 WO 2023050521 A1 WO2023050521 A1 WO 2023050521A1 CN 2021128045 W CN2021128045 W CN 2021128045W WO 2023050521 A1 WO2023050521 A1 WO 2023050521A1
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WO
WIPO (PCT)
Prior art keywords
tennis ball
proximal end
inner tube
adjustable
control
Prior art date
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PCT/CN2021/128045
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English (en)
French (fr)
Inventor
程文杰
穆磊
许永松
王孟静
郭雷辰
范文吉
武永昭
马丽丽
Original Assignee
北京泰杰伟业科技有限公司
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Application filed by 北京泰杰伟业科技有限公司 filed Critical 北京泰杰伟业科技有限公司
Priority to EP21959085.8A priority Critical patent/EP4378403A1/en
Publication of WO2023050521A1 publication Critical patent/WO2023050521A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22094—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for for crossing total occlusions, i.e. piercing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2212—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having a closed distal end, e.g. a loop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2215—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having an open distal end

Definitions

  • the present disclosure relates to the field of medical devices, in particular to a combined control thrombectomy device.
  • Stroke is an acute cerebrovascular disease that includes ischemic stroke (due to a blocked blood vessel that prevents blood from flowing into the brain) and hemorrhagic stroke (due to a sudden rupture of a blood vessel in the brain). Stroke has the characteristics of high morbidity, disability, recurrence, mortality, and cost. China is already the world's largest stroke country. The disease burden of stroke in China is growing explosively, showing trends such as younger age, relapse, frequently-occurring disease, and common disease.
  • AIS acute ischemic stroke
  • IV intravenous
  • tPA tissue plasminogen activator
  • sICH symptomatic intracerebral hemorrhage
  • the embedding process of the laser-engraved self-expandable stent takes a certain amount of time, and the thrombus cannot be taken out of the body immediately, which increases the risk of disability or even death of the patient; while the Tigertriever stent is a braided adjustable stent, but due to its simple operation, it lacks The precise size control function can easily lead to excessive control of the size of the stent. When the size of the stent is much larger than the expected blood vessel, it will cause serious damage to the blood vessel and bring the risk of bleeding.
  • the purpose of the present disclosure is to provide a combined control and thrombectomy device to at least partially solve the above technical problems.
  • a combined control thrombectomy device including:
  • a delivery unit the delivery unit includes an outer tube, an inner tube, a control core wire and a guide spring; the inner tube is passed through the outer tube, the proximal end of the inner tube is connected to the control unit, the The inner tube is configured to slide in the outer tube under the adjustment of the control unit; the control core wire is passed through the inner tube, and the proximal end of the control core wire is connected to the control unit.
  • the control core wire is configured to slide in the inner tube under the adjustment of the control unit;
  • a collection basket the proximal end of the collection basket is fixedly connected to the distal end of the outer tube;
  • An adjustable tennis ball the proximal end of the adjustable tennis ball is fixedly connected to the distal end of the inner tube, and the distal end of the adjustable tennis ball is connected to the proximal end of the guide spring;
  • the adjustable tennis ball is inside, and the distal end of the control core wire is fixedly connected with the proximal end of the guide spring, so that the adjustable tennis ball can expand or contract under the action of the control core wire.
  • control unit includes a housing and a sliding mechanism
  • Adjustment buttons are arranged on the shell.
  • scale marks are provided on the housing, and the scale marks are used to display position information of the adjustment buttons.
  • the sliding mechanism is a direct connection mechanism, a screw mechanism, a rack and pinion mechanism, a ratchet mechanism or a link mechanism.
  • the adjustment method of the adjustment button includes sliding, rotating or dialing.
  • the adjustment buttons include a first adjustment button and a second adjustment button
  • the first adjustment button is connected to the proximal end of the inner tube through the sliding mechanism, and is used to adjust the relative position between the adjustable tennis ball and the collection basket;
  • the second adjustment button is connected to the proximal end of the control core wire through the sliding mechanism, and is used for adjusting the expansion or contraction of the adjustable tennis ball.
  • the collection basket is a single-layer basket or a multi-layer basket
  • the mesh at the proximal end of the collection basket has a larger pore size than the mesh at the distal end of the collection basket.
  • the collection basket is made of nickel-titanium metal wires or cobalt-chromium alloy wires cross-woven;
  • the collection basket has a cylindrical shape in a compressed state.
  • the adjustable tennis ball is made of nickel-titanium metal wire or cobalt-chromium alloy wire cross-woven;
  • the adjustable tennis ball is cylindrical in a compressed state
  • the adjustable tennis ball is in the shape of a sphere, an ellipsoid, a disc, a cone, a cylinder or a sausage in an expanded state.
  • the nickel-titanium metal wire has a circular, oval or square cross section.
  • the guide spring is wound from Nitinol wire
  • the distal end of the guide spring is provided with a ball cap structure.
  • the proximal end of the collection basket is provided with a first visible mark
  • the proximal end of the adjustable tennis ball is provided with a second developing mark
  • the distal end of the adjustable tennis ball is provided with a third visible mark.
  • the adjustable tennis ball is a single or multiple tennis balls in series.
  • An embodiment of the present disclosure provides a combined control thrombus removal device.
  • the control core wire of the delivery unit is adjusted through the adjustment button of the control unit, so that the tennis ball can be adjusted to expand and open after passing through the thrombus, and then continue to be adjusted through the adjustment button.
  • the retractable tennis ball and the captured thrombus can be retracted into the collection basket and withdrawn from the body together.
  • the stimulation to the blood vessel is reduced to prevent the occurrence of secondary thrombus during withdrawal.
  • FIG. 1 is a schematic structural view of a combined control thrombectomy device provided by an embodiment of the present disclosure
  • Fig. 2 is a schematic diagram of a collection basket and an adjustable tennis ball in a compressed state provided by an embodiment of the present disclosure
  • Fig. 3 is a schematic diagram of a collection basket provided by an embodiment of the present disclosure and an adjustable tennis ball in an unfolded state;
  • Fig. 4 is a schematic diagram of the relative position of the adjustable tennis ball and the collection net basket provided by the embodiment of the present disclosure
  • Fig. 5 is a schematic diagram of the fully recovered adjustable tennis ball provided by the embodiment of the present disclosure.
  • FIG. 6 is a schematic cross-sectional structure diagram of a double-layer collection basket provided by an embodiment of the present disclosure
  • Fig. 7 is a schematic cross-sectional structure diagram of a single-layer collection net basket provided by an embodiment of the present disclosure
  • Fig. 8 is a schematic diagram of the mesh density of the weaved structure of the collection basket provided by an embodiment of the present disclosure
  • Fig. 9 is a schematic diagram of the planar structure path of the weaving path of the collection basket and the metal wire of the adjustable tennis ball provided by the embodiment of the present disclosure
  • Fig. 10 is one of the structural schematic diagrams of the adjustable tennis ball provided by the embodiment of the present disclosure.
  • Fig. 11 is the second structural schematic diagram of the adjustable tennis ball provided by the embodiment of the present disclosure.
  • Fig. 12 is the third structural schematic diagram of the adjustable tennis ball provided by the embodiment of the present disclosure.
  • Fig. 13 is the fourth structural schematic diagram of the adjustable tennis ball provided by the embodiment of the present disclosure.
  • Fig. 14 is the fifth structural schematic diagram of the adjustable tennis ball provided by the embodiment of the present disclosure.
  • Fig. 15a is the sixth structural schematic diagram of the adjustable tennis ball provided by the embodiment of the present disclosure.
  • Figure 15b is a schematic diagram of the sixth open state of the structure schematic diagram of the adjustable tennis ball provided by the embodiment of the present disclosure.
  • Fig. 16a is one of the working schematic diagrams of a combined control thrombectomy device provided by an embodiment of the present disclosure
  • Fig. 16b is the second working schematic diagram of a combined control thrombectomy device provided by an embodiment of the present disclosure
  • Fig. 16c is the third working schematic diagram of a combined control thrombectomy device provided by an embodiment of the present disclosure.
  • Fig. 16d is the fourth working schematic diagram of a combined control thrombectomy device provided by an embodiment of the present disclosure.
  • Fig. 16e is the fifth working schematic diagram of a combined control thrombectomy device provided by an embodiment of the present disclosure.
  • An embodiment of the present disclosure provides a combined control and thrombectomy device, including a control unit, a delivery unit, a collection basket and an adjustable tennis ball;
  • the delivery unit includes an outer tube, an inner tube, a control core wire and a guide spring;
  • the inner tube can be placed outside the Sliding in the tube, controlling the sliding of the core wire in the inner tube, the proximal end of the collection basket is fixedly connected with the distal end of the outer tube, and the proximal end of the tennis ball is fixedly connected with the distal end of the inner tube;
  • the control unit includes an adjustment button, through The adjustment button adjusts the inner tube to realize the position adjustment of the adjustable tennis ball, and adjusts the control core wire to realize the state adjustment of the adjustable tennis ball; the expansion of the adjustable tennis ball realizes the capture of the thrombus and withdraws the thrombus into the collection basket and collects it. Withdraw from the body together. Through the segmented thrombus removal device, there is no need to match the length of the
  • distal or proximal are used in the following descriptions regarding the position or orientation of the end relative to the treating physician's or medical interventional physician's hand-held end.
  • the “distal end” is a position far away from the direction of the hand-held end of the doctor or interventional doctor.
  • Proximal is the position close to the direction of the doctor's or interventionalist's hand-held end.
  • connection may mean a direct connection between the two, or an indirect connection through an intermediary, both of which should be understood as included in the "connection”.
  • Fig. 1 is a schematic structural view of a combined control and thrombectomy device provided by an embodiment of the present disclosure
  • Fig. 2 is a schematic view of a collection basket and an adjustable tennis ball provided by an embodiment of the present disclosure in a compressed state
  • Fig. 3 is an embodiment of the present disclosure
  • the combined thrombectomy device includes: a control unit 1 , a delivery unit 2 , a collection basket 3 and an adjustable tennis ball 4 .
  • the control unit 1 includes a housing 11 and a sliding mechanism (not shown in the figure), and the housing 11 is provided with an adjustment button 12, wherein the adjustment button 12 includes a first adjustment button and a second adjustment button.
  • a scale mark 13 is provided, and the scale mark 13 is used to display the position information of the adjustment button 12 .
  • the delivery unit 2 includes an outer tube 21, an inner tube 22, a control core wire 23 and a guide spring 24, wherein the inner tube 22 is penetrated in the outer tube 21, and the proximal end of the inner tube 22 is connected with the adjustment button 12 through a sliding mechanism, and the inner tube 22 is connected with the adjustment button 12 through a sliding mechanism.
  • the tube 22 can slide in the outer tube 21, and the adjustment button 12 can adjust the inner tube 22 through the sliding mechanism, so that the inner tube 22 can slide in the outer tube 21; the control core wire 23 is installed in the inner tube 22, and the control core wire 23 The proximal end is connected with the adjustment button 12 through a sliding mechanism, the control core wire 23 can slide in the inner tube 22, and the adjustment button 12 realizes the adjustment of the control core wire 23 through the sliding structure, so that the control core wire 23 can be adjusted in the inner tube 22 Swipe in.
  • the far-end of collecting net basket 3 has first opening, and the proximal end of collecting net basket 3 is provided with the first developing mark 31, and the near-end of collecting net basket 3 is fixedly connected with the far-end of outer tube 21, makes collecting net basket 3 can Under the action of the outer tube 21, it moves to a corresponding position in the blood vessel.
  • the proximal end of the adjustable tennis ball 4 is provided with a second developing mark 41, and the proximal end of the adjustable tennis ball 4 is fixedly connected with the distal end of the inner tube 22.
  • the fixed connection method can be riveting or bonding, and the adjustable tennis ball 4
  • the far end of the ball is provided with a third developing mark 42, and the far end of the adjustable tennis ball 4 is connected with the near end of the guide spring 24.
  • the control core wire 23 is threaded in the adjustable tennis ball 4, and the distal end of the control core wire 23 is fixedly connected with the distal end of the third developing mark 42 and the proximal end of the guide spring 24, so that the control core wire 23 realizes The expansion or contraction of the tennis ball 4 can be regulated.
  • the sliding mechanism is a motion conversion mechanism.
  • the sliding mechanism can be a direct connection structure, a spiral structure, a rack and pinion structure, a ratchet mechanism or a linkage mechanism.
  • the sliding mechanism can realize the conversion of the adjustment button 12 into the inner tube 22 or the control core. Wire 23 moves, and then realizes the adjustment to the position and state of adjustable tennis ball 4.
  • the adjustment mode of the adjustment button 12 can be sliding, rotating or dialing.
  • the adjustment button 12 includes a first adjustment button and a second adjustment button, wherein the first adjustment button is connected with the proximal end of the inner tube 22 through a sliding mechanism, and the adjustment of the inner tube 22 by the sliding mechanism realizes the adjustment of the collection basket.
  • the second adjustment button is connected with the proximal end of the control core wire 23 through the sliding mechanism, and the adjustment of the control core wire 23 through the sliding mechanism can control the state of the adjustable tennis ball 4 and realize the adjustable Expansion or contraction of tennis ball 4.
  • FIG. 4 is a schematic diagram of the relative position of the adjustable tennis ball and the collection net basket provided by the embodiment of the present disclosure. As shown in FIG. The position of the tennis ball 4 relative to the collection basket 3 can be adjusted, so that the combined control thrombus retrieval device can adapt to thrombus of different lengths, and realize the grasping of thrombus of different lengths.
  • the collection basket 3 can be a single-layer basket or a multi-layer basket.
  • the collection basket 3 is in a compressed state during delivery, and can automatically expand and open when it is pushed out from the catheter.
  • the collection net basket 3 is made of metal wires 33 cross-woven, and is cylindrical in a compressed state.
  • the weaving structure of the distal end of the collection net basket 3 is denser, and the weaving structure of the proximal end is relatively sparse.
  • a back opening structure 32 is provided at the first opening to reduce the stimulation of the metal wire to the blood vessels;
  • a U-shaped surrounding structure can be adopted , to avoid irritation to the inner wall of the blood vessel at the opening of the basket.
  • the adjustable tennis ball 4 is cross-braided by metal wires 33 and is cylindrical in a compressed state.
  • the adjustable tennis ball 4 can expand into a spherical, ellipsoidal, disc, conical, cylindrical or Sausage shaped.
  • the adjustable tennis ball 4 can be a single tennis ball, or can be formed by connecting multiple tennis balls in series.
  • the guide spring 24 is a soft segment of a spring structure made of nickel-titanium alloy wire, and a soft ball cap structure 241 is provided at the far end of the guide spring 24 .
  • the first developing mark 31 , the second developing mark 41 and the third developing mark 42 provided by the embodiment of the present disclosure are all X-ray-opaque marks.
  • the collecting basket 3 and the controllable tennis ball 4 can be observed through the developing marks.
  • the metal wire weaving the collection net basket 3 and the adjustable tennis ball 4 also adopts a developing wire, so that the working state of the collection net basket 3 and the adjustable tennis ball 4 can be observed under X-ray.
  • Fig. 5 is a schematic diagram of the fully recovered adjustable tennis ball provided by the embodiment of the present disclosure. As shown in Fig. 5, when the adjustable tennis ball 4 is recycled into the collection basket 3, it can pass through the second developing mark 41 and the third developing mark 42 for observation, the specific position of the adjustable tennis ball 4 in the collection basket 3 can be observed, and the device can be recovered easily after the thrombus is captured.
  • Fig. 6 is a schematic cross-sectional structure diagram of a double-layer collection basket provided by an embodiment of the present disclosure. As shown in Fig. 6, the double-layer structure collects the basket 3, and its distal end adopts an arc-shaped design, which can reduce the weight of the collection basket 3. The stimulation of the distal end to the inner wall of the blood vessel can better protect the blood vessel.
  • Fig. 7 is the schematic diagram of the section structure of the single-layer collection net basket provided by the embodiment of the present disclosure.
  • the distal end of 3 can better protect the blood vessel from the stimulation of the inner wall of the blood vessel.
  • the size of the single-layer structure of the collection basket 3 is small, which can reduce the structural size of the overall delivery unit 2, which is more conducive to narrower blood vessels. used within.
  • the U-shaped structure at the far end has a developing effect, which is conducive to observing the far end position of the collection basket 3 .
  • Sparse mesh is conducive to the passage of thrombus, so that the negative pressure suction device can suck out the thrombus.
  • Sparse mesh can reduce the cutting of thrombus and reduce the risk of thrombus rupture; denser mesh at the far end can prevent thrombus from escaping.
  • FIG. 9 is a schematic diagram of the planar structure path of the weaving path of the collection basket and the metal wire of the adjustable tennis ball provided by the embodiment of the present disclosure; the collection basket 3 and the adjustable tennis ball 4 are all woven by metal wire 33, wherein the metal wire 33 can be nickel-titanium metal wire or cobalt-chromium alloy wire.
  • the cross-section of the nickel-titanium wire can be circular, oval or square.
  • the weaving mode of metal wire 33 adopts the cross weaving mode, as shown in Figure 9, has used a kind of 2 pressure 2 cross weaving mode in Figure 9, promptly adopts the mode that every two metal wires 33 carry out cross weaving, also can adopt Press 1 or 3 press 3 cross weaving method, the collection basket 3 obtained by cross weaving of different numbers of metal wires has different mesh structure and radial force, and technicians can adjust it according to actual needs.
  • Fig. 10 is one of the structural schematic diagrams of the adjustable tennis ball provided by the embodiment of the present disclosure; as shown in Fig. 10 , the adjustable tennis ball 4 has a pear-shaped structure, which is more conducive to embedding thrombus and has a larger contact area with the thrombus. It is more conducive to the detachment of the thrombus from the vessel wall; at the same time, the proximal end of the structure is smaller, which is more conducive to entering the collection basket 3 when the thrombus is recovered.
  • Figure 11 is the second schematic diagram of the structure of the adjustable tennis ball provided by the embodiment of the present disclosure. It is beneficial to embed the thrombus and play a role in fixing the thrombus, and the large ball structure at the distal end can better prevent the thrombus from escaping.
  • Fig. 12 is the third structural schematic diagram of the adjustable tennis ball provided by the embodiment of the present disclosure.
  • the cross section of the adjustable tennis ball 4 is a double-sided fishhook cross section.
  • the adjustable tennis ball 4 of this structure collects thrombus, It can form an embedded structure with the thrombus, and the fishhook structure can better peel off the thrombus on the inner wall of the blood vessel, and can also recover the thrombus debris to prevent the small thrombus from escaping.
  • Fig. 13 is the fourth schematic diagram of the structure of the adjustable tennis ball provided by the embodiment of the present disclosure. As shown in Fig. 13, the adjustable tennis ball 4 of this structure can better adapt to the blood vessel and reduce the internal friction between the adjustable tennis ball 4 and the blood vessel The thrombus is effectively separated from the blood vessel and pulled into the collection basket 3.
  • Fig. 14 is the fifth schematic diagram of the structure of the adjustable tennis ball provided by the embodiment of the present disclosure.
  • the adjustable tennis ball 4 of this structure is a hand-basket structure with an opening at the proximal end and a dense net at the far end structure, after expansion, it can be attached to the inner wall of the blood vessel, and the thrombus and the adjustable tennis ball 4 form a whole, so that a lasso-type sliding device is formed between the thrombus and the adjustable tennis ball 4, which is more conducive to the peeling between the thrombus and the blood vessel , can effectively reduce the stimulation of the adjustable tennis ball 4 to the inner wall of blood vessels.
  • Figure 15a is the sixth structural schematic diagram of the adjustable tennis ball provided by the embodiment of the present disclosure
  • Figure 15b is a schematic diagram of the open state of the sixth structural schematic diagram of the adjustable tennis ball provided by the embodiment of the present disclosure, as shown in Figures 15a and 15b, the structure Combined with the spring-type hinge mechanism, the adjustable tennis ball 4 forms a sunken net plate structure after opening, so that the adjustable tennis ball 4 and the hinge mechanism form a corresponding thrombus collection adjustable tennis ball.
  • the advantage of the multi-hinge mechanism is that it can be connected through the hinge. Point-limited control can regulate the structure and shape changes of tennis ball 4.
  • the outer diameter of the outer tube 21 is 0.3-2mm, and the inner diameter is 0.2-1.8mm; the outer diameter of the inner tube 22 is 0.2-1.6mm, and the inner diameter is 0.1- 1.4mm; the diameter of the control core wire 23 is 0.08 ⁇ 1mm; the outer diameter of the collection basket 3 is 1 ⁇ 10mm; the diameter of the braided metal wire of the collection basket 3 is 0.01 ⁇ 0.16mm; 0.6-10mm; the diameter of the braided metal wire of the adjustable tennis ball 4 is 0.01-0.16mm.
  • the control core wire 23 By rotating or pushing and pulling the adjustment button 12 to pull the control core wire 23, the control core wire 23 tightens the adjustable tennis ball 4 to realize the expansion and opening of the adjustable tennis ball 4, and then controls the inner tube through the adjustment button 12 to realize the retraction of the adjustable tennis ball 4,
  • the captured thrombus is collected into the collection basket 3 and withdrawn together into the catheter, and then withdrawn from the body as a whole to realize the removal of the thrombus in the blood vessel.
  • Figures 16a-16e are working schematic diagrams of a combined control thrombectomy device provided by an embodiment of the present disclosure, as shown in Figures 16a-16e, in Figure 16a, the catheter 7 is a common interventional treatment
  • the delivery catheter used in this method is to deliver the thrombus removal device to the thrombus 6 in the blood vessel 5 through the catheter 7.
  • the inner tube 22 can be adjusted by the adjustment button 12 by observing the visible mark. Regulation tennis ball 4 is released conduit 7.
  • control core wire 23 is adjusted by the adjustment button 12 to realize the expansion of the controllable tennis ball 4 at the original position.
  • the catheter 7 is retracted.
  • Fig. 16c the catheter 7 is withdrawn to the proximal end of the thrombus 6, but at this time the collection basket 3 is still inside the catheter 7 and is in an unopened state.
  • Fig. 16d continue to withdraw the catheter 7 to the proximal end of the collection basket 3, so that the collection basket 3 is completely exposed in the blood vessel 5, at this time, the collection basket 3 is automatically opened, and the thrombus 6 is removed together with the adjustable tennis ball 4. to capture.
  • the inner tube 22 is adjusted by the adjustment button 12 to drive the adjustable tennis ball 4 to retreat, and the captured thrombus 6 is collected into the collection basket 3 and withdrawn from the body together with the collection basket 3 .
  • An embodiment of the present disclosure provides a combined control thrombus removal device.
  • the inner tube of the delivery unit and the control core wire are adjusted through the adjustment button of the control unit, so that the tennis ball can be adjusted to expand and open after passing through the thrombus, and then continue to be performed by the adjustment button. Adjustment, the adjustable tennis ball and the captured thrombus are retracted into the collection basket and withdrawn from the body together.
  • the segmented thrombus removal device there is no need to match the length of the thrombus, and at the same time, it reduces the stimulation to the blood vessels and prevents the occurrence of secondary thrombus during withdrawal.

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Abstract

一种组合式调控取栓装置，包括：控制单元(1)；输送单元(2)，包括外管(21)、内管(22)、控制芯丝(23)和导向弹簧(24)；内管(22)穿设在外管(21)内，近端与控制单元(1)相连接，配置为在控制单元(1)的调节下实现在外管(21)内滑动；控制芯丝(23)穿设在内管(22)内，近端与控制单元(1)相连接，配置为在控制单元(1)的调节下实现在内管(22)内滑动；收集网篮(3)，近端与外管(21)的远端固定连接；可调控网球(4)，近端与内管(22)的远端固定连接，远端与导向弹簧(24)的近端相连接；控制芯丝(23)穿设在可调控网球(4)内，远端与导向弹簧(24)的近端固定连接。在使用时，通过旋转或推拉调节按钮(12)调节内管(22)从而实现可调控网球(4)的位置调节，同时调节控制芯丝(23)从而实现可调控网球(4)在穿过病变部位后膨胀打开，从而实现对血栓(6)的捕获并随装置取出。

Description

一种组合式调控取栓装置
本申请要求于2021年09月29日提交中国专利局、申请号为202111151414.0、发明名称为“一种组合式调控取栓装置”的中国专利申请的优先权。
技术领域
本公开涉及医疗器械领域，尤其涉及一种组合式调控取栓装置。
背景技术
脑卒中是一种急性脑血管疾病，包括缺血性卒中(因血管阻塞导致血液不能流入大脑)和出血性卒中(由于脑部血管突然破裂)。脑卒中具有发病率高、致残率高、复发率高、致死率高、成本高等特点。中国已经是全球卒中的第一大国。中国卒中疾病负担有爆发式增长的态势，并呈现出年轻化、易复发、多发病、常见病等趋势。
急性缺血性中风(AIS)的第一批治疗方法是静脉(IV)注射组织纤溶酶原激活剂(tPA)进行溶栓，治疗结果表明，尽管症状性脑出血(sICH)的发生率略有增加，但在症状出现后3小时内静脉注射tPA可改善3个月时的功能独立性。然而，通过溶栓实现大血管闭塞再通的成功率很低，这就促使了机械血栓切除术的发展，并涌现了一大批取血栓装置。
然而，目前市面上大部分的取血栓装置都是通过支架嵌入血栓，然后将支架和血栓一起取出体外，例如美敦力的Solitaire取栓支架，强生的分段式取栓支架Embotrap系列支架和Rapid Medical的可调控Tigertriever支架等。一方面，这些支架在嵌入血栓的过程中，血栓容易 破碎，从而导致血栓碎块逃逸，随血液流动到血管远端，形成新的血栓；另一方面，Solitaire和Embotrap支架为激光雕刻自膨式支架，在取栓过程中，极易对血管壁造成损伤。此外，激光雕刻自膨式支架的嵌入血栓过程需要一定的时间，不能立即将血栓取出体外，增加患者残疾甚至死亡的风险；而Tigertriever支架虽为编织可调控支架，但由于其调控操作简单，缺乏精准尺寸调控功能，容易造成支架尺寸调控过度，支架尺寸远大于预期血管时，将导致血管严重损伤，带来出血风险。
发明内容
为了克服现有技术的不足，本公开目的是提供一种组合式调控取栓装置，以至少部分解决上述的技术问题。
为了实现上述目的，本公开提供了一种组合式调控取栓装置，包括：
控制单元；
输送单元，所述输送单元包括外管、内管、控制芯丝和导向弹簧；所述内管穿设在所述外管内，所述内管的近端与所述控制单元相连接，所述内管配置为在所述控制单元的调节下实现在所述外管内滑动；所述控制芯丝穿设在所述内管内，所述控制芯丝的近端与所述控制单元相连接，所述控制芯丝配置为在所述控制单元的调节下实现在所述内管内滑动；
收集网篮，所述收集网篮的近端与所述外管的远端固定连接；
可调控网球，所述可调控网球的近端与所述内管的远端固定连接，所述可调控网球的远端与所述导向弹簧的近端相连接；所述控制芯丝穿设在所述可调控网球内，并且所述控制芯丝的远端与所述导向弹簧的近端固定连接，以使所述可调控网球在所述控制芯丝的作用下实现膨胀或收缩。
在一些方案中，所述控制单元包括外壳和滑动机构；
所述外壳上设置有调节按钮。
在一些方案中，所述外壳上设置有尺度标记，所述尺度标记用于显示所 述调节按钮的位置信息。
在一些方案中，所述滑动机构为直连机构、螺旋机构、齿轮齿条机构、棘轮机构或连杆机构。
在一些方案中，所述调节按钮的调节方式包括滑动、转动或拨动。
在一些方案中，所述调节按钮包括第一调节按钮和第二调节按钮；
所述第一调节按钮通过所述滑动机构与所述内管的近端相连接，用于调节所述可调控网球与所述收集网篮之间的相对位置；
所述第二调节按钮通过所述滑动机构与所述控制芯丝的近端相连接，用于调节所述可调控网球的膨胀或收缩。
在一些方案中，所述收集网篮为单层网篮或多层网篮；
所述收集网篮近端处的网眼的孔径大于所述收集网篮远端处的网眼的孔径。
在一些方案中，所述收集网篮由镍钛金属丝或钴铬合金丝交叉编织而成；
所述收集网篮在压缩状态下呈圆柱形。
在一些方案中，所述可调控网球由镍钛金属丝或钴铬合金丝交叉编织而成；
所述可调控网球在压缩状态下呈圆柱形；
所述可调控网球在膨胀状态下呈球形、椭球形、盘形、锥形、圆柱形或香肠形。
在一些方案中，所述镍钛金属丝的截面为圆形、椭圆形或方形。
在一些方案中，所述导向弹簧由镍钛合金丝绕制而成；
所述导向弹簧的远端设置有球帽结构。
在一些方案中，所述收集网篮的近端设有第一显影标记；
所述可调控网球的近端设有第二显影标记；
所述可调控网球的远端设有第三显影标记。
在一些方案中，所述可调控网球为单个或多个网球串联。
本公开实施例提供了一种组合式调控取栓装置，通过控制单元的调节按钮调节输送单元的控制芯丝，实现可调控网球在穿过血栓后膨胀打开，然后继续通过调节按钮进行调节，将可调控网球及捕获的血栓回撤至收集网篮中并一起撤出体外。通过分段式的取栓装置，无需匹配血栓的长度，同时减少了对血管的刺激，防止在回撤时出现二次血栓的现象。
附图说明
图1为本公开实施例提供的一种组合式调控取栓装置的结构示意图；
图2为本公开实施例提供的收集网篮和可调控网球在压缩状态下的示意图；
图3为本公开实施例提供的收集网篮和可调控网球在展开状态下的示意图；
图4为本公开实施例提供的可调控网球与收集网篮相对位置的示意图；
图5为本公开实施例提供的可调控网球完全回收时的示意图；
图6为本公开实施例提供的双层收集网篮的断面结构示意图；
图7为本公开实施例提供的单层收集网篮的断面结构示意图；
图8为本公开实施例提供的收集网篮的编织结构的网孔密度示意图；
图9为本公开实施例提供的收集网篮和可调控网球的金属丝的编织路径平面结构路径示意图；
图10为本公开实施例提供的可调控网球的结构示意图之一；
图11为本公开实施例提供的可调控网球的结构示意图之二；
图12为本公开实施例提供的可调控网球的结构示意图之三；
图13为本公开实施例提供的可调控网球的结构示意图之四；
图14为本公开实施例提供的可调控网球的结构示意图之五；
图15a为本公开实施例提供的可调控网球的结构示意图之六；
图15b为本公开实施例提供的可调控网球的结构示意图之六的打开状 态示意图；
图16a为本公开实施例提供的一种组合式调控取栓装置的工作示意图之一；
图16b为本公开实施例提供的一种组合式调控取栓装置的工作示意图之二；
图16c为本公开实施例提供的一种组合式调控取栓装置的工作示意图之三；
图16d为本公开实施例提供的一种组合式调控取栓装置的工作示意图之四；
图16e为本公开实施例提供的一种组合式调控取栓装置的工作示意图之五。
具体实施方式
下面通过附图和实施例，对本公开的技术方案做进一步的详细描述。
本公开实施例提供了一种组合式调控取栓装置，包括控制单元、输送单元、收集网篮和可调控网球；输送单元包括外管、内管、控制芯丝和导向弹簧；内管可在外管中滑动，控制芯丝在内管中滑动，收集网篮的近端与外管的远端固定连接，可调控网球的近端与内管的远端固定连接；控制单元包括调节按钮，通过调节按钮调节内管实现可调控网球的位置调节，通过调节按钮调节控制芯丝实现可调控网球的状态调节；通过可调控网球的膨胀实现对血栓的捕获并将血栓回撤至收集网篮中并一起撤出体外。通过分段式的取栓装置，无需匹配血栓的长度，同时减少了对血管的刺激，防止在回撤时出现二次血栓的现象。
如本公开所讨论的，术语“远端”或“近端”用于下文有关相对于治疗医生或医学介入医生手持端的位置或方向的描述。“远端”是远离医师或介入医生手持端方向的位置。“近端”是靠近医生或介入医生手持端的 方向的位置。下面通过具体实施例对本公开进行详细说明，但应理解的是，以下实施例并非用于限制本公开，本领域技术人员能够想到将实施例中具体特征进行排列组合，形成基于本公开构思的其他类似方案。
如本公开所讨论的，术语“连接”可以是两者以直接方式连接，也可以是通过中间物实现间接连接，两种方式均应理解为“连接”所包含的内容。
图1为本公开实施例提供的一种组合式调控取栓装置的结构示意图；图2为本公开实施例提供的收集网篮和可调控网球在压缩状态下的示意图；图3为本公开实施例提供的收集网篮和可调控网球在展开状态下的示意图。如图1-3所示，组合式调控取栓装置包括：控制单元1、输送单元2、收集网篮3和可调控网球4。
控制单元1包括外壳11和滑动机构(图中未示出)，在外壳11上设置有调节按钮12，其中，调节按钮12包括第一调节按钮和第二调节按钮，同时，在外壳11上还设置有尺度标记13，尺度标记13用于显示调节按钮12的位置信息。
输送单元2包括外管21、内管22、控制芯丝23和导向弹簧24，其中，内管22穿设在外管21内，内管22的近端通过滑动机构与调节按钮12相连接，内管22可在外管21中滑动，调节按钮12通过滑动机构实现对内管22的调节，使内管22能够在外管21中滑动；控制芯丝23穿设在内管22中，控制芯丝23的近端通过滑动机构与调节按钮12相连接，控制芯丝23可在内管22中滑动，调节按钮12通过滑动结构实现对控制芯丝23的调节，使控制芯丝23能够在内管22中滑动。
收集网篮3的远端具有第一开口，收集网篮3的近端设置有第一显影标记31，收集网篮3的近端与外管21的远端固定连接，使得收集网篮3能够在外管21的作用下在血管内移动至相应的位置。
可调控网球4的近端设置有第二显影标记41，可调控网球4的近端与内 管22的远端固定连接，其固定连接方式可以为铆压或粘接的方式，可调控网球4的远端设置有第三显影标记42，可调控网球4的远端与导向弹簧24的近端相连接。控制芯丝23穿设在可调控网球4内，并且控制芯丝23的远端与第三显影标记42的远端以及导向弹簧24的近端固定连接，使得控制芯丝23在进行滑动时实现可调控网球4的膨胀或收缩。
滑动机构是一个运动转化机构，滑动机构可以为直连结构、螺旋结构、齿轮齿条结构、棘轮机构或连杆机构，滑动机构能够实现将对调节按钮12的调节转换为内管22或控制芯丝23的移动，进而实现对可调控网球4的位置及状态的调节。调节按钮12的调节方式可以为滑动、转动或拨动。
具体的，调节按钮12包括第一调节按钮和第二调节按钮，其中，第一调节按钮通过滑动机构与内管22的近端相连接，通过滑动机构对内管22的调节实现对收集网篮3在血管内位置的调节；第二调节按钮通过滑动机构与控制芯丝23的近端相连接，通过滑动机构对控制芯丝23的调节实现对可调控网球4的状态进行操控，实现可调控网球4的膨胀或收缩。
图4为本公开实施例提供的可调控网球与收集网篮相对位置的示意图，如图4所示，图中展示了可调控网球4相对于收集网篮3的能够活动伸缩的范围，通过调节可调控网球4相对于收集网篮3的位置，使组合式调控取栓装置能够适应不同长度的血栓，实现对不同长度血栓的抓取。
收集网篮3可以为单层网篮或多层网篮，收集网篮3在输送时处于压缩状态，从导管中推出时能够自动膨胀打开。收集网篮3由金属丝33交叉编织而成，在压缩状态下呈圆柱形。收集网篮3的远端的编织结构较密，近端的编织结构较稀疏，收集网篮3近端处的网眼的孔径大于收集网篮3远端处的网眼的孔径。当收集网篮3采用单层网篮时，在第一开口处设置有回口结构32，减少金属丝对血管的刺激，当收集网篮3采用多层网篮时，可采用U型环绕结构，避免网篮开口处对血管内壁造成刺激。
可调控网球4由金属丝33交叉编织而成，在压缩状态下呈圆柱形，在通 过调节按钮12调节下能够实现可调控网球4膨胀为球形、椭球形、盘形、锥形、圆柱形或香肠形。可调控网球4可以是单个网球，也可以由多个网球串联而成。
导向弹簧24是一种镍钛合金丝绕制而成的弹簧结构的柔软段，在导向弹簧24的远端设置有柔软的球帽结构241。
本公开实施例提供的第一显影标记31、第二显影标记41和第三显影标记42均为不透X射线标记，在工作时，能够通过显影标记观察收集网篮3和可调控网球4所处的位置，同时，编织收集网篮3和可调控网球4的金属丝亦采用显影丝，能够在X光下观察收集网篮3和可调控网球4的工作状态。
图5为本公开实施例提供的可调控网球完全回收时的示意图，如图5所示，可调控网球4在回收进入收集网篮3内时，可通过第二显影标记41和第三显影标记42进行观察，能够观察出可调控网球4在收集网篮3中的具体位置，能够轻松地实现在捕获血栓后对装置的回收。
图6为本公开实施例提供的双层收集网篮的断面结构示意图，如图6所示，双层结构地收集网篮3，其远端采用圆弧状设计，能够降低收集网篮3的远端对于血管内壁的刺激，能够更好的保护血管。
图7为本公开实施例提供的单层收集网篮的断面结构示意图，如图7所示，单层结构的收集网篮3，其远端采用密网孔U型结构，能够降低收集网篮3的远端对于血管内壁的刺激，能够更好的保护血管，同时，单层结构的收集网篮3的尺寸较小，能够降低整体输送单元2的结构尺寸，更有利于在更狭小的血管内使用。远端的U型结构具有显影作用，有利于观察收集网篮3的远端位置。
图8为本公开实施例提供的收集网篮的编织结构的网孔密度示意图，如图8所示，收集网篮3的近端网孔较稀疏，远端网孔较密，近端的较稀疏网孔有利于血栓通过，以便让负压抽吸装置将血栓吸出，较稀疏的网孔能够减少对血栓的切割，减少血栓破裂的风险；远端的较密网孔能够防止 血栓逃逸。
图9为本公开实施例提供的收集网篮和可调控网球的金属丝的编织路径平面结构路径示意图；收集网篮3和可调控网球4均是由金属丝33编织而成，其中，金属丝33可以为镍钛金属丝或钴铬合金丝。镍钛金属丝的截面可以为圆形、椭圆形或方形。金属丝33的编织方式采用交叉编织方式，如图9所示，图9中使用了一种2压2的交叉编织方式，即采用每两根金属丝33进行交叉编织的方式，也可以采用1压1或3压3的交叉编织方式，不同数量的金属丝的交叉编织所得到的收集网篮3，其网孔结构及径向力不同，技术人员可根据实际需要进行调整。
图10为本公开实施例提供的可调控网球的结构示意图之一；如图10所示，可调控网球4为鸭梨型结构，该结构更有利于嵌入血栓，与血栓的接触面积更大，更有利于血栓从血管壁脱离；同时，该结构近端较小，在血栓回收时更有利于进入收集网篮3。
图11为本公开实施例提供的可调控网球的结构示意图之二，如图11所示，该结构的可调控网球4包括近端的小球结构和远端的大球结构，小球结构更有利于嵌入血栓并起到固定血栓的作用，远端的大球结构能够更好地防止血栓逃离。
图12为本公开实施例提供的可调控网球的结构示意图之三，如图12所示，可调控网球4的截面呈双侧鱼钩型截面，该结构的可调控网球4在收集血栓时，能够与血栓之间形成嵌入结构，鱼钩结构能够更好地将血管内壁的血栓剥离，同时也能够将血栓碎屑进行回收，防止碎小的血栓逃离。
图13为本公开实施例提供的可调控网球的结构示意图之四，如图13所示，该结构的可调控网球4能够更好地适应血管，降低可调控网球4与血管之间的内摩擦力，将血栓有效地脱离血管并拉动到收集网篮3内。
图14为本公开实施例提供的可调控网球的结构示意图之五，如图14所示，该结构的可调控网球4为一种手提篮式的结构，近端具有开口，远 端为密网结构，膨胀后能够与血管内壁贴合，将血栓与可调控网球4形成一个整体，使血栓与可调控网球4之间形成一个套索式的滑动装置，更加有利于血栓与血管之间的剥离，能够有效地降低可调控网球4对血管内壁的刺激。
图15a为本公开实施例提供的可调控网球的结构示意图之六；图15b为本公开实施例提供的可调控网球的结构示意图之六的打开状态示意图，如图15a和15b所示，该结构中结合弹簧式铰链机构，使可调控网球4在打开后形成凹陷型网盘结构，使可调控网球4与铰链机构形成相应的血栓收集可调网球，多铰链机构的优势是能够通过铰链的连接点有限的控制可调控网球4的结构形态变化。
本公开实施例提供的一种组合式调控取栓装置中，外管21的外径为0.3～2mm，内径为0.2～1.8mm；内管22的外径为0.2～1.6mm，内径为0.1～1.4mm；控制芯丝23的直径为0.08～1mm；收集网篮3的外径为1～10mm；收集网篮3的编织金属丝的直径为0.01～0.16mm；可调控网球4的外径为0.6～10mm；可调控网球4的编织金属丝的直径为0.01～0.16mm。
本公开实施例提供的一种组合式调控取栓装置的具体工作过程按如下方式进行：
通过旋转或推拉操作调节按钮12拉动控制芯丝23，控制芯丝23拉紧可调控网球4，实现可调控网球4膨胀打开，然后通过调节按钮12控制内管实现可调控网球4的回撤，将捕获的血栓收集至收集网篮3内并一起回撤至导管内，然后整体一起撤出体外，实现对血管内的血栓的取出操作。
具体的，图16a-图16e为本公开实施例提供的一种组合式调控取栓装置的工作示意图，如图16a-图16e所示，在图16a中，导管7是一种常见的介入治疗中使用的输送导管，通过导管7将取栓装置输送至血管5中的血栓6处，通过观察显影标记，当导管7的远端穿过血栓6后，通过调节按钮12调节内管22将可调控网球4推出导管7。
在图16b中，通过调节按钮12调节控制芯丝23实现可调控网球4在原位置膨胀。同时，对导管7进行回撤。
在图16c中，导管7回撤至血栓6的近端，但此时收集网篮3还位于导管7内，处于未打开状态。
在图16d中，继续回撤导管7至收集网篮3的近端，使收集网篮3完全暴露在血管5内，此时，收集网篮3自动打开，与可调控网球4一起对血栓6进行捕获。
在图16e中，通过调节按钮12调节内管22，使其带动可调控网球4进行回撤，将捕获的血栓6收集到收集网篮3内，并随收集网篮3一起撤出体外。
本公开实施例提供了一种组合式调控取栓装置，通过控制单元的调节按钮调节输送单元的内管和控制芯丝，实现可调控网球在穿过血栓后膨胀打开，然后继续通过调节按钮进行调节，将可调控网球及捕获的血栓回撤至收集网篮中并一起撤出体外。通过分段式的取栓装置，无需匹配血栓的长度，同时减少了对血管的刺激，防止在回撤时出现二次血栓的现象
以上所述的具体实施方式，对本公开的目的、技术方案和有益效果进行了进一步详细说明，所应理解的是，以上所述仅为本公开的具体实施方式而已，并不用于限定本公开的保护范围，凡在本公开的精神和原则之内，所做的任何修改、等同替换、改进等，均应包含在本公开的保护范围之内。

Claims (13)

  1. 一种组合式调控取栓装置，其特征在于，所述装置包括：
    控制单元；
    输送单元，所述输送单元包括外管、内管、控制芯丝和导向弹簧；所述内管穿设在所述外管内，所述内管的近端与所述控制单元相连接，所述内管配置为在所述控制单元的调节下实现在所述外管内滑动；所述控制芯丝穿设在所述内管内，所述控制芯丝的近端与所述控制单元相连接，所述控制芯丝配置为在所述控制单元的调节下实现在所述内管内滑动；
    收集网篮，所述收集网篮的近端与所述外管的远端固定连接；
    可调控网球，所述可调控网球的近端与所述内管的远端固定连接，所述可调控网球的远端与所述导向弹簧的近端相连接；所述控制芯丝穿设在所述可调控网球内，并且所述控制芯丝的远端与所述导向弹簧的近端固定连接，以使所述可调控网球在所述控制芯丝的作用下实现膨胀或收缩。
  2. 根据权利要求1所述的组合式调控取栓装置，其特征在于，所述控制单元包括外壳和滑动机构；
    所述外壳上设置有调节按钮。
  3. 根据权利要求2所述的组合式调控取栓装置，其特征在于，所述外壳上设置有尺度标记，所述尺度标记用于显示所述调节按钮的位置信息。
  4. 根据权利要求2所述的组合式调控取栓装置，其特征在于，所述滑动机构为直连机构、螺旋机构、齿轮齿条机构、棘轮机构或连杆机构。
  5. 根据权利要求2所述的组合式调控取栓装置，其特征在于，所述调节按钮的调节方式包括滑动、转动或拨动。
  6. 根据权利要求2所述的组合式调控取栓装置，其特征在于，所述调节按钮包括第一调节按钮和第二调节按钮；
    所述第一调节按钮通过所述滑动机构与所述内管的近端相连接，用于调节所述可调控网球与所述收集网篮之间的相对位置；
    所述第二调节按钮通过所述滑动机构与所述控制芯丝的近端相连接，用于调节所述可调控网球的膨胀或收缩。
  7. 根据权利要求1所述的组合式调控取栓装置，其特征在于，所述收集网篮为单层网篮或多层网篮；
    所述收集网篮近端处的网眼的孔径大于所述收集网篮远端处的网眼的孔径。
  8. 根据权利要求1所述的组合式调控取栓装置，其特征在于，所述收集网篮由镍钛金属丝或钴铬合金丝交叉编织而成；
    所述收集网篮在压缩状态下呈圆柱形。
  9. 根据权利要求1所述的组合式调控取栓装置，其特征在于，所述可调控网球由镍钛金属丝或钴铬合金丝交叉编织而成；
    所述可调控网球在压缩状态下呈圆柱形；
    所述可调控网球在膨胀状态下呈球形、椭球形、盘形、锥形、圆柱形或香肠形。
  10. 根据权利要求9所述的组合式调控取栓装置，其特征在于，所述镍钛金属丝的截面为圆形、椭圆形或方形。
  11. 根据权利要求1所述的组合式调控取栓装置，其特征在于，所述导向弹簧由镍钛合金丝绕制而成；
    所述导向弹簧的远端设置有球帽结构。
  12. 根据权利要求1所述的组合式调控取栓装置，其特征在于，所述收集网篮的近端设有第一显影标记；
    所述可调控网球的近端设有第二显影标记；
    所述可调控网球的远端设有第三显影标记。
  13. 根据权利要求1所述的组合式调控取栓装置，其特征在于，所述可调控网球为单个或多个网球串联。
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