WO2022247695A1 - 一种用于改善血管内皮功能的便携式装置 - Google Patents

一种用于改善血管内皮功能的便携式装置 Download PDF

Info

Publication number
WO2022247695A1
WO2022247695A1 PCT/CN2022/093469 CN2022093469W WO2022247695A1 WO 2022247695 A1 WO2022247695 A1 WO 2022247695A1 CN 2022093469 W CN2022093469 W CN 2022093469W WO 2022247695 A1 WO2022247695 A1 WO 2022247695A1
Authority
WO
WIPO (PCT)
Prior art keywords
time
pulse wave
controller
preset
pressure
Prior art date
Application number
PCT/CN2022/093469
Other languages
English (en)
French (fr)
Inventor
张焰
马骥
郑振声
张新奇
Original Assignee
中山大学附属第一医院
佛山市华文医疗仪器有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 中山大学附属第一医院, 佛山市华文医疗仪器有限公司 filed Critical 中山大学附属第一医院
Publication of WO2022247695A1 publication Critical patent/WO2022247695A1/zh

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H9/00—Pneumatic or hydraulic massage
    • A61H9/005—Pneumatic massage
    • A61H9/0078—Pneumatic massage with intermittent or alternately inflated bladders or cuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2205/00—Devices for specific parts of the body
    • A61H2205/10—Leg
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2230/00—Measuring physical parameters of the user
    • A61H2230/04—Heartbeat characteristics, e.g. E.G.C., blood pressure modulation
    • A61H2230/06—Heartbeat rate
    • A61H2230/065—Heartbeat rate used as a control parameter for the apparatus

Definitions

  • the invention relates to the field of medical devices, in particular to a portable device for improving vascular endothelial function.
  • the vascular endothelium is an important physiological part of the human body.
  • the function of the vascular endothelium has an important impact on the cardiovascular system and even the whole body. process.
  • a large amount of evidence-based medical evidence has confirmed that improving vascular endothelial function has the effect of anti-atherosclerosis, prevention and treatment of cardiovascular and cerebrovascular diseases.
  • current measures to improve vascular endothelial function include moderately increasing the shear stress of blood flow.
  • the methods that can be used in the human body to actively increase the shear stress of blood flow mainly include exercise and external counterpulsation.
  • the external anti-thrombotic equipment used in existing hospitals is too large to be easily moved and carried, which leads to the need for patients to go to the hospital repeatedly for treatment, which is not convenient enough.
  • Embodiments of the present invention provide a portable device for improving vascular endothelial function, which is convenient for patients to carry, enables patients to choose a treatment location independently, and improves convenience.
  • An embodiment of the present invention provides a portable device for improving the function of the vascular endothelium, including: a trolley box-type air distribution host, a control terminal, a capsule, a pulse wave sensor, and an external airway;
  • the trolley box-type gas distribution host includes: a box body, a pulley, a trolley, an air guide hole, a pulse wave sensor interface, a control terminal interface, a controller, an air source, a constant current voltage stabilizing device, an inflation control device, and an exhaust control device;
  • the controller, the air source, the constant current and voltage stabilizing device, the inflation control device and the exhaust control device are all arranged in the box;
  • the gas source communicates with the constant current and voltage stabilizing device, the constant current and voltage stabilizing device communicates with the inflation control device and the exhaust control device, and the inflation control device and the exhaust control device communicate with the exhaust gas control device.
  • the air guide hole is communicated; one end of the external air guide tube is communicated with the air guide hole, and the other end of the external air guide tube is communicated with the bag sleeve;
  • the controller is connected with the gas source, the constant current and voltage stabilizing device, the inflation control device and the exhaust control device;
  • the control terminal is connected to the controller through the control terminal interface, and the pulse wave sensor is communicated with the controller through the pulse wave sensor interface;
  • the pulse wave sensor is used to collect the pulse wave signal of the patient and transmit the pulse wave signal to the controller, so that the controller transmits the pulse wave signal to the control terminal;
  • the control terminal is used to determine the corresponding target pressure application time and target pressure release time in the treatment process according to the pulse wave signal, and generate a final driving signal according to the target pressure application time and target pressure release time;
  • the controller is used to control the working states of the gas source, the constant current and voltage stabilizing device, the inflation control device and the exhaust control device according to the final drive signal during the treatment process, and control the
  • the bladder is inflated or deflated.
  • control terminal is used to determine the corresponding target pressure application time and target pressure release time during the treatment process according to the pulse wave signal, specifically including:
  • the pulse wave waveform data of the several cycles calculate the average time from the starting point of the pulse wave to the crest point of the main wave in several cycles, and obtain the first target time; the preset pressure-building duration range after the first target time In , select a time point as the average pressure time;
  • the average pressing time is moved forward by the first preset time interval for the first preset number of times, and the time after each forward shift is recorded, and the average pressing time is moved backward by the second preset time interval.
  • the time is moved forward by the first preset number of times according to the first preset time interval, and the time after each advance is recorded, and the average pressure release time is moved backward by the second preset number of times according to the first preset time interval, and recorded
  • the time after each backward movement is based on the average pressure release time, the time after each forward movement and the time after each backward movement, to generate a time series of pressure relief;
  • a pressure application time is sequentially extracted from the pressure application time series, and a pressure release time is extracted from the pressure release time series.
  • a pressure release time is extracted from the pressure release time series.
  • the pulse wave characteristic value includes: the peak value of the main pulse wave wave or the area of the main pulse wave wave.
  • control terminal is also used to monitor the patient's pulse wave characteristic value in real time during the treatment process, and if the pulse wave characteristic value is lower than a preset threshold value, the target pressure application time and the The above target decompression time is updated.
  • control terminal is further configured to update the target pressure application time and the target pressure release time when a preset update period arrives.
  • control terminal is also used to monitor the air pressure of the bag, and if the air pressure of the bag exceeds a preset pressure threshold, send an exhaust instruction to the controller, so that the After receiving the deflation instruction, the controller controls the cuff to deflate.
  • the box is also provided with a storage cavity.
  • the implementation of the present invention provides a portable device for improving the function of the vascular endothelium.
  • the device includes a trolley box-type gas distribution host, a control terminal, a bag, a pulse wave sensor, and an external air guide tube;
  • the trolley box-type gas distribution host is equipped with Controller, air source, constant current and voltage stabilizing device, inflation control device and exhaust control device;
  • the pulse wave sensor collects the patient's pulse wave signal and then transmits it to the control terminal, and the control terminal generates the final drive signal in the treatment process according to the pulse wave signal , sent to the controller of the trolley box-type gas distribution host;
  • the controller controls the working status of the gas source, constant current and voltage stabilizing device, inflation control device and exhaust control device according to the final drive signal, and then completes inflation or exhaust.
  • the present invention adopts a trolley box-type gas distribution main unit for air supply, and the trolley box-type gas distribution main unit can be moved arbitrarily and is easy to carry around. Patients do not need to be fixed in the hospital for treatment, but can be treated at the place they choose, which improves the convenience.
  • Fig. 1 is a schematic structural diagram of a portable device for improving vascular endothelial function provided by an embodiment of the present invention.
  • Fig. 2 is a perspective view of the internal structure of the trolley box air distribution main unit provided by an embodiment of the present invention.
  • FIG. 3 is a schematic structural diagram of a constant current voltage stabilizing device provided by an embodiment of the present invention.
  • control terminal 1 control terminal 1
  • pulse wave sensor 2 trolley box-type gas distribution host 3
  • external airway 4 bag cover 5
  • box body 301 pulley 302
  • control terminal interface 303 pulse wave sensor interface 304
  • pull rod 305 air guiding hole 306
  • internal air guiding pipe 307 inflation control device 308
  • exhaust control device 309 controller 310
  • gas source 311 constant current and voltage stabilizing device 312
  • gas outlet 313, gas inlet 314, gas storage chamber 315, Piston 316 and spring 317 control terminal 1
  • an embodiment of the present invention provides a portable device for improving the function of the vascular endothelium, including: a trolley box-type air distribution host 3, a control terminal 1 (preferably a notebook computer), a pocket 5. Pulse wave sensor 2 and external airway tube 4;
  • the trolley box-type gas distribution main engine 3 includes: a box body 301, a pulley 302, a trolley 305 (a retractable trolley), an air guide hole 306, a pulse wave sensor interface 304, a control terminal interface 303, a controller 310, an air source 311, a constant current The voltage stabilizing device 312 and the adjustable gas distribution device; the controller 310, the gas source 311, the constant current voltage stabilizing device 312, the inflation control device 308 and the exhaust control device 309 are all arranged in the box body 301;
  • the gas source 311 is connected to the constant current and voltage stabilizing device 312, and the constant current and voltage stabilizing device 312 communicates with the inflation control device 308 and the exhaust control device 309 through the internal air duct 307;
  • the air guide tube 307 communicates with the air guide hole 306 .
  • One end of the external air guide tube 4 communicates with the air guide hole 306, and the other end of the external air guide tube 4 communicates with the bag cover 5;
  • the controller 310 communicates with the above-mentioned air source 311, constant current and voltage stabilizing device 312, inflation control device 308 and exhaust control device 309 connection.
  • the control terminal 1 is connected to the controller 310 through the control terminal interface 303, and the pulse wave sensor 2 is connected to the controller 310 through the pulse wave sensor interface 304;
  • the pulse wave sensor 2 is used to collect the pulse wave signal of the patient and transmit the pulse wave signal to the controller 310, so that the controller 310 transmits the pulse wave signal to the control terminal 1;
  • the control terminal 1 is used to determine the corresponding target pressure application time and target pressure release time during the treatment process according to the pulse wave signal, and generate the final driving signal according to the target pressure application time and target pressure release time;
  • the controller 310 is used to control the working states of the air source 311, the constant current and voltage regulator device 312, the inflation control device 308 and the exhaust control device 309 according to the final driving signal during the treatment process, and inflate or exhaust the cuff 5.
  • the pulse wave sensor 2 collects the patient's pulse wave signal and then transmits it to the control terminal 1, and the control terminal 1 generates the final drive signal in the treatment process according to the pulse wave signal, and then The final driving signal is sent to the controller 310 of the trolley box type gas distribution host 3 .
  • the final drive signal includes the target pressure application time and target pressure release time during treatment; the controller 310 receives the final drive signal and starts to treat the patient.
  • the controller 310 controls The gas source 311 is turned on, the inflation control device 308 is controlled to be turned on, the gas outlet 313 and the air inlet 314 of the constant current and voltage stabilizing device 312 are controlled to be turned on, and the exhaust control device 309 is controlled to be turned off.
  • the gas source 311 starts to inflate the constant current and voltage stabilizing device 312, and the gas in the constant current and voltage stabilizing device flows into the bag cover 5, and the bag cover 5 is inflated with a certain pressure, so that the bag cover 5 is inflated to the patient's lower limbs and buttocks. Apply pressure so that blood from the lower extremities and buttocks flows back toward the head.
  • the controller 310 controls the gas source 311 to close, controls the inflation control device 308 to close, controls the exhaust control device 309 to open, and controls the gas outlet 313 and the air inlet 314 of the constant flow regulator device 312 to close .
  • the gas in the bag cover 5 is discharged through the exhaust control device.
  • the blood vessels of the compressed limbs are opened, the blood flow is accelerated along the physiological direction, the blood flow is increased, and the shear stress of the pulsating blood flow is increased, thereby improving the function of the vascular endothelium.
  • the controller 310 repeatedly controls the cuff 5 to inflate and deflate according to the target pressure application time and target pressure application time set in the final drive signal, until the entire treatment process ends.
  • the above-mentioned gas source 311 is a low-pressure, high-flow oil-free air pump
  • the above-mentioned inflation control device 308 is an inflation valve
  • the above-mentioned exhaust control device 309 is an exhaust valve
  • the constant current voltage stabilizing device 312 includes an air outlet 313, an air inlet 314, an air storage chamber 315, a piston 316 and a spring 317; the piston 316 is connected to the spring 317;
  • the above-mentioned inflation control device 308 and the exhaust control device 309 are in communication;
  • the air inlet 314 is in communication with the above-mentioned gas source 311;
  • the gas in the gas storage chamber 315 flows into the bag cover through the gas outlet 313, the gas pressure in the gas storage chamber drops, the piston 316 moves outward under the action of the spring 317, the space of the gas storage chamber 315 becomes smaller, and the gas pressure rise to realize the voltage regulation function.
  • the above-mentioned embodiment of the present invention adopts the trolley box-type gas distribution host for gas supply, and the trolley box-type gas distribution host can be moved arbitrarily and is easy to carry. Patients do not need to be fixed in the hospital for treatment, but can be treated in a place of their own choice, which improves convenience.
  • the gas distribution system is driven by the control terminal through the pulse wave signal instead of the electrocardiogram signal, which is more convenient for patients to use by themselves.
  • the pulse wave signals of different people are also different. Therefore, it is necessary to go through the stages of observation, trial, rough adjustment, fine adjustment, monitoring, and update to determine the best pressure time and best release time for each person. Improve healing effect.
  • control terminal 1 is used to determine the corresponding target pressure application time and target pressure release time during the treatment process according to the pulse wave signal, specifically including:
  • the pulse wave waveform data of the several cycles calculate the average time from the starting point of the pulse wave to the crest point of the main wave in several cycles, and obtain the first target time; the preset pressure-building duration range after the first target time In , select a time point as the average pressure time;
  • the average pressing time is moved forward by the first preset time interval for the first preset number of times, and the time after each forward shift is recorded, and the average pressing time is moved backward by the second preset time interval.
  • the time is moved forward by the first preset number of times according to the first preset time interval, and the time after each advance is recorded, and the average pressure release time is moved backward by the second preset number of times according to the first preset time interval, and recorded
  • the time after each backward movement is based on the average pressure release time, the time after each forward movement and the time after each backward movement, to generate a time series of pressure relief;
  • a pressure application time is successively extracted from the pressure application time series, and a pressure release time is extracted from the pressure release time series.
  • the pulse wave characteristic value includes: the peak value of the main pulse wave or the area of the main pulse wave.
  • N (preferably 10) cycles of pulse waveform data are obtained, and then the peak point of the pulse wave main wave is identified with the maximum value point, and the peak point of the pulse wave main wave is identified with the minimum value point as The trough point of the pulse wave, and then calculate the duration from the pulse wave start point to the main wave peak point in each cycle, and the duration from the pulse wave start point to the pulse wave trough point in each cycle, and then calculate the N cycle pulse wave start point
  • the average duration of the duration from the starting point to the peak point of the main wave is used to obtain an average duration, and this average duration is used as the above-mentioned first target time; then, within the preset pressure-building duration range after the first target time, select the preset A time point in the pressure duration range is used as the average pressure time; generally speaking, 50ms-150ms after the peak point of the main wave is the beginning of the diastolic period, and the peripheral blood begins to flow back, so it needs to be 50
  • the above-mentioned preset compression time range is set to 50ms-150ms (including 50ms and 150ms), and then the first target time is selected and preset A time point within the pressure application time range is, for example, 100 ms, that is, 100 ms after the above-mentioned first target time is used as the average pressure application time.
  • the normal value of the time from the starting point of the pulse wave to the peak point of the main wave is between 70ms-110ms, and the subsequent 50ms-150ms is the time when the aortic valve closes and the diastolic period begins, so the time point of the starting point of the pulse wave Initially, the above-mentioned average pressure time should be between 120ms-260ms; now assume that the average time from the starting point of the above-mentioned pulse wave to the peak point of the main wave is 100ms, that is, the above-mentioned first target time is 100ms, and the average pressure time is the above-mentioned first 100ms after the target time is 200ms.
  • the above-mentioned average pressing time is moved forward by the first preset time interval (for example, 1 time) according to the first preset time interval, such as 50 ms, and moved backward by the second preset number of times (for example, 1 time), and then you can get A stress time series (150ms, 200ms, 250ms).
  • first preset time interval for example, 1 time
  • second preset number of times for example, 1 time
  • the normal value of the time from the pulse wave starting point to the pulse wave trough point is between 480ms-1000ms.
  • the above-mentioned average pressure release time is 750ms.
  • the above-mentioned average pressure release time is moved forward by the first preset number of times (for example, 1 time) according to the first preset time interval, and moved backward by the second preset number of times (for example, 1 time), and then a pressure release time series is obtained (700ms, 750ms, 800ms), each time in the pressure time series and release time series corresponds to each other in chronological order.
  • a pressure application time and a pressure release time are successively extracted from the pressure application time series and the pressure release time series in chronological order, for example, the first time the pressure application time is extracted: 150ms, and the pressure release time is 700ms, and then a Compression time: drive signal of 150ms and release time of 700ms, the drive signal is sent to the controller 310, and the controller 310 controls the inflation of the bag cover 5 (at this time, the bag cover 5 is still worn on the patient's lower limbs and buttocks) according to the drive signal and exhaust, complete a test cycle, and then calculate and record the pulse wave characteristic value corresponding to the test cycle.
  • the second extraction is carried out, and the pressure application time is extracted: 200ms, and the pressure release time is 750ms, and then the above process is repeated to complete the second test cycle. And so on, until the time in the pressure time series and the pressure release time series are all extracted.
  • compare the pulse wave eigenvalues of the pulse waves in all test cycles use the pressure application time and pressure release time corresponding to the test cycle with the largest pulse wave eigenvalue as the above-mentioned target pressure application time and target pressure release time of the present invention.
  • the final driving signal is generated according to the target pressure application time and target pressure release time, and the bag cuff 5 is pressurized and released.
  • the above-mentioned adjustment is a stage of coarse adjustment.
  • more fine adjustments can be made to the above-mentioned target pressure application time and the above-mentioned target pressure release time.
  • the target pressure application time and target pressure release time are completed to obtain the target pressure application time and target pressure release time.
  • the specific method is similar to the above-mentioned adjustment steps, the difference is that during the second adjustment, the above-mentioned average pressure application time is replaced by the above-mentioned target pressure application time, the above-mentioned average pressure release time is replaced by the target pressure release time, and the above-mentioned first preset time The interval is replaced by the second preset time interval (for example, 25ms).
  • the second preset time interval for example, 25ms.
  • control terminal 1 is also used for real-time monitoring of the patient's pulse wave characteristic value during treatment, and if the pulse wave characteristic value is lower than the preset threshold value, the target pressure time and target The release time is updated.
  • the control terminal 1 through real-time monitoring of the pulse wave characteristic value, once the pulse wave characteristic value is lower than the preset threshold, it means that the patient’s heart rate and pulse have undergone relatively large changes during the treatment process.
  • the compression time and the target pressure release time are no longer suitable. At this time, the target pressure application time and the target pressure release time are adjusted according to the above-mentioned secondary adjustment step of the present invention, thereby improving the therapeutic effect.
  • control terminal 1 is also used to update the target pressure application time and target pressure release time when a preset update period arrives.
  • the aforementioned preset update period may be (10 minutes).
  • the target pressure application time and target pressure release time are adjusted according to the preset cycle, so as to prevent the problem that the treatment effect is not good due to the physiological changes of the patient during the long-term treatment process.
  • adjustments can be made according to the above-mentioned secondary adjustment steps of the present invention.
  • control terminal 1 is also used to monitor the air pressure of the cuff 5, and if the air pressure of the cuff 5 exceeds a preset pressure threshold, an exhaust instruction is sent to the controller 312, so that the control The controller 310 controls the bag 5 to be deflated after receiving the deflate instruction.
  • the above-mentioned external airway is a detachable airway, which can be removed when not in use.
  • the box body 301 is also provided with a storage cavity.
  • the storage cavity on the box body 301 can be used to place the cuff 5 , the pulse wave sensor 2 and the external airway tube 4 . In this way, the user only needs to drag the trolley box-type gas distribution main unit 3 to carry the whole portable device for improving the function of the vascular endothelium, which is more convenient.

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rehabilitation Therapy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

本发明公开了一种用于改善血管内皮功能的便携式装置，该装置包括拉杆箱式配气主机、控制终端、囊套、脉搏波传感器以及外部导气管；拉杆箱式配气主机内配置有控制器、恒流稳压装置、气源、充气控制装置以及排气控制装置；脉搏波传感器采集患者的脉搏波信号然后传输至控制终端，控制终端根据脉搏波信号确生成治疗过程中的最终驱动信号，发送至拉杆箱式配气主机的控制器；控制器根据最终驱动信号，控制恒流稳压装置、气源、充气控制装置以及排气控制装置的工作状态，进而完成充气或排气。通过实施本发明实施例所提供的用于改善血管内皮功能的便携式装置方便患者携带，使得患者能够自主选择治疗场所，提高了便捷性。

Description

一种用于改善血管内皮功能的便携式装置 技术领域
本发明涉及医疗器械领域，尤其涉及一种用于改善血管内皮功能的便携式装置。
背景技术
血管内皮是人体重要的生理组成部分，血管内皮功能对心血管系统乃至全身具有重要影响，血管内皮功能障碍是动脉粥样硬化病变形成的始动环节，并且贯穿于动脉粥样硬化发生发展的全过程。大量循证医学证据证实改善血管内皮功能具有抗动脉粥样硬化、预防和治疗心脑血管疾病的作用。目前能改善血管内皮功能的措施除了使用药物以外，还有适度提高血流剪切应力。目前能够运用在人体主动提高血流剪切应力的方法主要包括运动和体外反搏。但是并非所有患者都能达到充分的运动量，而现有医院使用的体外反博设备体积较大无法轻易移动和携带，这就导致了患者需要反复多次去医院进行治疗，不够便捷。
发明内容
本发明实施例提供一种用于改善血管内皮功能的便携式装置，方便患者携带，使得患者能够自主选择治疗场所，提高了便捷性。
本发明一实施例提供一种用于改善血管内皮功能的便携式装置，包括：拉杆箱式配气主机、控制终端、囊套、脉搏波传感器以及外部导气管；
所述拉杆箱式配气主机包括：箱体、滑轮、拉杆、导气孔、脉搏波传感器接口、控制终端接口、控制器、气源、恒流稳压装置、充气控制装置以及排气控制装置；所述控制器、所述气源、所述恒流稳压装置、充气控制装置以及排气控制 装置均设置在所述箱体内；
所述气源与所述恒流稳压装置连通，所述恒流稳压装置与所述充气控制装置以及所述排气控制装置连通，所述充气控制装置以及所述排气控制装置与所述导气孔连通；所述外部导气管的一端与所述导气孔连通，所述外部导气管的另一端与所述囊套连通；
所述控制器与所述气源、所述恒流稳压装置、所述充气控制装置以及所述排气控制装置连接；
所述控制终端通过所述控制终端接口与所述控制器连接，所述脉搏波传感器通过所述脉搏波传感器接口与所述控制器连通；
所述脉搏波传感器，用于采集患者的脉搏波信号并将所述脉搏波信号传输至所述控制器，以使所述控制器将所述脉搏波信号传输至所述控制终端；
所述控制终端，用于根据所述脉搏波信号确定治疗过程中所对应的目标施压时间和目标释压时间，并根据所述目标施压时间和目标释压时间生成最终驱动信号；
所述控制器，用于在治疗过程中根据所述最终驱动信号控制所述气源、所述恒流稳压装置、所述充气控制装置以及所述排气控制装置的工作状态，对所述囊套进行充气或排气。
进一步的，所述控制终端用于根据所述脉搏波信号确定治疗过程中所对应的目标施压时间和目标释压时间，具体包括：
根据所述脉搏波信号，提取若干周期的脉搏波波形数据；
根据所述若干周期的脉搏波波形数据，计算若干个周期中脉搏波起始点到主波波峰点的平均时间，获得第一目标时间；在所述第一目标时间后的预设施压时长范围内，选取一时间点作为平均施压时间；
计算若干个周期中脉搏波起始点到波谷点的平均时间，获得平均释压时间；
将所述平均施压时间按第一预设时间间隔前移第一预设次数，并记录每次前移后的时间，将所述平均施压时间按第一预设时间间隔后移第二预设次数，并记录每次后移后的时间，根据所述平均施压时间、每次前移后的时间以及每次后移后的时间，生成施压时间序列；将所述平均释压时间按第一预设时间间隔前移第一预设次数，并记录每次前移后的时间，将所述平均释压时间按第一预设时间间隔后移第二预设次数，并记录每次后移后的时间，根据所述平均释压时间、每次前移后的时间以及每次后移后的时间，生成释压时间序列；
根据时间先后顺序依次从所述施压时间序列提取出一施压时间，从所述释压时间序列中提取出一释压时间，在每次提取出施压时间和释压时间后，根据当次所提取的施压时间和释压时间生成驱动信号，并将驱动信号传输至控制器，以使所述控制器在接收驱动信号后，根据驱动信号内的施压时间对所述囊套进行充气，根据驱动信号内的释压时间对所述囊套进行排气；
计算所述控制器每一次根据驱动信号完成对所述囊套控制后的脉搏波特征值，并将脉搏波特征值最大时所对应的驱动信号的施压时间作为所述目标施压时间，将脉搏波特征值最大时所对应的驱动信号的释压时间作为所述目标释压时间；其中，所述脉搏波特征值包括：脉搏波主波峰值或脉搏波主波面积。
进一步的，所述控制终端还用于，在治疗过程中对患者的脉搏波特征值进行实时监测，若所述脉搏波特征值低于预设阈值时，则对所述目标施压时间和所述目标释压时间进行更新。
进一步的，所述控制终端还用于，在预设的更新周期到来时，对所述目标施压时间和所述目标释压时间进行更新。
进一步的，所述控制终端还用于，对所述囊套的气压进行监测，若所述囊套的气压超过预设压力阈值时，则向所述控制器发送排气指令，以使所述控制器在 接收所述排气指令后，控制所述囊套排气。
进一步的，所述箱体还设置收纳腔。
通过实施本发明实施例具有如下有益效果：
本发明实施提供了一种用于改善血管内皮功能的便携式装置，该装置包括拉杆箱式配气主机、控制终端、囊套、脉搏波传感器以及外部导气管；拉杆箱式配气主机内配置有控制器、气源、恒流稳压装置、充气控制装置以及排气控制装置；脉搏波传感器采集患者的脉搏波信号然后传输至控制终端，控制终端根据脉搏波信号生成治疗过程中的最终驱动信号，发送至拉杆箱式配气主机的控制器；控制器根据最终驱动信号，控制气源、恒流稳压装置、充气控制装置以及排气控制装置的工作状态，进而完成充气或排气。相比与现有技术，本发明采用拉杆箱式配气主机进行供气，拉杆箱式配气主机可任意移动，容易随身携带。患者不需要固定在医院中进行治疗，可以在自己选定的场所进行，提高了便捷性。
附图说明
图1是本发明一实施例提供的一种用于改善血管内皮功能的便携式装置的结构示意图。
图2是本发明一实施例提供的拉杆箱式配气主机的内部结构透视图。
图3是本发明一实施例提供的恒流稳压装置的结构示意图。
附图标记说明：控制终端1、脉搏波传感器2、拉杆箱式配气主机3、外部导气管4、囊套5、箱体301、滑轮302、控制终端接口303、脉搏波传感器接口304、拉杆305、导气孔306、内部导气管307、充气控制装置308、排气控制装置309、控制器310、气源311、恒流稳压装置312、出气口313、入气口314、储气室315、活塞316以及弹簧317。
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
同时参见图1和2,本发明一实施例提供了一种用于改善血管内皮功能的便携式装置,包括：拉杆箱式配气主机3、控制终端1(优选的可以为笔记本电脑)、囊套5、脉搏波传感器2以及外部导气管4；
拉杆箱式配气主机3包括：箱体301、滑轮302、拉杆305(可伸缩式拉杆)、导气孔306、脉搏波传感器接口304、控制终端接口303、控制器310、气源311、恒流稳压装置312、以及可调配气装置；控制器310、气源311、恒流稳压装置312、充气控制装置308以及排气控制装置309均设置在箱体301内；
气源311与恒流稳压装置312连接，恒流稳压装置312通过内部导气管307道与充气控制装置308以及排气控制装置309连通；充气控制装置308以及排气控制装置309均通过内部导气管307与导气孔306连通。外部导气管4的一端与导气孔306连通，外部导气管4的另一端与囊套5连通；控制器310与上述气源311、恒流稳压装置312、充气控制装置308以及排气控制装置309连接。
控制终端1通过控制终端接口303与控制器310连接，脉搏波传感器2通过脉搏波传感器接口304与控制器310连通；
脉搏波传感器2，用于采集患者的脉搏波信号并将脉搏波信号传输至控制器310，以使控制器310将脉搏波信号传输至控制终端1；
控制终端1，用于根据脉搏波信号确定治疗过程中所对应的目标施压时间和目标释压时间，并根据目标施压时间和目标释压时间生成最终驱动信号；
控制器310，用于在治疗过程中根据最终驱动信号控制气源311、恒流稳压装置312、充气控制装置308以及排气控制装置309的工作状态，对囊套5进行 充气或排气。
使用时，将囊套5佩戴在患者的下肢及臀部，脉搏波传感器2采集患者的脉搏波信号然后传输至控制终端1，控制终端1根据脉搏波信号生成治疗过程中的最终驱动信号，然后将最终驱动信号发送至拉杆箱式配气主机3的控制器310。该最终驱动信号中包含了在进行治疗时的目标施压时间和目标释压时间；控制器310接收到最终驱动信号，开始对患者进行治疗，在上述目标施压时间到来时，控制器310控制气源311开启、控制充气控制装置308开启、控制恒流稳压装置312的出气口313以及进气口314打开，控制排气控制装置309关闭。此时气源311开始向恒流稳压装置312充气，恒流稳压装置中的气体流入囊套5中，以一定的压力对囊套5进行充气，使得囊套5对患者的下肢及臀部进行施压，使得下肢和臀部的血液向头端返流。
在上述目标释压时间到来时，控制器310控制气源311关闭、控制充气控制装置308关闭，控制排气控制装置309开启，控制恒流稳压装置312的出气口313以及进气口314关闭。此时囊套5中气体通过排气控制装置排出。此时，受压的肢体血管开放，顺生理方向使血流加速，血流量加大，提高脉动血流剪切应力，从而改善血管内皮功能。
控制器310按上述最终驱动信号中所设定的目标施压时间和目标施压时间，重复控制囊套5充气和排气，直至整个治疗过程结束。
优选的上述气源311为低压大流量无油气泵，上述充气控制装置308为充气阀门、上述排气控制装置309为排气阀门；
优选的如图3所示，恒流稳压装置312包括出气口313、入气口314、储气室315、活塞316以及弹簧317；活塞316与弹簧317连接；出气口313通过内部导气管307与上述充气控制装置308以及排气控制装置309连通；入气口314与上述气源311连通；恒流稳压装置能够在对囊套5充气时对充气压力进行调节， 具体的，当对囊套进行充气时，储气室315中的气体通过出气口313流入囊套中，储气室内的气体压力下降，活塞316在弹簧317的作用下向外运动,储气室315的空间变小,气体压力上升，从而实现稳压功能。本发明上述实施例采用拉杆箱式配气主机进行供气，拉杆箱式配气主机可任意移动，容易随身携带。患者不需要固定在医院中进行治疗，可以在自己选定的场所进行，提高了便捷性，此外采用脉搏波信号而非心电图信号经控制终端驱动配气系统，更方便患者自助使用。
由于不同人的体型不同，不同人的脉搏波信号也有差异，因此需要经历观察、试探、粗调、微调、监测、更新等阶段，确定每个人的最佳施压时间和最佳释压时间从而提高治疗效果。
为此，在本发明一个优选的实施例中，控制终端1，用于根据脉搏波信号确定治疗过程中所对应的目标施压时间和目标释压时间，具体包括：
根据所述脉搏波信号，提取若干周期的脉搏波波形数据；
根据所述若干周期的脉搏波波形数据，计算若干个周期中脉搏波起始点到主波波峰点的平均时间，获得第一目标时间；在所述第一目标时间后的预设施压时长范围内，选取一时间点作为平均施压时间；
计算若干个周期中脉搏波起始点到波谷点的平均时间，获得平均释压时间；
将所述平均施压时间按第一预设时间间隔前移第一预设次数，并记录每次前移后的时间，将所述平均施压时间按第一预设时间间隔后移第二预设次数，并记录每次后移后的时间，根据所述平均施压时间、每次前移后的时间以及每次后移后的时间，生成施压时间序列；将所述平均释压时间按第一预设时间间隔前移第一预设次数，并记录每次前移后的时间，将所述平均释压时间按第一预设时间间隔后移第二预设次数，并记录每次后移后的时间，根据所述平均释压时间、每次前移后的时间以及每次后移后的时间，生成释压时间序列；
根据时间先后顺序逐次从所述施压时间序列提取出一施压时间，从所述释压 时间序列中提取出一释压时间，在每次提取出施压时间和释压时间后，根据当次所提取的施压时间和释压时间生成驱动信号，并将驱动信号传输至控制器，以使所述控制器在接收驱动信号后，根据驱动信号内的施压时间对所述囊套进行充气，根据驱动信号内的释压时间对所述囊套进行排气；
计算所述控制器每一次根据驱动信号完成对所述囊套控制后的脉搏波特征值，并将脉搏波特征值最大时所对应的驱动信号的施压时间作为所述目标施压时间，将脉搏波特征值最大时所对应的驱动信号的释压时间作为所述目标释压时间；其中，所述脉搏波特征值包括：脉搏主波波峰值或脉搏波主波面积。
以下对上述目标施压时间和目标释压时间的确定进行详细的说明：
在正式治疗开始前，根据患者的脉搏波信号，获取N个(优选的是10个)周期的脉搏波形数据,然后以最大值点识别为脉搏波主波的波峰点，以最小值点识别为脉搏波的波谷点，然后计算每个周期中脉搏波起始点到主波波峰点的时长，以及每个周期中脉搏波起始点到脉搏波波谷点的时长，紧接着计算N个周期脉搏波起始点到主波波峰点的时长的平均值获得一个平均时长，将这个平均时长作为上述第一目标时间；紧接着，在第一目标时间后的预设施压时长范围内，选取所述预设施压时长范围的一时间点作为平均施压时间；一般而言主波波峰点后50ms-150ms，是心脏舒张期的开始，外周血液开始回流，因此需要在主波波峰点后的50ms-150ms这个范围内开始施压才能达到良好的治疗效果，为此在本发明中，将上述预设施压时长范围设置为50ms-150ms(包括50ms及150ms),然后选取上述第一目标时间后预设施压时长范围内的一时间点，例如是100ms，即上述第一目标时间后的100ms作为平均施压时间。
计算N个周期脉搏波起始点到脉搏波波谷点的时长的平均值获得另一个平均时长，将这一个平均时长作为上述平均释压时间；
获得上述平均施压时间和上述平均释压时间后，需要进一步进行调整。
调整步骤如下：
一般而言脉搏波起始点到主波波峰点的时间正常值在70ms-110ms之间，其后的50ms-150ms是主动脉瓣关闭，舒张期开始的时间，因此以脉搏波起始点的时间点起算，上述平均施压时间应该在120ms-260ms之间；现假设上述脉搏波起始点到主波波峰点的平均时间为100ms,即上述第一目标时间为100ms,平均施压时间为上述第一目标时间后的100ms，即为200ms。
将上述平均施压时间按第一预设时间间隔，例如是50ms，前移第一预设次数(例如是1次)，以及后移第二预设次数(例如是1次)，然后会得到一个施压时间序列(150ms、200ms、250ms)。
一般而言述脉搏波起始点到脉搏波波谷点的时间正常值在480ms-1000ms之间，在此假设上述平均释压时间为750ms,
将上述平均释压时间，按第一预设时间间隔前移第一预设次数(例如是1次)，以及后移第二预设次数(例如是1次),然后得到一个释压时间序列(700ms、750ms、800ms),施压时间序列和释压时间序列中各时间按时间先后顺序一一对应。
紧接着按时间先后顺序从施压时间序列和释压时间序列中逐次提取出一施压时间和释压时间，例如第一次提取出施压时间：150ms,释压时间700ms,然后生成包含施压时间：150ms和释压时间700ms的驱动信号，将驱动信号发送给控制器310，控制器310根据这个驱动信号控制囊套5(此时囊套5还是佩戴在患者的下肢和臀部的)充气和排气，完成一个测试周期，然后计算该测试周期对应的脉搏波特征值并记录。第一个测试周期完成后，进行第二次提取，提取出施压时间：200ms，释压时间750ms，然后重复上述流程，完成第二个测试周期。以此类推，直至施压时间序列和释压时间序列内的时间都提取完毕。紧接着比对所有测试周期中脉搏波的脉搏波特征值；将脉搏波特征值最大的测试周期所对应的施压时间和释压时间作为本发明上述目标施压时间和目标释压时间。然后在正式治疗 过程时，根据目标施压时间和目标释压时间生成最终驱动信号，对囊套5进行施压和释压。
上述调整是一个粗调的阶段，在一些优选的实施例中为了取得更好的效果，可以对上述目标施压时间和上述目标释压时间，进行更加细微的调整。
在一个优选的实施例中，在完成上述调整获得目标施压时间和目标释压时间后，还可以对目标施压时间和目标释压时间进行更加细微的二次调整。具体方式与上述调整步骤相似，区别在于在进行二次调整时，上述平均施压时间替换为上述目标施压时间，将上述平均释压时间替换为目标释压时间，将上述第一预设时间间隔替换为第二预设时间间隔(例如是25ms),在二次细调整时需要保证第二预设时间间隔要小于第一预设时间间隔，这样才能够提高进一步调整的作用，经过二次调整之后，最终得到细调后的目标施压时间和细调后的目标释压时间。
在一个优选的实施例中，控制终端1还用于，在治疗过程中对患者的脉搏波特征值进行实时监测，若脉搏波特征值低于预设阈值时，则对目标施压时间和目标释压时间进行更新。在这一实施例中，通过对脉搏波特征值进行实时监测，一旦脉搏波特征值低于预设阈值，则说明患者心率脉搏在治疗过程中出现了比较大的变化，采用原有的目标施压时间和目标释压时间已经不太合适了，此时按照本发明上述二次调整步骤对目标施压时间和目标释压时间进行调整，从而提高治疗效果。
在一个优选的实施例中，控制终端1还用于，在预设的更新周期到来时，对目标施压时间和目标释压时间进行更新。上述预设更新周期可以是(10分钟)。在这一实施例中是按预设的周期进行目标施压时间和目标释压时间进行调整，从而防止由于患者在长时间的治疗过程中，由于生理变化，导致治疗效果不佳的问题，同样在进行目标施压时间和目标释压时间的更新时，可按照本发明上述二次调整步骤进行调整。
在一个优选的实施例中，控制终端1还用于，对囊套5的气压进行监测，若囊套5的气压超过预设压力阈值时，则向控制器312发送排气指令，以使控制器310在接收排气指令后，控制囊套5排气。
在一个优选的实施例中，上述外部导气管为可拆卸导气管，在不使用的时候可以拆除。
在一个优选的实施例中，箱体301还设置收纳腔。箱体301上的收纳腔可以用于放置上述囊套5、脉搏波传感器2以及外部导气管4。这样用户只需拖动拉杆箱式配气主机3，即可实现整套用于改善血管内皮功能的便携式装置的携带，更加便捷。
以上所述是本发明的优选实施方式，应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明原理的前提下，还可以做出若干改进和润饰，这些改进和润饰也视为本发明的保护范围。

Claims (6)

  1. 一种用于改善血管内皮功能的便携式装置，其特征在于，包括：拉杆箱式配气主机、控制终端、囊套、脉搏波传感器以及外部导气管；
    所述拉杆箱式配气主机包括：箱体、滑轮、拉杆、导气孔、脉搏波传感器接口、控制终端接口、控制器、气源、恒流稳压装置、充气控制装置以及排气控制装置；所述控制器、所述气源、所述恒流稳压装置、所述充气控制装置以及所述排气控制装置均设置在所述箱体内；
    所述气源与所述恒流稳压装置连通，所述恒流稳压装置与所述充气控制装置以及所述排气控制装置连通，所述充气控制装置以及排气控制装置与所述导气孔连通；所述外部导气管的一端与所述导气孔连通，所述外部导气管的另一端与所述囊套连通；
    所述控制器与所述气源、所述恒流稳压装置以及所述充气控制装置以及排气控制装置连接；
    所述控制终端通过所述控制终端接口与所述控制器连接，所述脉搏波传感器通过所述脉搏波传感器接口与所述控制器连通；
    所述脉搏波传感器，用于采集患者的脉搏波信号并将所述脉搏波信号传输至所述控制器，以使所述控制器将所述脉搏波信号传输至所述控制终端；
    所述控制终端，用于根据所述脉搏波信号确定治疗过程中所对应的目标施压时间和目标释压时间，并根据所述目标施压时间和目标释压时间生成最终驱动信号；
    所述控制器，用于在治疗过程中根据所述最终驱动信号控制所述气源、所述恒流稳压装置、所述充气控制装置以及所述排气控制装置的工作状态，对所述囊 套进行充气或排气。
  2. 如权利要求1所述的用于改善血管内皮功能的便携式装置，其特征在于，所述控制终端，用于根据所述脉搏波信号确定治疗过程中所对应的目标施压时间和目标释压时间，具体包括：
    根据所述脉搏波信号，提取若干周期的脉搏波波形数据；
    根据所述若干周期的脉搏波波形数据，计算若干个周期中脉搏波起始点到主波波峰点的平均时间，获得第一目标时间；在所述第一目标时间后的预设施压时长范围内，选取一时间点作为平均施压时间；
    计算若干个周期中脉搏波起始点到波谷点的平均时间，获得平均释压时间；
    将所述平均施压时间按第一预设时间间隔前移第一预设次数，并记录每次前移后的时间，将所述平均施压时间按第一预设时间间隔后移第二预设次数，并记录每次后移后的时间，根据所述平均施压时间、每次前移后的时间以及每次后移后的时间，生成施压时间序列；将所述平均释压时间按第一预设时间间隔前移第一预设次数，并记录每次前移后的时间，将所述平均释压时间按第一预设时间间隔后移第二预设次数，并记录每次后移后的时间，根据所述平均释压时间、每次前移后的时间以及每次后移后的时间，生成释压时间序列；
    根据时间先后顺序依次从所述施压时间序列提取出一施压时间，从所述释压时间序列中提取出一释压时间，在每次提取出施压时间和释压时间后，根据当次所提取的施压时间和释压时间生成驱动信号，并将驱动信号传输至控制器，以使所述控制器在接收驱动信号后，根据驱动信号内的施压时间对所述囊套进行充气，根据驱动信号内的释压时间对所述囊套进行排气；
    计算所述控制器每一次根据驱动信号完成对所述囊套控制后的脉搏波特征值，并将脉搏波特征值最大时所对应的驱动信号的施压时间作为所述目标施压时 间，将脉搏波特征值最大时所对应的驱动信号的释压时间作为所述目标释压时间；其中，所述脉搏波特征值包括：脉搏波主波峰值或脉搏波主波面积。
  3. 如权利要求2所述的用于改善血管内皮功能的便携式装置，其特征在于，所述控制终端还用于，在治疗过程中对患者的脉搏波特征值进行实时监测，若所述脉搏波特征值低于预设阈值时，则对所述目标施压时间和所述目标释压时间进行更新。
  4. 如权利要求2所述的用于改善血管内皮功能的便携式装置，其特征在于，所述控制终端还用于，在预设的更新周期到来时，对所述目标施压时间和所述目标释压时间进行更新。
  5. 如权利要求2所述的用于改善血管内皮功能的便携式装置，其特征在于，所述控制终端还用于，对所述囊套的气压进行监测，若所述囊套的气压超过预设压力阈值时，则向所述控制器发送排气指令，以使所述控制器在接收所述排气指令后，控制所述囊套排气。
  6. 如权利要求1所述的用于改善血管内皮功能的便携式装置，其特征在于，所述箱体还设置收纳腔。
PCT/CN2022/093469 2021-05-24 2022-05-18 一种用于改善血管内皮功能的便携式装置 WO2022247695A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202110566080.7A CN113288751B (zh) 2021-05-24 2021-05-24 一种用于改善血管内皮功能的便携式装置
CN202110566080.7 2021-05-24

Publications (1)

Publication Number Publication Date
WO2022247695A1 true WO2022247695A1 (zh) 2022-12-01

Family

ID=77324322

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2022/093469 WO2022247695A1 (zh) 2021-05-24 2022-05-18 一种用于改善血管内皮功能的便携式装置

Country Status (2)

Country Link
CN (1) CN113288751B (zh)
WO (1) WO2022247695A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113288751B (zh) * 2021-05-24 2023-06-23 中山大学附属第一医院 一种用于改善血管内皮功能的便携式装置
IT202200003455A1 (it) * 2022-02-24 2023-08-24 Eurosets Srl Attrezzatura per il trasporto di dispositivi biomedicali

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1041877A (zh) * 1988-10-21 1990-05-09 上海交通大学 通用微机全自动体外反搏装置
US20030233061A1 (en) * 2002-06-13 2003-12-18 Hui John C. K. External counterpulsation and method for minimizing end diastolic pressure
CN1647789A (zh) * 2005-02-06 2005-08-03 佛山市利强机电设备有限公司 自动跟踪调整体外反搏器最佳压力施加和释放时间的方法
CN201426830Y (zh) * 2009-06-02 2010-03-24 佛山市利通医疗设备有限公司 一种气压按摩机
CN113288751A (zh) * 2021-05-24 2021-08-24 中山大学附属第一医院 一种用于改善血管内皮功能的便携式装置

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1008881B (zh) * 1986-03-03 1990-07-25 中山医科大学生物医学工程开发中心 体外反搏和胸外心按压联合装置
CN1044197C (zh) * 1992-09-29 1999-07-21 上海市第一人民医院 全自动体外反搏治疗监护装置
CN1073403C (zh) * 1997-06-28 2001-10-24 北京工业大学 确定体外反搏过程中的最优加压时间的方法及采用该方法的体外反搏装置
CN2792415Y (zh) * 2005-04-25 2006-07-05 中山医科大学生物医学工程开发中心 血管保健康复治疗仪
CN201088579Y (zh) * 2007-08-06 2008-07-23 北京麦邦光电仪器有限公司 一种动脉硬化检测和评估装置
CN101554324B (zh) * 2008-04-07 2013-04-24 深圳迈瑞生物医疗电子股份有限公司 一种血压测量模块
CN101669817B (zh) * 2009-09-25 2013-08-28 中山大学附属第一医院 体外反搏系统及其驱动方法
CN101729780A (zh) * 2009-10-13 2010-06-09 河南平原光电有限公司 光学成像系统的自动调焦方法
WO2012005630A2 (en) * 2010-07-06 2012-01-12 Aleksey Monesovich Sudarev Method and devices proposed for the impact on the cardiovascular system
CN101995640A (zh) * 2010-09-30 2011-03-30 镇江中信科技开发有限公司 一种粗调细调相结合的快速插值焦点探索算法
CN102499873B (zh) * 2011-10-24 2013-09-18 重庆普施康科技发展有限公司 体外反搏装置充排气时间自动调节方法
CN102678682B (zh) * 2012-05-22 2015-06-10 淮海工学院 一种水下恒压差气源
CN103550053A (zh) * 2013-11-15 2014-02-05 重庆普施康科技发展有限公司 体外反搏装置治疗效果自动优化方法
CN105806481A (zh) * 2016-03-23 2016-07-27 复旦大学 一种迈克尔逊型光谱仪失调自动校准系统和方法
CN106382462B (zh) * 2016-11-18 2018-07-13 贵州望江气体有限公司 一种高压气体的充装工艺
CN107773250A (zh) * 2017-11-22 2018-03-09 江苏康尚生物医疗科技有限公司 一种自动增益控制的光电脉搏血氧仪快速调光控制方法
CN108554757B (zh) * 2017-12-20 2019-11-26 四川泰猷科技有限公司 一种功率调节电阻确定方法与装置
CN111603148A (zh) * 2020-06-02 2020-09-01 韩伟伟 一种用于急诊护理用体征测量装置
CN111700786A (zh) * 2020-07-06 2020-09-25 中山大学附属第八医院（深圳福田） 一种体外反搏康复治疗仪及其控制方法
CN112596573B (zh) * 2020-12-14 2021-10-12 成都沃特塞恩电子技术有限公司 一种功率源控制方法、装置、电子设备及存储介质
CN112773962A (zh) * 2021-02-07 2021-05-11 重庆医科大学附属儿童医院 一种新型腔静脉插管

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1041877A (zh) * 1988-10-21 1990-05-09 上海交通大学 通用微机全自动体外反搏装置
US20030233061A1 (en) * 2002-06-13 2003-12-18 Hui John C. K. External counterpulsation and method for minimizing end diastolic pressure
CN1647789A (zh) * 2005-02-06 2005-08-03 佛山市利强机电设备有限公司 自动跟踪调整体外反搏器最佳压力施加和释放时间的方法
CN201426830Y (zh) * 2009-06-02 2010-03-24 佛山市利通医疗设备有限公司 一种气压按摩机
CN113288751A (zh) * 2021-05-24 2021-08-24 中山大学附属第一医院 一种用于改善血管内皮功能的便携式装置

Also Published As

Publication number Publication date
CN113288751A (zh) 2021-08-24
CN113288751B (zh) 2023-06-23

Similar Documents

Publication Publication Date Title
WO2022247695A1 (zh) 一种用于改善血管内皮功能的便携式装置
US6589267B1 (en) High efficiency external counterpulsation apparatus and method for controlling same
US6572621B1 (en) High efficiency external counterpulsation apparatus and method for controlling same
US7048702B2 (en) External counterpulsation and method for minimizing end diastolic pressure
US6863670B2 (en) High efficiency external counterpulsation apparatus and method for controlling same
US20050137507A1 (en) Counterpulsation device using noncompressed air
CN110279574B (zh) 用于防治肌少症的局部振动装置
JP2021506466A (ja) 低血流状態を治療するために頭部および胸部を挙上するための装置
CN110327197B (zh) 用于防治肌少症的体外反搏装置
CN115444714A (zh) 一种颈部术后康复训练仪
CN110227237A (zh) 一种下肢康复训练装置及方法
CN107530223A (zh) 通过局部肢体闭塞进行远程缺血性调节的方法和装置
CN212347306U (zh) 一种复合压力治疗仪
CN210447561U (zh) 一种体外反搏气路系统
CN219207815U (zh) 一种diep乳房重建用体位垫
CN107616903A (zh) 一种新型呼吸耦联匹配抗四肢静脉血栓形成的设备
CN208405301U (zh) 下肢深静脉血栓患者护理带
CN208372107U (zh) 一种预防四肢静脉血栓的设备
CN209187704U (zh) 一种抽气罐
CN110897845A (zh) 一种空气波压力按摩治疗系统
KR20190123114A (ko) 캡슐형 체외 역박동 혈액 순환 기기 및 고압 산소 체임버
CN111420142A (zh) 一种复合压力治疗仪及其使用方法
RU2135216C1 (ru) Устройство для внешних противопульсаций (варианты)
CN116869723A (zh) 一种心脏起搏器植入的术后制动护理装置
JP2022524569A (ja) 高効率外部逆脈動システム及びシステムを使用する治療の方法

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 22810422

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 22810422

Country of ref document: EP

Kind code of ref document: A1