WO2022232610A3 - Nanoparticules décorées par un peptide pour l'enrichissement de sous-ensembles de protéines spécifiques - Google Patents

Nanoparticules décorées par un peptide pour l'enrichissement de sous-ensembles de protéines spécifiques Download PDF

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Publication number
WO2022232610A3
WO2022232610A3 PCT/US2022/027080 US2022027080W WO2022232610A3 WO 2022232610 A3 WO2022232610 A3 WO 2022232610A3 US 2022027080 W US2022027080 W US 2022027080W WO 2022232610 A3 WO2022232610 A3 WO 2022232610A3
Authority
WO
WIPO (PCT)
Prior art keywords
enrichment
subsets
specific protein
present disclosure
biological samples
Prior art date
Application number
PCT/US2022/027080
Other languages
English (en)
Other versions
WO2022232610A2 (fr
Inventor
Asim Siddiqui
Daniel Hornburg
Craig STOLARCZYK
Yina LI
Hongwei XIA
Original Assignee
Seer, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seer, Inc. filed Critical Seer, Inc.
Priority to EP22796869.0A priority Critical patent/EP4329793A2/fr
Priority to CN202280046588.7A priority patent/CN117580584A/zh
Publication of WO2022232610A2 publication Critical patent/WO2022232610A2/fr
Publication of WO2022232610A3 publication Critical patent/WO2022232610A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne une gamme de compositions et des procédés pour enrichir des sous-ensembles d'échantillons biologiques complexes. Des aspects de la présente invention concernent des particules fonctionnalisées par un peptide comprenant des affinités pour des sous-ensembles de biomolécules issues d'échantillons biologiques complexes. La présente invention concerne en outre des procédés d'utilisation de particules fonctionnalisées pour fractionner et analyser des échantillons biologiques complexes.
PCT/US2022/027080 2021-04-29 2022-04-29 Nanoparticules décorées par un peptide pour l'enrichissement de sous-ensembles de protéines spécifiques WO2022232610A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP22796869.0A EP4329793A2 (fr) 2021-04-29 2022-04-29 Nanoparticules décorées par un peptide pour l'enrichissement de sous-ensembles de protéines spécifiques
CN202280046588.7A CN117580584A (zh) 2021-04-29 2022-04-29 用于富集特定蛋白质子集的肽修饰纳米颗粒

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163181765P 2021-04-29 2021-04-29
US63/181,765 2021-04-29

Publications (2)

Publication Number Publication Date
WO2022232610A2 WO2022232610A2 (fr) 2022-11-03
WO2022232610A3 true WO2022232610A3 (fr) 2022-12-08

Family

ID=83848871

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2022/027080 WO2022232610A2 (fr) 2021-04-29 2022-04-29 Nanoparticules décorées par un peptide pour l'enrichissement de sous-ensembles de protéines spécifiques

Country Status (3)

Country Link
EP (1) EP4329793A2 (fr)
CN (1) CN117580584A (fr)
WO (1) WO2022232610A2 (fr)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4514824B2 (ja) * 2009-02-23 2010-07-28 古河電気工業株式会社 イムノクロマト法試薬用標識シリカナノ粒子の製造方法、イムノクロマト法用コンジュゲートパッドの製造方法、及びそれを用いたイムノクロマト法用テストストリップの使用方法
US20100279382A1 (en) * 2004-05-21 2010-11-04 The Institute For Systems Biology Compositions and methods for quantification of serum glycoproteins
US20140302121A1 (en) * 2011-07-05 2014-10-09 Wet Inc. Cannabinoid Receptor Binding Agents, Compositions and Methods
US8933197B2 (en) * 2007-08-15 2015-01-13 Amunix Operating Inc. Compositions comprising modified biologically active polypeptides
US20180148778A1 (en) * 2014-12-16 2018-05-31 Garvan Institute Of Medical Research Sequencing controls
WO2018204392A1 (fr) * 2017-05-02 2018-11-08 Stanford Burnham Prebys Medical Discovery Institute Peptide liant des monocytes/macrophages associés à une tumeur et procédés d'utilisation associés
WO2020096631A2 (fr) * 2018-11-07 2020-05-14 Seer, Inc. Compositions, procédés et systèmes d'analyse de couronne protéique et leurs utilisations

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100279382A1 (en) * 2004-05-21 2010-11-04 The Institute For Systems Biology Compositions and methods for quantification of serum glycoproteins
US8933197B2 (en) * 2007-08-15 2015-01-13 Amunix Operating Inc. Compositions comprising modified biologically active polypeptides
JP4514824B2 (ja) * 2009-02-23 2010-07-28 古河電気工業株式会社 イムノクロマト法試薬用標識シリカナノ粒子の製造方法、イムノクロマト法用コンジュゲートパッドの製造方法、及びそれを用いたイムノクロマト法用テストストリップの使用方法
US20140302121A1 (en) * 2011-07-05 2014-10-09 Wet Inc. Cannabinoid Receptor Binding Agents, Compositions and Methods
US20180148778A1 (en) * 2014-12-16 2018-05-31 Garvan Institute Of Medical Research Sequencing controls
WO2018204392A1 (fr) * 2017-05-02 2018-11-08 Stanford Burnham Prebys Medical Discovery Institute Peptide liant des monocytes/macrophages associés à une tumeur et procédés d'utilisation associés
WO2020096631A2 (fr) * 2018-11-07 2020-05-14 Seer, Inc. Compositions, procédés et systèmes d'analyse de couronne protéique et leurs utilisations

Also Published As

Publication number Publication date
WO2022232610A2 (fr) 2022-11-03
CN117580584A (zh) 2024-02-20
EP4329793A2 (fr) 2024-03-06

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