WO2022169336A3 - 류코노스톡 시트래움 균주를 유효성분으로 포함하는 섬유화증의 예방 또는 치료용 약학 조성물 - Google Patents

류코노스톡 시트래움 균주를 유효성분으로 포함하는 섬유화증의 예방 또는 치료용 약학 조성물 Download PDF

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Publication number
WO2022169336A3
WO2022169336A3 PCT/KR2022/001869 KR2022001869W WO2022169336A3 WO 2022169336 A3 WO2022169336 A3 WO 2022169336A3 KR 2022001869 W KR2022001869 W KR 2022001869W WO 2022169336 A3 WO2022169336 A3 WO 2022169336A3
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Prior art keywords
fibrosis
prevention
treatment
active ingredient
pharmaceutical composition
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PCT/KR2022/001869
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English (en)
French (fr)
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WO2022169336A2 (ko
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진화섭
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주식회사 리스큐어바이오사이언시스
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Priority claimed from KR1020220014809A external-priority patent/KR20220114489A/ko
Application filed by 주식회사 리스큐어바이오사이언시스 filed Critical 주식회사 리스큐어바이오사이언시스
Priority to CN202280014034.9A priority Critical patent/CN117320737A/zh
Priority to JP2023547882A priority patent/JP2024506625A/ja
Priority to EP22750085.7A priority patent/EP4289439A2/en
Priority to US18/276,150 priority patent/US20240115628A1/en
Priority to CA3207719A priority patent/CA3207719A1/en
Publication of WO2022169336A2 publication Critical patent/WO2022169336A2/ko
Publication of WO2022169336A3 publication Critical patent/WO2022169336A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/06—Treating cheese curd after whey separation; Products obtained thereby
    • A23C19/061—Addition of, or treatment with, microorganisms
    • A23C19/062—Addition of, or treatment with, microorganisms using only lactic acid bacteria, e.g. pediococcus, leconostoc or bifidus sp., or propionic acid bacteria; Treatment with non-specified acidifying bacterial cultures
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1236—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt using Leuconostoc, Pediococcus or Streptococcus sp. other than Streptococcus Thermophilus; Artificial sour buttermilk in general
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/20—Feeding-stuffs specially adapted for particular animals for horses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/50—Feeding-stuffs specially adapted for particular animals for rodents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Physiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Insects & Arthropods (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

본 발명은 류코노스톡 시트래움 (Leuconostoc citreum) 균주 또는 이의 배양물을 유효성분으로 포함하는 섬유화증(fibrosis), 구체적으로는 폐섬유화증, 신장섬유화증 또는 간섬유화증에 대한 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명에 따른 조성물은 여러 섬유화증에 대해 우수한 예방 및 치료 효과를 나타내므로, 사람 또는 동물의 섬유화증의 치료, 예방 또는 개선 등의 용도를 위한 조성물로서 유용하게 이용될 수 있다.
PCT/KR2022/001869 2021-02-08 2022-02-07 류코노스톡 시트래움 균주를 유효성분으로 포함하는 섬유화증의 예방 또는 치료용 약학 조성물 WO2022169336A2 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN202280014034.9A CN117320737A (zh) 2021-02-08 2022-02-07 包含柠檬明串珠菌菌株作为有效成分的用于预防或治疗纤维化的药物组合物
JP2023547882A JP2024506625A (ja) 2021-02-08 2022-02-07 ロイコノストック・シトレウム菌株を有効成分として含む線維症の予防または治療用医薬組成物
EP22750085.7A EP4289439A2 (en) 2021-02-08 2022-02-07 Pharmaceutical composition for prevention or treatment of fibrosis comprising leuconostoc citreum strain as active ingredient
US18/276,150 US20240115628A1 (en) 2021-02-08 2022-02-07 Pharmaceutical composition for preventing or treating fibrosis comprising leuconostoc citreum strain as active ingredient
CA3207719A CA3207719A1 (en) 2021-02-08 2022-02-07 Pharmaceutical composition for preventing or treating fibrosis comprisi ng leuconostoc citreum strain as active ingredient

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20210017794 2021-02-08
KR10-2021-0017794 2021-02-08
KR10-2022-0014809 2022-02-04
KR1020220014809A KR20220114489A (ko) 2021-02-08 2022-02-04 류코노스톡 시트래움 균주를 유효성분으로 포함하는 섬유화증의 예방 또는 치료용 약학 조성물

Publications (2)

Publication Number Publication Date
WO2022169336A2 WO2022169336A2 (ko) 2022-08-11
WO2022169336A3 true WO2022169336A3 (ko) 2022-10-06

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Application Number Title Priority Date Filing Date
PCT/KR2022/001869 WO2022169336A2 (ko) 2021-02-08 2022-02-07 류코노스톡 시트래움 균주를 유효성분으로 포함하는 섬유화증의 예방 또는 치료용 약학 조성물

Country Status (5)

Country Link
US (1) US20240115628A1 (ko)
EP (1) EP4289439A2 (ko)
JP (1) JP2024506625A (ko)
CA (1) CA3207719A1 (ko)
WO (1) WO2022169336A2 (ko)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012149026A (ja) * 2011-01-14 2012-08-09 Genmont Biotech Inc プロバイオティクス菌株ｇｍ−２６３（ａｄｒ−１）が糖尿病による腎線維化の治療に用いられる組成物及びその用途
US20150150918A1 (en) * 2013-12-02 2015-06-04 New Bellus Enterprises Co., Ltd. Method for treating or preventing heart diseases
KR102032982B1 (ko) * 2019-02-28 2019-10-16 한국식품연구원 류코노스톡 시트래움 WiKim0104를 포함하는 비만 또는 지방간 질환의 예방, 개선 또는 치료용 조성물
WO2020081742A2 (en) * 2018-10-17 2020-04-23 SciBac Inc. Live biotherapeutics to treat and prevent lung conditions
KR102154255B1 (ko) * 2020-05-22 2020-09-09 (주)녹십자웰빙 유산균을 함유하는 미세먼지 자극에 의한 호흡기 질환 또는 염증 질환 치료용 조성물

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012149026A (ja) * 2011-01-14 2012-08-09 Genmont Biotech Inc プロバイオティクス菌株ｇｍ−２６３（ａｄｒ−１）が糖尿病による腎線維化の治療に用いられる組成物及びその用途
US20150150918A1 (en) * 2013-12-02 2015-06-04 New Bellus Enterprises Co., Ltd. Method for treating or preventing heart diseases
WO2020081742A2 (en) * 2018-10-17 2020-04-23 SciBac Inc. Live biotherapeutics to treat and prevent lung conditions
KR102032982B1 (ko) * 2019-02-28 2019-10-16 한국식품연구원 류코노스톡 시트래움 WiKim0104를 포함하는 비만 또는 지방간 질환의 예방, 개선 또는 치료용 조성물
KR102154255B1 (ko) * 2020-05-22 2020-09-09 (주)녹십자웰빙 유산균을 함유하는 미세먼지 자극에 의한 호흡기 질환 또는 염증 질환 치료용 조성물

Also Published As

Publication number Publication date
JP2024506625A (ja) 2024-02-14
US20240115628A1 (en) 2024-04-11
CA3207719A1 (en) 2022-08-11
EP4289439A2 (en) 2023-12-13
WO2022169336A2 (ko) 2022-08-11

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