WO2022141375A1 - Composition for caring for kertatin materials - Google Patents

Composition for caring for kertatin materials Download PDF

Info

Publication number
WO2022141375A1
WO2022141375A1 PCT/CN2020/142048 CN2020142048W WO2022141375A1 WO 2022141375 A1 WO2022141375 A1 WO 2022141375A1 CN 2020142048 W CN2020142048 W CN 2020142048W WO 2022141375 A1 WO2022141375 A1 WO 2022141375A1
Authority
WO
WIPO (PCT)
Prior art keywords
weight
composition
composition according
acid
polyols
Prior art date
Application number
PCT/CN2020/142048
Other languages
English (en)
French (fr)
Inventor
Chi Ma
Xiuxia Wang
Original Assignee
L'oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by L'oreal filed Critical L'oreal
Priority to CN202080108286.9A priority Critical patent/CN116669688A/zh
Priority to PCT/CN2020/142048 priority patent/WO2022141375A1/en
Priority to FR2101420A priority patent/FR3118579B1/fr
Publication of WO2022141375A1 publication Critical patent/WO2022141375A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients
    • A61K2800/31—Anhydrous
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/592—Mixtures of compounds complementing their respective functions
    • A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18

Definitions

  • the present invention relates to a cosmetic composition for caring for keratin materials, and in particular the skin. Further, the present invention relates to use of the same, and in particular as a skincare product.
  • Free radicals are highly reactive molecules with unpaired electrons that can directly damage various cellular membranes, lipids, proteins, RNA and DNA. The damaging effects of these reactive oxygen species are induced internally during normal metabolism and externally through various oxidative stresses. UV exposure and environmental pollution can accelerate skin aging by producing free radicals in skin. Antioxidants protect cells from the damage of oxidative stress by scavenging free radicals and inhibiting following oxidation reactions.
  • the topical application of antioxidants is broadly used in skin care products to prevent skin aging.
  • compositions and methods of using the compositions to benefit skin relate to compositions and methods of using the compositions to benefit skin.
  • the compositions improve the appearance of skin and provide multiple anti-aging and other benefits to the skin.
  • the compositions are unique in their ability to provide strong antioxidizing efficacy with slippery sensory.
  • anhydrous composition comprising components A) at least two bi-functional antioxidants selected from acidic hydroxyl-containing compounds, serving also at least as whitening agents; and B) at least two polyols which are liquid at room temperature, wherein at least one of the polyols is a C2-C6 polyol having 2 or 3 hydroxyl groups.
  • component A) i.e., bi-functional antioxidants, is used in an amount of 0.1-40%by weight relative to the total weight of the composition.
  • composition according to the invention has in particular a fluid and light texture, suitable for use in ampoule.
  • the composition according to the invention is especially stable over time, especially against UV radiation.
  • the subject of the invention is also a process for caring for or making up keratin materials, in particular skin, e.g., face, comprising the topical application to the keratin materials of the composition according to the present invention.
  • the invention also relates to the use of the composition according to the present invention for caring for or making up keratin materials, particularly for caring the skin.
  • the composition according to the present invention shows particularly an improved anti-singlet oxygen effect. Accordingly, the composition according to the present invention, particularly in the case of being used in an ampoule product, is superior on radiant bright skin and/or smooth nourished skin.
  • the “keratin material” is the skin.
  • skin we intend all the body skin.
  • the keratin material is the face, or the neck, especially the face.
  • topical application it meant that the composition is applied or spread onto the surface of the keratin materials, e.g., at least one zone of the skin.
  • a numeric range is defined with a lower and an upper limits when needed, such as one or more lower limits and one or more upper limits are given to form a range optionally along with one or more preferred ranges.
  • a given range can be defined by selecting a lower limit and an upper limit that define the boundaries of the given range. All ranges defined in this manner are inclusive and combinable, that is, any lower limit can be combined with any upper limit to form a range, as long as the lower and upper limits are provided to modify the same subject. For example, when ranges of 60-110 and 80-120 are listed for a specific subject, it is to be understood that ranges 60-120 and 80-110 are also contemplated and encompassed. Further, if the lower limits listed are 1 and 2 and the upper limits are listed as 3, 4 and 5, the following ranges are all predictable and within the scope of the present disclosure: 1-3, 1-4, 1-5, 2-3, 2-4 and 2-5.
  • anhydrous composition means absence of water, or the presence of water in such an amount those skilled can determine it as free or substantially free of water.
  • an “anhydrous" composition according to the present invention may comprise less than 2%, preferably less than 0.5%by weight of water relative to the total weight of the composition. Where appropriate, such small amounts of water may be provided by ingredients of the composition that comprise it in residual amount, but are not deliberately provided.
  • the present invention is directed to a composition for caring for keratin materials, comprising, consisting essentially of, or consisting of the components of:
  • composition is anhydrous
  • composition according to the present invention comprises component A) , at least two bi-functional antioxidants selected from acidic hydroxyl-containing compounds, which also serves at least as whitening agents for the purpose of the present invention.
  • a free hydroxyl group is relatively readily to be oxidized.
  • an antioxidant containing at least one hydroxyl group is highly interested.
  • the bi-functional antioxidant can be anthocyanin containing a hydroxyl group.
  • Anthocyanins and their derivatives are antioxidants.
  • Anthocyanins comprise a class of flavonoid compounds responsible for the red, purple and blue colors of many fruits, vegetables, grains and flowers, which are naturally occurring water-soluble compounds.
  • anthocyanins are collagenase inhibitors. Inhibition of collagenase helps prevent and reduce wrinkles caused by skin collagen reduction, increase skin elasticity, and the like.
  • Anthocyanins can be obtained from any part of a variety of plant sources, such as fruits, flowers, stems, leaves, roots, bark or seeds.
  • the antioxidant can include one or more betaine. Betatin, similar to anthocyanins, is available from natural sources and is an antioxidant.
  • the bi-functional antioxidant may be a phenylpropanoid containing a hydroxyl group (a derivative of cinnamic acid) .
  • Phenylpropanoids include: caffeic acid, ferulic acid, trans-ferulic acid (including its antioxidant pharmacore 2, 6-dihydroxy acetophenome) , 5-hydroxyferic acid, sinapic acid. Without limiting the mode of action of the present invention, phenylpropanoids can neutralize free radicals.
  • the bi-functional antioxidant can be tannin.
  • Useful tannins include: tannins, Terflavin B, Glucogallin, Dgallic acid, and Quercitannic acid.
  • the bi-functional antioxidant may be organic acids containing a hydroxyl group, such as gallic acid, ellagic acid, cichoric acid, chlorogenic acid, rosmarinic acid, protocatechuic acid, or ⁇ -hydroxy acids, such as lactic acid and glycolic acid and derivatives thereof as well as the acids listed in the category of phenylpropanoid above.
  • organic acids containing a hydroxyl group such as gallic acid, ellagic acid, cichoric acid, chlorogenic acid, rosmarinic acid, protocatechuic acid, or ⁇ -hydroxy acids, such as lactic acid and glycolic acid and derivatives thereof as well as the acids listed in the category of phenylpropanoid above.
  • the bi-functional antioxidant may be vitamin C or derivatives thereof containing a hydroxyl group, including ascorbic acid, sodium ascorbate, ascorbyl glucoside, glucosamine ascorbate, ascorbyl acetate, and the like.
  • a hydroxyl group including ascorbic acid, sodium ascorbate, ascorbyl glucoside, glucosamine ascorbate, ascorbyl acetate, and the like.
  • plants derived from a large amount of vitamin C such as extracts of Myrciaria dubia, acerola, emblica officinalis, and bioflavonoids from rose hips and citrus, including Water-soluble bioflavonoids, e.g., hesperidin methyl chalcone.
  • bi-functional antioxidant may comprise hydroxytyrosolrutin, sesame phenol, polyunsaturated fatty acids and sulfur-based antioxidants containing a hydroxyl group.
  • one of the at least two bi-functional antioxidants concurrently used may be a vitamin or a derivative thereof, such as vitamin C or derivatives thereof.
  • the vitamin or a derivative thereof, if any may be present in an amount of 1-30%by weight, preferably 5-25%by weight, or 7-18%by weight, relative to the total weight of the composition.
  • one of the at least two bi-functional antioxidants may be an organic acid containing hydroxyl, such as, caffeic acid, ferulic acid, trans-ferulic acid, sinapic acid, gallic acid , ellagic acid, cichoric acid, chlorogenic acid, rosmarinic acid, protocatechuic acid, lactic acid and/or glycolic acid.
  • organic acid containing hydroxyl if any, may be present in an amount of 0.01-20%by weight, preferably 0.1-15%by weight, or 0.5-3%by weight, relative to the total weight of the composition.
  • the component A) may be present in an amount of 0.01-40%by weight, preferably 0.1-35%by weight, 1-30%by weight, or 5-20%by weight, relative to the total weight of the composition.
  • the composition according to the present invention comprises a polyol, which is liquid at ambient temperature (25°C. ) , preferably selected in particular from polyols having in particular from 2 to 20 carbon atoms, preferably having from 2 to 10 carbon atoms, and preferentially having from 2 to 6 carbon atoms, such as glycerin, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, dipropylene glycol, and diethylene glycol.
  • a polyol which is liquid at ambient temperature (25°C. ) , preferably selected in particular from polyols having in particular from 2 to 20 carbon atoms, preferably having from 2 to 10 carbon atoms, and preferentially having from 2 to 6 carbon atoms, such as glycerin, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, dipropylene glycol, and diethylene glycol.
  • the composition according to the present invention may comprise concurrently at least two polyols.
  • at least one of the polyols is a C2-C6 polyol having 2 or 3 hydroxyl groups.
  • At least two of, preferably all of, the polyols are lower alcohols, preferably each having from 2 to 6 carbon atoms.
  • At least two polyols each comprise 2 or 3 hydroxyl groups, preferably each having from 2 to 6 carbon atoms.
  • At least two of, preferably all of, the polyols are each derivatives of a same alkane.
  • a combination of ethylene glycol and diethylene glycol, which are deemed as derivatives of ethane can be used.
  • a combination of two, three, or four of propylene glycol, dipropylene glycol, glycerin, and diglycerin which are each deemed as derivatives of propane, can be used.
  • component A) involves at least two bi-functional antioxidants selected from acidic hydroxyl-containing compound, which comprise hydroxyl group, as well as optionally carboxyl group. Accordingly, for favorable dissolution and/or stability, the at least two polyols concurrently used are specifically selected matching the component A) , especially matching the hydroxyl arrangement thereof.
  • one polyol of the at least two polyols concurrently used can have at least two adjacent hydroxyl groups, such as ethylene glycol, 1, 2-propylene glycol or glycerin; while the other polyol of the at least two polyols concurrently used can have non-adjacent hydroxyl groups, e.g., 1, 3-propylene glycol, or even as-far-distant-as-possible hydroxyl groups, e.g., dipropylene glycol.
  • Examples of at least two polyols concurrently used can be made to a combination of dipropylene glycol and glycerin; a combination of propylene glycol, dipropylene glycol, and glycerin; and a combination of propylene glycol, dipropylene glycol, glycerin, and diglycerin.
  • the at least two polyols concurrently used in the component B) can be used in similar amounts.
  • the at least two polyols concurrently used can each represents 20-55%by weight, preferably 30-50%by weight, or 40-50%by weight, relative to the total weight of the component B) .
  • the component B) may be present in an amount of 60-99.99%by weight, preferably 65-99.9%by weight, 70-99%by weight, or 80-95%by weight, relative to the total weight of the composition.
  • the composition according to the present invention is essentially in an anhydrous form.
  • water or moisture is preferably avoided to be included in the composition; however, it is easily understood by those skilled that water may not be 100%removed.
  • water may be provided by ingredients of the composition that contain it in residual amount, may be incorporated during the production, or may be absorbed from ambient during production and/or storage.
  • anhydrous means absence of water, or the presence of water in such an amount that those skilled can determine it as free or substantially free of water.
  • an “anhydrous” composition according to the present invention may comprise less than 2%, preferably less than 0.5%by weight of water, relative to the total weight of the composition.
  • an “anhydrous” composition according to the present invention does not comprise a detectable amount of water, wherein the “detectable amount” means an amount that can be detected by a device conventionally used in the art to measure the water content.
  • the components A) and B) are subjected to a water removal step before being incorporated into the composition of the present invention.
  • the technical means for the water removal is not particularly limited, as long as the composition obtained is "anhydrous" .
  • composition according to the present invention can optionally comprise an additional antioxidant other than those specified for component A) according to the present invention.
  • the additional antioxidants used may include natural exogenous phytochemical antioxidants such as phenols and carotenoids.
  • the additional antioxidant can include flavonoids.
  • Flavonoids constitute a large class of more than 5,000 polyphenolic phytochemicals with antioxidant properties that act by direct free radical scavenging. Flavonoids have anti-inflammatory, antibacterial, antiviral, anti-allergic, anti-mutagenic, anti-thrombotic, anti-tumor and vasodilating effects and these methods of action can also be used to prevent, alleviate or eliminate oxidative damage from dental instruments. Flavonoids also exhibit chelation properties with metal ions and can mitigate oxidative damage from metal ions by chelating ions. The formation and stability of flavonoid-metal chelate is dependent on the function of the structure. Flavonoids having a catechol moiety and having a hydrogen bond between the hydroxyl groups at the 5-position and the 3-position have chelation properties.
  • Sesamum indicum or lignan may also be added. Sesame and its lignans (fibrous compounds associated with sesame) act as antioxidants. Sesame seed lignan significantly enhances vitamin E activity.
  • the flavonoid may be a flavanone (a derivative of 2, 3-dihydro-2-phenylbenzopyran-4-one) .
  • Flavanones include: scutellarin, eriodictin, hesperetin, hesperidin, sylvestre, isosakuranetin, naringenin, naringin, pinocin, tangrin (poncirin) ) , sakuranetin, sakura glycosides and 7-O-methyl ergophenol (Sterubin) .
  • the flavonoid may be a dihydroflavonol (a derivative of 3-hydroxy-2, 3-dihydro-2-phenylbenzopyran-4-one) .
  • Flavanols include: taxifolin, Aromadedrin, Chrysandroside A, Chrysandroside B, Xeractinol, astilbin, and flavonol.
  • the flavonoid may be a flavonoid (a derivative of 2-phenylbenzopyran-4-one) .
  • Flavonoids include: Apigenin, luteolin, tangeritin, Chrysin, baicalein, wild baicalein, wogonin, synthetic flavonoids: Diosmin and flavonoids ester.
  • the flavonoid may be a flavonol (a derivative of 3-hydroxy-2-phenylbenzopyran-4-one) .
  • Flavonols include: 3-hydroxyflavone, rhodoxanthin, quercetin, galangin, cotton dermatan, kaempferol, kaempferol, isorhamnetin, mulberry pigment, myricetin, naringin (Natsudaidain) , Muskyl flavonol (Pachypodol) , quercetin, methyl rhamnosin, rhamnetin, azalein, hyperoside, isoquercetin, kaempferol, myricetin, suede Glycosides, Robinin, Rutin, Spiraea, Xanthorhamnin, Amurensin, Icariin and Tracuridine.
  • the flavonoid may be a flavan-3-ol (a derivative of 2-phenyl-3, 4-dihydro-2H-benzopyran-3-ol) .
  • Flavan-3-ol includes: catechin, epicatechin, epigallocatechin, epicatechin gallate, epigallocatechin gallate, epiafzelechin, Fisetinidol, Guibourtinidol, Mesquitol and Robinetinidol.
  • the flavonoid may be a flavan-4-ol (a derivative of 2-phenylchroman-4-ol) .
  • Flavan-4-ols include: Apiforol and Luteoforol.
  • the flavonoid may be an isoflavone (a derivative of 3-phenylbenzopyran-4-one) .
  • Isoflavones include: genistein, daidzein, garbanin A, formononetin, and equol metabolites from daidzein.
  • the additional antioxidant may be anthocyanin (a derivative of 2-phenylbenzopyranoside cation) .
  • Anthocyanins include: Aurantinidin, cyanidin, delphinidin, Europinidin, Luteolinidin, Pelargonidin, Malvidin, Peonyidin (Peonidin) ) , morning glory pigment (Petunidin) , rose pigment (Rosinidin) and xanthone.
  • the additional antioxidant may be dihydrochalcone (a derivative of 1, 3-diphenyl-1-propanone) .
  • Dihydrochalcone includes: phloretin, dihydrochalcone phloridin cisplatin, Aspalathin, naringin dihydrochalcone, neohesperidin dihydrochalcone and Nothofagin.
  • the mode of action of the present invention is not limited, but dihydrochalcone can exert an antioxidant effect by reducing active radicals such as active oxygen and reactive nitrogen species.
  • the additional antioxidant may be chalcone (a derivative of 1, 3-diphenyl-2-propen-1-one) .
  • Chalcone includes: zirconia, Okanin, safflower, Marein, Sophoradin, Xanthohumol, Flavokvain A, Flavokavain B, Flavokavin C and Synthetic Safalcone.
  • the additional antioxidant may be curcuminoid.
  • Curcuminoids include: curcumin, demethoxycurcumin, bis-demethoxycurcumin, tetrahydrocurcumin, and tetrahydrocurcumin. Curcumin and tetrahydrocurcumin can be derived from the rhizome of turmeric. Tetrahydrocurcumin, a metabolite of curcumin, has been found to be a more potent antioxidant and more stable than curcumin.
  • the additional antioxidant can be a stilbenoid.
  • the mites include: resveratrol, red sandalwood and paclitaxel.
  • Resveratrol can include, but is not limited to, 3, 5, 4'-trihydroxyindole, 3, 4, 3', 5'-tetrahydroxyindole (cetotriol) , 2, 3', 4, 5'-Tetrahydroxyindole (oxidized resveratrol) , 4, 4'-dihydroxyindole and its alpha and beta glucoside, galactoside and mannoside derivatives.
  • the additional antioxidant may be coumarin (a derivative of 2H-benzopyran-2-one) .
  • Coumarins include: 4-hydroxycoumarin, umbelliferone, Aesculetin, Herniarin, Auraptene, and dicoumarin.
  • the additional antioxidant can be a carotenoid.
  • Carotenoids include: beta-carotene, alpha-carotene, gamma-carotene, beta-cryptoxanthin, lycopene, lutein and idebenone.
  • the additional antioxidant may be: xanthone, butylated hydroxytoluene, 2, 6-di-tert-butylphenol, 2, 4-dimethyl-6-tert-butylphenol, eugenol, acetylcysteine, S-allylcysteine, pyridone (Barbigerone) , chebulagic acid, edaravone, ethoxyquin, idebenone, melatonin, N-acetyl serotonin, nordihydroguaiac acid, Oleotanthal, oleuropein, Paradol, paclitaxel, probucol, propyl gallate, pyrithione, flax lignan diglucoside, sesamin, Silybin, silymarin, theaflavins, theaflavins digallate, Thmoquinone, Trolox, tyrosol.
  • Sesamum indicum or sesame lignan can also be used. Sesame and its lignans (fibrous compounds associated with sesame) act as antioxidants. Sesame seed lignan significantly enhances vitamin E activity.
  • carotenoids especially lutein types
  • lutein-type carotenoids include molecules such as lutein, canthaxantin, cryptoxanthin, zeaxanthin and astaxanthin.
  • Lutein compounds protect compounds such as vitamin A, vitamin E and other carotenoids.
  • the additional antioxidant described above can be present according to the invention in an amount of 0.001-10%by weight, preferably 0.1-7%by weight, or preferably 0.5-5%by weight, relative to the total weight of the composition of the present invention.
  • composition according to the present invention may optionally comprise a preservative.
  • the preservative useful according to the present invention can be any one conventionally used for cosmetics, in particular for ampoule products.
  • preservatives can be used according to the present invention comprise methylchloroisothiazolinone, imidazolidinyl urea, derivatives of hydantoin, such as DMDMH, parahydroxybenzoate ester, phenoxyethanol, benzyl alcohol, chlorphenesin, benzoic acid and a salt thereof, such as sodium benzoate, potassium sorbate, hydroxyacetophenone, amino-acid based preservative, sorbitan octanate, glycerol caprylate and the like.
  • hydantoin such as DMDMH, parahydroxybenzoate ester, phenoxyethanol, benzyl alcohol, chlorphenesin, benzoic acid and a salt thereof, such as sodium benzoate, potassium sorbate, hydroxyacetophenone, amino-acid based preservative, sorbitan octanate, glycerol caprylate and the like.
  • the preservative can be present according to the invention in an amount 0.01-5%, preferably 0.01%-3%, preferably 0.01%-1%, relative to the total weight of the composition of the present invention.
  • carboxyvinyl polymers such as (Carbomers) and Pemulen such as Pemulen and Pemulen (acrylate/C10-C30-alkylacrylate copolymer)
  • polyacrylamides for example crosslinked copolymers sold under the names Sepigel (CTFA name: polyacrylamide/C13-14 isoparaffin /Laureth 7) or Simulgel 600 (CTFA name: acrylamide /sodium acryloyldimethyltaurate copolymer/isohexadecane/polysorbate 80) by the company Seppic
  • the composition according to the invention comprises at least one optionally crosslinked and/or neutralized 2-acrylamido-2-methylpropanesulfonic acid polymer and copolymer, such as polyacrylic acid 2-acrylamido-2-methylpropanesulfonic acid and or at least one carboxyvinyl polymer such as carbomers.
  • the composition according to the invention comprises the polyacid 2-acrylamido-2-methylpropanesulphonic sold by the company Hoechst under the trade name "Hostacerin " (CTFA name: ammonium polyacryloyldimethyltaurate) and at least one carboxyvinyl polymer such as the (Carbomers) .
  • the gelling agents may be present in the composition according to the invention in particular in an amount of 0.1%-3%by weight, or particularly 0.5%-2%by weight, relative to the total weight of the composition.
  • the dosage forms dedicated to topical application may also comprise adjuvants which are customary in the cosmetic, pharmaceutical and/or dermatological field, such as gelling agents, hydrophilic or lipophilic active agents, fragrances, fillers, filters, pH adjusters, odor absorbers and dyes.
  • adjuvants which are customary in the cosmetic, pharmaceutical and/or dermatological field, such as gelling agents, hydrophilic or lipophilic active agents, fragrances, fillers, filters, pH adjusters, odor absorbers and dyes.
  • the amounts of these various adjuvants are those conventionally used in the field under consideration, and for example from 0.01 to 20%of the total weight of the composition. These adjuvants, depending on their nature, can be introduced into the aqueous phase.
  • composition according to the invention may advantageously comprise one or more additional active ingredients, in particular cosmetic, dermatological or pharmaceutical.
  • an additional active ingredient is an active ingredient other than component A) present in the composition and the other active agents specifically defined above.
  • such additional active ingredient, cosmetic, dermatological or pharmaceutical may be intended to exert a cosmetic, care or hygiene effect on keratin materials such as skin, including face, hair, eyelashes, scalp and/or leather hairy, and preferentially on the skin.
  • composition according to the invention may further comprise an active ingredient having an anti-aging activity, or a hydration activity.
  • compositions are generally present in the composition in a content of 0.0001%-20%by weight and preferably 0.01%-10%by weight relative to the total weight of said composition.
  • compositions according to the invention can be manufactured by known processes, generally used in the cosmetic or dermatological field.
  • composition according to the invention finds its application in a large number of treatments for keratin materials such as the skin, the scalp or the mucous membranes (lips) , and more particularly the skin, in particular in caring for the skin, to nourish the skin, prevent the loss of transepidermal water and/or protect the skin.
  • the subject of the invention is also a process for caring for or making up keratin materials, comprising the application to the keratin materials of a composition as defined above.
  • the subject of the invention is a process for treating dry and/or rought skin, comprising the application to the skin of a composition as defined above.
  • the subject of the invention is a process for treating aged skin, comprising the application to the skin of a composition as defined above.
  • the invention also relates to the use of a composition as defined above, for caring for or making up keratin materials.
  • the composition is suitable for the treatment of dry skin.
  • the composition is suitable for the treatment of aged skin.
  • compositions according to the invention are given by way of illustration and without limitation.
  • the compounds are indicated in chemical name or INCI name.
  • compositions/formulas described below are expressed in %by weight, relative to the total weight of each composition/formula, unless otherwise indicated.
  • Table 1 Compositions of Example 1 of the Invention and Comparative Examples 1-2;

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
PCT/CN2020/142048 2020-12-31 2020-12-31 Composition for caring for kertatin materials WO2022141375A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN202080108286.9A CN116669688A (zh) 2020-12-31 2020-12-31 用于护理角蛋白材料的组合物
PCT/CN2020/142048 WO2022141375A1 (en) 2020-12-31 2020-12-31 Composition for caring for kertatin materials
FR2101420A FR3118579B1 (fr) 2020-12-31 2021-02-15 Composition pour prendre soin de matieres keratineuses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2020/142048 WO2022141375A1 (en) 2020-12-31 2020-12-31 Composition for caring for kertatin materials

Publications (1)

Publication Number Publication Date
WO2022141375A1 true WO2022141375A1 (en) 2022-07-07

Family

ID=82258803

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2020/142048 WO2022141375A1 (en) 2020-12-31 2020-12-31 Composition for caring for kertatin materials

Country Status (3)

Country Link
CN (1) CN116669688A (zh)
FR (1) FR3118579B1 (zh)
WO (1) WO2022141375A1 (zh)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004203835A (ja) * 2002-12-26 2004-07-22 Nisshin Kagaku Kk フェルラ酸含有組成物
WO2014059225A1 (en) * 2012-10-12 2014-04-17 L'oreal Cosmetic compositions containing at least one flavonoid and ferulic acid
WO2017172519A1 (en) * 2016-03-31 2017-10-05 L'oreal Photo-stabilized compositions and methods of use
CN107638331A (zh) * 2017-08-31 2018-01-30 澳宝化妆品（惠州）有限公司 一种修护皮肤屏障且抵抗自由基的保湿乳液
WO2018081790A1 (en) * 2016-10-31 2018-05-03 L'oreal Compositions containing phenolic compounds having synergistic antioxidant benefits
US10137072B2 (en) * 2016-03-31 2018-11-27 L'oreal Methods and compositions for providing broad spectrum photo protection using antioxidants
WO2020099664A1 (en) * 2018-11-15 2020-05-22 L'oreal Composition comprising a cinnamic acid derivative and a nonassociative nonionic cellulose-based polymer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2900048B1 (fr) * 2006-04-21 2012-11-16 Oreal Compositions comprenant un derive diphenyl-methane hydroxyle
US20100040696A1 (en) * 2008-08-12 2010-02-18 Ilse Sente Composite Particles Having An Antioxidant-Based Protective System, And Topical Compositions Comprising The Same
FR2940615B1 (fr) * 2008-12-30 2011-12-30 Oreal Association de monosaccharides avec des agents antioxydants et son utilisation en cosmetique
FR2954144B1 (fr) * 2009-12-18 2012-01-27 Oreal Utilisation d'un polymere a titre d'agent antioxydant
US20180325804A1 (en) * 2017-05-12 2018-11-15 Shaklee Corporation Topical muscadine formulation for cosmetic use

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004203835A (ja) * 2002-12-26 2004-07-22 Nisshin Kagaku Kk フェルラ酸含有組成物
WO2014059225A1 (en) * 2012-10-12 2014-04-17 L'oreal Cosmetic compositions containing at least one flavonoid and ferulic acid
WO2017172519A1 (en) * 2016-03-31 2017-10-05 L'oreal Photo-stabilized compositions and methods of use
US10137072B2 (en) * 2016-03-31 2018-11-27 L'oreal Methods and compositions for providing broad spectrum photo protection using antioxidants
WO2018081790A1 (en) * 2016-10-31 2018-05-03 L'oreal Compositions containing phenolic compounds having synergistic antioxidant benefits
CN107638331A (zh) * 2017-08-31 2018-01-30 澳宝化妆品（惠州）有限公司 一种修护皮肤屏障且抵抗自由基的保湿乳液
WO2020099664A1 (en) * 2018-11-15 2020-05-22 L'oreal Composition comprising a cinnamic acid derivative and a nonassociative nonionic cellulose-based polymer

Also Published As

Publication number Publication date
FR3118579B1 (fr) 2024-04-19
FR3118579A1 (fr) 2022-07-08
CN116669688A (zh) 2023-08-29

Similar Documents

Publication Publication Date Title
US10532017B2 (en) Stable antioxidant compositions
JP4901025B2 (ja) エラスターゼ阻害剤
US7399783B2 (en) Methods for the treatment of scar tissue
KR20090038460A (ko) 국소 피부 조성물, 이들의 제조 및 이들의 용도
US20230139504A1 (en) Cosmetic compositions comprising high amounts of hydroxypropyl tetrahydropyrantriol
CA3151698A1 (en) Skin lightening composition
JP2003002819A (ja) 皮膚組成物
WO2022141375A1 (en) Composition for caring for kertatin materials
EP4422760A1 (en) Cosmetic compositions comprising high amounts of retinol
EP4271350A1 (en) Composition for caring for kertatin materials
JP2006008537A (ja) 皮膚外用剤
JP3940633B2 (ja) 皮膚外用剤
US12090224B2 (en) Cosmetic composition comprising high amounts of ceramide-np
US12064504B2 (en) Cosmetic compositions comprising high amounts of trifluoromethylhenyl valylglycine
WO2024178529A1 (en) Colorant composition for dyeing keratin fibers and kit comprising the same
Ali Phenolics for skin photo-aging.
CN118284402A (zh) 包含大量视黄醇的化妆品组合物
CN118201589A (zh) 包含大量神经酰胺-np的化妆品组合物
WO2023120260A1 (en) Composition comprising solubilized polyphenol
CN116634982A (zh) 用于护理角蛋白材料的组合物
JP2003335628A (ja) 皮膚外用剤
JP2003137727A (ja) 皮膚外用剤
JP2003306423A (ja) 皮膚外用剤
FR3132217A1 (fr) Compositions cosmétiques comprenant des quantités élevées de trifluorométhylphényl valylglycine
Draelos 11 Cosmeceutical Botanicals

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20967714

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 202080108286.9

Country of ref document: CN

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 20967714

Country of ref document: EP

Kind code of ref document: A1