WO2022130950A1 - Vanne de commutation de circuit d'écoulement et chromatographe en phase liquide - Google Patents

Vanne de commutation de circuit d'écoulement et chromatographe en phase liquide Download PDF

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Publication number
WO2022130950A1
WO2022130950A1 PCT/JP2021/043600 JP2021043600W WO2022130950A1 WO 2022130950 A1 WO2022130950 A1 WO 2022130950A1 JP 2021043600 W JP2021043600 W JP 2021043600W WO 2022130950 A1 WO2022130950 A1 WO 2022130950A1
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WIPO (PCT)
Prior art keywords
flow path
rotor
rotor seal
stator
switching valve
Prior art date
Application number
PCT/JP2021/043600
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English (en)
Japanese (ja)
Inventor
綾乃 大坪
光宏 松澤
修大 塚田
久雄 稲波
充彦 植田
将司 富田
健一郎 西木
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株式会社日立ハイテク
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Publication of WO2022130950A1 publication Critical patent/WO2022130950A1/fr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns

Definitions

  • the present invention relates to a flow path switching valve and a liquid chromatograph.
  • Analytical devices such as liquid chromatographs are equipped with a flow path switching valve that switches between a large number of flow paths.
  • the flow path switching valve is composed of a stator for connecting pipes, a rotor seal, a rotor for rotating the rotor seal, a housing for holding them, and the like.
  • the rotor seal is pressed against the stator by a spring or the like, and liquidtightness is maintained between the flow path formed in the rotor seal and the flow path formed in the stator.
  • the rotor seal is fixed to the rotor by a pin, and by rotating the rotor by a motor, the rotor seal also rotates, and the flow path of the rotor seal is switched with respect to the flow path of the stator.
  • Patent Document 1 shows a flow path switching valve having a structure for suppressing wear of the sliding surface.
  • the flow path switching valve of Patent Document 1 provides at least three grooves and a port opening cross section for valve damage during switching from injection to loading, as well as loading from the injection position as a result of its configuration and selected rotational direction. It is characterized by releasing the sample loop pressure under high pressure as the rotor rotates to position.
  • the flow path switching valve of Patent Document 2 is a compliance assembly that cooperates with the rotor device so that the substantially flat rotor surface is oriented substantially parallel to the substantially flat stator surface of the stator device and in substantially the same plane. Be prepared. Also, the rotor device defines a base-facing contact surface facing away from the rotor surface, and the compliance assembly comprises a compliant element that supports the contact surface of the rotor device in a supportive joint contact.
  • the present invention has been made to solve such a problem, and an object of the present invention is to provide a flow path switching valve and a liquid chromatograph capable of further suppressing wear on the sliding surface between the rotor seal and the stator.
  • An example of the flow path switching valve according to the present invention is A flow path switching valve comprising a stator, a rotor seal that rotates while in contact with the stator, and a rotor that rotates the rotor seal.
  • a plurality of stator flow paths are formed in the stator by through holes.
  • the rotor seal includes a first member that comes into contact with the stator via a sliding surface and a second member that comes into contact with the first member.
  • a first rotor flow path is formed in the first member, and a second rotor flow path is formed in the second member.
  • the cross-sectional area of the first rotor flow path on the sliding surface is smaller than the cross-sectional area of the second rotor flow path on the surface parallel to the sliding surface.
  • An example of the liquid chromatograph according to the present invention includes the above-mentioned flow path switching valve, a liquid feed pump, a needle, a syringe pump, a separation column, and a detector.
  • This specification includes the disclosure of Japanese Patent Application No. 2020-207324, which is the basis of the priority of the present application.
  • FIG. 1 The figure which shows the example of the structure of the flow path switching valve which concerns on Example 1 of this invention.
  • FIG. 1 The figure which shows the example of the structure of the flow path switching valve which concerns on Example 2 of this invention and the modified example thereof.
  • FIG. 1 shows an example of the configuration of the flow path switching valve 1 according to the first embodiment of the present invention.
  • FIG. 1A shows a cross-sectional view of the flow path switching valve 1 in a plane parallel to the axis (for example, the axis of rotation, the same applies hereinafter).
  • FIG. 1A is based on a cross section 19 shown by a broken line in FIG. 1D.
  • the flow path switching valve 1 includes a stator 11 and a rotor 14 as shown in FIG. 1 (a). Further, the flow path switching valve 1 includes a rotor seal.
  • the rotor seal includes a rotor seal 12 (first member of the rotor seal) and a rotor seal 13 (second member of the rotor seal).
  • the rotor seal 12 contacts the stator 11 via the contact surface 18.
  • the contact surface 18 serves as a sliding surface.
  • the rotor seal 13 comes into contact with the rotor seal 12.
  • the flow path switching valve 1 includes a housing 15 for accommodating the stator 11 and the rotor 14.
  • the rotor seals 12 and 13 are coupled to the rotor 14 via pins 16 and 17, and the rotor 14 rotates the rotor seals 12 and 13.
  • the rotor seal (rotor seal 12 in this example) rotates while being in contact with the stator 11.
  • the rotation angle of the rotor 14 is measured, for example, by equipping the motor (not shown) with an encoder.
  • FIG. 1B is a view of the upper surface of the rotor seal 13 as viewed from above.
  • FIG. 1C is a view of the upper surface of the rotor seal 12 (that is, the portion related to the contact surface 18 with the stator 11) as viewed from above.
  • FIG. 1D is a perspective view of the lower surface of the stator 11 (that is, the portion related to the contact surface 18 with the rotor seal 12) as viewed from above.
  • 1 (e) is a perspective view showing a state in which the rotor seals 12 and 13 are rotated in the sliding direction 211 from the state of FIG. 1 (d).
  • a plurality of stator flow paths 111 to 116 are formed in the stator 11 by through holes.
  • a plurality of rotor seal flow paths 121 to 126 (first rotor flow path) are formed in the rotor seal 12.
  • the rotor seal flow paths 121 to 126 are formed, for example, by through holes.
  • a plurality of rotor seal flow paths 131 to 133 (second rotor flow path) are formed in the rotor seal 13.
  • the rotor seal flow paths 131 to 133 are formed by, for example, a groove formed on the upper surface of the rotor seal 13.
  • the upper surface of the rotor seal flow path 131 to 133 is formed by the surface (lower surface) of the rotor seal 12, and the side surface and the lower surface of the rotor seal flow path 131 to 133 are formed by the groove of the rotor seal 13.
  • the diameter of the flow path may be different from the actual one.
  • the cross section of the stator flow path 111 is drawn smaller than the cross section of the rotor seal flow path 121, but in reality, these diameters can be configured to be equal. The same applies to FIGS. 3, 4 and 7 described later.
  • External piping is connected to the stator flow paths 111 to 116.
  • the rotor seal flow paths 121 to 126 of the rotor seal 12 are connected to different stator flow paths 111 to 116 according to the rotation of the rotor seal 12.
  • the rotor seal flow paths 121, 122, 123, 124, 125, 126 are connected to the stator flow paths 111, 112, 113, 114, 115, 116, respectively, but FIG.
  • the rotor seal flow paths 121, 122, 123, 124, 125, 126 are connected to the stator flow paths 112, 113, 114, 115, 116, 111, respectively.
  • the rotor seal flow paths 131 to 133 of the rotor seal 13 connect two of the rotor seal flow paths 121 to 126, respectively.
  • the rotor seal flow path 131 connects the rotor seal flow path 121 and the rotor seal flow path 122.
  • the stator flow path 111, the rotor seal flow path 121, the rotor seal flow path 131, the rotor seal flow path 122, and the stator flow path 112 are A flow path is formed in order. Two other similar channels are formed.
  • connection relationship between the flow paths is also fixed.
  • the connection relationship between the rotor seal flow paths 131 to 133 and the rotor seal flow paths 121 to 126 may be changed automatically or manually.
  • the stator 11 is made of, for example, metal or ceramic.
  • the rotor seals 12 and 13 are made of, for example, metal, ceramic, or resin.
  • the stator 11 and the rotor seal 12 forming the sliding surface may be coated with diamond-like carbon in order to improve wear resistance.
  • the rotor seals 12 and 13 are pressed against the stator 11 by a spring (not shown) of the rotor 14, which normally maintains liquidtightness.
  • FIG. 2 shows the operation of the flow path switching valve according to the prior art.
  • 2 (a) to 2 (c) are perspective views of the lower surface of the stator (that is, the contact surface with the rotor seal 222) (that is, the contact surface with the rotor seal 222), which is not shown, and corresponds to FIG. 1 (c).
  • the rotor seal 222 is composed of a single member. From the state of FIG. 2A, the rotor seal 222 rotates 60 degrees in the sliding direction 211, and after passing through the state of FIG. 2B, the state of FIG. 2C is reached.
  • the rotor seal flow path 241 connects the stator flow paths 31 and 32 in the state of FIG. 2A, and connects the stator flow paths 32 and 33 in the state of FIG. 2C.
  • the rotor seal flow path 242 connects the stator flow paths 33 and 34 in the state of FIG. 2 (a), and connects the stator flow paths 34 and 35 in the figure (c).
  • the rotor seal flow path 243 connects the stator flow paths 35 and 36 in the state of FIG. 2A, and connects the stator flow paths 36 and 31 in the state of FIG. 2C.
  • the state of FIG. 2 (c) is rotated 60 degrees in the direction opposite to the sliding direction 211, and the state of FIG. 2 (b) is changed. After that, the state returns to the state of FIG. 2 (a). In this way, the rotor seal 222 reciprocates by repeating the rotation of 60 degrees in the sliding direction 211 (counterclockwise) and the rotation of 60 degrees in the direction opposite to the sliding direction 211 (clockwise).
  • FIG. 3 shows a schematic flow path diagram of the liquid chromatograph 21 equipped with the flow path switching valve 1 according to the first embodiment of the present invention.
  • the liquid chromatograph 21 includes a flow path switching valve 1, a liquid feed pump 22, a needle 23, a syringe pump 24, a separation column 26, a detector 27, and a pipe 210 connecting them.
  • stator flow paths 111, 112, 113, 114, 115, 116 of the flow path switching valve 1 are connected to the liquid feed pump 22, the pipe 2101, the needle 23, the syringe pump 24, the pipe 2101, and the separation column 26, respectively.
  • the liquid feed pump 22 feeds the eluent 29.
  • the eluent 29 includes the stator flow path 111, the rotor seal flow path 121, 131, 122, the stator flow path 112, the pipe 2101, the stator flow path 115, the rotor seal flow path 125, 133, 126, and the stator flow path 116 in this order. It flows through the separation column 26, the detector 27, and the waste liquid tank 281.
  • the needle 23 is connected to the syringe pump 24 and the waste liquid tank 282 via the stator flow path 113, the rotor seal flow path 123, 132, 124, and the stator flow path 114.
  • Sample 8 includes a needle 23, a stator flow path 113, a rotor seal flow path 122, 131, 121, a stator flow path 112, a pipe 2101, a stator flow path 115, a rotor seal flow path 124, 132, 123, a stator flow path 114, and the like. Is sucked through in this order, and at least a part of the sample 8 is held in the pipe 2101.
  • the eluent 29 fed by the liquid feed pump 22 passes through the stator flow path 111, the rotor seal flow path 126, 133, 125, and the stator flow path 116 in this order. It flows to the separation column 26, the detector 27, and the waste liquid tank 281.
  • the liquid feed pump 22 is driven to feed the sample 8 in the stator flow path 111, the rotor seal flow path 121, 131, 122, the stator flow path 112, and the pipe 2101 to the separation column 26. Liquid.
  • the sample 8 is separated by the separation column 26 and then detected by the detector 27. Then, the eluent is sent to clean the entire flow path including the pipe 210. Then, FIGS. 3 (a) and 3 (b) are repeated for analysis of another sample.
  • the separation column 26 is filled with particles of several micrometers inside and has a large fluid resistance. Further, in order to improve the sample separation performance of the separation column 26, the flow path diameter of the pipe 210 is small (for example, 0.1 mm), and the fluid resistance is large. Therefore, the liquid feed pump 22 feeds the eluate at a high pressure of several tens of megapascals. On the other hand, since a member having a large fluid resistance is not connected to the flow path connected to the syringe pump 24, the liquid feeding pressure of the syringe pump 24 is close to the atmospheric pressure (0.1 MPa). As described above, in the configuration of the liquid chromatograph 21 according to the first embodiment, the high pressure and low pressure solutions flow simultaneously in the separate rotor seal flow paths in the flow path switching valve 1.
  • FIG. 2 shows the operation of the flow path switching valve according to the prior art as described above.
  • FIG. 4 shows the operation of the flow path switching valve 1 according to the first embodiment.
  • 4 (a) to 4 (c) are perspective views of the lower surface of the stator 11 (that is, the contact surface 18 with the rotor seal 12) as viewed from above, and correspond to FIG. 1 (c). Similar to FIG. 2, the rotor seals 12 and 13 rotate 60 degrees in the sliding direction 211 from the state of FIG. 4 (a), go through the state of FIG. 4 (b), and become the state of FIG. 4 (c). ..
  • the pressure generated in the immediately preceding state (for example, the state of FIG. 2A) is maintained.
  • the hydraulic pressure in the rotor seal flow paths 241 and 243 is high, and the hydraulic pressure in the rotor seal flow path 242 is low.
  • the space between the rotor seal 222 and the stator (not shown) is expanded by the hydraulic pressure, and the rotor seal 222 is tilted.
  • the contact pressure of the region 200 facing the rotor seal flow paths 241 and 243 increases.
  • a high-pressure liquid feed pump is connected to the rotor seal flow path 243, and a low-pressure syringe pump is connected to the rotor seal flow paths 241 and 242.
  • the hydraulic pressure in the rotor seal flow paths 241 and 242 is high, and the hydraulic pressure in the rotor seal flow paths 241 and 242 is low. Therefore, in the vicinity of the rotor seal flow path 243, the space between the rotor seal 222 and the stator (not shown) is expanded by the hydraulic pressure, and the rotor seal 222 is tilted. As a result, the contact pressure of the region 200 facing the rotor seal flow path 243 increases.
  • the rotor seal of the flow path switching valve uses a metal or ceramic with a hard surface from the viewpoint of wear resistance.
  • the surfaces of metals and ceramics are hard, and it is difficult to process an arcuate flow path as shown in FIG. 2A with a narrow flow path width. Therefore, the flow path width 2411 of the rotor seal flow path is large, and the area of the rotor seal flow path 241 in contact with the stator is large, so that the force received by the hydraulic pressure is large. Due to this force, the rotor seal 222 is tilted as described above, and the contact pressure increases in a part of the region 200. If the rotor seal 222 rotates in this state, wear occurs on the contact surface.
  • the conventional flow path switching valve reciprocates between the state of FIG. 2 (a) and the state of FIG. 2 (c).
  • wear of the region facing the rotor seal flow path through which the high-pressure solution flows progresses.
  • the valve does not function as a valve, so that the life of the flow path switching valve may be shortened.
  • the operation of the flow path switching valve 1 is as follows. From the state of FIG. 4A, the rotor seals 12 and 13 rotate 60 degrees in the sliding direction 211, and after passing through FIG. 4B, the state of FIG. 4C is reached.
  • the rotor seal flow paths 121, 131, and 122 are connected to the stator flow paths 111 and 112 in FIG. 4 (a), but are switched to the stator flow paths 112 and 113 in FIG. 4 (c).
  • the rotor seal flow paths 123, 132, and 124 are connected to the stator flow paths 113 and 114 in FIG. 4A, but are switched to the connection with the stator flow paths 114 and 115 in FIG. 4C.
  • the rotor seal flow paths 125, 133, and 126 are connected to the stator flow paths 115 and 116 in FIG. 4A, but are switched to the connection with the stator flow paths 116 and 111 in FIG. 4C.
  • the high-pressure liquid feed pump 22 is connected to the rotor seal flow paths 121, 131, 122 and the rotor seal flow paths 125, 133, 126, and the hydraulic pressure becomes high.
  • a low-pressure syringe pump 24 is connected to the rotor seal flow paths 123, 132, 124, and the hydraulic pressure becomes low. Then, in the vicinity of the rotor seal flow paths 121, 122, 125, 126, the space between the rotor seal 12 and the stator 11 is expanded by the hydraulic pressure.
  • each rotor seal flow path is formed inside the rotor seal and is not configured to extend along the lower surface of the stator 11, so that the force that the lower surface of the stator 11 receives from the hydraulic pressure is conventional.
  • the cross-sectional area of the rotor seal flow paths 121 to 126 on the contact surface 18 is the contact surface 18 of the rotor seal flow paths 131 to 133. It is smaller than the cross-sectional area in parallel planes (indicated by three wide arcuate regions in FIG. 1 (d)).
  • the cross-sectional area of each of the rotor seal flow paths 121 to 126 is smaller than the cross-sectional area of any of the rotor seal flow paths 131 to 133.
  • the force to spread between the rotor seal 12 and the stator 11 becomes small. Then, it is possible to suppress an increase in the contact pressure of the region 201 facing the rotor seal flow path through which the high-pressure solution flows. Therefore, the progress of wear of the region 201 facing the rotor seal flow path through which the high-pressure solution flows is slowed down, and the life of the flow path switching valve is extended.
  • the region 201 is shown narrower than the region 200 of FIG. 2, indicating that the contact pressure is smaller.
  • the flow path switching valve 1 is provided with the rotor seal 12 and the rotor seal 13 to provide a part of the rotor seal flow path (in this example, the rotor). Since the seal flow path 131 to 133) can be arranged inside the rotor seal, it is not necessary to form the rotor seal flow path along the lower surface of the stator 11. Therefore, the area of the rotor seal flow path in the portion in contact with the stator 11 becomes smaller than before, and the force for pushing the rotor seal 12 between the stator 11 and the rotor seal 12 due to the hydraulic pressure becomes smaller. As a result, the inclination of the rotor seal 12 becomes smaller, and an increase in contact pressure in a part of the region can be suppressed.
  • the configuration (area, etc.) of the rotor seal flow paths 131 to 133 in the rotor seal 13 can be the same as the configuration of the rotor seal flow paths 241 to 243 in the conventional rotor seal 222.
  • the space between the rotor seal 12 and the rotor seal 13 may be widened, and the rotor seal 13 may be tilted with respect to the rotor seal 12.
  • the rotor seal 12 is arranged between the rotor seal 13 and the stator 11, the inclination is dispersed by the rotor seal 12, and the force can be dispersed.
  • the inclination can be further suppressed.
  • the rotor seal 12 out of a metal harder than the rotor seal 13, the rotor seal 12 can alleviate the deformation of the rotor seal 13 and suppress the inclination of the rotor seal 12.
  • the surface of the rotor seal 12 is made of a hard material (for example, metal or ceramic), it is possible to make a fine through hole in the rotor seal 12. Therefore, by providing the rotor seal 12 with the rotor seal flow paths 121 to 126 having fine through holes, the area of the portion of the rotor seal flow path in contact with the stator 11 can be made smaller than before.
  • the flow path switching valve 1 As described above, according to the flow path switching valve 1 according to the first embodiment of the present invention, it is possible to suppress an increase in the contact pressure in a part of the region (for example, the region facing the rotor seal flow path through which the high-pressure solution flows). Therefore, the progress of wear in the region can be suppressed, and the life of the flow path switching valve 1 is extended.
  • Example 2 In the second embodiment, the rotor seal is integrated by diffusion joining or the like in the first embodiment.
  • the second embodiment will be described, but the description of the parts common to the first embodiment may be omitted.
  • FIG. 5A shows an example of the configuration of the flow path switching valve 1 according to the second embodiment of the present invention.
  • FIG. 5B shows an example of the configuration of the flow path switching valve 1 according to the first modification of the second embodiment of the present invention.
  • the rotor seal 12 and the rotor seal 13 are integrated by diffusion joining.
  • the rotor seal 514 of FIG. 5A is a rotor seal in which the rotor seals 712 and 713 are bonded and integrated by diffusion bonding.
  • Rotor seal flow paths 722, 725, 732, 735, etc. are formed on the rotor seals 712 and 713.
  • the rotor seal 514 is integrated by diffusion joining, the number of assembly steps of the flow path switching valve 1 can be reduced. Further, the vertical dimension of the entire rotor seal 514 can be reduced, and the pins 16 and 17 can be shortened. This improves, for example, the assembleability of the flow path switching valve 1.
  • the rotor seals 712 and 713 are arranged inside the rotor seal outer member 714. Also in this example, the rotor seals 712 and 713 are integrated by diffusion joining. The rotor seals 712 and 713 are coupled to the rotor seal outer member 714 by pins 161 and 171. The rotor seals 712, 713, and 714 may be diffusion-bonded without using the pins 161 and 171.
  • the area of diffusion bonding can be reduced as compared with the structure of FIG. 5 (a), and the cost can be reduced.
  • FIG. 6 shows an example of the configuration of the rotor seal 514 in the flow path switching valve according to the modified example of the second embodiment of the present invention.
  • 6 (a) shows a second modification of Example 2
  • FIG. 6 (b) shows a third modification of Example 2
  • FIG. 6 (c) shows a fourth modification of Example 2. ..
  • FIG. 1A of Example 1 if the area of the contact surface 18 of the rotor seals 12 and 13 is increased, it may be difficult to manufacture the rotor seals 12 and 13 from the viewpoint of maintaining the liquidtightness between the rotor seals 12 and 13.
  • the area of the contact surface 20 can be made larger. Therefore, as shown in FIGS. 6A to 6C, the shapes of the rotor seals 712 and 713 can be designed more freely.
  • the diameters of the rotor seals 712 and 713 are the same, and the gutter 601 is formed in the rotor seal 712.
  • the gutter 601 is a rotary groove extending in the circumferential direction on the radial outer circumference of the rotor seal 712. Since the pressure is not transmitted in the vertical direction in the side groove 601 part, the force for tilting the rotor seal 712 can be concentrated in the central region, and the rotational moment for tilting the rotor seal 712 (for example, generated perpendicular to the flow path switching valve 1 axis). ) Can be suppressed to reduce the inclination.
  • the diameters of the rotor seals 712 and 713 are the same, and the gutter 601 is formed in the rotor seal 713. Also in this example, the force for tilting the rotor seal 712 can be concentrated in the central region to reduce the tilt.
  • the bottom groove 602 is formed in the rotor seal 713.
  • the rotor seals 712 and 713 are integrated by diffusion joining or the like, the number of assembly steps of the flow path switching valve 1 can be reduced. Further, the vertical dimension of the entire rotor seal 514 can be reduced, and the pin can be shortened. This improves, for example, the ease of assembling the flow path switching valve.
  • Example 3 In the third embodiment, in the first embodiment, the pitch circle diameters of the rotor seal flow paths 131 to 133 are made smaller.
  • the third embodiment will be described, but the description of the parts common to the first embodiment may be omitted.
  • FIG. 7 shows an example of the configuration of the flow path switching valve 1 according to the third embodiment of the present invention.
  • 7 (a) to 7 (e) correspond to FIGS. 1 (a) to 1 (e) in the first embodiment, respectively.
  • FIG. 7A is based on the cross section 83 shown by the broken line in FIG. 7D.
  • the flow path switching valve 1 according to the third embodiment is different from the first embodiment in the structure of the rotor seal flow path, the flow path diameter of the rotor seal flow path, and the pitch circle diameter related to the rotor seal flow path.
  • the flow path switching valve 1 according to the third embodiment includes a stator 61 instead of the stator 11 of the first embodiment. Further, the flow path switching valve 1 according to the third embodiment includes rotor seals 812 and 813 instead of the rotor seals 12 and 13 of the first embodiment.
  • the rotor seal 812 includes rotor seal flow paths 121 to 126 extending at an angle 82 with respect to the contact surface 18 with the stator 61 (however, FIG. 7 (a) shows a rotor. Only the sealed flow paths 122 and 125 appear).
  • the angle 82 is an angle formed by the center line 80 (axis line) of the flow path switching valve 1 and the center line 81 of each of the stator flow paths 111 to 116. That is, the stator flow paths 111 to 116 and the rotor seal flow paths 121 to 126 are configured so that the pair connected to each other is parallel to each other. In this way, the stator 61 and the rotor seal 812 are configured with an inclination so that the flow paths approach each other from top to bottom.
  • the rotor seal flow paths 121 to 126 of the rotor seal 812 have an end portion (first end) on the contact surface 18 side and an end portion on the opposite side to the contact surface 18. (Second end) is provided.
  • the end portion on the contact surface 18 side is formed on the pitch circle 85 (first circle), and the end portion on the opposite side to the contact surface 18 is formed on the pitch circle 84 (second circle).
  • the diameter of the pitch circle 85 is larger than the diameter of the pitch circle 84. Since the rotor seal flow paths 131 to 133 of the rotor seal 813 are configured to connect the rotor seal flow paths 121 to 126, they are formed on the pitch circle 84 (second circle).
  • the formation of the rotor seal flow paths 131 to 133 in the rotor seal 813 is a fine process, but if the process is difficult, the rotor seal 813 can be made of a softer material than the rotor seal 812. It is possible to make the processing of the flow path easier. In that case, further reduce the flow path width 1311 (FIG. 7 (b)) of the rotor seal flow paths 131 to 133 and the flow path diameter 1211 (FIG. 7 (c)) of the rotor seal flow paths 121 to 126. The area of the rotor seal flow path in contact with the stator 61 can be further reduced.
  • the rotor seal flow paths 131 to 133 can be formed at a position closer to the center, so that the spread between the rotor seal 812 and the rotor seal 813 can be suppressed.
  • the inclination of the rotor seal 813 with respect to the rotor seal 812 can be suppressed.
  • the rotor seal and the stator do not spread, and it is possible to suppress an increase in the contact pressure in the region facing the rotor seal flow path through which the high-pressure solution flows. This slows the progress of wear in some areas and prolongs the life of the flow path switching valve. It should be noted that the flow path width and flow path diameter of the rotor seal flow path can be made small, and the analysis performance is maintained high.

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Abstract

L'invention concerne une vanne de commutation de circuit d'écoulement et un chromatographe en phase liquide qui sont plus aptes à supprimer l'usure sur une surface coulissante entre un joint de rotor et un stator.　Une vanne de commutation de circuit d'écoulement (1) comprend : un stator (11) ; des joints de rotor (12, 13) qui tournent tout en étant en contact avec le stator (11) ; et un rotor (14) qui fait tourner les joints de rotor (12, 13). Le stator (11) a une pluralité de circuits d'écoulement de stator (111-116) constitués de trous traversants. Les joints de rotor (12, 13) comprennent un premier élément (12) qui vient en contact avec le stator (11) par l'intermédiaire d'une surface de contact (18) et un second élément (13) qui vient en contact avec le premier élément (12). Des premiers circuits d'écoulement de rotor (121-126) sont formés dans le premier élément (12) et des seconds circuits d'écoulement de rotor (131-133) sont formés dans le second élément (13). L'aire en section transversale de la surface de coulissement (18) des premiers circuits d'écoulement de rotor (121-126) est inférieure à l'aire en section transversale d'un plan parallèle à la surface de coulissement (18) des seconds circuits d'écoulement de rotor (131-133).
PCT/JP2021/043600 2020-12-15 2021-11-29 Vanne de commutation de circuit d'écoulement et chromatographe en phase liquide WO2022130950A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020-207324 2020-12-15
JP2020207324A JP7474691B2 (ja) 2020-12-15 2020-12-15 流路切替バルブおよび液体クロマトグラフ

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WO2022130950A1 true WO2022130950A1 (fr) 2022-06-23

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014106213A (ja) * 2012-11-30 2014-06-09 Hitachi High-Technologies Corp 液体クロマトグラフ用オートサンプラ
WO2015122253A1 (fr) * 2014-02-12 2015-08-20 株式会社日立ハイテクノロジーズ Vanne de commutation de trajet d'écoulement et dispositif de chromatographie liquide utilisant une telle vanne
JP2016173249A (ja) * 2015-03-16 2016-09-29 王子ホールディングス株式会社 サンプル供給装置
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WO2021075184A1 (fr) * 2019-10-17 2021-04-22 株式会社日立ハイテク Vanne de commutation de chemin d'écoulement, système de vanne de commutation de chemin d'écoulement et chromatographe en phase liquide

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